Orangeburg County Vacations & Trips from $580
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Top destinations in Orangeburg County
Santee
Orangeburg
Eutawville
Edisto
Holly Hill
Vance
Elloree
Bowman
Branchville
The Latest Orangeburg County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
- The Ryder Hotel
Aug 29 - Sep 1The Ryder Hotel + Flight
Charleston Historic District3 nights3.5 star property8.8/10 - Excellent (1,097 reviews)"Very clean room and property and very nice pool area and location, would definitely recommend staying here."Reviewed July 26, 2026Roundtrip • Boston (BOS) - Charleston (CHS)BOS - CHS • 1 stop CHS - BOS • 1 stop$806$580found 1 day agoper traveler - 137 Grand Pavilion by Avantstay Steps to Beach + Resort Pools Wild Dunes Gated
Oct 12 - Oct 17137 Grand Pavilion by Avantstay Steps to Beach + Resort Pools Wild Dunes Gated + Flight
Isle of Palms5 nights3.0 star propertyRoundtrip • Boston (BOS) - Charleston (CHS)BOS - CHS • Nonstop CHS - BOS • 1 stop - 1111 Middle Street by Avantstay Charming Historic Cottage Featured in "dear John" Movie Beach Access
Oct 12 - Oct 171111 Middle Street by Avantstay Charming Historic Cottage Featured in "dear John" Movie Beach Access + Flight
Sullivan's Island5 nights3.0 star propertyRoundtrip • Boston (BOS) - Charleston (CHS)BOS - CHS • Nonstop CHS - BOS • 1 stop - 1 Block to Beach, Newly Renovated 6bdr w/ Rooftop Views Sand Dune by Avantstay
Sep 19 - Sep 241 Block to Beach, Newly Renovated 6bdr w/ Rooftop Views Sand Dune by Avantstay + Flight
Downtown Isle of Palms5 nights3.5 star propertyRoundtrip • Philadelphia (PHL) - Charleston (CHS)PHL - CHS • Nonstop CHS - TTN • Nonstop - Isle Be There by Avantstay Shared Pool + Pickleball Court + Sunroom + Deck Walk to the Beach
Oct 12 - Oct 17Isle Be There by Avantstay Shared Pool + Pickleball Court + Sunroom + Deck Walk to the Beach + Flight
Isle of Palms5 nights3.0 star propertyRoundtrip • Boston (BOS) - Charleston (CHS)BOS - CHS • Nonstop CHS - BOS • 1 stop
Discover the most popular places to visit in Orangeburg County
Orangeburg County Hotel Deals
9.2 out of 10, Wonderful, (1,009 reviews)
9.2/10
Wonderful
(1,009 reviews)
"The staff helped us when our refrigerator wasn’t working in our room by finding a replacement while we were out to dinner and texted me to let me know it was taken care of. Everything was clean and well maintained otherwise and breakfast was great and the employee who was taking care of the buffet was sweet and doing a great job! Love Tru in Orangeburg,SC!"
$114 nightly
The price is $127
$127 total
Aug 9 - Aug 10
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg3.0 star property
4.2 mi from Orangeburg County
8.4 out of 10, Very Good, (803 reviews)
8.4/10
Very Good
(803 reviews)
"The elevator at Fairfield was not working. I was traveling with my elderly mother who couldn’t walk the stairs. The associate at the hotel referred me to another Marriott location where I ended up staying. The Expedia app changed me for the room anyway. The associate at Fairfield stated that I was not charged on their end. I’ve noticed several pending charges on my card. I’m still waiting for Expedia to waive the charges for a canceled stay at no fault of mine."
$110 nightly
The price is $122
$122 total
Jul 27 - Jul 28
Total with taxes and fees
Hampton Inn & Suites Orangeburg
Hampton Inn & Suites Orangeburg2.5 star property
4.6 mi from Orangeburg County
9.4 out of 10, Exceptional, (826 reviews)
9.4/10
Exceptional
(826 reviews)
"Rooms very clean. Staff friendly. Great Soĺection for breakfast
Plenty of Parking."
$130 nightly
The price is $145
$145 total
Aug 9 - Aug 10
Total with taxes and fees
7.8 out of 10, Good, (1,006 reviews)
7.8/10
Good
(1,006 reviews)
$98 nightly
The price is $108
$108 total
Aug 2 - Aug 3
Total with taxes and fees
9.2 out of 10, Wonderful, (889 reviews)
9.2/10
Wonderful
(889 reviews)
$98 nightly
The price is $108
$108 total
Aug 2 - Aug 3
Total with taxes and fees
7.6 out of 10, Good, (456 reviews)
7.6/10
Good
(456 reviews)
$68 nightly
The price is $76
$76 total
Aug 21 - Aug 22
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee3.0 star property
22.4 mi from Orangeburg County
9.8 out of 10, Exceptional, (1,002 reviews)
9.8/10
Exceptional
(1,002 reviews)
$134 nightly
The price is $149
$149 total
Aug 2 - Aug 3
Total with taxes and fees
8.0 out of 10, Very Good, (1,466 reviews)
8.0/10
Very Good
(1,466 reviews)
"Room was clean, area quiet. Glad they accepted pets"
$80 nightly
The price is $89
$89 total
Jul 27 - Jul 28
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.