Photo by Holly Smith

Search Guest Houses in Saint Leo

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Next weekend
Dec 12 - Dec 14
In two weeks
Dec 19 - Dec 21
In one month
Jan 2 - Jan 4
In two months
Jan 30 - Feb 1

Guest Houses in Saint Leo

No exact matches found, but these alternatives could be just right

Recommended hotels in Saint Leo

Exterior
Hampton Inn Brooksville Dade

Hampton Inn Brooksville Dade

2.5 star property
Brooksville
9.0 out of 10, Wonderful, (442)
"The room was clean and the bed was comfortable. Room service was invisible given our schedule but provided fresh towels and room tidying everyday. We had room excess from both inside and outside the room. The area was quiet even though it was right off SR 98. The morning breakfast was great also."
United States
Rita
$118 nightly
The price is $132
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hampton Inn Brooksville Dade
In-room safe, desk, iron/ironing board, free WiFi
Microtel Inn & Suites by Wyndham Brooksville

Microtel Inn & Suites by Wyndham Brooksville

2.0 star property
Brooksville
8.4 out of 10, Very Good, (1003)
"Convenient to our needs and close to dining areas"
United States
Thomas
$84 nightly
The price is $94
Dec 8 - Dec 9
Total with taxes and fees
Microtel Inn & Suites by Wyndham Brooksville
Outdoor pool
Holiday Inn Express Hotel & Suites Brooksville by IHG

Holiday Inn Express Hotel & Suites Brooksville by IHG

2.5 star property
Brooksville
8.6 out of 10, Excellent, (723)
"Great place to stay for a great price! "
United States
Justin
$105 nightly
The price is $117
Dec 9 - Dec 10
Total with taxes and fees
Holiday Inn Express Hotel & Suites Brooksville by IHG
Exterior
Quality Inn Zephyrhills - Dade City

Quality Inn Zephyrhills - Dade City

2.5 star property
Zephyrhills
7.8 out of 10, Good, (1008)
"Great group, always are..."
United States
wade
$91 nightly
The price is $102
Dec 21 - Dec 22
Total with taxes and fees
Quality Inn Zephyrhills - Dade City
View from room
Roadstar Hotel Zephyrhills

Roadstar Hotel Zephyrhills

2.0 star property
Zephyrhills
9.0 out of 10, Wonderful, (1101)
"Great experience here, clean room, great staff, solid breakfast, l will be back."
United States
Joseph
$81 nightly
The price is $91
Dec 15 - Dec 16
Total with taxes and fees
Roadstar Hotel Zephyrhills
BBQ/picnic area
Days Inn by Wyndham Brooksville/Dade City

Days Inn by Wyndham Brooksville/Dade City

2.0 star property
Brooksville
7.0 out of 10, Good, (1004)
"Room was very clean, they were very friendly to me, and also very sweet to my basset hound. Would stay again no doubt "
United States
Cynthia
$75 nightly
The price is $83
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham Brooksville/Dade City
Exterior
Liberty Hill Executive Inn

Liberty Hill Executive Inn

2.0 star property
Zephyrhills
10.0 out of 10, Exceptional, (2)
"This place is awesome sauce and I recommend Liberty Inn any day. Very convenient check in. Fast and friendly. When I walked in my room, I was every bit of surprised and very very pleased. You should all come check it out. You won't regret it I promise "
United States
Quiana
$91 nightly
The price is $102
Dec 7 - Dec 8
Total with taxes and fees
Liberty Hill Executive Inn
Lobby
Best Western Wesley Chapel

Best Western Wesley Chapel

2.5 star property
Wesley Chapel
8.2 out of 10, Very Good, (1003)
"Clean room and friendly staff "
United States
Shanique
$104 nightly
The price is $116
Dec 14 - Dec 15
Total with taxes and fees
Best Western Wesley Chapel
Lobby
Quality Inn & Suites Brooksville I-75/Dade City

Quality Inn & Suites Brooksville I-75/Dade City

2.5 star property
Brooksville
6.8 out of 10, (766)
"Good breakfast. Room was clean, but the electrical outlet I needed it for my CPAP machine did not work luckily I had a long cord. Bed was comfortable. Minimal soap provided.. Good pricing through Expedia."
United States
Arthur
$71 nightly
The price is $80
Dec 14 - Dec 15
Total with taxes and fees
Quality Inn & Suites Brooksville I-75/Dade City
Lobby
SPOT X Hotel Tampa - Wesley Chapel by The Red Collection

SPOT X Hotel Tampa - Wesley Chapel by The Red Collection

3.0 star property
Wesley Chapel
8.4 out of 10, Very Good, (1002)
"Super convenient location, very clean and friendly staff 👍👍"
United States
Reuven
$107 nightly
The price is $120
Dec 14 - Dec 15
Total with taxes and fees
SPOT X Hotel Tampa - Wesley Chapel by The Red Collection
Free toiletries, hair dryer, towels
Hampton Inn Dade City - Zephyrhills

