Panama Vacation Rentals

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Vacation Rentals in Panama

Jackson House; Pets Welcome

10.0 out of 10, Exceptional, (16)
"Overflow holiday guests stayed at this cute, clean, comfortable home. A wonderful experience with exceptionally kind, engaged, owners! "
$171 nightly
The price is $181
Oct 4 - Oct 5
Total with taxes and fees
Jackson House; Pets Welcome

Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

9.8 out of 10, Exceptional, (26)
"This cabin is so snug and comfortable. It is expertly decorated and furnished so that you only need to bring a change of clothes and you’re set. It was good vibes only. "
$175 nightly
The price is $185
Oct 4 - Oct 5
Total with taxes and fees
Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

Route 66 house; Litchfield IL; Pets welcome

9.8 out of 10, Exceptional, (17)
"Cute little place we were visiting our grandchildren who live in the area and we all had a great time the house is well decorated so cute and everything you need is there. We will check to see if this place is available every time we visit the grandchildren."
$159 nightly
The price is $169
Oct 4 - Oct 5
Total with taxes and fees
Route 66 house; Litchfield IL; Pets welcome

State Street House; 3-br house; PETS WELCOME; Litchfield

10.0 out of 10, Exceptional, (11)
"Great house with a really great layout. Great location for accessing the parts of Litchfield we wanted to find. Super responsive host. "
$209 nightly
The price is $222
Oct 3 - Oct 4
Total with taxes and fees
State Street House; 3-br house; PETS WELCOME; Litchfield

Walk Me Out in the “Morning Dew”. Secluded A-Frame Cabin on Pond with 3 decks

9.6 out of 10, Exceptional, (13)
"Very relaxing fun place to stay!"
$372 nightly
The price is $394
Oct 4 - Oct 5
Total with taxes and fees
Walk Me Out in the “Morning Dew”. Secluded A-Frame Cabin on Pond with 3 decks

Edwards House; Litchfield, IL; Pets welcome

10.0 out of 10, Exceptional, (21)
"Mike and Amy have a beautiful cozy place to stay. My partner and I had a wonderful time and were super comfy during our stay!"
$159 nightly
The price is $169
Oct 3 - Oct 4
Total with taxes and fees
Edwards House; Litchfield, IL; Pets welcome

THE NEST getaways&gatherings, beach/lake sleeps 20+

10.0 out of 10, Exceptional, (38)
"The house was wonderful and the beach a lot of fun. It was the perfect family vacation spot!"
THE NEST getaways&gatherings, beach/lake sleeps 20+

The Aerie- Luxury Lakeside Getaway - Private Beach & Boatdock

10.0 out of 10, Exceptional, (19)
"Plenty of private space, gathering space, eating area and food prep supplies. Lots to do as well. There was even a rainbow over the lake the last day."
The Aerie- Luxury Lakeside Getaway - Private Beach & Boatdock

New Minglewood is our Cozy 3-bedroom cabin with WiFi, AC in lovely Irving

10.0 out of 10, Exceptional, (3)
"This was our second time staying here and it didn't dissapoint. "
$372 nightly
The price is $394
Oct 7 - Oct 8
Total with taxes and fees
New Minglewood is our Cozy 3-bedroom cabin with WiFi, AC in lovely Irving

Lake House off Route 66

9.0 out of 10, Wonderful, (2)
"The home itself was fantastic—clean, well-maintained, and exactly as pictured. The host was responsive and friendly, and the location right on the lake made for a relaxing stay. The only downside, and the reason I’m giving 4 stars instead of 5, is that there’s a camper in the front yard with people staying in it. This wasn’t disclosed in the listing, and it made the experience feel a bit less private and more awkward than expected. If that had been communicated up front, it would’ve helped set...
$204 nightly
The price is $216
Oct 4 - Oct 5
Total with taxes and fees
Lake House off Route 66

Harrison House; Litchfield, IL; Pets welcome

10.0 out of 10, Exceptional, (13)
"Everything was in excellent shape and the fenced yard was great for the pups."
$175 nightly
The price is $185
Oct 19 - Oct 20
Total with taxes and fees
Harrison House; Litchfield, IL; Pets welcome

The Beaumont Retreat

10.0 out of 10, Exceptional, (3)
"Place was great! "
The Beaumont Retreat

Loft Living - Small Town Charm 3-bedroom loft in beautiful Downtown Litchfield

Loft Living - Small Town Charm 3-bedroom loft in beautiful Downtown Litchfield

Chestnut House; Litchfield, IL; Pets Welcome

9.0 out of 10, Wonderful, (7)
"The house was very nice and we had a relaxing stay. We will definitely consider staying here again if we stay in the area."
Chestnut House; Litchfield, IL; Pets Welcome

Charming Hillsboro Home < 1 Mi to Downtown!

2.0 star property
10.0 out of 10, Exceptional, (2)
"Very charming an clean. Locate close to downtown. The host was very responsive to all my questions "
Charming Hillsboro Home < 1 Mi to Downtown!

The Beaumont Suite !

The Beaumont Suite !

Charming Hillsboro Home < 1 Mi to Downtown!

3.0 star property
10.0 out of 10, Exceptional, (1)
"Much nicer then a motel room."
Charming Hillsboro Home < 1 Mi to Downtown!

Home < 3 Mi to Rte 66 & Lake Lou Yaeger!

3.0 star property
Home < 3 Mi to Rte 66 & Lake Lou Yaeger!

Home < 3 Mi to Rte 66 & Lake Lou Yaeger!

Home < 3 Mi to Rte 66 & Lake Lou Yaeger!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Find out more about Panama

Find out more about Panama

Everything you need to know about Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Panama in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $169 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Panama rentals

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Panama?

Yes, there are vacation rentals close to popular points of interest in Panama, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Panama?

Jackson House; Pets Welcome: This vacation home rental near Panama is located on a lake and has a patio, a selection of books, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in Panama?

While you're exploring the area, Lake Lou Yeager and Walton Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Greenville Country Club and Litchfield Museum and Route 66 Welcome Center.

What are vacation rentals like in Panama?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Panama. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for family trips or small group gatherings.