Punta Paitilla Vacations from $544

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Your Punta Paitilla Vacation

The easiest way to experience this exciting city is with a tailor-made Punta Paitilla vacation package. Base yourself in the neighborhood of Marbella, which is good for cafes, walking and dining or go someplace else — our package deals are all about you. Every trip to Punta Paitilla needs a well-planned itinerary. Fill yours with attractions like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Expedia will help you escape your daily routine. Tailor your vacation to Punta Paitilla to suit your travel style, whatever that may be.

The Latest Punta Paitilla Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Mahogany Suites

Mahogany Suites

2 out of 5
Price was $825, price is now $544 per person
$544
per person
Feb 20 - Feb 24
found 1 day ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
10/10 Exceptional! (1 review)
Room was spotless, front gate staff was really nice, loved the tiny gym on the main floor.

Reviewed on Dec 21, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,950, price is now $1,046 per person
$1,046
per person
Mar 1 - Mar 6
found 16 hours ago
Roundtrip non-stop flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
What really stood out was the staff at reception – they were outstanding! So friendly, helpful, and attentive from the moment we arrived. They made us feel truly welcome and took care of every little detail. Dining was a highlight too. We ate at the Bistro restaurant, and the food was delicious – creative and flavorful with some unique Panamanian touches. They even provided a sommelier with expert advice on wine selection, who helped us pick the perfect pairings for our meal. It elevated the whole dinner experience! The breakfast buffet was another winner – so many options, from fresh fruits and pastries to local specialties. Everything was fresh and tasty; we looked forward to it every morning.

Reviewed on Dec 25, 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was $1,427, price is now $915 per person
$915
per person
Feb 26 - Mar 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
8.4/10 Very Good! (1,204 reviews)
Breakfast and security top and the the Room was ok

Reviewed on Dec 26, 2025

Amarla Boutique Hotel Casco Viejo

Amarla Boutique Hotel Casco Viejo

3 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,426, price is now $960 per person
$960
per person
Feb 26 - Mar 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9.6/10 Exceptional! (99 reviews)
The hotel was lovely overall. The room was nice and clean but we didn’t realize there were no windows. Out room door was on an interior balcony that seemed to look over a courtyard, but there was a shade over the courtyard so we couldn’t look down onto anything. The shower was amazing! Very nice, helpful staff. There was a restaurant downstairs which is supposed to be very nice but we only had coffee and breakfast there.

Reviewed on Dec 8, 2025

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $967, price is now $659 per person
$659
per person
Feb 26 - Mar 3
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Panama City (PTY)
9/10 Wonderful! (4,515 reviews)
I will definitely be back !

Reviewed on Dec 27, 2025

Where to stay in Punta Paitilla

Find the best Punta Paitilla areas and neighborhoods for the activities you enjoy most. Learn more about Punta Paitilla
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Find hotels in Casco Viejo

Punta Paitilla Hotel Deals

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $236 total per night from Jan 8 to Jan 9
$236 total
Jan 8 - Jan 9, 2026
Total with taxes and fees
8.4/10 Very Good! (1,292 reviews)
Big rooms, excellent food choices

Reviewed on Dec 20, 2025

Megapolis Hotel Panamá
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Fully refundableReserve now, pay when you stay
$116 nightly
The price is $129 total per night from Jan 25 to Jan 26
$129 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
9/10 Wonderful! (1,007 reviews)
Beautiful hotel. Comfortable and well-appointed room, delicious breakfast, helpful staff. Recommended.

Reviewed on Dec 21, 2025

Las Americas Golden Tower Panama
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

3.5 out of 5
Italy Avenue, Punta Paitilla Panama City Panama
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $102 total per night from Jan 4 to Jan 5
$102 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.2/10 Wonderful! (2,140 reviews)
They have not any cafeteria o some place inside for shack

Reviewed on Dec 26, 2025

Plaza Paitilla Inn Hotel
See all 1,710 properties in Punta Paitilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
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Kid Friendly Vacations

Discover the most popular places to visit in Punta Paitilla

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa

Things to do

Boat tour in the Panama Canal to Monkeys and sloths islands

Boat tour in the Panama Canal to Monkeys and sloths islands

$67
per adult
100% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

$155
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Glass Observation Deck Ticket with VR Tour

$32
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
See all activities in Panama City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.