A coastal landscape with a dense forest, a clear blue sky, and a view of the ocean.

San Antonio Vacations from $645

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Your San Antonio Vacation

San Antonio is calling! Whatever type of escape you're organizing, get ready to discover the best of this neighborhood with a San Antonio vacation package. When it's time to see the sights, you'll find a lot of popular attractions nearby including Dorado Beach, Dorado Del Mar and Balneario Manuel Morales. Tick off one, two or all during your trip to San Antonio. Expedia will help turn your ideal San Antonio vacation into reality, whatever your travel plans or budget.

The Latest San Antonio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 10 - Jan 14

    Hotel Puerto Valdes + Flight

    Puerta de Tierra
    4 nights
    4.0 star property
    8.8/10 - Excellent (763 reviews)
    "I like the place very clean"
    Reviewed November 5, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 1 stop
    Save 100% on your flight
    $1,027
    $645
    per traveler
    found 1 day ago
    Hotel Puerto Valdes
  • Jan 28 - Feb 2

    Isla Verde Beachfront Retreat With Parking + Flight

    Isla Verde
    5 nights
    2.0 star property
    10/10 - Exceptional (7 reviews)
    "Super nice place to stay at Isla Verde. Owner was super friendly and the place is clean,, a lot of space with included kitchen and wash/drying machine. Would consider again for sure."
    Reviewed October 5, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • 1 stop SJU - BOS • 1 stop
    $1,964
    $825
    per traveler
    found 1 day ago
    Isla Verde Beachfront Retreat With Parking
  • Jan 18 - Jan 23

    WALD HAUS by DW + Flight

    Naguabo
    5 nights
    4.0 star property
    9.2/10 - Wonderful (11 reviews)
    "The home itself is absolutely stunning but the road to the villa is not just narrow, it's washed out in many places, we struggled to navigate the potholes even with a jeep and an SUV, I would not drive it at night. There are great amenities like the fridge and bathroom downstairs, the coffee / cocktail bar is fabulous.The kitchen was well-stocked with basic spices and supplies but it was crawling with roaches. Wifi is spotty so be sure to have the guidebook downloaded and screenshots of the..."
    Reviewed August 13, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 2 stops
    $3,891
    $2,459
    per traveler
    found 1 day ago
    WALD HAUS by DW
  • Jan 24 - Jan 28

    Casa Sol 13 by Otium + Flight

    Old San Juan
    4 nights
    2.0 star property
    8.0/10 - Very good (1 review)
    "For a quick trip the property is ideal for its location. The artwork throughout made the place. During our stay we did not have “hot” water, it was slightly warm at best but we didn’t mind since the temps were in high 80s. My only concern was the high humidity in the unit even with the AC on but again it wasn’t a problem since we spent a lot of time out and about. These lil things were not enough concern to bring to management. Bedroom bathroom is a bit tight so I’m happy the 1st level bathroom..."
    Reviewed July 16, 2026
    Roundtrip • New York (EWR) - San Juan (SJU)
    EWR - SJU • Nonstop SJU - EWR • Nonstop
    $1,337
    $846
    per traveler
    found 18 hours ago
    Casa Sol 13 by Otium
  • Jan 18 - Jan 23

    SELVA by DW + Flight

    Pitahaya
    5 nights
    4.0 star property
    10/10 - Exceptional (3 reviews)
    "Todo estuvo perfecto limpieza 💯communication al 💯 y los servicios ofrecido todo me parecio exelente buen olor en las toallas y sabanas ,"
    Reviewed June 25, 2026
    Roundtrip • Boston (BOS) - San Juan (SJU)
    BOS - SJU • Nonstop SJU - BOS • 2 stops
    $5,169
    $3,379
    per traveler
    found 1 day ago
    SELVA by DW

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most.

Old San Juan

The fascinating museums and captivating waterfront views are top of the list for many visitors to Old San Juan. A stop by Port of San Juan or Castillo de San Cristobal might round out your trip.

Condado

Oceanfront and upscale, Condado boasts picturesque beaches alongside hotels, nightclubs, casinos, and shops. Stroll through La Ventana al Mar park, and enjoy easy access to public transport via T21 and D53 bus routes.

Isla Verde

White-sands, beautifully clear water and excellent water sports make this beach one of the most popular in Puerto Rico.

Santurce

Bask in the sun on Atlantic Ocean beaches and experience vibrant nightlife at La Placita de Santurce, while exploring museums like the Museum of Art of Puerto Rico. Enjoy easy access to public transportation via bus lines and the Tren Urbano.

Ocean Park

Upscale beachfront community with trendy beachgoers, Ocean Park offers kitesurfing and windsurfing opportunities. Stroll along Calle Loíza for bars, restaurants, and boutiques or unwind at nearby Parque Barbosa.

San Antonio Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.