Hampton Inn Dade City - Zephyrhills

2.5 star property
Dade City
8.8 out of 10, Excellent, (768)
"Everything and everyone was very good ! I love stay there . "
United States
William
$110 nightly
The price is $123
Dec 18 - Dec 19
Total with taxes and fees
Hampton Inn Dade City - Zephyrhills
Front of property - evening/night
Microtel Inn & Suites by Wyndham Zephyrhills

Microtel Inn & Suites by Wyndham Zephyrhills

2.0 star property
Zephyrhills
8.0 out of 10, Very Good, (1001)
"Safe and clean. Plenty of dining nearby"
United States
F. Rick
$89 nightly
The price is $100
Dec 20 - Dec 21
Total with taxes and fees
Microtel Inn & Suites by Wyndham Zephyrhills
Exterior
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG

Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG

3.5 star property
New Tampa
9.0 out of 10, Wonderful, (903)
"Staff was courteous."
United States
Jonnell
$97 nightly
The price is $110
Dec 14 - Dec 15
Total with taxes and fees
Holiday Inn Express Hotel & Suites New Tampa I-75 by IHG
Meeting facility
Hyatt Place Tampa/Wesley Chapel

Hyatt Place Tampa/Wesley Chapel

3.0 star property
Lutz
9.2 out of 10, Wonderful, (1003)
"Breakfast the the staff serving breakfast were amazing! "
United States
Ponciano
$129 nightly
The price is $144
Dec 7 - Dec 8
Total with taxes and fees
Hyatt Place Tampa/Wesley Chapel
Reception
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

3.0 star property
New Tampa
9.0 out of 10, Wonderful, (1001)
"Good place to stay.. "
United States
Ankit
$110 nightly
The price is $125
Dec 14 - Dec 15
Total with taxes and fees
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
Exterior
WoodSpring Suites Wesley Chapel-Tampa

WoodSpring Suites Wesley Chapel-Tampa

2.5 star property
Wesley Chapel
7.6 out of 10, Good, (746)
"Good affordable stay"
United States
daniel
$89 nightly
The price is $100
Dec 14 - Dec 15
Total with taxes and fees
WoodSpring Suites Wesley Chapel-Tampa
Outdoor dining
Fuel Your Passion for Epic Experiences and Outdoor Adventures at the Moto Ranch ATV!

Fuel Your Passion for Epic Experiences and Outdoor Adventures at the Moto Ranch ATV!

Brooksville
9.6 out of 10, Exceptional, (5)
"We very much enjoyed our stay. It was great to be able to ride all day and take breaks whenever we wanted. For the non-riders, we enjoyed relaxing. The home had everything we needed. Looking forward to returning soon."
United States
Allison M.
$158 nightly
The price is $175
Dec 7 - Dec 8
Total with taxes and fees
Fuel Your Passion for Epic Experiences and Outdoor Adventures at the Moto Ranch ATV!
Outdoor dining
The White Door Studio.

The White Door Studio.

2.0 star property
Lutz
$100 nightly
The price is $110
Dec 7 - Dec 8
Total with taxes and fees
The White Door Studio.
Outdoor pool
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel

Fairfield Inn & Suites by Marriott Tampa Wesley Chapel

2.5 star property
Wesley Chapel
9.2 out of 10, Wonderful, (715)
"Everything was great"
United States
Patrick B
$116 nightly
The price is $130
Dec 14 - Dec 15
Total with taxes and fees
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
Lobby
Rodeway Inn

Rodeway Inn

2.0 star property
Wesley Chapel
6.2 out of 10, (963)
"Expensive for the service"
United States
Yessica
$71 nightly
The price is $80
Dec 14 - Dec 15
Total with taxes and fees
Rodeway Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Saint Leo Hotel Reviews

WoodSpring Suites Wesley Chapel-Tampa

WoodSpring Suites Wesley Chapel-Tampa

10/10 Excellent
"Great stay"
Arlyn 1-night trip
Posted 2 days ago
WoodSpring Suites Wesley Chapel-Tampa

Find out more about Saint Leo

Saint Leo Guest Houses information

Number of reviews
15,178
Accommodation
2 Guest Houses
Lowest Price
$80
Highest Price
$175

Frequently asked questions

What is the nightly rate for a guest house in Saint Leo?
Rates for Saint Leo guest houses vary, but travelers can find great-value prices from $80 with Expedia. A range of factors can affect nightly rates, such as the location, the breakfast offering, and the range of amenities. Travelers looking for a good deal should consider looking for a midweek stay, as weekend rates at Saint Leo guest houses tend to be higher. Remember to also use our filters to sort prices from low to high.
What's the difference between a Saint Leo guest house and a B&B?
A guest house in Saint Leo is typically a larger establishment with more rooms, offering a more hotel-like experience, and may provide additional amenities including luxury bedding. In contrast, a B&B is usually a smaller property that focuses primarily on providing a room and breakfast. A B&B is often more personal, and breakfast is typically included as part of the stay, but other services might be more limited compared to a guest house.

Explore a world of travel with Expedia