Río Grande Vacations from $808

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The Latest Río Grande vacation packages

Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Oct 13 - Oct 18
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (932 reviews)
Quaint architecture, well maintained, loved walking around Casco Viejo day and night!

Reviewed on Jul 17, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Sep 4 - Sep 9
found 22 hours ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
The Sands by Wynwood House

The Sands by Wynwood House

2 out of 5
Calidonia
Save 100% on your flight
per person
Aug 25 - Aug 29
found 12 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
No reviews
The Gray by Wynwood House

The Gray by Wynwood House

2 out of 5
Bella Vista
Save 100% on your flight
per person
Aug 25 - Aug 29
found 12 hours ago
Roundtrip flight included
New York (JFK) to Panama City (PTY)
No reviews
Departamento de lujo Yoo-Panamá 34B

Departamento de lujo Yoo-Panamá 34B

2 out of 5
Bella Vista
per person
Aug 21 - Aug 26
found 8 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
6/10 (1 review)
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Río Grande Hotel Deals

Charming 3-bedroom countryside Villa in Rio Grande with Pool, WiFi, AC

Charming 3-bedroom countryside Villa in Rio Grande with Pool, WiFi, AC

2 out of 5
Rio Grande
Get rates
Charming 3-bedroom countryside Villa in Rio Grande with Pool, WiFi, AC
Hotel Coclé

Hotel Coclé

3.5 out of 5
Via Interamericana, Iguana Mall shopping center, Penonome, Cocle
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $74 total per night from Jul 25 to Jul 26
$74 total
Jul 25 - Jul 26
Total includes taxes and fees
8.6/10 Excellent! (192 reviews)
"Straight forward simlw room, not fancy, basic snd everything worked."

Reviewed on Jun 26, 2025

Hotel Coclé
Mi Casa Asi de Grande

Mi Casa Asi de Grande

3 out of 5
INTER-AMERICAN HIGHWAY/ PAN-AMERICAN, Edificio Plaza Lis, 1er Nivel, Local 6, El Coco, Cocle
Fully refundableReserve now, pay when you stay
Críticas
"En general fue aceptable, pero pudo ser mejor, porque faltaron detalles como agua caliente, lugar para colocar toallas y jabones. No hay teléfono en habitación. Closet sin ganchos."

Reviewed on Feb 7, 2024

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Mi Casa Asi de Grande
See all 52 properties in Río Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Río Grande Vacation Packages

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Frequently asked questions

How to find the best Río Grande package deals?
Begin your search for a Río Grande package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Río Grande package deal straight away, simply switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Río Grande adventure underway.
When to book a vacation package to Río Grande?
If you've got your Río Grande travel dates finalized, book early to score some fantastic deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are great for traveling on a whim.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.