O'Higgins Region Vacations & Trips from $618

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your O'Higgins Region Vacation

See and do more with a vacation package to O'Higgins Region. Whether you're going for the culture, festivals, history, or something else, our package deals make travel planning simple. A trip to O'Higgins Region wouldn't be complete without exploring some of its best cities, starting with Santa Cruz. A couple of the top attractions here include Lapostolle Clos Apalta Winery and Casino Colchagua. Rancagua should also be on the itineraries of all O'Higgins Region travelers. Visitors to this exciting destination enjoy Parque Safari Chile and Reserva Nacional Rio Cipreses. Expedia has hotels, flights and whatever else you need to help you curate your own tailored O'Higgins Region vacation today.

Top destinations in O'Higgins Region

Meanders at the delta river Rapel in the town of La Boca. An amazing view of the bends of the river looking for an exit to the Pacific Ocean in between the valleys, hills and forests an awe landscape
FlightsFlightsHotelsHotels

Navidad

Navidad

The Latest O'Higgins Region Vacation Packages

Price found within the past 48 hours. Click for updated prices.
LOFT Hotel by Sommelier Hoteles

LOFT Hotel by Sommelier Hoteles

3 out of 5
Downtown Santiago
Price was $952, price is now $618 per person
$618
per person
Sep 12 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
San José (SJO) to Santiago (SCL)
9/10 Wonderful! (256 reviews)
It was great to have breakfast delivered to the room as part of the stay. The location was perfect, walkable to all parts of downtown that you would want to see. Easy to grab train and bus to get to airport.

Reviewed on Jun 12, 2026

Hotel Nodo - El primer hotel de negocios en Chile

Hotel Nodo - El primer hotel de negocios en Chile

3.5 out of 5
Providencia
Price was $1,062, price is now $654 per person
$654
per person
Sep 12 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
San José (SJO) to Santiago (SCL)
8.6/10 Excellent! (109 reviews)
very good hotel, good location

Reviewed on Jan 7, 2026

Hotel Sommelier

Hotel Sommelier

3 out of 5
Downtown Santiago
Price was $991, price is now $638 per person
$638
per person
Sep 12 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
San José (SJO) to Santiago (SCL)
8.6/10 Excellent! (255 reviews)
Good location for visiting the sights of the central city. The room was very spacious, with a small kitchen and living space separate from the bedroom. The breakfast had a good range and was well stocked. The rooftop bar was a good spot for a refreshment after a day exploring the sights. The only negative was that our we could hear the noise from the bar in our 5th floor room.

Reviewed on May 12, 2026

Park Plaza Santiago

Park Plaza Santiago

4 out of 5
Providencia
Price was $1,103, price is now $788 per person
$788
per person
Aug 24 - Aug 30
found 1 day ago
Roundtrip non-stop flight included
San José (SJO) to Santiago (SCL)
8.4/10 Very Good! (1,004 reviews)
Buena ubicación, personal amable.

Reviewed on Jun 8, 2026

Hotel Bonaparte Boutique

Hotel Bonaparte Boutique

3.5 out of 5
Providencia
Price was $939, price is now $671 per person
$671
per person
Aug 10 - Aug 15
found 1 day ago
Roundtrip non-stop flight included
San José (SJO) to Santiago (SCL)
8.8/10 Excellent! (621 reviews)
Bien en todo lo que uno necesita para estar comodo

Reviewed on May 25, 2026

Find the Best O'Higgins Region Vacation Packages

OHiggins Region Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Arturo Merino Benitez Airport (SCL)
Top Sights
Punta de Lobos Beach, Lobos Point and Pichilemu Beach

O'Higgins Region Hotel Deals

Vik Chile

Vik Chile

5 out of 5
Valle de Millahue San Vicente O'Higgins
$1,089 nightly
The price is $1,089 total per night from Jun 26 to Jun 27
$1,089 total
Jun 26 - Jun 27
Vik Chile
Santa Cruz Plaza

Santa Cruz Plaza

4 out of 5
Plaza De Armas 286 Santa Cruz O'Higgins
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $104 total per night from Jul 5 to Jul 6
$104 total
Jul 5 - Jul 6
Santa Cruz Plaza
Diego De Almagro Rancagua

Diego De Almagro Rancagua

3 out of 5
Av.Libertador Bernardo O'Higgins 34 Rancagua O'Higgins
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $109 total per night from Jun 26 to Jun 27
$109 total
Jun 26 - Jun 27
Diego De Almagro Rancagua
See all 274 properties in O'Higgins Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in O'Higgins Region

Lapostolle Clos Apalta Winery

5/5(3 reviews)

You can enjoy a tasting or tour at Lapostolle Clos Apalta Winery during your travels to Santa Cruz. While in this relaxing area, you can savor the wineries and restaurants.

Lapostolle Clos Apalta Winery

Monticello Grand Casino and Convention Center

Why not try your luck with a visit to Monticello Grand Casino and Convention Center during your visit to Mostazal? Make some time to visit the casinos while you're in the area.

Monticello Grand Casino and Convention Center

Colchagua Valley Wine Route

4.5/5(7 reviews)

You can take time to visit Colchagua Valley Wine Route during your travels to Lolol. You can enjoy the wineries while in the area.

Colchagua Valley Wine Route

What to do in O'Higgins Region

Make Your Own Wine & Guided Vineyard Tour

Make Your Own Wine & Guided Vineyard Tour

$46
per adult
Make Your Own Wine & Guided Vineyard Tour
Lunch at Viu Manent

3 Day Chile Wine Luxury Tour

$2,390
per adult
3 Day Chile Wine Luxury Tour
See all activities in O'Higgins Region
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.