Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 590,000 properties worldwide.

Search over a million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Panama Canal Zone Independent Hotels

See all 197 Hotels in Panama Canal Zone
Riande Aeropuerto Hotel & Casino
Vía Tocumen, Tocumen
Riande Aeropuerto Hotel & Casino
$91
4.0/5 (1,924 reviews)

Wonderful hotel lovely staff

altText May 9, 2018
 
 
Innfiniti Hotel & Suites
Calle 33 Este a 100 mts de Ave Balboa, Panama City
Innfiniti Hotel & Suites
$58
4.5/5 (13 reviews)
 
 
The Bahia Grand Hotel
Punta Colon Street, Panama City
The Bahia Grand Hotel
$139
3.8/5 (10 reviews)

We had a great time, the restaurant was exceptional and staff very friendly.

altText May 19, 2018
 
 
Las Americas Golden Tower Panama
Av. Balboa con Calle 53, Panama City
Las Americas Golden Tower Panama
$123
4.3/5 (176 reviews)

Really nice views from the room's window. Check-in/Check-out was a breeze and food served on breakfast was delightful.

altText May 21, 2018
 
 
Plaza Paitilla Inn Hotel
Italy Avenue, Punta Paitilla, Panama City
Plaza Paitilla Inn Hotel
$70
3.9/5 (704 reviews)

I chose this hotel for the view but had to change rooms because the view room I had booked apparently was not on the reservation. Once I got sorted out things were fine view wise, although there is fairly thick polarizing film on the windows which made picture taking a bit tricky. The hotel is obviously ...

altText May 19, 2018
 
 
Central Hotel Panama
Plaza de la Independencia Casco Viejo, Panama City
Central Hotel Panama
$129
4.3/5 (112 reviews)

Wonderful Hotel in the Old City (Casco viejo) of Panamá. Nice people, great architecture and a great location. Everything was great. Restaurant isn’t that fabulous. The room has no storage (for clothes) as well as the bathroom. The shower could be better. The pool is too small.

altText May 6, 2018
 
 
Global Hotel Panama
Calle 54 Este y Samuel Lewis, Panama City
Global Hotel Panama
$85
4.6/5 (166 reviews)

Is beautiful place, i like so much your whirepo

altText May 10, 2018
 
 
Hotel Coral Suites
Calle D El Cangrejo, Panama City
Hotel Coral Suites
$57
4.3/5 (427 reviews)

Very nice Hotel, well located. Great kind staff. Good breakfast. Some times at breakfast we had to request that some of the foods should be put back when it finished. The room has a complete kitchen with refrigerator. Nice poll at the last floor.

altText May 22, 2018
 
 
DeVille Hotel Boutique
50 street and Beatriz M. De Cabal, Panama City
DeVille Hotel Boutique
$50
4.2/5 (321 reviews)

Perfect boutique downtown panama city. Excellent location, perfect price. It is "my" boutique downtown panama city.

altText May 18, 2018
 
 
Veneto Hotel & Casino
Eusebio A Morales Ave And Via Veneto Str, Panama City
Veneto Hotel & Casino
$34
3.3/5 (1,407 reviews)

This is a very nice Hotel ,it is close to everything. And for single guys , there are plenty of beautiful women iin the Hotel or outside on the streets.

altText Apr 12, 2018
 
 
Express Inn Panama International Airport Hostel
Calle Enrique Malek, Tocumen
Express Inn Panama International Airport Hostel
$39
2.7/5 (128 reviews)

Very nice and cosy hotel near to the airport , room with air conditioner, clean, hot water, friendly staff.

altText Apr 10, 2018
 
 
The Executive Hotel
Calle 52, Panama City
The Executive Hotel
$55
4.1/5 (90 reviews)
 
 
Albrook Inn
Las Magnolias, Building 14, Panama City
Albrook Inn
$50
3.8/5 (340 reviews)

An oasis in the middle of chaotic Panama City. Beautiful grounds and pools. the setting is not a commercial district, but an old Panama neighborhood of well maintained mansions on a cul de sac. We enjoyed the restaurant, pool, and grounds. The value is excellent.

altText May 7, 2018
 
 
Riande Granada Urban Hotel
El Cangrejo; Calle Eusebio A, Morales, Panama City
Riande Granada Urban Hotel
$63
4.0/5 (409 reviews)

This was my fourth visit to Panama City, and this is definitely my favorite hotel. Perfect location, lovely rooms and view. The pool is quiet and picturesque. The staff is cheerful and accommodating. The biergarten downstairs has fantastic food, a charming atmosphere, and works like a well-oiled ...

altText Mar 27, 2018
 
 
Metro Hotel Panama
Via Veneto, Calle D El Cangrejo, Panama City
Metro Hotel Panama
$35
3.8/5 (299 reviews)

Very good location. I only was 1 night but I liked it.

altText Apr 16, 2018
 
 
The Saba Hotel
Panama Internacional zone,Argentina Ave, Panama City
The Saba Hotel
$52
4.0/5 (249 reviews)

We only stayed one night at the Saba Hotel, but it more than met our needs. First off, it is really modern and artsy, and very appealing. It even smelled really good. A fresh oasis in the middle of the city, especially since there was construction going on in the street outside. We arrived at the ...

altText Apr 10, 2018
 
 
Gamboa Rainforest Resort
Corregimiento de Cristobal, IA 5, Gamboa
Gamboa Rainforest Resort
$119
3.8/5 (259 reviews)

All the choices at the buffet meals were fresh and delicious, the tour desk was most helpful in connecting us with excellent guides for bird watching and boat trips to Monkey Island...the pool was super clean and fun too, loved this place and would love to make a return visit to the Gamboa Rainforest ...

altText May 17, 2018
 
 
Hotel Ojos del Rio
calle 41 este, Panama City
Hotel Ojos del Rio
$46
4.0/5 (284 reviews)

The staff was so helpful and this newer hotel had that boutique feel. The bed was so comfy and it was nice to have a restaurant upstairs. I would definitely stay there again. My daughter and I stayed for 7 days.

altText Feb 19, 2018
 
 
Grand International Hotel
Via Argentina Con Calle José Martí, Panama City
Grand International Hotel
$47
3.5/5 (444 reviews)

We heard loud construction the whole time we where there thankfully we only stayed for two nights.

altText May 20, 2018
 
 
American Trade Hotel
Plaza Herrera Casco Viejo, Panama City
American Trade Hotel
$199
4.6/5 (134 reviews)

We stayed at this hotel For three nights. Great location and the staff was very helpful. We stayed in the Panoramic room. Gorgeous biewa. My only complaint was the loud noise coming from the bar across the street. We heard the loud music from 9pm till 3am every night. Also, the lighting in the bathroom ...

altText May 8, 2018
 
 
Hotel Centroamericano
Avenida Ecuador y Justo Arosemena, Panama City
Hotel Centroamericano
$30
3.7/5 (373 reviews)

it is a clean hotel and nice staff rooms are nice and accommodating in the cfenter of panama city I would recommend this hotel to everyone

altText Apr 6, 2018
 
 
Map

Recently booked Panama Canal Zone hotels

Radisson Summit Hotel and Golf Panama
4.0 out of 5.0
Last booking: 34 hours ago

Independent Panama Canal Zone Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Independent hotels in Panama Canal Zone, Panama. Known for well-appointed rooms and friendly, personalized service, each of the top Independent Panama Canal Zone hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Panama Canal Zone Independent locations may even offer extra little benefits and discounts for frequent travelers.