Ostiense Vacations from $857

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Save 100% on your flight
Price was $1,527, price is now $857 per person
$857
per person
Apr 2 - Apr 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Excelente lugar en una area muy tranquila y cerca de lugares para ir a comer o cenar, su personal muy amable elvis, Diego todo si personal .🙏🙏🙏

Reviewed on Jan 17, 2026

Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Save 100% on your flight
Price was $1,416, price is now $910 per person
$910
per person
Mar 13 - Mar 17
found 24 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (335 reviews)
Wonderful stay, would be back

Reviewed on Dec 16, 2025

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,086, price is now $1,152 per person
$1,152
per person
Mar 26 - Mar 31
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Couldn't ask for a better location! Delicious breakfast, beautiful room and friendly staff.

Reviewed on Jan 19, 2026

Hassler Roma

Hassler Roma

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $7,442, price is now $4,833 per person
$4,833
per person
Mar 29 - Apr 4
found 13 hours ago
Roundtrip flight included
Los Angeles (LAX) to Rome (FCO)
9.6/10 Exceptional! (154 reviews)
Everything was perfect. Thank you Giorgio and everyone at Hassler Roma for a memorable experience.

Reviewed on Jan 5, 2026

Smart Guesthouse

Smart Guesthouse

3 out of 5
Rome City Centre
Price was $1,881, price is now $1,256 per person
$1,256
per person
Apr 4 - Apr 10
found 21 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.6/10 Exceptional! (76 reviews)
Great location because of how close it is to the train station, stay was very pleasant. The hotel was super communicative. Would recommend!

Reviewed on Nov 19, 2025

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

4 out of 5
Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $84 total per night from Feb 4 to Feb 5
$84 total
Feb 4 - Feb 5
Total with taxes and fees
9/10 Wonderful! (361 reviews)
The staff were so kind and helpful. I loved the fact that tours were included in the stay. The hotel is near the major bus lines to get to tourist attractions.

Reviewed on Jan 15, 2026

Aparthotel Colombo Roma
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $159 total per night from Jan 25 to Jan 26
$159 total
Jan 25 - Jan 26
Total with taxes and fees
8.6/10 Excellent! (1,927 reviews)
We had a great 3 night stay, great location, very nice breakfast buffet, nice large, clean room. Front desk staff were friendly and very helpful. Thank you!

Reviewed on Jan 16, 2026

Hotel Quirinale
Hotel Artemide

Hotel Artemide

4 out of 5
Via Nazionale 22 Rome RM
Fully refundableReserve now, pay when you stay
$148 nightly
The price is $181 total per night from Feb 5 to Feb 6
$181 total
Feb 5 - Feb 6
Total with taxes and fees
9.6/10 Exceptional! (1,006 reviews)
Room was in good condition, staff were attentive. View wasn’t really nice as we were overlooking the air conditioning units but at least it wasn’t the busy main road. Roof top bar was very good and the bar manager was very entertaining.

Reviewed on Jan 19, 2026

Hotel Artemide
See all 15,388 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
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Kid Friendly Vacations
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Discover the most popular places to visit in Ostiense

Light in the Basilica of St Paul

Basilica of St. Paul Outside the Walls

4.5/5(352 reviews)

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$55
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$29
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.