Ostiense Vacations from $1,058

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

Nomentano
Save 100% on your flight
$1,058
per person
Nov 25 - Dec 1
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (327 reviews)
The room was very clean and the staff was friendly and very helpful. I had very low expectations for the included breakfast but it was fantastic. Homemade baked goods every morning, breakfast sandwiches, scrambled eggs, bacon, fruit, different types of breads, cereal. We were always offered a cappuccino. It was great. It's a bit of a walk from the city center but it's very doable and the public transit system is great. I will stay here again the next time I'm in Rome.

Reviewed on Oct 19, 2026

Hotel Maximus

Hotel Maximus

Rome City Centre
Save 100% on your flight
$1,471
per person
Nov 26 - Dec 1
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (69 reviews)
Great renovation of the facilities. Lovely room with private patio. Very well laid out and provisioned. Front desk staff was very helpful and friendly, anticipating needs and offering great help and suggestions. Cleaning staff and room service were exceptional - great service. You can tell when a facility is run well and the staff are happy and motivated - this was a wonderful stay in our visit to Rome. Location was great - near the Opera and great restaurants, walkable to Trevi, Pantheon, and Borghese. Thanks for a great time at your hotel!

Reviewed on Oct 20, 2026

Hotel Le Petit

Hotel Le Petit

Rome City Centre
$1,251
per person
Nov 24 - Nov 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (26 reviews)
Staff was very helpful. Rooms were very very small. Elevator is very crammed. Breakfast was very good. Good hotel for the money.

Reviewed on Oct 23, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$1,681
per person
Dec 11 - Dec 16
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)
The hotel is beautifully appointed. The staff was friendly and helpful. As an example, after we we said that the pillows were too hard, the hotel quickly delivered softer pillows to our room. The area in which the hotel is located also includes several execellent dining options. Our stay was very pleasant. I would stay there again if I returned to Rome.

Reviewed on Oct 23, 2026

U-Visionary Roma Hotel

U-Visionary Roma Hotel

Rome City Centre
Save 100% on your flight
$1,851
per person
Nov 24 - Nov 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (522 reviews)
Staff was incredible and helped us celebrate our 35th Anniversary. Location is exceptional and near many top Rome attractions . Breakfast was delicious and plentiful. Highly recommend this hotel!

Reviewed on Oct 20, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

Find hotels in Monti
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

Find hotels in Trastevere
A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Find hotels in Trevi

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$100 nightly
$127 total
Nov 9 - Nov 10
Total with taxes and fees
9.2/10 Wonderful! (504 reviews)
"Es un lugar muy accesible"

Reviewed on Oct 21, 2026

Aparthotel Colombo Roma
Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$70 nightly
$84 total
Oct 24 - Oct 25
Total with taxes and fees
Fabulous Village
Hotel Quirinale

Hotel Quirinale

Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$175 nightly
$210 total
Nov 15 - Nov 16
Total with taxes and fees
8.8/10 Excellent! (1,942 reviews)
"The room was prefect for 2 of us. We had limited hot water, but it didn’t greatly affect us. The staff was friendly and helpful. The breakfast was good and had many selections. Close enough to train station that we could walk with luggage, but yet not too close to where we felt unsafe. It was a 15 ..."

Reviewed on Oct 23, 2026

Hotel Quirinale
See all 16,620 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Ostiense attractions

Basilica of St. Paul Outside the Walls

9.0/10 (762 reviews)
You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.
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Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Art Center Acea

6.0/10 (1 review)
Enjoy an outing to Art Center Acea during your stay in Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.
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Luneur Park

8.0/10 (2 reviews)
Bring the kids to Luneur Park and have a fun-filled day at this amusement park in Rome. While in the area, you can find time to visit its cathedral.
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Tre Fontane Stadium

Catch an event at Tre Fontane Stadium during your trip to Rome. While in the area, you can find time to visit its cathedral.
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Montemartini Museum

8.0/10 (1 review)
You can study the exhibits at Montemartini Museum, a museum with a story of its own, during your travels to Rome. Visit the notable monuments and stunning cathedral in this vibrant area.
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Casa del Jazz

You can enjoy a show at Casa del Jazz during your stay in Rome.
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Goa Club

Goa Club is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? While in the area, you can find time to visit its cathedral.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$26
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$127
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$53
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.