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Reserva Natural Punta Patiño Vacations from $644

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The Latest Reserva Natural Punta Patiño Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Front of property
    Sep 12 - Sep 16

    Decapolis Hotel Panama City + Flight

    San Francisco
    4 nights
    4.0 star property
    8.6/10 - Excellent (1,718 reviews)
    Roundtrip • Kingston (KIN) - Panama City (PTY)
    KIN - PTY • Nonstop PTY - KIN • Nonstop
    $911
    $644
    per traveler
    found 1 day ago
    Decapolis Hotel Panama City
  • Front of property
    Sep 24 - Sep 29

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    5 nights
    4.0 star property
    9.2/10 - Wonderful (1,006 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    Save 100% on your flight
    $2,106
    $1,120
    per traveler
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Front of property
    Oct 2 - Oct 6

    Megapolis Hotel Panamá + Flight

    San Francisco
    4 nights
    4.5 star property
    8.4/10 - Very Good (1,626 reviews)
    "Buen servicion el hotel en perfecta condiciones 10 de 10"
    Reviewed August 2, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,690
    $1,011
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Exterior
    Sep 24 - Sep 29

    Riande Aeropuerto Hotel & Casino + Flight

    Tocumen
    5 nights
    4.0 star property
    8.4/10 - Very Good (1,811 reviews)
    "Poor Wi-Fi. Poor service at the restaurant."
    Reviewed August 2, 2026
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,338
    $928
    per traveler
    found 1 day ago
    Riande Aeropuerto Hotel & Casino
  • Outdoor pool, sun loungers
    Oct 8 - Oct 12

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    4 nights
    5.0 star property
    9.0/10 - Wonderful (5,761 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,200
    $912
    per traveler
    found 1 day ago
    Hotel Riu Plaza Panama
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.