Orangeburg County Vacations & Trips from $984
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Your Orangeburg County Vacation
Reserve a vacation package to Orangeburg County and make planning your getaway quick and easy. With all the logistics organized before you leave, you can focus on enjoying every second in this interesting destination. With so much to do and see on a trip to Orangeburg County, it can be difficult to know where to start. Kick off your journey in Santee at Santee State Park and Santee Cooper Country Club — two much-loved attractions here. Another great city worth adding to your itinerary is Orangeburg. Be sure not to miss Edisto Memorial Gardens and Smith-Hammond-Middleton Memorial Center. Whether you plan to travel for a couple of days or a couple of weeks, Expedia are here to help you customize your next Orangeburg County vacation.
Top destinations in Orangeburg County
The Latest Orangeburg County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Ansonborough
Charleston Historic District
$984
per person
Nov 7 - Nov 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Charleston (CHS)
9.4/10 Exceptional! (1,183 reviews)
Great location with convenient self-parking ($35/day) across from the hotel. The room was large and comfortable but had a musty smell which did not dissipate during our three day stay. The breakfast was marginal but the staff handling the breakfast was great. There is a Harris Teeter supermarket right next door which was a real bonus for getting snacks and drinks. There was a rooftop sitting area with comfortable chairs which had a good view of the river.
Reviewed on Oct 4, 2026
The Restoration
Charleston Historic District
$1,050
per person
Nov 7 - Nov 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Charleston (CHS)
9.6/10 Exceptional! (1,254 reviews)
Great location, large rooms, very clean. Breakfast basket is cute but minimal.
Reviewed on Oct 4, 2026
Find the Best Orangeburg County Vacation Packages
Orangeburg County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Columbia Metropolitan Airport (CAE) |
Top Sights | Santee State Park, Edisto Memorial Gardens and Santee State Park |
Orangeburg County Hotel Deals
Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$101 nightly
$112 total
Oct 18 - Oct 19
Total with taxes and fees
9.2/10 Wonderful! (979 reviews)
"Everything is excellent!!"
Reviewed on Oct 3, 2026
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$80 nightly
$89 total
Oct 5 - Oct 6
Total with taxes and fees
8/10 Very Good! (1,495 reviews)
"Property was great for quick overnight stay off of 95 withy my dog. Walking distance to Cracker Barrel. I would definitely stay here again"
Reviewed on Oct 1, 2026
Fairfield Inn & Suites by Marriott Santee
9074 Old Number Six Hwy Santee SC
Fully refundableReserve now, pay when you stay
$139 nightly
$154 total
Oct 11 - Oct 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Orangeburg County attractions
Santee State Park
8.0/10 (219 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.
Santee Cooper Country Club
7.8/10 (94 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.
Santee National Golf Club
8.0/10 (74 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.
Edisto Memorial Gardens
8.8/10 (110 reviews)
Explore the great outdoors at Edisto Memorial Gardens, a lovely green space in Orangeburg. While you're here, you can savor the top-notch restaurants.
Santee Town Hall
Santee Town Hall is just one of the places to see in Santee, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
Smith-Hammond-Middleton Memorial Center
8.2/10 (36 reviews)
Catch an event at Smith-Hammond-Middleton Memorial Center during your trip to Orangeburg. While you're here, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
