San Lorenzo Vacations from $799

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Your San Lorenzo Vacation

If you're wanting a food-lovers escape, our San Lorenzo vacation packages are what you need. Whether you want to experience its nightlife, bars and pubs or culture, this neighborhood has something on offer for everyone. Some top nearby attractions to visit during your trip to San Lorenzo include Roman Forum, Pantheon and Piazza Navona. Expedia can help you turn your ideal San Lorenzo vacation into reality, whatever your budget or travel plans.

The Latest San Lorenzo Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Viminale View Hotel

Viminale View Hotel

Rome City Centre
$799
per person
Jan 13 - Jan 15
found 1 day ago
Roundtrip flight included
New York (LGA) to Rome (FCO)
9.2/10 Wonderful! (415 reviews)
The room was nothing special although clean and great air conditioning. The view however was fantastic! The fountain at the Piazza Del Viminale was beautiful. We also really enjoyed the breakfast and the location was perfect to get around to all our planned activities. Very walkable area with many restaurants.

Reviewed on Oct 14, 2026

Villa Pinciana

Villa Pinciana

Rome City Centre
$1,104
per person
Dec 6 - Dec 11
found 10 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.2/10 Wonderful! (529 reviews)
Rooms were clean, staff were very professional, I always look forward to the breakfasts while in Rome and this was no exception, nice variety and good quality. About a 15 minute walk from the train station.

Reviewed on Oct 12, 2026

U-Visionary Roma Hotel

U-Visionary Roma Hotel

Rome City Centre
Save 100% on your flight
$4,225
per person
Dec 26 - Jan 2
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (511 reviews)
We stayed for a mother-daughter trip to celebrate my daughter’s 16th birthday, and the staff made it unforgettable. I arranged a birthday package, but they went above and beyond with flowers, cakes, champagne, fruit, chocolates, and balloons—including giant “16” balloons! My daughter was absolutely delighted. As a mother traveling alone with her daughter, safety was a concern, but we felt safe and comfortable throughout our stay. The central location is perfect, the restaurant is excellent, and breakfast was wonderful. Most of all, the staff were truly amazing—so kind and thoughtful. Highly recommended!

Reviewed on Oct 17, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$4,139
per person
Dec 26 - Jan 2
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Rome (FCO)
9.4/10 Exceptional! (1,011 reviews)
Hotel Delle Civette

Hotel Delle Civette

Nomentano
$1,774
per person
Dec 26 - Jan 1
found 20 hours ago
Roundtrip flight included
New York (JFK) to Rome (FCO)
9.6/10 Exceptional! (323 reviews)
A beautiful building. Scrupulously clean. Staff top to bottom were lovely. Room very spacious with high ceilings and lovely windows with shutters and blackout curtains. Bathroom was great and had a powerful shower. Beds and pillows were very comfortable for us…firm but not hard. 2 wardrobes with drawers and bedside tables also had drawers. Safe in the wardrobe. There’s a heating radiator and air con in the room. Convenient location. 10 mins walk to Bologna metro. In total 30 mins to most landmarks (some less). We also used the buses frequently. Excellent bus service in Rome. Breakfast…lovely staff…but quite basic. A lovely location and quiet. Wouldn’t hesitate to recommend. Thank-you for a lovely stay.

Reviewed on Oct 13, 2026

Where to stay in San Lorenzo

Find the best San Lorenzo areas and neighborhoods for the activities you enjoy most. Learn more about San Lorenzo
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

Find hotels in Rome Historic Centre
A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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San Lorenzo Hotel Deals

Líbere Rome San Lorenzo

Líbere Rome San Lorenzo

Via degli Ausoni, 33 Rome RM
Fully refundableReserve now, pay when you stay
$92 nightly
$115 total
Nov 9 - Nov 10
Total with taxes and fees
9.6/10 Exceptional! (54 reviews)
"We stayed at Hotel Liberté as a family of three during our trip to Rome. Overall, we had a nice stay and really liked the neighborhood. It has a young, hip and artsy feel, with lots of little bars, restaurants and about 15-20 mins walk on side street from Termini Station. If you enjoy that kind of ..."

Reviewed on Oct 3, 2026

Líbere Rome San Lorenzo
Fabulous Village

Fabulous Village

Via Di Malafede 225 Rome RM
$68 nightly
$81 total
Oct 23 - Oct 24
Total with taxes and fees
8.2/10 Very Good! (1,911 reviews)
"Excepté le check-in Tout est bien"

Reviewed on Oct 17, 2026

Fabulous Village
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

Via Portuense, 2465 Fiumicino RM
Fully refundableReserve now, pay when you stay
$153 nightly
$180 total
Nov 1 - Nov 2
Total with taxes and fees
8/10 Very Good! (2,151 reviews)
"Airport shuttle bus is very useful. The hotel is a bit stark but probably better in the summer. Restaurant better than many hotel restaurants. The soap dispensers were very difficult to use and one not usable at all."

Reviewed on Oct 18, 2026

Best Western Hotel Rome Airport
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Stay near popular San Lorenzo attractions

Teatro Blackgull

Enjoy a performance at Teatro Blackgull, a theater with a story to tell in Rome. Visit the churches and notable monuments in this vibrant area.
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Lupa Romana

10.0/10 (1 review)
Enjoy an outing to Lupa Romana during your stay in Rome. Visit the notable monuments and stunning cathedral in this vibrant area.
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Wishlist Club

After visiting Wishlist Club, make a plan to see the other sights and activities in Rome. Make time to visit the cathedral and monuments while you're in the area.
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Pastificio Cerere

You can browse the exhibits at Pastificio Cerere, a museum with a story of its own, during your travels to Rome. Discover the acclaimed art scene and stunning cathedral in this vibrant area.
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Studio d'Arte Contemporanea di Pino Casagrande

You can study the exhibits at Studio d'Arte Contemporanea di Pino Casagrande, a museum with a storied past, during your trip to Rome. Experience the fascinating museums and acclaimed art scene in this vibrant area.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$30
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Skip-the-line: Colosseum & Forum Tour with Special Gladiator’s Gate & Arena Floor Access

Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group

$130
per adult
94% of travellers recommend
Gladiator’s Gate:Special Access Colosseum Tour & Arena Floor in Small Group
Pasta-Making Class: Cook, Dine & Drink With A Local Chef

Pasta-Making Class: Cook, Dine & Drink With A Local Chef

$54
per adult
100% of travellers recommend
Pasta-Making Class: Cook, Dine & Drink With A Local Chef
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.