Ostiense Vacations from $1,413

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Your Ostiense Vacation

Book a customized vacation package to Ostiense and get ready to experience its nightlife, bars and pubs and culture. However you want to spend your getaway in this food-lovers neighborhood, there are plenty of opportunities to mix relaxation and fun. Your trip to Ostiense wouldn't be complete without a visit to top attractions nearby such as Roman Forum, Pantheon and Piazza Navona. Whatever your travel plans or the size of your budget, booking your dream Ostiense vacation has never been easier with Expedia.

The Latest Ostiense Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Save 100% on your flight
Price was $2,955, price is now $1,413 per person
$1,413
per person
May 3 - May 9
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Courteous and helpful staff. Clean, great amenities

Reviewed on Feb 8, 2026

Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Save 100% on your flight
Price was $2,853, price is now $1,492 per person
$1,492
per person
May 10 - May 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.6/10 Exceptional! (335 reviews)
The staff was so nice! The morning breakfast is amazing! This is a great North Rome spot, fairly close to several key areas to include the Spanish stairs. Lots of locals eat here and it's not as touristy as some of the spots in center square. We took the limo service back and forth to the airport, which was really nice.

Reviewed on Feb 21, 2026

Charme Spagna Boutique Hotel

Charme Spagna Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,601, price is now $1,950 per person
$1,950
per person
May 10 - May 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.2/10 Wonderful! (208 reviews)
Very clean, very helpful staff

Reviewed on Jan 27, 2026

Tree Charme Parliament Boutique Hotel

Tree Charme Parliament Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,250, price is now $1,923 per person
$1,923
per person
May 10 - May 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8.8/10 Excellent! (28 reviews)
One of the best hotels I’ve ever stayed at. It’s a newer hotel in Rome. The room was clean, the staff were very helpful, and the cleaning lady was very thorough. I’d definitely stay here again when I return to Rome. Also, the breakfast and service were great!

Reviewed on Dec 3, 2025

Palazzo Dama

Palazzo Dama

5 out of 5
Rome City Centre
Save 100% on your flight
Price was $3,860, price is now $2,377 per person
$2,377
per person
May 10 - May 16
found 1 day ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
8.8/10 Excellent! (171 reviews)
Wonderful stay at the Palazzo Dama for my husband’s 40th. We had a junior suite which was a good size, very comfortable and immaculate. Great location and friendly, professional staff. Lovely to stay in a boutique hotel with such unique features. Felt very luxe!

Reviewed on Feb 15, 2026

Where to stay in Ostiense

Find the best Ostiense areas and neighborhoods for the activities you enjoy most. Learn more about Ostiense
Via del Corso which includes heritage architecture, heritage elements and street scenes

Rome City Centre

8 out of top 10 points of interest in this area
4.5/5(3,994 area reviews)

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre

Ostiense Hotel Deals

Hotel Quirinale

Hotel Quirinale

4 out of 5
Via Nazionale 7 Rome RM
$165 nightly
The price is $199 total per night from Mar 4 to Mar 5
$199 total
Mar 4 - Mar 5
Total with taxes and fees
8.6/10 Excellent! (1,946 reviews)
Good service, close to activities

Reviewed on Feb 22, 2026

Hotel Quirinale
Hotel Nazionale

Hotel Nazionale

4 out of 5
Piazza Montecitorio, 131 Rome RM
$193 nightly
The price is $230 total per night from Feb 25 to Feb 26
$230 total
Feb 25 - Feb 26
Total with taxes and fees
9.6/10 Exceptional! (1,008 reviews)
We had a room for 3 people, our son is 13 and was very comfy on the sofa bed. Room super clean, equipped with lots of extras which was nice. Room was soundproof so great overnight. Excellent location- within 5-10 mins walk of all the main sights. Such lovely staff, really welcoming and helpful. Would ...

Reviewed on Feb 23, 2026

Hotel Nazionale
Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

4 out of 5
Via Emilio Morosini 27 Rome RM
Fully refundableReserve now, pay when you stay
$188 nightly
The price is $225 total per night from Mar 8 to Mar 9
$225 total
Mar 8 - Mar 9
Total with taxes and fees
9.4/10 Exceptional! (1,221 reviews)
Loved everything . Perfect details and excellent customer service.

Reviewed on Feb 23, 2026

Trastevere Roma | UNA Esperienze
See all 16,222 properties in Ostiense
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Ostiense

Light in the Basilica of St Paul

Basilica of St. Paul Outside the Walls

4.5/5(352 reviews)

You can learn about the history of Rome with a visit to Basilica of St. Paul Outside the Walls. Visit the churches and notable monuments in this vibrant area.

Basilica of St. Paul Outside the Walls

Eataly Roma

You can find the perfect gifts to bring home at Eataly Roma during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Eataly Roma

Roma Tre University

Walk around the campus at Roma Tre University during your stay in Rome. Visit the stunning cathedral and notable monuments in this vibrant area.

Roma Tre University

Things to do

Underground Rome Catacombs Tour with Aqueducts & Appian Way

Underground Rome Catacombs Tour with Aqueducts & Appian Way

$64
per adult
94% of travellers recommend
Underground Rome Catacombs Tour with Aqueducts & Appian Way
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$55
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica

$89
per adult
90% of travellers recommend
Skip-the-Line Group Tour of the Vatican, Sistine Chapel & St. Peter's Basilica
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.