Orangeburg County Vacations & Trips from $704
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Your Orangeburg County Vacation
Reserve a vacation package to Orangeburg County and make planning your getaway quick and easy. With all the logistics organized before you leave, you can focus on enjoying every second in this interesting destination. With so much to do and see on a trip to Orangeburg County, it can be difficult to know where to start. Kick off your journey in Santee at Santee State Park and Santee Cooper Country Club — two much-loved attractions here. Another great city worth adding to your itinerary is Orangeburg. Be sure not to miss Edisto Memorial Gardens and Smith-Hammond-Middleton Memorial Center. Whether you plan to travel for a couple of days or a couple of weeks, Expedia are here to help you customize your next Orangeburg County vacation.
Top destinations in Orangeburg County
The Latest Orangeburg County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
The Ryder Hotel
Charleston Historic District
$1,023
per person
Oct 16 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Charleston (CHS)
8.8/10 Excellent! (1,121 reviews)
Great vibe, convenient, beautiful pool and patio, comfortable beds, good food! We will stay here again!
Reviewed on Aug 13, 2026
The Charleston Place
Charleston Historic District
$2,367
per person
Oct 17 - Oct 23
found 1 day ago
Roundtrip flight included
Boston (BOS) to Charleston (CHS)
9.6/10 Exceptional! (1,008 reviews)
The property and the staff were A++ Everything was clean and staff was very friendly and helpful.
Reviewed on Aug 14, 2026
1blck to Beach, Pool, Outdoor Kitchen, Game Room Pelican by Avantstay
Beachwood East
$3,188
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
New York (NYC) to Charleston (CHS)
10/10 Exceptional! (2 reviews)
Amazing property! We had a family of 12 sleeping comfortably. Here for a family wedding, everything we needed was provided and then some, awesome location, definitely can’t wait to come back!
Reviewed on Dec 9, 2024
Find the Best Orangeburg County Vacation Packages
Orangeburg County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Columbia Metropolitan Airport (CAE) |
Top Sights | Santee State Park, Edisto Memorial Gardens and Santee State Park |
Orangeburg County Hotel Deals
Baymont by Wyndham Santee
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
$80 nightly
$89 total
Aug 16 - Aug 17
Total with taxes and fees
Tru By Hilton Santee
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
$98 nightly
$108 total
Aug 24 - Aug 25
Total with taxes and fees
9.2/10 Wonderful! (912 reviews)
"Muy limpio, muy bonito el hotel."
Reviewed on Aug 13, 2026
Super 8 by Wyndham, Orangeburg
3608 Saint Matthews Rd Orangeburg SC
$66 nightly
$73 total
Sep 7 - Sep 8
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Orangeburg County attractions
Santee State Park
8.0/10 (219 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.
Santee Cooper Country Club
7.8/10 (94 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.
Edisto Memorial Gardens
8.8/10 (110 reviews)
Explore the great outdoors at Edisto Memorial Gardens, a lovely green space in Orangeburg. While you're here, you can savor the top-notch restaurants.
Santee National Golf Club
8.0/10 (74 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.
Ferguson Island
Commune with nature and explore the great outdoors at Ferguson Island during your travels in Eutawville.
Smith-Hammond-Middleton Memorial Center
8.2/10 (36 reviews)
Catch an event at Smith-Hammond-Middleton Memorial Center during your trip to Orangeburg. While you're here, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
