Ostiense Vacations from $852

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Price was $1,988, price is now $852 per person
$852
per person
Apr 7 - Apr 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
7.4/10 Good! (1,026 reviews)
Yes all was really well organised

Reviewed on Feb 19, 2026

C10 Boutique Hotel

C10 Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,723, price is now $1,095 per person
$1,095
per person
Apr 26 - May 2
found 1 day ago
Roundtrip flight included
New York (NYC) to Rome (FCO)
7.6/10 Good! (19 reviews)
Thank you - we had a very enjoyable stay!

Reviewed on Dec 29, 2025

Rhinoceros

Rhinoceros

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,403, price is now $2,176 per person
$2,176
per person
Apr 25 - May 2
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9/10 Wonderful! (29 reviews)
Where to start. Everything. Everything. The hosts are very special. An uncommon concierge. A friend. The whole team. Day and night. The beautiful gallery. I would rather keep it my and my wife’s special secret. You will have to stay at Rhinoceros to discover this treasure. My complements to the Fendi's.

Reviewed on Dec 30, 2025

Hotel Celio

Hotel Celio

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,878, price is now $1,298 per person
$1,298
per person
Apr 25 - May 2
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8.6/10 Excellent! (174 reviews)
Beautiful place to stay were very helpful and breakfast was great thank you for your kindness

Reviewed on Oct 8, 2025

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $2,149, price is now $918 per person
$918
per person
Apr 7 - Apr 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Courteous and helpful staff. Clean, great amenities

Reviewed on Feb 8, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $187 total per night from Feb 22 to Feb 23
$187 total
Feb 22 - Feb 23
Total with taxes and fees
8.6/10 Excellent! (1,938 reviews)
Room was elegant and comfortable. Staff was helpful and courteous. Nice stay!

Reviewed on Feb 11, 2026

Hotel Quirinale
Hotel Nazionale

Hotel Nazionale

4 out of 5
Piazza Montecitorio, 131 Rome RM
$193 nightly
The price is $230 total per night from Feb 25 to Feb 26
$230 total
Feb 25 - Feb 26
Total with taxes and fees
9.4/10 Exceptional! (1,006 reviews)
This hotel was a gem. The location was perfect, the staff was friendly and helpful, and our room was large and spotless. Great experience!

Reviewed on Feb 16, 2026

Hotel Nazionale
Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

4 out of 5
Via Emilio Morosini 27 Rome RM
Fully refundableReserve now, pay when you stay
$150 nightly
The price is $182 total per night from Feb 23 to Feb 24
$182 total
Feb 23 - Feb 24
Total with taxes and fees
9.4/10 Exceptional! (1,209 reviews)
Great experience and location

Reviewed on Feb 14, 2026

Trastevere Roma | UNA Esperienze
See all 16,222 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Light in the Basilica of St Paul

Basilica of St. Paul Outside the Walls

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$89
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Underground Rome Catacombs Tour with Aqueducts & Appian Way

Underground Rome Catacombs Tour with Aqueducts & Appian Way

$64
per adult
94% of travellers recommend
Underground Rome Catacombs Tour with Aqueducts & Appian Way
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$55
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.