Otoque Island Vacations from $966

Book a Hotel + Flight or Car together to unlock savings

Plan, book, travel with confidence
Better together
Save up to $2,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

The Latest Otoque Island vacation packages

Price found within the past 48 hours. Click for updated prices.

Decapolis Hotel Panama City

San Francisco

$966

per person

Oct 7 - Oct 12

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.6/10 Excellent! (1,716 reviews)

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,364

per person

Nov 10 - Nov 16

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.2/10 Wonderful! (1,001 reviews)

Staff was amazing

Reviewed on Sep 6, 2026

Megapolis Hotel Panamá

San Francisco

Save 100% on your flight

$1,108

per person

Oct 7 - Oct 12

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,692 reviews)

Good

Reviewed on Sep 6, 2026

Casa Mallet by Wynwood House

Casco Viejo

Save 100% on your flight

$1,328

per person

Nov 18 - Nov 22

found 1 day ago

Roundtrip flight included

Georgetown (GEO) to Panama City (PTY)

9.8/10 Exceptional! (29 reviews)

Nice apartment ! Clean and great location

Reviewed on Aug 13, 2026

Hyatt Regency Panama City

Bella Vista

$1,226

per person

Oct 17 - Oct 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.6/10 Exceptional! (423 reviews)

The best in Panama

Reviewed on Sep 6, 2026

Don't see what you're looking for?

See all available trips from Columbus to Otoque Island

View all trips

Otoque Island Hotel Deals

Radisson Riviera Panama

Corregimiento de Chame Punta Chame Panamá Oeste

Fully refundable

$125 nightly

$138 total

Sep 28 - Sep 29

Total with taxes and fees

8.6/10 Excellent! (187 reviews)

"It was next to the beach which was important for me with a balcony overlooking the pool and the sea. The breakfast was buffet style with lots of options to choose from and the staff friendly and helpful. It’s a nice place for a getaway and sleep to the sea waves sounds at night."

Reviewed on Aug 29, 2026

Surfside Beachfront Suites by Playa Caracol Resorts

Carr Bejuco-Punta Chame Punta Chame Panamá Oeste

Fully refundableReserve now, pay when you stay

$160 nightly

$176 total

Sep 13 - Sep 14

Total with taxes and fees

Villa Caprichosa

Aquilino de la guardia, Bristol 2314 Taboga

$144 nightly

$158 total

Sep 8 - Sep 9

Total with taxes and fees

9.8/10 Exceptional! (90 reviews)

"Excelente hospedaje. Todo el personal es muy amable y cordial. La comida excelente, todos los días cenamos y todos los platos fueron muy deliciosos. El desayuno es muy bueno. Es un lugar muy tranquilo y muy bueno para descansar de verdad. La dueña es muy amable también"

Reviewed on Aug 25, 2026

See all 276 properties in Otoque Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.