Ostiense Vacations from $681

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Save 100% on your flight
Price was $1,187, price is now $681 per person
$681
per person
Jan 23 - Jan 28
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
19.2/10 Exceptional! (267 reviews)
We just left Rome and our Hotel was in very nice neighborhood close to Metro line B Bologna which is 9 min walk from hotel to connect us to city center. Beds were very comfortable we had 3 twin bed room with 2 long closets for all three of our clothes nice medium size bathroom and staff at front desk GREAT CREW

Reviewed on Nov 7, 2025

Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Save 100% on your flight
Price was $1,870, price is now $1,000 per person
$1,000
per person
Feb 11 - Feb 16
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Rome (FCO)
19.2/10 Exceptional! (335 reviews)
Chambre très bien équipée et petit déjeuner parfait. Calme et propreté

Reviewed on Nov 14, 2025

Elizabeth Unique Hotel

Elizabeth Unique Hotel

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,060, price is now $1,256 per person
$1,256
per person
Feb 2 - Feb 8
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
19.2/10 Exceptional! (243 reviews)
Very clean and well appointed rooms, fantastic professional staff, superb food.

Reviewed on Nov 9, 2025

Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,605, price is now $1,636 per person
$1,636
per person
Feb 2 - Feb 8
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
18/10 Exceptional! (490 reviews)
Not only are the rooms beautifully appointed, the food so delicious, a heavenly harp playing at brunch, the staff with impeccable, customer, service, and professionalism, everything about this hotel screams Luxury and comfort! I will definitely be back!

Reviewed on Nov 12, 2025

Grand Hotel Plaza

Grand Hotel Plaza

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,117, price is now $1,358 per person
$1,358
per person
Feb 2 - Feb 8
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
14.4/10 Exceptional! (1,000 reviews)
Excelente ubicación; staff amable y habitaciones amplias.

Reviewed on Oct 26, 2025

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels.
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Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

9 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Napoleon Hotel

Napoleon Hotel

4 out of 5
Piazza Vittorio Emanuele II 105 Rome RM
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $158 total per night from Dec 10 to Dec 11
$158 total
Dec 10 - Dec 11
Total with taxes and fees
8.4/10 Very Good! (1,004 reviews)
Lovely stay ay th Napoleon hotel. All staff were very welcoming, room was a very good size, breakfast had a great choice and it was an all round great stay. Would definitely stay again.

Reviewed on Nov 18, 2025

Napoleon Hotel
Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $169 total per night from Dec 15 to Dec 16
$169 total
Dec 15 - Dec 16
Total with taxes and fees
8.6/10 Excellent! (1,913 reviews)
This hotel exudes yesteryear charm. We were so happy with our huge room and gorgeous balcony overlooking the central courtyard garden. Its location was perfect for us: close to all the historical sites and a simple walk to Rome Termini. We dined in the restaurant several nights and the food and service ...

Reviewed on Nov 19, 2025

Hotel Quirinale
The Hive Hotel

The Hive Hotel

4 out of 5
Via Torino 6 Rome RM
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $126 total per night from Nov 23 to Nov 24
$126 total
Nov 23 - Nov 24
Total with taxes and fees
9/10 Wonderful! (1,676 reviews)
The costumer service was not professional and the kettle didn't work.

Reviewed on Nov 18, 2025

The Hive Hotel
See all 15,862 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Ostiense

Basilica of St. Paul Outside the Walls

Basilica of St. Paul Outside the Walls

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the notable monuments and churches in this vibrant area.

Basilica of St. Paul Outside the Walls
#GoodEats “Bucatini all’Amatriciana” 😋🤤 Taste of home ❤️

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the acclaimed theater scene and fascinating museums in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the notable monuments and stunning cathedral in this vibrant area.

Roma Tre University

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$51
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
82% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$40
per adult
88% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.