Ruta Independencia Vacations from $881

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Your Ruta Independencia Vacation

Our Ruta Independencia vacation packages are a simple and practical way to arrange and book your next retreat. Uncover the true character of this unique neighborhood without the bother of having to plan everything yourself. Some top nearby attractions to visit during your trip to Ruta Independencia include Zocalo Square, Church of Santo Domingo de Guzman and Auditorio Guelaguetza. Stop daydreaming and start doing. When it's time to lock in your next vacation to Ruta Independencia, Expedia is here to help.

The Latest Ruta Independencia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Fortin Plaza

Hotel Fortin Plaza

Save 100% on your flight
$881
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
8.8/10 Excellent! (1,007 reviews)
Everything was excellent at Hotel Fortin Plaza

Reviewed on Aug 26, 2026

Casa Quiote Hotel Boutique City Center based - Adults Only

Casa Quiote Hotel Boutique City Center based - Adults Only

Oaxaca Centro
Save 100% on your flight
$1,084
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9/10 Wonderful! (76 reviews)
Exelente trato, limpieza y amabilidad, un servicio de primer orden.

Reviewed on Aug 12, 2026

Casa 1800 Oaxaca Boutique Hotel

Casa 1800 Oaxaca Boutique Hotel

Oaxaca Centro
Save 100% on your flight
$948
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (96 reviews)
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

Oaxaca Centro
Save 100% on your flight
$1,022
per person
Nov 3 - Nov 10
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9.4/10 Exceptional! (1,031 reviews)
Sauvé Casa Boutique

Sauvé Casa Boutique

Oaxaca Centro
Save 100% on your flight
$1,474
per person
Nov 10 - Nov 17
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (128 reviews)

Where to stay in Ruta Independencia

Find the best Ruta Independencia areas and neighborhoods for the activities you enjoy most. Learn more about Ruta Independencia
A historic courtyard with a fountain, arches, and a dome structure.

Oaxaca Centro

7 out of top 10 points of interest in this area

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Find hotels in Oaxaca Centro
A narrow cobblestone street flanked by colorful buildings with balconies and hanging plants.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Find hotels in Jalatlaco
A colorful dragon sculpture with vibrant orange, yellow, blue, and green feathers.

Reforma

If you're spending some time in Reforma, Plaza Mazari and Plaza Parque are top sights worth seeing.

Find hotels in Reforma
A person with arms raised, a colorful hot air balloon, and ancient ruins in the background.

Santa Lucía del Camino

1 out of top 10 points of interest in this area

When in Santa Lucía del Camino, you can plan a visit to Oaxaca Cultural and Convention Center and El Llano Park, some noteworthy sights in the nearby area.

Find hotels in Santa Lucía del Camino
A mountainous landscape with dense forests and a winding road.

San Felipe del Agua

You'll enjoy the restaurants and museums in San Felipe del Agua. You might want to make time for a stop at Parque Comunal or Loma del Pelado Trailhead.

Find hotels in San Felipe del Agua

Ruta Independencia Hotel Deals

Quinta Real Oaxaca

Quinta Real Oaxaca

Calle 5 De Mayo 300 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$310 nightly
$369 total
Sep 16 - Sep 17
Total with taxes and fees
Quinta Real Oaxaca
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

Jose Maria Pino Suarez 702 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$249 nightly
$302 total
Sep 27 - Sep 28
Total with taxes and fees
Grand Fiesta Americana Oaxaca
Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG

Diaz Quintas 115, Col. Centro Oaxaca OAX
$115 nightly
$137 total
Sep 14 - Sep 15
Total with taxes and fees
9.6/10 Exceptional! (1,003 reviews)
"Excellent services hotel clean and near to the zocalo"

Reviewed on Aug 18, 2026

Holiday Inn Express Oaxaca-Centro Historico by IHG
See all 972 properties in Ruta Independencia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Solo Vacations

Stay near popular Ruta Independencia attractions

A historic stone building with a bell tower and palm trees.

Church of Santo Domingo de Guzmán

9.6/10 (3,897 reviews)
Church of Santo Domingo de Guzmán is just one of the places to see in Oaxaca, so why not enjoy the other things to explore during your travels? While in this culturally rich area, find time to visit its shops.
See properties
A historic cathedral with two bell towers and a courtyard with palm trees.
Photo by Sergio Camalich

Santo Domingo Square

9.6/10 (3,062 reviews)
During your trip to Oaxaca, you can find the perfect gifts to bring home at Santo Domingo Square. Discover the art scene and cathedral in this culturally rich area.
See properties
An aerial view of a historic building complex with multiple courtyards and surrounding greenery.

Oaxaca Ethnobotanical Garden

9.0/10 (1,570 reviews)
Explore the great outdoors at Oaxaca Ethnobotanical Garden, a lovely green space in Oaxaca. While in this culturally rich area, find time to visit its shops.
See properties
A historic cathedral with two prominent towers and a large dome.
Photo by Julie Ruth

Andador de Macedonia Alcala

9.4/10 (365 reviews)
You can find the perfect gifts to bring home at Andador de Macedonia Alcala during your stay in Oaxaca. While you're here, you can savor the top-notch restaurants.
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El Llano Park

9.0/10 (911 reviews)
Explore the great outdoors at El Llano Park, a lovely green space in Oaxaca. While in this culturally rich area, find time to visit its shops.
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Jardín Etnobotánico

Learn about the local history of Oaxaca when you spend time at Jardín Etnobotánico. While in this culturally rich area, find time to visit its shops.
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Merced Market

8.0/10 (1 review)
During your trip to Oaxaca, you can browse for the perfect souvenirs at Merced Market. You can seek out the local tours in this culturally rich area.
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Museum of Oaxacan Culture

9.4/10 (14 reviews)
You can spend an afternoon exploring the galleries in Museum of Oaxacan Culture in Oaxaca. While in this culturally rich area, find time to visit its shops.
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Things to do

Bike tour to the Tule Tree and the Gastronomic Market

Bike tour to the Tule Tree and the Gastronomic Market

$34
per adult
Bike tour to the Tule Tree and the Gastronomic Market
Tour in Oaxaca Monte Alban Mezcal Alebrijes and Barro Negro

Monte Alban, Ancestral Mezcal, Alebrijes and Black Mud Tour

$34
per adult
Monte Alban, Ancestral Mezcal, Alebrijes and Black Mud Tour
Oaxaca de Juarez: Monte Alban Half-Day Tour

Oaxaca de Juarez: Monte Alban Half-Day Tour

$34
per adult
96% of travellers recommend
Oaxaca de Juarez: Monte Alban Half-Day Tour
See all activities in Oaxaca
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.