San Marco Vacations from $738

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Your San Marco Vacation

Lock in a San Marco vacation package and get set to experience all this lively city has to offer. Consider staying in the neighborhood of San Biagio della Valle, which is great for views, nature and history. You'll want to sightsee during your trip to San Marco. Carve out some time for big-name attractions such as Piazza IV Novembre, Rocca Paolina and Basilica San Pietro. Your ultimate San Marco vacation is a couple of clicks away. Explore airfares, hotels and more on Expedia for an adventure that's tailored to suit your travel style.

The Latest San Marco vacation packages

Price found within the past 48 hours. Click for updated prices.
Lo Spedalicchio
Hotel Sorella Luna
Il Palazzo
Locanda della Posta Boutique Hotel
Visionair Suites
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Discover the most popular places to visit in San Marco

What to do in San Marco

San Marco Hotel Deals

TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

4 out of 5
Viale Patrono d'Italia 70, Santa Maria degli Angeli, Assisi, PG
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Nov 2 to Nov 3
$113 total
Nov 2 - Nov 3
Total with taxes and fees
9/10 Wonderful! (589 reviews)
Excellent stay at Assisi
"Excellent stay at Assisi. The hotel was recently renovated and provided all the amenities we expected. The breakfast buffet was really good. The room was clean and spacious. The staff were friendly and responsive. Highly recommended."

Reviewed on Oct 5, 2025

TH Assisi - Hotel Cenacolo
Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6, Cortona, AR
Fully refundableReserve now, pay when you stay
$620 nightly
The price is $691 total per night from Oct 13 to Oct 14
$691 total
Oct 13 - Oct 14
Total with taxes and fees
9.6/10 Exceptional! (223 reviews)
"I stayed at Villa di Piazzano for two nights and overall had a lovely experience. The check-in process was seamless, and the staff were warm, professional, and very attentive, which set a great tone from the start. The property itself is absolutely gorgeous, with beautiful grounds and a peaceful ..."

Reviewed on Sep 23, 2025

Villa di Piazzano - Small Luxury Hotel of the World
BV Grand Hotel Assisi

BV Grand Hotel Assisi

4 out of 5
Via Giovanni Renzi No 2, Assisi, PG
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $111 total per night from Oct 29 to Oct 30
$111 total
Oct 29 - Oct 30
Total with taxes and fees
8.4/10 Very Good! (299 reviews)
Good Memories
"Nice big breakfast. Lots of patios to enjoy the great views. Very good front desk service - thanks Simone!"

Reviewed on Sep 17, 2025

BV Grand Hotel Assisi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

San Marco Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Sant Egidio Airport (PEG)
Max Temp Winter
50ºF
Max Temp Summer
85ºF
Top Sights
Cathedral of Saint Lorenzo, Citta della Domenica and Castello di Ramazzano

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Frequently asked questions

How much does a San Marco vacation package cost?
Offering excellent value package deals from $738 on Expedia, you'll be thrilled with how little a vacation to San Marco costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to San Marco?
November, December and January are great times to search for cheap San Marco vacation packages. Traveling in less busy periods means you'll typically find lower prices on hotels and flights.
How many days is enough for San Marco?
The ideal length for your San Marco vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you enough time to tick off all the leading sights and explore some hidden treasures along the way.
How to find the best San Marco package deals?
Begin your search for a San Marco package deal by entering your travel dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect San Marco package deal straight away, simply play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your San Marco escape off to a flying start.
Is it cheaper to book a San Marco vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll generally score a better deal than booking each component individually. And you'll still have the freedom to create a personalized San Marco vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to San Marco?
If you've got your San Marco travel dates locked in, book as soon as you can to score some terrific deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later San Marco vacation packages?
Your San Marco trip is meant to be a relaxing escape from your busy life, not a source of money-related stress. So to give you that extra flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.