Title: San Luis Rio Colorado Vacation Rentals from $106: Search Short-Term Rentals | Expedia.com

[San Luis Rio Colorado Travel Guide](https://expedia.com/San-Luis-Rio-Colorado.dx10155)[Hotels in San Luis Rio Colorado](https://expedia.com/San-Luis-Rio-Colorado-Hotels.d10155.Travel-Guide-Hotels)[Flights to San Luis Rio Colorado](https://expedia.com/Cheap-Flights-To-San-Luis-Rio-Colorado.d10155.Travel-Guide-Flights)[Car Rentals in San Luis Rio Colorado](https://expedia.com/Car-Rentals-In-San-Luis-Rio-Colorado.d10155.Car-Rental-Guide)[San Luis Rio Colorado Vacation Packages](https://expedia.com/San-Luis-Rio-Colorado.d10155.Destination-Travel-Guides)

![Afternoon sun shines on the historic downtown church of central San Luis Río Colorado, Sonora, Mexico.](https://images.trvl-media.com/place/10155/e355d5c8-a23e-4e13-af13-39ea629172f2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/10155/e355d5c8-a23e-4e13-af13-39ea629172f2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=10155&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=10155&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=10155&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=10155&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for San Luis Rio Colorado vacation rentals

![Exterior detail](https://images.trvl-media.com/lodging/120000000/119670000/119661700/119661613/925c6f71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/120000000/119670000/119661700/119661613/7095bdbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/120000000/119670000/119661700/119661613/66007295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/120000000/119670000/119661700/119661613/1563e05a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Casita, you will feel right at home!

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h119661613.Hotel-Information)

San Luis Río Colorado

10/10

Exceptional

(1 review)

"It was a nice cozy little house that had everything you could need. 10/10 "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jillia C.

$92 nightly

$106 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h119661613.Hotel-Information)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101950000/101945900/101945813/2da7f286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/102000000/101950000/101945900/101945813/bcd82905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101950000/101945900/101945813/3782a8c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/102000000/101950000/101945900/101945813/c17c3c97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Increíble Moderno Espacio Único

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Increible-Moderno-Espacio-Unico.h101945813.Hotel-Information)

San Luis Río Colorado

$222 nightly

$258 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Increible-Moderno-Espacio-Unico.h101945813.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/112000000/111260000/111254200/111254179/2257ca48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111260000/111254200/111254179/2366d7aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111260000/111254200/111254179/f7ac331b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111260000/111254200/111254179/61aa2c25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### COMFORT, LUXURY RELAX

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h111254179.Hotel-Information)

San Luis Río Colorado

4.0/10

(1 review)

"Esta en un Barrio no deseable. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Enrique J.

$148 nightly

$170 total

Feb 10 - Feb 11

Total with taxes and fees

[](https://www.expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h111254179.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-23&endDate=2026-02-24&regionId=10155&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=San+Luis+Rio+Colorado%2C+Sonora%2C+Mexico&regionId=10155&latLong=32.451889%2C-114.771713&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=San+Luis+Rio+Colorado%2C+Sonora%2C+Mexico&regionId=10155&latLong=32.451889%2C-114.771713&adults=2&startDate=2026-05-10&d1=2026-05-10&endDate=2026-05-13&d2=2026-05-13&lodging=APARTMENT)

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## Top San Luis Rio Colorado Hotel Reviews

![California Comfort and Suites](https://images.trvl-media.com/lodging/23000000/22190000/22187900/22187853/726022c6_y.jpg)

### California Comfort and Suites

10/10 Excellent

"Clean room, safe and secure, nice parking. Good customer service"

[](https://expedia.com/Los-Algodones-Hotels-California-Comfort-And-Suites.h22187853.Hotel-Information)

![Hotel Araiza San Luis](https://images.trvl-media.com/lodging/17000000/16720000/16713300/16713210/b10acdb4_y.jpg)

### Hotel Araiza San Luis

10/10 Excellent

"Yes"

[](https://expedia.com/San-Luis-Rio-Colorado-Hotels-Hotel-Araiza-San-Luis.h16713210.Hotel-Information)

![653 Hotel](https://images.trvl-media.com/lodging/97000000/96720000/96711600/96711564/c2e3207e_y.jpg)

### 653 Hotel

10/10 Excellent

"Nice clean modern hotel with fridge. Friendly staff "

[](https://expedia.com/San-Luis-Rio-Colorado-Hotels-653-Hotel.h96711564.Hotel-Information)

![The Casita, you will feel right at home!](https://images.trvl-media.com/lodging/120000000/119670000/119661700/119661613/f97894bc_y.jpg)

### The Casita, you will feel right at home!

10/10 Excellent

"It was a nice cozy little house that had everything you could need. 10/10 "

[](https://expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h119661613.Hotel-Information)

![Hotel San Angel & Spa](https://images.trvl-media.com/lodging/107000000/106050000/106048600/106048568/9f44fc0d_y.jpg)

### Hotel San Angel & Spa

10/10 Excellent

"The hotel was nice as well as the staff "

[](https://expedia.com/San-Luis-Rio-Colorado-Hotels-Hotel-San-Angel-Spa.h106048568.Hotel-Information)

![COMFORT, LUXURY RELAX](https://images.trvl-media.com/lodging/112000000/111260000/111254200/111254179/5d58b421_y.jpg)

### COMFORT, LUXURY RELAX

4/10 Poor

"Esta en un Barrio no deseable. "

[](https://expedia.com/San-Luis-Rio-Colorado-Hotels-Vrbo-Property.h111254179.Hotel-Information)

## Find out more about San Luis Rio Colorado

**Everything you need to know about San Luis Rio Colorado vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Luis Rio Colorado vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Luis Rio Colorado vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**San Luis Rio Colorado vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in San Luis Rio Colorado. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Luis Rio Colorado in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $106 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on San Luis Rio Colorado rentals**

At Expedia, we put the best San Luis Rio Colorado vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top San Luis Rio Colorado rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Luis Rio Colorado vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Luis Rio Colorado. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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## Frequently asked questions

### Are there vacation rentals in San Luis Rio Colorado?

### What are some of the best vacation home rentals that San Luis Rio Colorado has to offer?

### How many vacation rentals are there in San Luis Rio Colorado?

### What can I see and do in San Luis Rio Colorado?

### What are vacation rentals like in San Luis Rio Colorado?

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