Panama Vacations from $264

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The Latest Panama vacation packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Price was $371, price is now $264 per person
$264
per person
Dec 15 - Dec 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (763 reviews)
Great location! Super friendly staff!

Reviewed on Sep 27, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Save 100% on your flight
Price was $471, price is now $271 per person
$271
per person
Dec 15 - Dec 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,581 reviews)
Love the helpful staff and my room!

Reviewed on Oct 1, 2025

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
Grand Center
Price was $428, price is now $302 per person
$302
per person
Dec 15 - Dec 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (1,005 reviews)
Great hotel will be returning

Reviewed on Sep 30, 2025

Hampton Inn By Hilton St Louis Airport

Hampton Inn By Hilton St Louis Airport

2.5 out of 5
Woodson Terrace
Price was $394, price is now $299 per person
$299
per person
Nov 15 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (62 reviews)
Very nice rxperience

Reviewed on Oct 2, 2025

Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG

3 out of 5
Price was $380, price is now $293 per person
$293
per person
Dec 15 - Dec 18
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (378 reviews)
Issuper nice and very spacious.

Reviewed on Sep 29, 2025

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Panama Hotel Deals

Baymont by Wyndham Litchfield

Baymont by Wyndham Litchfield

2.5 out of 5
1405 W Hudson Dr, Litchfield, IL
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $98 total per night from Oct 3 to Oct 4
$98 total
Oct 3 - Oct 4
Total with taxes and fees
8.2/10 Very Good! (1,018 reviews)
"We were NOT informed about the boil water order. If friends staying at other hotels in Litchfield had not mentioned it, we would never have known. When we asked the person at the desk, his attitude was less than helpful. He offered to give us a CUP of water that had been boiled, but NO bottled water ..."

Reviewed on Sep 30, 2025

Baymont by Wyndham Litchfield
Holiday Inn Express & Suites Litchfield West by IHG

Holiday Inn Express & Suites Litchfield West by IHG

2.5 out of 5
4 Thunderbird Circle, Litchfield, IL
Fully refundable
$134 nightly
The price is $147 total per night from Oct 12 to Oct 13
$147 total
Oct 12 - Oct 13
Total with taxes and fees
9.4/10 Exceptional! (563 reviews)
"Very comfortable, clean hotel. Staff dealt very effectively with a contaminatedwater problem by providing free bottles of water. Established, polite, and very accommodating of any needs"

Reviewed on Sep 30, 2025

Holiday Inn Express & Suites Litchfield West by IHG
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127, Greenville, IL
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $75 total per night from Oct 28 to Oct 29
$75 total
Oct 28 - Oct 29
Total with taxes and fees
7.8/10 Good! (736 reviews)
A good room.
"Could only get warm water temperature in the shower, not hot. This was at 6 pm. The sink faucet cold side would not shut off."

Reviewed on Aug 31, 2025

Super 8 by Wyndham Greenville
See all 36 properties in Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Panama Essential Information

Language
English
Currency
U.S dollars

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Frequently asked questions

How much does a Panama vacation package cost?
Offering great value package deals from $264 on Expedia, you'll be pleasantly surprised at how much a vacation to Panama costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Panama?
You can generally find reduced prices and better availability in November, December and January. Check out our cheap Panama vacation packages and you could score some great off-season deals.
How many days is enough for Panama?
Usually, a handful of days is enough to check out the major attractions during your Panama vacation. However, if you prefer to have some time to kick back or go on day trips, think about extending your trip.
How to find the best Panama package deals?
Use Expedia's filter tool to find some of the best Panama package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your escape for midweek, or search for Panama package deals in the off-peak season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a Panama vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to arranging accommodations and flights individually. Better still, you can customize your Panama getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Panama?
If you have your Panama travel dates locked in, book as soon as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spur-of-the-moment trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Panama vacation packages?
Jet off on your dream getaway to Panama with help from our Book Now, Pay Later vacations. There's no need to save up or wait for payday — we've joined forces with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stay on budget and snag great deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.