Río Sereno Vacations from $975
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The Latest Río Sereno vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,090
per person
Oct 14 - Oct 21
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco.
The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.
Reviewed on Sep 2, 2026
Río Sereno Hotel Deals
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundableReserve now, pay when you stay
$96 nightly
$106 total
Sep 3 - Sep 4
Total with taxes and fees
8.2/10 Very Good! (267 reviews)
"Me gusto todo. La habitación con una vista increíble, el restaurante muy bien atendido y buena cómida. La piscina climatizada es genial"
Reviewed on Aug 30, 2026
Hotel Finca Lerida
Alto Quiel Los Naranjos Chiriqui
$159 nightly
$176 total
Sep 10 - Sep 11
Total with taxes and fees
8.8/10 Excellent! (210 reviews)
"Un buen ambiente para estar tranquilo con la naturaleza."
Reviewed on Aug 20, 2026
Casa Grande Bambito Resort
Calle El Manantial Paso Ancho Chiriqui
8.4/10 Very Good! (99 reviews)
"We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ..."
Reviewed on Jan 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions
How to find the best Río Sereno package deals?
Use Expedia's filter tool to help you find some fabulous Río Sereno package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Río Sereno package deals in the low season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as early as possible.
When to book a vacation package to Río Sereno?
If you're planning a spontaneous Río Sereno trip, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score terrific deals on your hotels and flights by booking well in advance.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
