Ostiense Vacations from $822

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Grand Hotel Olympic

Grand Hotel Olympic

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,361, price is now $822 per person
$822
per person
Mar 20 - Mar 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.4/10 Good! (1,026 reviews)
The showers did not drain well and the walls were thin.

Reviewed on Dec 28, 2025

JC Hotel

JC Hotel

4 out of 5
Fonte Ostiense
Save 100% on your flight
Price was $1,591, price is now $885 per person
$885
per person
Mar 21 - Mar 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
8/10 Very Good! (133 reviews)
Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,996, price is now $1,164 per person
$1,164
per person
Mar 25 - Mar 29
found 4 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Clean room friendly staff

Reviewed on Dec 12, 2025

Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Save 100% on your flight
Price was $1,464, price is now $875 per person
$875
per person
Mar 22 - Mar 27
found 2 days ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Breakfast was fresh and healthy each morning. All of the staff were extremely nice and helpful. Loved my stay here, would stay here again and will recommend to friends.

Reviewed on Dec 28, 2025

Exe International Palace

Exe International Palace

4 out of 5
Rome City Centre
Save 100% on your flight
Price was $1,541, price is now $940 per person
$940
per person
Mar 20 - Mar 26
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
7.8/10 Good! (1,002 reviews)
Rooms are tight, old building has not been upgraded. No AC.

Reviewed on Dec 7, 2025

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

9 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Aparthotel Colombo Roma

Aparthotel Colombo Roma

4 out of 5
Via Cristoforo Colombo 112 Rome RM
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $92 total per night from Jan 18 to Jan 19
$92 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
9/10 Wonderful! (350 reviews)
room was clean and cozy, staff was helpful and friendly. 10/10 recommend

Reviewed on Dec 15, 2025

Aparthotel Colombo Roma
Hotel Dei Mellini

Hotel Dei Mellini

4 out of 5
Via Muzio Clementi 81 Rome RM
Fully refundableReserve now, pay when you stay
$239 nightly
The price is $280 total per night from Jan 27 to Jan 28
$280 total
Jan 27 - Jan 28, 2026
Total with taxes and fees
9.2/10 Wonderful! (983 reviews)
Staff is courteous and helpful, the rooms are cleaned daily, breakfast has many choices and the hotel is located in an excellent location.

Reviewed on Dec 26, 2025

Hotel Dei Mellini
The Hive Hotel

The Hive Hotel

4 out of 5
Via Torino 6 Rome RM
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $136 total per night from Jan 13 to Jan 14
$136 total
Jan 13 - Jan 14, 2026
Total with taxes and fees
9/10 Wonderful! (1,725 reviews)
El hotel y sus instalaciones excepcionales! Lo único regular es la atención al cliente tanto en el restaurante como en el lobby

Reviewed on Dec 24, 2025

The Hive Hotel
See all 15,997 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ostiense

Basilica of St. Paul Outside the Walls

Basilica of St. Paul Outside the Walls

4.5/5(352 reviews)

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls
#GoodEats “Bucatini all’Amatriciana” 😋🤤 Taste of home ❤️

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$31
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$36
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$27
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.