Ostiense Vacations from $1,408

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
$1,408
per person
Sep 29 - Oct 1
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
No reviews
Hotel Delle Civette

Hotel Delle Civette

Nomentano
$1,408
per person
Oct 26 - Oct 31
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (316 reviews)
Staff goes above and beyond to help guests. Every single aspect of the hotel was excellent. We plan to stay there again.

Reviewed on Aug 16, 2026

Corinthia Rome

Corinthia Rome

Rome City Centre
Save 100% on your flight
$3,203
per person
Nov 3 - Nov 9
found 22 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
10/10 Exceptional! (1 review)
Best hotel we ever stayed in. Impeccable service. The hotel is brand new. Rooms are spacious and have every amenity you can wish for. Rooms are cleaned twice a day. Great bar and restaurant. We highly recommend the Corinthia Rome

Reviewed on May 17, 2026

Vibe Nazionale

Vibe Nazionale

Rome City Centre
Save 100% on your flight
$1,442
per person
Oct 13 - Oct 18
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8.4/10 Very Good! (118 reviews)
ROMEO Roma

ROMEO Roma

Rome City Centre
Save 100% on your flight
$5,552
per person
Oct 4 - Oct 10
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
10/10 Exceptional! (1 review)
Glorious property, 3-Star food, 5-star service.

Reviewed on May 23, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

Find hotels in Monti
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

Find hotels in Trastevere
A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Find hotels in Trevi

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$52 nightly
$74 total
Aug 26 - Aug 27
Total with taxes and fees
9.2/10 Wonderful! (467 reviews)
"La buanderie n'était pas fonctionnelle, il n'y avait pas de plaque chauffante n'y d'instruments de cuisine tel que sur les photos et l'air climatisé manquait de puissance un peu, mais tout le reste était super. Nous y retournerons certainement."

Reviewed on Aug 24, 2026

Aparthotel Colombo Roma
Hotel Quirinale

Hotel Quirinale

Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$183 nightly
$218 total
Aug 25 - Aug 26
Total with taxes and fees
8.8/10 Excellent! (1,937 reviews)
"Opera"

Reviewed on Aug 22, 2026

Hotel Quirinale
Hilton Rome Airport

Hilton Rome Airport

Via Arturo Ferrarin 2 Fiumicino RM
$244 nightly
$279 total
Aug 27 - Aug 28
Total with taxes and fees
8.4/10 Very Good! (3,354 reviews)
"Stay was good"

Reviewed on Aug 24, 2026

Hilton Rome Airport
See all 16,757 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Ostiense attractions

Basilica of St. Paul Outside the Walls

9.0/10 (762 reviews)
You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the stunning cathedral and notable monuments in this vibrant area.
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Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Art Center Acea

6.0/10 (1 review)
Enjoy an outing to Art Center Acea during your stay in Rome. Experience the fascinating museums and acclaimed theater scene in this vibrant area.
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Luneur Park

8.0/10 (2 reviews)
Bring the kids to Luneur Park and have a fun-filled day at this amusement park in Rome. While in the area, you can find time to visit its cathedral.
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Tre Fontane Stadium

Catch an event at Tre Fontane Stadium during your trip to Rome. While in the area, you can find time to visit its cathedral.
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Montemartini Museum

8.0/10 (1 review)
You can study the exhibits at Montemartini Museum, a museum with a story of its own, during your travels to Rome. Visit the stunning cathedral and notable monuments in this vibrant area.
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ACEA Heritage

You can enjoy some culture when you stop by ACEA Heritage in Rome. While in the area, you can find time to visit its cathedral.
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Goa Club

Goa Club is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? While in the area, you can find time to visit its cathedral.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$26
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome in 1 Day: Vatican & Colosseum Guided Tour – Choose Your Option

Rome in 1 Day: Vatican & Colosseum Guided Tour – Choose Your Option

$200
per adult
86% of travellers recommend
Rome in 1 Day: Vatican & Colosseum Guided Tour – Choose Your Option
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

$207
per adult
96% of travellers recommend
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.