Ostiense Vacations from $1,031

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Eurostars Roma Aeterna

Eurostars Roma Aeterna

4 out of 5
Municipio VII
Save 100% on your flight
Price was $1,805, price is now $1,031 per person
$1,031
per person
May 5 - May 11
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
8.2/10 Very Good! (1,001 reviews)
Good Service, nice staff, I want recommend it 100% ti others. Nice hotel as well. We were happy there. Thank you for everything.

Reviewed on Feb 16, 2026

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $2,556, price is now $1,151 per person
$1,151
per person
Apr 27 - May 3
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Courteous and helpful staff. Clean, great amenities

Reviewed on Feb 8, 2026

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,541, price is now $1,421 per person
$1,421
per person
Apr 2 - Apr 7
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Very pleasant staff. Room clean and spacious. Nice and central for shopping, restaurants, sightseeing etc.

Reviewed on Feb 10, 2026

Exe International Palace

Exe International Palace

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,264, price is now $1,296 per person
$1,296
per person
Apr 26 - May 2
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
7.8/10 Good! (1,002 reviews)
Very nice ,clean, and friendly hotel.

Reviewed on Feb 3, 2026

U-Visionary Roma Hotel

U-Visionary Roma Hotel

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $4,127, price is now $2,491 per person
$2,491
per person
May 9 - May 15
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Rome (FCO)
9.6/10 Exceptional! (411 reviews)
I was so disappointed with this hotel. It purports to be a 5 star hotel and I was certainly paying a rate commensurate with that but it simply isn’t of a high enough standard to deserve a 5 star rating. From staff arguing with each other in front of us to being denied entry to the bar because it was too busy; there simply isn’t enough room for me to list their faults here, which essentially come down to a lack of attention to detail and care but if the management want to write to me I will give them the full list.

Reviewed on Jan 3, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $188 total per night from Feb 22 to Feb 23
$188 total
Feb 22 - Feb 23
Total with taxes and fees
8.6/10 Excellent! (1,937 reviews)
Na

Reviewed on Feb 16, 2026

Hotel Quirinale
Hotel Nazionale

Hotel Nazionale

4 out of 5
Piazza Montecitorio, 131 Rome RM
$188 nightly
The price is $224 total per night from Feb 22 to Feb 23
$224 total
Feb 22 - Feb 23
Total with taxes and fees
9.6/10 Exceptional! (1,009 reviews)
This hotel was a gem. The location was perfect, the staff was friendly and helpful, and our room was large and spotless. Great experience!

Reviewed on Feb 16, 2026

Hotel Nazionale
Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

4 out of 5
Via Emilio Morosini 27 Rome RM
Fully refundableReserve now, pay when you stay
$166 nightly
The price is $200 total per night from Feb 24 to Feb 25
$200 total
Feb 24 - Feb 25
Total with taxes and fees
9.4/10 Exceptional! (1,210 reviews)
Everything was great. Staff were wonderful. Breakfast was excellent. No complaints.

Reviewed on Feb 15, 2026

Trastevere Roma | UNA Esperienze
See all 16,129 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Light in the Basilica of St Paul

Basilica of St. Paul Outside the Walls

4.5/5(352 reviews)

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$55
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$89
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.