Ruta Independencia Vacations from $349

Book a Hotel + Flight or Car together to unlock savings

Photo by Marina Alcantara

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Ruta Independencia Vacation

Our Ruta Independencia vacation packages are a simple and practical way to arrange and book your next retreat. Uncover the true character of this unique neighborhood without the bother of having to plan everything yourself. Some top nearby attractions to visit during your trip to Ruta Independencia include Zocalo Square, Church of Santo Domingo de Guzman and Auditorio Guelaguetza. Stop daydreaming and start doing. When it's time to lock in your next vacation to Ruta Independencia, Expedia is here to help.

The Latest Ruta Independencia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Capital O Parador Crespo Hotel, Oaxaca

Capital O Parador Crespo Hotel, Oaxaca

3 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $601, price is now $349 per person
$349
per person
Jun 20 - Jun 27
found 10 hours ago
Roundtrip non-stop flight included
Ciudad Juarez (CJS) to Oaxaca Intl. (OAX)
7.8/10 Good! (264 reviews)
Closed to everything u can walk to downtown.

Reviewed on Feb 26, 2026

Hotel Angel Inn

Hotel Angel Inn

3.5 out of 5
San Felipe del Agua
Save 100% on your flight
Price was $985, price is now $543 per person
$543
per person
Jun 20 - Jun 27
found 1 day ago
Roundtrip non-stop flight included
Ciudad Juarez (CJS) to Oaxaca Intl. (OAX)
8.6/10 Excellent! (118 reviews)
Nice looking property in what looked to be an interesting part of Oaxaca. Room was spacious, clean and complex was the same. Bed was too hard for me, but I realize many like that. I will stay there tambien!

Reviewed on Sep 3, 2024

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

3.5 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $1,220, price is now $702 per person
$702
per person
Jun 20 - Jun 27
found 1 day ago
Roundtrip non-stop flight included
Ciudad Juarez (CJS) to Oaxaca Intl. (OAX)
9.2/10 Wonderful! (1,003 reviews)
Love this hotel , definitely will come back to this one

Reviewed on Apr 15, 2026

Hotel De La Parra

Hotel De La Parra

4 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $1,498, price is now $869 per person
$869
per person
Jun 20 - Jun 27
found 1 day ago
Roundtrip non-stop flight included
Ciudad Juarez (CJS) to Oaxaca Intl. (OAX)
9.2/10 Wonderful! (529 reviews)
Well, the hotel don’t have any amenities you have to go out of the hotel to look for it. I’ve been in this hotel, many many times and they need to renovated. I know they’re trying to keep it a little bit like All hotel, but to be honest with you it’s very expensive and it’s to all the furniture is really all the bed that I really all.

Reviewed on Apr 16, 2026

Casa De Sierra Azul

Casa De Sierra Azul

3.5 out of 5
Oaxaca Centro
Save 100% on your flight
Price was $1,021, price is now $613 per person
$613
per person
Jun 20 - Jun 27
found 1 day ago
Roundtrip non-stop flight included
Ciudad Juarez (CJS) to Oaxaca Intl. (OAX)
9.2/10 Wonderful! (936 reviews)
Very good menu everything is fresh and delicious.

Reviewed on Apr 2, 2026

Where to stay in Ruta Independencia

Find the best Ruta Independencia areas and neighborhoods for the activities you enjoy most. Learn more about Ruta Independencia
Oaxaca Centro

Oaxaca Centro

7 out of top 10 points of interest in this area
4.5/5(702 area reviews)

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Find hotels in Oaxaca Centro

Ruta Independencia Hotel Deals

One Oaxaca Centro Hotel

One Oaxaca Centro Hotel

3 out of 5
Calzada de la Republica #205 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $89 total per night from Apr 18 to Apr 19
$89 total
Apr 18 - Apr 19
Total with taxes and fees
8.8/10 Excellent! (1,000 reviews)
Good pace and location , only thing was the beds were too hard. Woke up with my back hurting

Reviewed on Apr 6, 2026

One Oaxaca Centro Hotel
Quinta Real Oaxaca

Quinta Real Oaxaca

4.5 out of 5
Calle 5 De Mayo 300 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$292 nightly
The price is $348 total per night from Apr 24 to Apr 25
$348 total
Apr 24 - Apr 25
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
There are not enough stars to rate our stay at Quinta Real Oaxaca. We stayed for 9 days and have never been treated so well in all our days. The property is a real jewel. So unique. The staff are the best you could ever find and enhanced our experience ten fold. 5/5 stars +++

Reviewed on Apr 8, 2026

Quinta Real Oaxaca
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

5 out of 5
Jose Maria Pino Suarez 702 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$276 nightly
The price is $332 total per night from May 18 to May 19
$332 total
May 18 - May 19
Total with taxes and fees
9.6/10 Exceptional! (733 reviews)
Amazing staff! Really the best! I'm so grateful. They made our stay so special

Reviewed on Apr 16, 2026

Grand Fiesta Americana Oaxaca
See all 946 properties in Ruta Independencia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Ruta Independencia

Église Santo Domingo de Guzmán, Oaxaca

Church of Santo Domingo de Guzmán

5/5(288 reviews)

Church of Santo Domingo de Guzmán is just one of the places to see in Oaxaca, so why not enjoy the other things to explore during your travels? While in this culturally rich area, find time to visit its shops.

Church of Santo Domingo de Guzmán
Aerial views of the Ex-convent of Santo Domingo in the City of Oaxaca, Mexico, the roofs are reddish and there is an ethnobotanical garden

Oaxaca Ethnobotanical Garden

4.5/5(187 reviews)

Explore the great outdoors at Oaxaca Ethnobotanical Garden, a lovely green space in Oaxaca. While in this culturally rich area, find time to visit its shops.

Oaxaca Ethnobotanical Garden
Santo Domingo Square

Santo Domingo Square

4.5/5(122 reviews)

During your trip to Oaxaca, you can find the perfect gifts to bring home at Santo Domingo Square. Discover the art scene and cathedral in this culturally rich area.

Santo Domingo Square

Things to do

Bike tour to the Tule Tree and the Gastronomic Market

Bike tour to the Tule Tree and the Gastronomic Market

$30
per adult
Bike tour to the Tule Tree and the Gastronomic Market
Monte Alban, Alebrijes & Black Pottery: Oaxaca Essential Day Tour

Monte Alban, Alebrijes & Black Pottery: Oaxaca Essential Day Tour

$42
per adult
100% of travellers recommend
Monte Alban, Alebrijes & Black Pottery: Oaxaca Essential Day Tour
Oaxaca: First Day in Oaxaca — Walk with Your Personal Guide

Oaxaca: First Day in Oaxaca — Walk with Your Personal Guide

$20
per adult
Oaxaca: First Day in Oaxaca — Walk with Your Personal Guide
See all activities in Oaxaca
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.