San Sisto Vacations from $1,488
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your San Sisto Vacation
An easy way to experience this interesting city is with a customized San Sisto vacation package. Stay in the neighborhood of San Biagio della Valle, which is good for views, nature and history or go someplace else — our package deals are all about you. Make your trip to San Sisto even more fun by including some sightseeing. Piazza IV Novembre, Rocca Paolina and Basilica San Pietro are some of the major attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to San Sisto to suit your style of travel, whatever that may be.
The Latest San Sisto vacation packages
Price found within the past 48 hours. Click for updated prices.
Borgo Tre Vaselle
$1,516
per person
Nov 15 - Nov 22
found 8 hours ago
Roundtrip flight included
Philadelphia (PHL) to Perugia San Francesco d'Assisi – Umbria Intl. Airport (PEG)
10/10 Exceptional! (1 review)
Amazing spot! Much better than the pictures. Amazing food, quiet and relaxing place.
Reviewed on Oct 9, 2026
Stay near popular San Sisto attractions
Perugina Chocolate Factory
8.6/10 (58 reviews)
Enjoy an outing to Perugina Chocolate Factory during your stay in San Sisto. Discover the area's jazz scene and cathedral.
What to do in San Sisto
Perugia: Old Town Walking Tour, Piazza IV Novembre
$34
per adult
Rome Day Tour to Assisi, Civita di Bagnoregio & Orvieto
$113
per adult
88% of travellers recommend
Pic nic Deluxe Assisi and wine tasting 5 wines
$51
per adult
San Sisto Hotel Deals
Villa di Piazzano - Small Luxury Hotel of the World
Localita Piazzano, C.P. 6 Cortona AR
$625 nightly
$696 total
Oct 27 - Oct 28
Total with taxes and fees
9.8/10 Exceptional! (254 reviews)
"Stunning property; a real representation of Tuscany with the long driveway of tall trees; staff was amazing; food was excellent; gardens, picturesque! We would highly recommend! Overall amazing !!!"
Reviewed on Oct 5, 2026
La Meridiana Bleisure Hotel
42 del Discobolo St. Perugia PG
Fully refundableReserve now, pay when you stay
$91 nightly
$107 total
Nov 8 - Nov 9
Total with taxes and fees
Giotto Hotel & Spa
Via Fontebella 41 Assisi PG
Fully refundableReserve now, pay when you stay
$86 nightly
$103 total
Nov 10 - Nov 11
Total with taxes and fees
9/10 Wonderful! (842 reviews)
"The location was amazing , the view is beautiful specially at evening time. The staff very friendly, helpful and welcoming. I totally recommend the hotel .. for sure will be my choice on my next visit to Assisi"
Reviewed on Oct 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best San Sisto Vacation Packages
San Sisto Essential Information
Language | Italian |
|---|---|
Currency | Euros |
Local Welcome | Ciao |
Local Goodbye | Ciao |
Closest Airport | Sant Egidio Airport (PEG) |
Top Sights | Cathedral of Saint Lorenzo, Citta della Domenica and Castello di Ramazzano |
More vacations you might like
Frequently asked questions
How much does a San Sisto vacation package cost?
You can snap up a vacation package to this destination from $1,488 on Expedia. However, how much your vacation to San Sisto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to San Sisto?
November, December and January are the best times to look for cheap San Sisto vacation packages. Traveling in less busy periods means you'll typically find lower prices on accommodations and flights.
How many days is enough for San Sisto?
With a well-planned itinerary, you can easily tick off the most popular San Sisto sights in a handful of days. But if you want to venture off the beaten track or go on day tours, think about booking your San Sisto vacation for longer.
How to find the best San Sisto package deals?
Use Expedia's handy filters to help you find some great San Sisto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or browse for San Sisto package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a San Sisto vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored San Sisto vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to San Sisto?
If you're planning a spur-of-the-moment San Sisto getaway, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to San Sisto?
- Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to visit San Sisto.
- Set your budget: Consider costs such as flights, food and transportation when working out how much to put aside for your trip to San Sisto. Then, select a hotel that matches your budget, whether that's a low-cost stay or a swankier getaway.
- Organize your San Sisto getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with your group to plan an unforgettable trip to San Sisto together.
- Set the duration of your trip: Start by making a list of all the sights and activities you'd like to get to in San Sisto. Then, estimate how long you'll need at each, as well as any travel time.
- Combine your hotel and flights: Awesome destination, check. Length of stay, check. Now all that's left is to find a San Sisto vacation package that brings all your bookings together.
- Book activities and experiences ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on San Sisto's highlights. Find all the exciting things to do in San Sisto in San Sisto with our dedicated activity guide.
Does Expedia offer Book Now, Pay Later San Sisto vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your San Sisto break across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.
Explore a world of travel with Expedia
- Winery Hotels in Umbria
- Ellera Hotels
- Hotel Wedding Venues Hotels in Perugia
- B&B in Umbria
- Cottages in Umbria
- B&B in Perugia
- Cheap Hotels in Perugia
- Hotels with Free Parking in Perugia
- Hotels near Basilica San Pietro
- B&B in Ferro di Cavallo
- Apartments in Perugia
- Umbria Hotels
- Old Town Perugia Hotels
- Villas in Umbria
- Gay friendly Hotels in Perugia
- Luxury Hotels in Umbria
- Family Hotels in Umbria
- Hotels near Perugina Chocolate Factory
- Villas in Perugia
- Hotels near Collegio del Cambio
- Castles in Umbria
- Cheap Hotels in Umbria
- Hotels near National Archaeological Museum of Umbria
- Hotels with an Indoor Pool in Umbria
- All-Inclusive Resorts in Umbria
- Luxury Hotels in Perugia
- Hotels near Perugia Station
- Hotels near Corso Vannucci
- Hotels & Resorts for Couples in Umbria
- Nh Hotels in Perugia
- Vacation Homes in Umbria
- Hotels near Santa Maria della Misericordia Hospital
- Adults Only Resorts & in Umbria
- Resorts & Hotels with Spas in Umbria
- Hotels with Tennis Courts in Umbria
- Perugia Hotels
- 4 Star Hotels in Perugia
- Hotel Wedding Venues Hotels in Umbria
- Farmstay in Umbria
- Abbey of San Pietro
- Collegio del Cambio
- Cathedral of Saint Lorenzo
- Perugina Chocolate Factory
- Santa Maria della Misericordia Hospital
- House Museum of Oddi Marini Clarelli
- Fontana Maggiore
- Visit Ferro di Cavallo
- Arco Etrusco
- Visit San Sisto
- Perugia Vacations
- Hall of Notaries
- Renato Curi Stadium
- Corso Vannucci
- Cassero di Porta Sant’Angelo
- Where to stay in Perugia
- Visit Olmo
- Visit Boneggio
- Umbria Vacations
- Solomeo Vacations
- Piazza Matteotti-Perugia
- Piazza IV Novembre
- University of Perugia
- Corciano Vacations
- Basilica di San Domenico
- Visit Perugia
- Nuova chiesa di San Paolo a Foligno
- Chiesa del Gesu
- University for Foreigners of Perugia
- National Gallery of Umbria
- Rocca Paolina
- Visit Province of Perugia
- Church of Santa Giuliana
- Province of Perugia Vacations
- Roman Aqueduct
- Basilica San Pietro
- Visit Umbria
- Church of Sant'Ercolano
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
