Puxico Vacations

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Puxico Hotel Deals

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 out of 5
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from May 17 to May 18
$105 total
May 17 - May 18
Total with taxes and fees
9.4/10 Exceptional! (832 reviews)
The room was clean. Staff was friendly. We did not eat breakfast. Parking was ample. The hotel was very quiet. Would definitely stay here again.

Reviewed on May 7, 2026

Hampton Inn Poplar Bluff
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2 out of 5
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from May 10 to May 11
$73 total
May 10 - May 11
Total with taxes and fees
8/10 Very Good! (1,003 reviews)
Clean and basic

Reviewed on May 8, 2026

Motel 6 Poplar Bluff, MO
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3 out of 5
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $106 total per night from May 17 to May 18
$106 total
May 17 - May 18
Total with taxes and fees
9.2/10 Wonderful! (1,008 reviews)
Would definitely stay here again! Was a beautiful room and allowed us to have our fur babies!

Reviewed on May 4, 2026

Drury Inn & Suites Poplar Bluff
See all 59 properties in Puxico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Puxico Vacation Packages

Puxico Essential Information

Language
English
Currency
U.S dollars
Population
870

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Frequently asked questions

How much does a Puxico vacation package cost?
You can grab a vacation package to this top destination on Expedia. However, how much your vacation to Puxico costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Puxico?
February, April and August are the best times to look for cheap Puxico vacation packages. Opting to travel in less busy months means you can usually find reduced prices on accommodations and flights.
How many days is enough for Puxico?
Typically, a handful of days is enough to explore the major attractions during your Puxico vacation. However, if you prefer to have more time to chill out or go on day trips, think about extending your itinerary.
How to find the best Puxico package deals?
Use Expedia's handy filters to help you find some unbeatable Puxico package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you want to save, plan your adventure for midweek, or look for Puxico package deals in the off-season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Puxico vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll typically score a better deal than booking each component separately. And you'll still enjoy the flexibility to create a customized Puxico vacation by choosing your preferred airline, accommodation type and car class.
When to book a vacation package to Puxico?
If you're planning a spur-of-the-moment Puxico adventure, check out our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can find incredible deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Puxico vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Puxico trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.