Panama Vacation Rentals

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Our top choices for Panama vacation rentals

Harrison House; Litchfield, IL; Pets welcome

Litchfield
10.0 out of 10, Exceptional, (15)
"Cozy house, great amenities, and the hosts responded to questions quickly. Definitely will be staying again!"
United States
Jennifer G.
$175 nightly
The price is $185
Jan 3 - Jan 4, 2026
Total with taxes and fees
Harrison House; Litchfield, IL; Pets welcome

Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

Mulberry Grove
9.6 out of 10, Exceptional, (28)
"Perfect place for shinrin-yoku (forest bathing)!"
United States
Lori M.
$197 nightly
The price is $209
Jan 5 - Jan 6, 2026
Total with taxes and fees
Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

Edwards House; Litchfield, IL; Pets welcome

Litchfield
10.0 out of 10, Exceptional, (21)
"Nice stay as our stopover point between Texas and Northern Wisconsin."
United States
Robert N.
$159 nightly
The price is $169
Dec 12 - Dec 13
Total with taxes and fees
Edwards House; Litchfield, IL; Pets welcome

Jackson House; Pets Welcome

Litchfield
10.0 out of 10, Exceptional, (17)
"Good communication, easy process, quiet neighborhood, comfortable house and an overall good value."
United States
Terry R.
$170 nightly
The price is $180
Dec 11 - Dec 12
Total with taxes and fees
Jackson House; Pets Welcome

Route 66 house; Litchfield IL; Pets welcome

Litchfield
9.8 out of 10, Exceptional, (18)
"Nice little place, check in and communication excellent. Perfect for us when visiting my Dad who lives near by."
United States
Mike O.
$159 nightly
The price is $169
Dec 13 - Dec 14
Total with taxes and fees
Route 66 house; Litchfield IL; Pets welcome

State Street House; 3-br house; PETS WELCOME; Litchfield

Litchfield
10.0 out of 10, Exceptional, (14)
"Great location. Wonderful owner"
United States
David E.
$209 nightly
The price is $222
Jan 1 - Jan 2, 2026
Total with taxes and fees
State Street House; 3-br house; PETS WELCOME; Litchfield

New Minglewood is our Cozy 3-bedroom cabin with WiFi, AC in lovely Irving

Irving
10.0 out of 10, Exceptional, (5)
"This was our second time staying here and it didn't dissapoint. "
United States
Kimberly D.
$372 nightly
The price is $394
Dec 11 - Dec 12
Total with taxes and fees
New Minglewood is our Cozy 3-bedroom cabin with WiFi, AC in lovely Irving
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Find out more about Panama

Everything you need to know about Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $169 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama rentals

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Panama?

Yes, there are vacation rentals close to popular points of interest in Panama, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Panama?

State Street House; 3-br house; PETS WELCOME; Litchfield: This vacation home rental near Panama has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings.

What can I see and do in Panama?

While you're exploring the area, Lake Lou Yeager and Walton Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Greenville Country Club and Copper Dock Winery.

What are vacation rentals like in Panama?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Panama. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for family trips or small group gatherings.