Ruta Independencia Vacations from $739
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Your Ruta Independencia Vacation
Our Ruta Independencia vacation packages are a simple and practical way to arrange and book your next retreat. Uncover the true character of this unique neighborhood without the bother of having to plan everything yourself. Some top nearby attractions to visit during your trip to Ruta Independencia include Zocalo Square, Church of Santo Domingo de Guzman and Auditorio Guelaguetza. Stop daydreaming and start doing. When it's time to lock in your next vacation to Ruta Independencia, Expedia is here to help.
The Latest Ruta Independencia Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Casa de Adobe Gallery & Luxury Boutique
San Felipe del Agua
$1,366
per person
Dec 10 - Dec 14
found 11 hours ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9.2/10 Wonderful! (220 reviews)
Clean rooms, helpful staff, front desk spoke English, and restaurant staff were more than happy to find someone who did if we were having issues communicating. Food was good, pool was clean, very quiet hotel, which is exactly what we were looking for. The pool became more lively in the evenings with kids, but they were respectful and it was always quiet by night time.
Reviewed on Aug 29, 2026
Ébano Hotel Boutique
Oaxaca Centro
$1,018
per person
Nov 29 - Dec 3
found 19 hours ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9.4/10 Exceptional! (495 reviews)
Beautiful boutique hotel. Staff was super friendly. Great location within walking distance from all the main streets and shops.
Reviewed on Aug 25, 2026
Casa Quiote Hotel Boutique City Center based - Adults Only
Oaxaca Centro
$873
per person
Nov 29 - Dec 3
found 19 hours ago
Roundtrip non-stop flight included
Chicago (CHI) to Oaxaca Intl. (OAX)
9/10 Wonderful! (83 reviews)
This hotel is the most perfect hotel in Oaxaca. It’s clean, beautiful, and has the kindest staff. I left my ipad there by accident after check out and they immediately called me back to get it. 10/10 service
Reviewed on Oct 16, 2026
Grand Fiesta Americana Oaxaca
Oaxaca Centro
$2,862
per person
Dec 23 - Dec 28
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Oaxaca Intl. (OAX)
9.6/10 Exceptional! (824 reviews)
I really enjoyed all my interactions with the hotel workers. They were very helpful throughout the entire experience, and I would definitely recommend them for their staff! I would also like to say the bar menu options were great. The rooms were clean, which they also frequently asked if we would like to be cleaned again throughout our trip.
Reviewed on Oct 12, 2026
Where to stay in Ruta Independencia
Find the best Ruta Independencia areas and neighborhoods for the activities you enjoy most. Learn more about Ruta Independencia
Oaxaca Centro
7 out of top 10 points of interest in this area
Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.
Jalatlaco
While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.
Reforma
If you're spending some time in Reforma, Plaza Parque and Plaza Mazari are top sights worth seeing.
Santa Cruz Xoxocotlán
1 out of top 10 points of interest in this area
Visitors to Santa Cruz Xoxocotlán like its archaeological sites and cafes, and Monte Albán is a sight worth a stop.
Santa Lucía del Camino
1 out of top 10 points of interest in this area
When in Santa Lucía del Camino, you can plan a visit to Oaxaca Cultural and Convention Center and El Llano Park, some noteworthy sights in the nearby area.
Ruta Independencia Hotel Deals
Quinta Real Oaxaca
Calle 5 De Mayo 300 Oaxaca OAX
Fully refundableReserve now, pay when you stay
$345 nightly
$423 total
Nov 17 - Nov 18
Total with taxes and fees
9.6/10 Exceptional! (1,001 reviews)
"We loved Quinta Real. It’s beautiful and well maintained. The staff were all kind and gracious. The neighborhood is also wonderful. We were sad to leave!"
Reviewed on Oct 14, 2026
Holiday Inn Express Oaxaca-Centro Historico by IHG
Diaz Quintas 115, Col. Centro Oaxaca OAX
Fully refundable
$110 nightly
$131 total
Nov 8 - Nov 9
Total with taxes and fees
9.6/10 Exceptional! (1,000 reviews)
"Clean room excellent location"
Reviewed on Oct 13, 2026
One Oaxaca Centro Hotel
Calzada de la Republica #205 Oaxaca OAX
$84 nightly
$100 total
Oct 18 - Oct 19
Total with taxes and fees
8.8/10 Excellent! (1,000 reviews)
"Excelente hotel muy comodo, limpio y sobre todo muy centrico en el mero centro a unas varias cuadras de todo.... Los unicos PEROS que le pongo son por cosas menores como que las habitaciones son pequenas pero yo se que asi son las cadenas de ONE en todas partes... y queel desayuno es 2-3 nada espectacular ..."
Reviewed on Sep 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Ruta Independencia attractions
Church of Santo Domingo de Guzmán
9.6/10 (3,897 reviews)
Church of Santo Domingo de Guzmán is just one of the places to see in Oaxaca, so why not enjoy the other things to explore during your travels? While in this culturally rich area, find time to visit its shops.
Photo by Sergio Camalich
Santo Domingo Square
9.6/10 (3,062 reviews)
During your trip to Oaxaca, you can find the perfect gifts to bring home at Santo Domingo Square. Discover the art scene and cathedral in this culturally rich area.
Photo by Julie Ruth
Andador de Macedonia Alcala
9.4/10 (365 reviews)
You can find the perfect gifts to bring home at Andador de Macedonia Alcala during your stay in Oaxaca. While you're here, you can savor the top-notch restaurants.
El Llano Park
9.0/10 (911 reviews)
Explore the great outdoors at El Llano Park, a lovely green space in Oaxaca. While in this culturally rich area, find time to visit its shops.
Jardín Etnobotánico
Learn about the local history of Oaxaca when you spend time at Jardín Etnobotánico. While in this culturally rich area, find time to visit its shops.
Museum of Oaxacan Painters
8.8/10 (58 reviews)
You can spend an afternoon studying the exhibits at Museum of Oaxacan Painters during your travels in Oaxaca. Check out the shops and top-notch restaurants in this culturally rich area.
Graphic Arts Institute of Oaxaca
9.0/10 (49 reviews)
You can spend an afternoon browsing the exhibits at Graphic Arts Institute of Oaxaca during your trip to Oaxaca. Check out the shops and top-notch restaurants in this culturally rich area.
Museum of Oaxacan Culture
9.4/10 (14 reviews)
You can spend an afternoon exploring the galleries in Museum of Oaxacan Culture in Oaxaca. While in this culturally rich area, find time to visit its shops.
Things to do
Monte Alban, Ancestral Mezcal, Alebrijes and Black Mud Tour
$35
per adult
Bike tour to the Tule Tree and the Gastronomic Market
$35
per adult
Oaxaca de Juarez: Monte Alban Half-Day Tour
$31
per adult
96% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.