San Lorenzo Vacations from $1,033

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Your San Lorenzo Vacation

If you're wanting a food-lovers escape, our San Lorenzo vacation packages are what you need. Whether you want to experience its nightlife, bars and pubs or culture, this neighborhood has something on offer for everyone. Some top nearby attractions to visit during your trip to San Lorenzo include Roman Forum, Pantheon and Piazza Navona. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your budget or travel plans.

The Latest San Lorenzo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Room Mate Collection Mia, Rome Colosseum

Room Mate Collection Mia, Rome Colosseum

Rome City Centre
$1,033
per person
Jan 11 - Jan 18
found 12 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.4/10 Exceptional! (1,004 reviews)
Hotel Fiori

Hotel Fiori

Rome City Centre
$1,319
per person
Dec 31 - Jan 5
found 8 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (40 reviews)
Rebecca, who worked the front desk made the experience Great!

Reviewed on Oct 16, 2026

Hotel Maximus

Hotel Maximus

Rome City Centre
Save 100% on your flight
$2,065
per person
Nov 24 - Dec 1
found 10 hours ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.2/10 Wonderful! (69 reviews)
Great renovation of the facilities. Lovely room with private patio. Very well laid out and provisioned. Front desk staff was very helpful and friendly, anticipating needs and offering great help and suggestions. Cleaning staff and room service were exceptional - great service. You can tell when a facility is run well and the staff are happy and motivated - this was a wonderful stay in our visit to Rome. Location was great - near the Opera and great restaurants, walkable to Trevi, Pantheon, and Borghese. Thanks for a great time at your hotel!

Reviewed on Oct 20, 2026

Hotel Trame

Hotel Trame

Rome City Centre
$2,301
per person
Dec 25 - Dec 31
found 7 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Rome (FCO)
9.6/10 Exceptional! (29 reviews)
Great

Reviewed on Oct 20, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$4,253
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)

Where to stay in San Lorenzo

Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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San Lorenzo Hotel Deals

Líbere Rome San Lorenzo

Líbere Rome San Lorenzo

Via degli Ausoni, 33 Rome RM
Fully refundableReserve now, pay when you stay
$93 nightly
$116 total
Nov 9 - Nov 10
Total with taxes and fees
9.6/10 Exceptional! (56 reviews)
"We stayed at Hotel Liberté as a family of three during our trip to Rome. Overall, we had a nice stay and really liked the neighborhood. It has a young, hip and artsy feel, with lots of little bars, restaurants and about 15-20 mins walk on side street from Termini Station. If you enjoy that kind of ..."

Reviewed on Oct 3, 2026

Líbere Rome San Lorenzo
Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$68 nightly
$81 total
Oct 23 - Oct 24
Total with taxes and fees
8.2/10 Very Good! (1,913 reviews)
"Very good place for staining., reasonable price!"

Reviewed on Oct 20, 2026

Fabulous Village
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$153 nightly
$179 total
Nov 8 - Nov 9
Total with taxes and fees
Best Western Hotel Rome Airport
See all 16,605 properties in San Lorenzo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular San Lorenzo attractions

Pastificio Cerere

You can browse the exhibits at Pastificio Cerere, a museum with a story of its own, during your travels to Rome. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Teatro Blackgull

Enjoy a performance at Teatro Blackgull, a theater with a story to tell in Rome. Visit the churches and notable monuments in this vibrant area.
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Lupa Romana

10.0/10 (1 review)
Enjoy an outing to Lupa Romana during your stay in Rome. Visit the notable monuments and stunning cathedral in this vibrant area.
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Wishlist Club

After visiting Wishlist Club, make a plan to see the other sights and activities in Rome. Make time to visit the cathedral and monuments while you're in the area.
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Studio d'Arte Contemporanea di Pino Casagrande

You can study the exhibits at Studio d'Arte Contemporanea di Pino Casagrande, a museum with a storied past, during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$130
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$54
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.