Title: Río Grande Vacation Packages 2026 from $628 | Expedia.com

[Río Grande Travel Guide](https://expedia.com/Rio-Grande.dx829297037045403648)[Hotels in Río Grande](https://expedia.com/Rio-Grande-Hotels.d829297037045403648.Travel-Guide-Hotels)[Vacation Rentals in Río Grande](https://expedia.com/Rio-Grande-Vacation-Rentals.d829297037045403648.Travel-Guide-VacationRentals)[Flights to Río Grande](https://expedia.com/Cheap-Flights-To-Rio-Grande.d829297037045403648.Travel-Guide-Flights)[Car Rentals in Río Grande](https://expedia.com/Car-Rentals-In-Rio-Grande.d829297037045403648.Car-Rental-Guide)

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# Río Grande Vacations from $628

## Book a Hotel + Flight or Car together to unlock savings

- ##  
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- ###  
Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
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With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

## The Latest Río Grande vacation packages

Price found within the past 48 hours. Click for updated prices.

![Mahogany Suites](https://images.trvl-media.com/lodging/119000000/118410000/118402400/118402387/179ad971_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Mahogany Suites

$628

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

10/10 Exceptional! (1 review)

Excellent apartment on a golf resort. 5 Star.

Reviewed on Jan 28, 2026

![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,092

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (1,002 reviews)

Room was clean and comfortable. Staff was very friendly and helpful. Breakfast was very good

Reviewed on Feb 15, 2026

![Villa Botero By Casa Mojito B&B](https://images.trvl-media.com/lodging/12000000/11930000/11927200/11927153/393d35f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Villa Botero By Casa Mojito B&B

$889

per person

Apr 30 - May 7

found 1 day ago

Roundtrip flight included

New York (NYC) to Panama City (PTY)

9.8/10 Exceptional! (60 reviews)

We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.

Reviewed on Jan 22, 2026

![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Riu Plaza Panama

Bella Vista

$771

per person

Apr 19 - Apr 24

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9/10 Wonderful! (4,515 reviews)

The room was clean and the staff were extremely eager to accommodate.

Reviewed on Feb 15, 2026

![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Megapolis Hotel Panamá

San Francisco

$925

per person

May 13 - May 17

found 19 hours ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

8.4/10 Very Good! (1,204 reviews)

Nice hotel. Friendly staff

Reviewed on Feb 9, 2026

Don't see what you're looking for?

See all available trips from Columbus to Río Grande

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-16/2026-03-23/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=RIH&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_829297037045403648)

## Río Grande Hotel Deals

![Charming 3-bedroom countryside Villa in Rio Grande with Pool, WiFi, AC](https://images.trvl-media.com/lodging/109000000/108900000/108897000/108896957/6ecb47f3_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Charming 3-bedroom countryside Villa in Rio Grande with Pool, WiFi, AC

 Rio Grande Coclé Province

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=108896957&PinnedHotelID=108896957&HadPinnedHotel=true&regionId=829297037045403648)

[](https://expedia.com/Hotel-Search?startDate=3%2F2%2F2026&endDate=3%2F3%2F2026&selected=108896957&PinnedHotelID=108896957&HadPinnedHotel=true&regionId=829297037045403648)

![Hotel Coclé](https://images.trvl-media.com/lodging/16000000/15550000/15542300/15542221/23593d5b_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Coclé

Via Interamericana Penonome Cocle

Fully refundableReserve now, pay when you stay

$68 nightly

$74 total

Feb 18 - Feb 19

Total with taxes and fees

8.6/10 Excellent! (212 reviews)

No free breakfast.i went outside of hotel for breafast

Reviewed on Jan 9, 2026

[](https://expedia.com/Hotel-Search?startDate=2%2F18%2F2026&endDate=2%2F19%2F2026&selected=15542221&PinnedHotelID=15542221&HadPinnedHotel=true&regionId=829297037045403648)

![Hotel Las Catalinas Antón](https://images.trvl-media.com/lodging/20000000/19900000/19899700/19899682/0068d751_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Las Catalinas Antón

Ave, 2da #6 Anton Antón

$38 nightly

$42 total

Feb 19 - Feb 20

Total with taxes and fees

8.2/10 Very Good! (28 reviews)

Very sweet boutique hotel in a safe and calm little town. Located to many good food options.

Reviewed on Dec 2, 2025

[](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=19899682&PinnedHotelID=19899682&HadPinnedHotel=true&regionId=829297037045403648)

[See all 48 properties in Río Grande](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F17%2F2026&endDate=2%2F18%2F2026&regionId=829297037045403648)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Río Grande Vacation Packages

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## Frequently asked questions

### How to find the best Río Grande package deals?

### When to book a vacation package to Río Grande?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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