Title: Ostiense Vacation Packages 2026 from $1,160 | Expedia.com [Ostiense Travel Guide](https://expedia.com/Rome-Ostiense.dx6227596)[Hotels in Ostiense](https://expedia.com/Ostiense-Rome-Hotels.0-n6227596-0.Travel-Guide-Filter-Hotels)[Flights to Rome](https://expedia.com/Cheap-Flights-To-Rome.d179899.Travel-Guide-Flights)[Things to do in Rome](https://expedia.com/Things-To-Do-In-Rome.d179899.Travel-Guide-Activities)[Car Rentals in Ostiense](https://expedia.com/Car-Rentals-In-Ostiense.d6227596.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6227596/f90e20ba-84aa-4ecb-a9fe-91e4de42a4b7.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Ostiense Vacations from $1,160 ## Book a Hotel + Flight or Car together to unlock savings ## Your Ostiense Vacation Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as [Roman Forum](https://www.expedia.com/Roman-Forum-Rome-City-Centre.d502481.Vacation-Attraction), [Pantheon](https://www.expedia.com/Pantheon-Rome-City-Centre.d502483.Vacation-Attraction) and [Piazza Navona](https://www.expedia.com/Piazza-Navona-Rome-City-Centre.d508631.Vacation-Attraction). Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia. ## The Latest Ostiense Vacation Packages Price found within the past 48 hours. Click for updated prices. ![Hotel Paolo II](https://images.trvl-media.com/lodging/18000000/17760000/17757300/17757261/1904ab07_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Paolo II Rome City Centre Save 100% on your flight $1,160 per person May 10 - May 16 found 11 hours ago Roundtrip flight included New York (JFK) to Rome (FCO) 9/10 Wonderful! (333 reviews) Friendly staff, nice room Reviewed on Mar 3, 2026 ![Albergo Etico Roma](https://images.trvl-media.com/lodging/34000000/33130000/33120500/33120475/0a76f398_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Albergo Etico Roma Flaminio Save 100% on your flight $1,471 per person May 10 - May 16 found 10 hours ago Roundtrip flight included New York (JFK) to Rome (FCO) 9.6/10 Exceptional! (353 reviews) The staff was so nice! The morning breakfast is amazing! This is a great North Rome spot, fairly close to several key areas to include the Spanish stairs. Lots of locals eat here and it's not as touristy as some of the spots in center square. We took the limo service back and forth to the airport, which was really nice. Reviewed on Feb 21, 2026 ![Exe International Palace](https://images.trvl-media.com/lodging/1000000/930000/922000/921974/6e7c9a2c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Exe International Palace Rome City Centre Save 100% on your flight $1,449 per person Apr 27 - May 4 found 1 day ago Roundtrip flight included New York (NYC) to Rome (FCO) 7.8/10 Good! (1,002 reviews) Very nice ,clean, and friendly hotel. Reviewed on Feb 3, 2026 ![TB Place Roma](https://images.trvl-media.com/lodging/97000000/96010000/96006400/96006388/541340bd_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### TB Place Roma Rome City Centre Save 100% on your flight $2,416 per person May 10 - May 16 found 1 day ago Roundtrip flight included New York (JFK) to Rome (FCO) 9.4/10 Exceptional! (53 reviews) Fantastic hotel, nice rooms, very helpful staff and a central but quiet location. Reviewed on Feb 22, 2026 ![Hotel Splendide Royal - The Leading Hotels of the World](https://images.trvl-media.com/lodging/1000000/590000/581100/581053/263507da_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Splendide Royal - The Leading Hotels of the World Rome City Centre Save 100% on your flight $3,532 per person May 17 - May 22 found 12 hours ago Roundtrip flight included New York (JFK) to Rome (FCO) 9.4/10 Exceptional! (1,000 reviews) Fantastic, beautiful . Reviewed on Feb 28, 2026 ## Where to stay in Ostiense Find the best Ostiense areas and neighborhoods for the activities you enjoy most. [Learn more about Ostiense](https://expedia.com/Rome-Ostiense.dx6227596) ![Via del Corso which includes heritage architecture, heritage elements and street scenes](https://images.trvl-media.com/place/6147046/23c2bc21-bb33-4778-b64d-bbfa58503b1c.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome City Centre 8 out of top 10 points of interest in this area 4.5/5(3,994 area reviews) Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago. [Find hotel + flight trips in Rome City Centre](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Rome%20City%20Centre&DestID=553248633938945217&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Rome Historic Centre showing a statue or sculpture, a fountain and a square or plaza](https://images.trvl-media.com/place/6200441/57c34773-acbf-4b05-b5e7-9b3e692babe1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Rome Historic Centre 5/5(1 area review) Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby. [Find hotel + flight trips in Rome Historic Centre](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Rome%20Historic%20Centre&DestID=6200441&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Trastevere showing street scenes as well as a couple](https://images.trvl-media.com/place/6046256/44314ce1-293d-46c2-8929-fc821edf8fc1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Trastevere 4.5/5(411 area reviews) Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber. [Find hotel + flight trips in Trastevere](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Trastevere&DestID=6046256&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Monti which includes heritage elements, heritage architecture and a ruin](https://images.trvl-media.com/place/6185346/01855336-589e-456f-975e-2734b7e91944.