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Reserva Natural Punta Patiño Vacations from $840

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The Latest Reserva Natural Punta Patiño Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Front of property
    Sep 6 - Sep 12

    Decapolis Hotel Panama City + Flight

    San Francisco
    6 nights
    4.0 star property
    8.6/10 - Excellent (1,718 reviews)
    Roundtrip • Georgetown (GEO) - Panama City (PTY)
    GEO - PTY • Nonstop PTY - GEO • Nonstop
    $1,202
    $840
    per traveler
    found 1 day ago
    Decapolis Hotel Panama City
  • Front of property
    Oct 22 - Oct 25

    Central Hotel Panama Casco Viejo + Flight

    Casco Viejo
    3 nights
    4.0 star property
    9.2/10 - Wonderful (1,007 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,618
    $963
    per traveler
    found 1 day ago
    Central Hotel Panama Casco Viejo
  • Front of property
    Oct 22 - Oct 25

    Megapolis Hotel Panamá + Flight

    San Francisco
    3 nights
    4.5 star property
    8.4/10 - Very Good (1,627 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,470
    $913
    per traveler
    found 1 day ago
    Megapolis Hotel Panamá
  • Outdoor pool, sun loungers
    Oct 22 - Oct 25

    Hotel Riu Plaza Panama + Flight

    Bella Vista
    3 nights
    5.0 star property
    9.0/10 - Wonderful (5,761 reviews)
    Roundtrip • New York (EWR) - Panama City (PTY)
    JFK - PTY • Nonstop PTY - JFK • Nonstop
    $1,315
    $955
    per traveler
    found 1 day ago
    Hotel Riu Plaza Panama
  • Exterior
    Sep 10 - Sep 16

    Yoo by Wynwood House + Flight

    Calidonia
    6 nights
    4.0 star property
    9.4/10 - Exceptional (6 reviews)
    "Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about..."
    Reviewed July 26, 2025
    Roundtrip • Kingston (KIN) - Panama City (PTY)
    KIN - PTY • Nonstop PTY - KIN • Nonstop
    $1,572
    $1,180
    per traveler
    found 8 hours ago
    Yoo by Wynwood House
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.