Orangeburg County Vacations & Trips from $536
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Your Orangeburg County Vacation
Reserve a vacation package to Orangeburg County and make planning your getaway quick and easy. With all the logistics organized before you leave, you can focus on enjoying every second in this interesting destination. With so much to do and see on a trip to Orangeburg County, it can be difficult to know where to start. Kick off your journey in Santee at Santee State Park and Santee Cooper Country Club — two much-loved attractions here. Another great city worth adding to your itinerary is Orangeburg. Be sure not to miss Edisto Memorial Gardens and Smith-Hammond-Middleton Memorial Center. Whether you plan to travel for a couple of days or a couple of weeks, Expedia are here to help you customize your next Orangeburg County vacation.
Top destinations in Orangeburg County
The Latest Orangeburg County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Water's Edge Inn - Adults Only
$536
per person
Oct 28 - Oct 31
found 17 hours ago
Roundtrip flight included
Boston (BOS) to Charleston (CHS)
9.6/10 Exceptional! (495 reviews)
Our view was amazing, we were a very short walk from the beach (and an even shorter walk to the shops on main), and our hosts had many amenities we didn’t even know about from the booking. They provided happy hour drinks, fresh breakfast, free water bottles, and even golf cart rides to and from the beach. They were also incredibly kind and helpful any time we had questions. I wouldn’t change a single thing about our stay and will be coming back here next time I and my wife plan on coming back to Charleston.
Reviewed on Sep 9, 2026
Planters Inn
Charleston Historic District
$2,289
per person
Oct 17 - Oct 23
found 1 day ago
Roundtrip flight included
Boston (BOS) to Charleston (CHS)
9.6/10 Exceptional! (1,001 reviews)
This place is so beautiful. The room was so huge. The staff were so friendly and kind. Would definitely stay again in a heart beat. You can’t go wrong with this place. It was under construction in the lobby and restaurant wish we could have had dinner there so many next time!!!
Reviewed on Sep 7, 2026
Find the Best Orangeburg County Vacation Packages
Orangeburg County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Columbia Metropolitan Airport (CAE) |
Top Sights | Santee State Park, Edisto Memorial Gardens and Santee State Park |
Orangeburg County Hotel Deals
Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$98 nightly
$108 total
Oct 4 - Oct 5
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$134 nightly
$149 total
Sep 20 - Sep 21
Total with taxes and fees
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$79 nightly
$87 total
Sep 14 - Sep 15
Total with taxes and fees
8/10 Very Good! (1,487 reviews)
"Clean room. Friendly staff"
Reviewed on Sep 7, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Orangeburg County attractions
Santee State Park
8.0/10 (219 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.
Santee Cooper Country Club
7.8/10 (94 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.
Edisto Memorial Gardens
8.8/10 (110 reviews)
Explore the great outdoors at Edisto Memorial Gardens, a lovely green space in Orangeburg. While you're here, you can savor the top-notch restaurants.
Santee National Golf Club
8.0/10 (74 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.
Elloree Heritage Museum and Cultural Center
You can spend time browsing the exhibits at Elloree Heritage Museum and Cultural Center during your travels in Elloree.
Santee Town Hall
Santee Town Hall is just one of the places to see in Santee, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
