Palmyra Vacations from $429

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Your Palmyra Vacation

Book a Palmyra vacation package and prepare for a fabulous adventure. Known for its rich history and friendly locals, there's plenty to keep you on the move in this lively city. Fill your trip to Palmyra with tours of its leading attractions. First stop? Make a beeline for Gardner House Museum. Expedia is here to help you escape the everyday. Tailor your vacation to Palmyra to suit your travel style, whatever that may be.

The Latest Palmyra vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO

2.5 out of 5
Price was $489, price is now $429 per person
$429
per person
Mar 5 - Mar 8
found 1 hour ago
Roundtrip flight included
Denver (DEN) to Columbia (COU)
6.8/10 (335 reviews)
It was nice and convenient

Reviewed on Jan 12, 2026

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

2.5 out of 5
Price was $598, price is now $526 per person
$526
per person
Apr 8 - Apr 13
found 6 hours ago
Roundtrip non-stop flight included
New York (JFK) to Columbia (COU)
5.6/10 (456 reviews)
We never got service

Reviewed on Nov 23, 2025

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

2.5 out of 5
Price was $590, price is now $521 per person
$521
per person
Apr 8 - Apr 13
found 6 hours ago
Roundtrip non-stop flight included
New York (JFK) to Columbia (COU)
5.6/10 (381 reviews)
The room was decent. The staff was friendly.

Reviewed on Dec 26, 2025

Baymont by Wyndham Kingdom City

Baymont by Wyndham Kingdom City

2 out of 5
Price was $694, price is now $633 per person
$633
per person
Apr 8 - Apr 13
found 6 hours ago
Roundtrip non-stop flight included
New York (JFK) to Columbia (COU)
8.2/10 Very Good! (128 reviews)
Excellent place to stay when flying out of Lambert

Reviewed on Jan 10, 2026

Quality Inn

Quality Inn

2.5 out of 5
Price was $498, price is now $455 per person
$455
per person
Mar 5 - Mar 8
found 1 hour ago
Roundtrip flight included
Denver (DEN) to Columbia (COU)
6.6/10 (327 reviews)
Clean room, basic amenities. The sausage gravy for the biscuits at breakfast was cold and minimal other selections. Ok overall for the price.

Reviewed on Nov 10, 2025

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Discover the most popular places to visit in Palmyra

Gardner House Museum

4.5/5(3 reviews)

You can browse the exhibits at Gardner House Museum, a museum with a storied past, during your trip to Palmyra. Wander the riverfront in this family-friendly area.

Gardner House Museum

Palmyra Hotel Deals

Stoney Creek Inn Quincy

Stoney Creek Inn Quincy

2 out of 5
3809 Broadway St Quincy IL
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $134 total per night from Jan 31 to Feb 1
$134 total
Jan 31 - Feb 1
Total with taxes and fees
8.6/10 Excellent! (1,006 reviews)
The room was great but the personable service from the very attentive staffer at the front desk (and later behind the bar) was above par by a wide margin! I believe he was an assistant manager. If we find ourselves back in town, there's no place else we'd even think about staying. Five stars!

Reviewed on Jan 17, 2026

Stoney Creek Inn Quincy
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

2.5 out of 5
120 Lindsey Drive Hannibal MO
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $86 total per night from Feb 1 to Feb 2
$86 total
Feb 1 - Feb 2
Total with taxes and fees
8/10 Very Good! (1,000 reviews)
Clean and comfortable. Nice hot breakfast. Great staff, very friendly and welcoming.

Reviewed on Jan 15, 2026

Quality Inn & Suites Hannibal West
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

2.5 out of 5
105 Lakeside Dr Hannibal MO
Fully refundable
$98 nightly
The price is $114 total per night from Feb 1 to Feb 2
$114 total
Feb 1 - Feb 2
Total with taxes and fees
9.6/10 Exceptional! (1,004 reviews)
Love that I could bring my cat. This is 4th stay, largely due to the cost of a pet. The hotell is clean and I feel safe. Nice having restaurants so close. Will stay again on my next cross country trip.

Reviewed on Jan 13, 2026

Sleep Inn & Suites Hannibal West
See all 171 properties in Palmyra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Palmyra Vacation Packages

Palmyra Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Quincy Regional-Baldwin Field Airport (UIN)
Population
3,600
Max Temp Winter
35ºF
Max Temp Summer
85ºF

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Frequently asked questions

How much does a Palmyra vacation package cost?
Offering excellent value package deals from $429 on Expedia, you'll be thrilled with how little a vacation to Palmyra costs! Our packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Palmyra?
You can usually find lower rates and greater availability in June, August and December. Explore our cheap Palmyra vacation packages and you could get some great off-season discounts.
How many days is enough for Palmyra?
The ideal length of your Palmyra vacation depends on what you'd like to do and see. Usually, a few days to a week will give you enough time to go to all the main attractions and discover some hidden treasures along the way.
How to find the best Palmyra package deals?
Begin your search for a Palmyra package deal by entering your destination and preferred trip dates under our "Packages" tab. Then apply some filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Palmyra package deal straight away, just change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Palmyra getaway off to a flying start.
Is it cheaper to book a Palmyra vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll generally get a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Palmyra vacation by choosing your preferred type of stay, airline and car class.
When to book a vacation package to Palmyra?
Score incredible discounts by booking your flights ahead of time with Expedia. If spontaneity is more your style, grab one of our last-minute deals for a spur-of-the-moment Palmyra break.
Does Expedia offer Book Now, Pay Later Palmyra vacation packages?
Set off on your dream getaway to Palmyra with our Book Now, Pay Later vacations. No need to save up or hold off until the next payday — we've teamed up with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans let you spread the total cost over 3, 6 or 12 months. With no late payment fees or extra charges, it's easy to budget for your trip and snap up bargains before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.