Ostiense Vacations from $803

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Save 100% on your flight
Price was $1,280, price is now $803 per person
$803
per person
Feb 27 - Mar 4
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (335 reviews)
Wonderful stay, would be back

Reviewed on Dec 16, 2025

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,411, price is now $1,284 per person
$1,284
per person
Apr 15 - Apr 20
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Couldn't ask for a better location! Delicious breakfast, beautiful room and friendly staff.

Reviewed on Jan 19, 2026

Hotel Varese Roma

Hotel Varese Roma

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,260, price is now $816 per person
$816
per person
Apr 15 - Apr 20
found 18 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
8.6/10 Excellent! (342 reviews)
Room clean with complete amenities. Close to Termini. Breakfast was great. Nice staff.

Reviewed on Jan 4, 2026

EXE Domus Aurea

EXE Domus Aurea

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,790, price is now $1,162 per person
$1,162
per person
Apr 9 - Apr 15
found 14 hours ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
8/10 Very Good! (490 reviews)
Everything was great. The check in process was fast. Enjoyed breakfast specially it was located on the rooftop. The room was always clean. Friendly and helpful staffs.

Reviewed on Dec 31, 2025

Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Price was $2,027, price is now $1,325 per person
$1,325
per person
Apr 19 - Apr 25
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.4/10 Good! (1,026 reviews)
Clean room, friendly and helpful staff and the free beeakfast!

Reviewed on Jan 25, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

4 out of 5
Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $90 total per night from Feb 11 to Feb 12
$90 total
Feb 11 - Feb 12
Total with taxes and fees
9/10 Wonderful! (363 reviews)
The staff were so kind and helpful. I loved the fact that tours were included in the stay. The hotel is near the major bus lines to get to tourist attractions.

Reviewed on Jan 15, 2026

Aparthotel Colombo Roma
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $174 total per night from Feb 8 to Feb 9
$174 total
Feb 8 - Feb 9
Total with taxes and fees
8.6/10 Excellent! (1,921 reviews)
Clean , old fashion , great location. Highly recommend this property to all. Beautiful !!

Reviewed on Jan 21, 2026

Hotel Quirinale
Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

4 out of 5
Via Emilio Morosini 27 Rome RM
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $195 total per night from Feb 3 to Feb 4
$195 total
Feb 3 - Feb 4
Total with taxes and fees
9.4/10 Exceptional! (1,198 reviews)
Beautiful room, very nice bathroom, everything spotless, and very nicely decorated. Check-in and checkout were smooth. Breakfast was great. Also, very well-located with lots of good restaurants within a few minutes walk.

Reviewed on Jan 21, 2026

Trastevere Roma | UNA Esperienze
See all 16,054 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Light in the Basilica of St Paul

Basilica of St. Paul Outside the Walls

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$55
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$29
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.