San Marco Vacations from $425

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Your San Marco Vacation

Lock in a San Marco vacation package and get set to experience all this lively city has to offer. Consider staying in the neighborhood of San Biagio della Valle, which is great for views, nature and history. You'll want to sightsee during your trip to San Marco. Carve out some time for big-name attractions such as Piazza IV Novembre, Rocca Paolina and Basilica San Pietro. Your ultimate San Marco vacation is a couple of clicks away. Explore airfares, hotels and more on Expedia for an adventure that's tailored to suit your travel style.

The Latest San Marco vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Villa Pina
Fortino Napoleonico
V Hotel
Hotel Fiorella
Pineta Hotel
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San Marco Hotel Deals

Villa di Piazzano - Small Luxury Hotel of the World

Villa di Piazzano - Small Luxury Hotel of the World

5 out of 5
Localita Piazzano, C.P. 6 Cortona AR
$639 nightly
The price is $712 total per night from Apr 14 to Apr 15
$712 total
Apr 14 - Apr 15
Total with taxes and fees
9.8/10 Exceptional! (229 reviews)
We really enjoyed the hotel, very clean, good atmosphere!!!

Reviewed on Apr 10, 2026

Villa di Piazzano - Small Luxury Hotel of the World
Hotel Sangallo Palace

Hotel Sangallo Palace

4 out of 5
Via L Masi 9 Perugia PG
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $171 total per night from Apr 26 to Apr 27
$171 total
Apr 26 - Apr 27
Total with taxes and fees
8.8/10 Excellent! (629 reviews)
This is a very nice full service hotel in good location for taking escalators up to the old city. Clean room. Great breakfast.

Reviewed on Mar 10, 2026

Hotel Sangallo Palace
Giotto Hotel & Spa

Giotto Hotel & Spa

4 out of 5
Via Fontebella 41 Assisi PG
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $150 total per night from Apr 13 to Apr 14
$150 total
Apr 13 - Apr 14
Total with taxes and fees
8.8/10 Excellent! (786 reviews)
Beautiful hotel with wonderful views. Fresh squeezed blood orange juice at breakfast is a must.

Reviewed on Apr 10, 2026

Giotto Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Marco Vacation Packages

San Marco Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Sant Egidio Airport (PEG)
Max Temp Winter
50ºF
Max Temp Summer
85ºF
Top Sights
Cathedral of Saint Lorenzo, Citta della Domenica and Castello di Ramazzano

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Frequently asked questions

How much does a San Marco vacation package cost?
Offering excellent value package deals from $425 on Expedia, you'll be thrilled with how little a vacation to San Marco costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to San Marco?
November, December and January are great times to search for cheap San Marco vacation packages. Traveling in less busy periods means you'll typically find lower prices on hotels and flights.
How many days is enough for San Marco?
The ideal length for your San Marco vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you enough time to tick off all the leading sights and explore some hidden treasures along the way.
How to find the best San Marco package deals?
Begin your search for a San Marco package deal by entering your travel dates and destination under our "Packages" tab. Then add a few filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the perfect San Marco package deal straight away, simply play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your San Marco escape off to a flying start.
Is it cheaper to book a San Marco vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll generally score a better deal than booking each component individually. And you'll still have the freedom to create a personalized San Marco vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to San Marco?
If you've got your San Marco travel dates locked in, book as soon as you can to score some terrific deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later San Marco vacation packages?
Your San Marco trip is meant to be a relaxing escape from your busy life, not a source of money-related stress. So to give you that extra flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.