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Monti 4.5/5(1,380 area reviews) Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts. [Find hotel + flight trips in Monti](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Monti&DestID=6185346&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Trevi which includes food and markets](https://images.trvl-media.com/place/553248634717495100/5af85b66-a718-45b6-9792-c4ffe84ee4d6.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Trevi Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station. [Find hotel + flight trips in Trevi](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Trevi&DestID=553248634717495100&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ## Ostiense Hotel Deals ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Quirinale Via Nazionale 7 Rome RM Fully refundableReserve now, pay when you stay $168 nightly $202 total Mar 8 - Mar 9 Total with taxes and fees 8.6/10 Excellent! (1,950 reviews) Clean and quite room. The staff is always helpful. Reviewed on Mar 6, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F8%2F2026&endDate=3%2F9%2F2026&selected=1058&PinnedHotelID=1058&HadPinnedHotel=true®ionId=6227596) ![Ruby Giulia Hotel Rome](https://images.trvl-media.com/lodging/115000000/114940000/114933100/114933055/960b9e99_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ruby Giulia Hotel Rome Via Agostino Depretis 45 Rome RM Fully refundableReserve now, pay when you stay $197 nightly $231 total Mar 11 - Mar 12 Total with taxes and fees 9.8/10 Exceptional! (38 reviews) Modern clean rooms, good locations. Staff are great! Reviewed on Mar 3, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F11%2F2026&endDate=3%2F12%2F2026&selected=114933055&PinnedHotelID=114933055&HadPinnedHotel=true®ionId=6227596) ![Hotel Nazionale](https://images.trvl-media.com/lodging/1000000/30000/26800/26756/f62b396f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Nazionale Piazza Montecitorio, 131 Rome RM $217 nightly $256 total Mar 15 - Mar 16 Total with taxes and fees 9.6/10 Exceptional! (1,013 reviews) I enjoyed my stay at Reviewed on Mar 5, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&selected=26756&PinnedHotelID=26756&HadPinnedHotel=true®ionId=6227596) [See all 16,255 properties in Ostiense](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F8%2F2026&endDate=3%2F9%2F2026®ionId=6227596) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ### Discover the most popular places to visit in Ostiense ![Light in the Basilica of St Paul](https://images.trvl-media.com/place/6074140/81bfbca8-0a41-458b-9fb8-ef83ef529db6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Basilica of St. Paul Outside the Walls You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area. [](https://expedia.com/Basilica-Of-St-Paul-Outside-The-Walls-Ostiense.d6074140.Vacation-Attraction) #### Eataly Roma You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area. [](https://expedia.com/Eataly-Roma-Ostiense.d553248621563230352.Vacation-Attraction) #### Roma Tre University Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area. [](https://expedia.com/Roma-Tre-University-Ostiense.d6147114.Vacation-Attraction) ### Things to do ![Rome Hop-On Hop-Off Big Bus Tour](https://mediaim.expedia.com/localexpert/376190/27f7cb2b-8299-411e-bfc9-45c2f55e37d8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus $36 per adult **84%** of travellers recommend [](https://expedia.com/things-to-do/rome-big-bus-hop-on.a376190.activity-details) ![Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour](https://mediaim.expedia.com/localexpert/3138351/00713dcf-a749-4990-815b-c1abc113d09f.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour $82 per adult **84%** of travellers recommend [](https://expedia.com/things-to-do/rome-colosseum-with-arena.a3138351.activity-details) ![Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica](https://mediaim.expedia.com/localexpert/1008396/d1b7fce5-e5c4-48ff-9148-df750d6ee6ce.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica $29 per adult **90%** of travellers recommend [](https://expedia.com/things-to-do/skip-the-line-group-tour-of-the-vatican.a1008396.activity-details) [See all activities in Rome](https://expedia.com/things-to-do/search?rid=6227596) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.