San Lorenzo Vacations from $1,143

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Your San Lorenzo Vacation

If you're wanting a food-lovers escape, our San Lorenzo vacation packages are what you need. Whether you want to experience its nightlife, bars and pubs or culture, this neighborhood has something on offer for everyone. Some top nearby attractions to visit during your trip to San Lorenzo include Roman Forum, Pantheon and Piazza Navona. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your budget or travel plans.

The Latest San Lorenzo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Albergo Etico Roma

Albergo Etico Roma

Flaminio
$1,143
per person
Jan 1 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.8/10 Exceptional! (379 reviews)
Gens très accueillant, un gros wow. Je recommande à 100%. Décoration de bon goût, grand confort il ne manque rien!

Reviewed on Oct 18, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$5,237
per person
Nov 20 - Nov 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)
U-Visionary Roma Hotel

U-Visionary Roma Hotel

Rome City Centre
Save 100% on your flight
$2,386
per person
Nov 20 - Nov 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (511 reviews)
Great location, nice hotel. But, our room did not lock from the outside. You could literally push the door open even when in “locked” status. At night, we were able to use the slide lock, so that helped some. Also, our bathroom door would not shut. We had to put something in front of it to keep it semi closed when using.

Reviewed on Oct 20, 2026

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Parco dei Principi Grand Hotel & SPA - Preferred Hotels & Resorts

Pinciano
Save 100% on your flight
$2,402
per person
Nov 20 - Nov 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9/10 Wonderful! (906 reviews)
Hotel Le Petit

Hotel Le Petit

Rome City Centre
$1,743
per person
Nov 21 - Nov 27
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9/10 Wonderful! (20 reviews)
Although the rooms are small compared to what we are used to, the hotel was beautiful and clean. The location is excellent with walking distance to the train station. It is conveniently located in city center making it very easy to walk to most of the iconic sites one would want to visit in Rome. There are many restaurants in shops nearby.

Reviewed on Oct 14, 2026

Where to stay in San Lorenzo

Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

Find hotels in Trastevere
The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

Find hotels in Trevi

San Lorenzo Hotel Deals

Líbere Rome San Lorenzo

Líbere Rome San Lorenzo

Via degli Ausoni, 33 Rome RM
Fully refundableReserve now, pay when you stay
$95 nightly
$118 total
Nov 9 - Nov 10
Total with taxes and fees
9.6/10 Exceptional! (56 reviews)
"We stayed at Hotel Liberté as a family of three during our trip to Rome. Overall, we had a nice stay and really liked the neighborhood. It has a young, hip and artsy feel, with lots of little bars, restaurants and about 15-20 mins walk on side street from Termini Station. If you enjoy that kind of ..."

Reviewed on Oct 3, 2026

Líbere Rome San Lorenzo
Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$68 nightly
$81 total
Oct 23 - Oct 24
Total with taxes and fees
8.2/10 Very Good! (1,912 reviews)
"Excepté le check-in Tout est bien"

Reviewed on Oct 17, 2026

Fabulous Village
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$153 nightly
$179 total
Nov 17 - Nov 18
Total with taxes and fees
8/10 Very Good! (2,159 reviews)
"Everything was as presented"

Reviewed on Oct 20, 2026

Best Western Hotel Rome Airport
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Stay near popular San Lorenzo attractions

Teatro Blackgull

Enjoy a performance at Teatro Blackgull, a theater with a story to tell in Rome. Visit the churches and notable monuments in this vibrant area.
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Lupa Romana

10.0/10 (1 review)
Enjoy an outing to Lupa Romana during your stay in Rome. Visit the notable monuments and stunning cathedral in this vibrant area.
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Wishlist Club

After visiting Wishlist Club, make a plan to see the other sights and activities in Rome. Make time to visit the cathedral and monuments while you're in the area.
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Pastificio Cerere

You can browse the exhibits at Pastificio Cerere, a museum with a story of its own, during your travels to Rome. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Studio d'Arte Contemporanea di Pino Casagrande

You can study the exhibits at Studio d'Arte Contemporanea di Pino Casagrande, a museum with a storied past, during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$130
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$54
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.