San Sisto Vacations from $1,868

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Your San Sisto Vacation

An easy way to experience this interesting city is with a customized San Sisto vacation package. Stay in the neighborhood of San Biagio della Valle, which is good for views, nature and history or go someplace else — our package deals are all about you. Make your trip to San Sisto even more fun by including some sightseeing. Piazza IV Novembre, Rocca Paolina and Basilica San Pietro are some of the major attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to San Sisto to suit your style of travel, whatever that may be.

The Latest San Sisto vacation packages

Price found within the past 48 hours. Click for updated prices.
Visionair Suites

Visionair Suites

4 out of 5
Price was $1,913, price is now $1,868 per person
$1,868
per person
Jan 19 - Jan 21
found 17 hours ago
Roundtrip flight included
Baltimore (BWI) to Ancona (AOI)
19.6/10 Exceptional! (28 reviews)
The location is perfect with beach, bars, restaurant and shopping all in easy walking distance. The view from the hotel are immaculate up along the entire coast. The staff were helpful, friendly and proactive. We accidentally left our laptop and iPads in the room safe on check out but we received a call to let us know this had happened and arrangement were made for us to pick them up conveniently. The hotel itself is virtually brand new and is excellent value for money. Would not hesitate to stay there again

Reviewed on Sep 21, 2025

UNAHOTELS Villa dei Platani Foligno

UNAHOTELS Villa dei Platani Foligno

4 out of 5
Price was $1,992, price is now $1,956 per person
$1,956
per person
Jan 19 - Jan 21
found 17 hours ago
Roundtrip flight included
Baltimore (BWI) to Ancona (AOI)
18.4/10 Exceptional! (84 reviews)
View Place & Spa

View Place & Spa

5 out of 5
Price was $1,944, price is now $1,919 per person
$1,919
per person
Jan 19 - Jan 21
found 17 hours ago
Roundtrip flight included
Baltimore (BWI) to Ancona (AOI)
9.6/10 Exceptional! (33 reviews)
Un nuovissimo hotel

Reviewed on Jul 6, 2025

Raffaello Hotel

Raffaello Hotel

4 out of 5
Price was $1,925, price is now $1,903 per person
$1,903
per person
Jan 19 - Jan 21
found 17 hours ago
Roundtrip flight included
Baltimore (BWI) to Ancona (AOI)
17.6/10 Exceptional! (107 reviews)
The front desk was extremely helpful and kind

Reviewed on Nov 12, 2023

EGO Hotel

EGO Hotel

4 out of 5
Price was $1,998, price is now $1,978 per person
$1,978
per person
Jan 19 - Jan 21
found 17 hours ago
Roundtrip flight included
Baltimore (BWI) to Ancona (AOI)
19.2/10 Exceptional! (895 reviews)
Always excellent. Staff are wonderful and authentically kind and helpful. Spa perfection in stress management! Area steeped in history. We love it here and have been returning for years. Highly recommended.

Reviewed on Nov 13, 2025

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Discover the most popular places to visit in San Sisto

Piazza IV Novembre which includes a city and heritage architecture as well as a small group of people

Piazza IV Novembre

4.5/5(39 reviews)

Located in the heart of Perugia, this small square is surrounded by some of the town’s most impressive landmarks.

Piazza IV Novembre
Perugia showing a city

Corso Vannucci

5/5(2 reviews)

Learn about the local history of Perugia with a stop at Corso Vannucci. You can enjoy the bars while in the area.

Corso Vannucci
Rocca Paolina showing heritage architecture

Rocca Paolina

5/5(11 reviews)

Explore a maze of tunnels and alleys, and visit markets, events and exhibitions in the foundations of a 16th-century fortress.

Rocca Paolina

What to do in San Sisto

Perugia: Old Town Walking Tour, Piazza IV Novembre

Perugia: Old Town Walking Tour, Piazza IV Novembre

$35
per adult
Perugia: Old Town Walking Tour, Piazza IV Novembre
Truffle Hunting Experience in Assisi

Truffle Hunting Experience in Assisi

$64
per adult
Truffle Hunting Experience in Assisi
Umbria: guided tour to traditional oil mill + tasting

Umbria: guided tour to traditional oil mill + tasting

$16
per adult
Umbria: guided tour to traditional oil mill + tasting
See all activities in San Sisto

San Sisto Hotel Deals

Giotto Hotel & Spa

Giotto Hotel & Spa

4 out of 5
Via Fontebella 41 Assisi PG
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $107 total per night from Nov 26 to Nov 27
$107 total
Nov 26 - Nov 27
Total with taxes and fees
8.8/10 Excellent! (749 reviews)
The room was small but very clean. An issue we had with the bed was quickly taken care of. The breakfast and whole atmosphere in this beautiful setting was wonderful. We would stay here again!

Reviewed on Nov 12, 2025

Giotto Hotel & Spa
TH Assisi - Hotel Cenacolo

TH Assisi - Hotel Cenacolo

4 out of 5
Viale Patrono d'Italia 70 Assisi PG
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $96 total per night from Dec 16 to Dec 17
$96 total
Dec 16 - Dec 17
Total with taxes and fees
9/10 Wonderful! (595 reviews)
Nice place to stay

Reviewed on Oct 15, 2025

TH Assisi - Hotel Cenacolo
La Meridiana Bleisure Hotel

La Meridiana Bleisure Hotel

4 out of 5
42 del Discobolo St. Perugia PG
Fully refundableReserve now, pay when you stay
$84 nightly
The price is $97 total per night from Dec 17 to Dec 18
$97 total
Dec 17 - Dec 18
Total with taxes and fees
8.4/10 Very Good! (319 reviews)
The best hotel and seevices u can ever have. Definitely recommend!!

Reviewed on Oct 16, 2025

La Meridiana Bleisure Hotel
See all 3,382 properties in San Sisto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Sisto Vacation Packages

San Sisto Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Sant Egidio Airport (PEG)
Top Sights
Cathedral of Saint Lorenzo, Citta della Domenica and Castello di Ramazzano

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Frequently asked questions

How much does a San Sisto vacation package cost?
You can snap up a vacation package to this destination from $1,868 on Expedia. However, how much your vacation to San Sisto costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to San Sisto?
November, December and January are the best times to look for cheap San Sisto vacation packages. Traveling in less busy periods means you'll typically find lower prices on accommodations and flights.
How many days is enough for San Sisto?
With a well-planned itinerary, you can easily tick off the most popular San Sisto sights in a handful of days. But if you want to venture off the beaten track or go on day tours, think about booking your San Sisto vacation for longer.
How to find the best San Sisto package deals?
Use Expedia's handy filters to help you find some great San Sisto package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or browse for San Sisto package deals in the off-season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
Is it cheaper to book a San Sisto vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component separately. And you'll still get the flexibility to create a tailored San Sisto vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to San Sisto?
If you're planning a spur-of-the-moment San Sisto getaway, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to San Sisto?

  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to visit San Sisto.
  2. Set your budget: Consider costs such as flights, food and transportation when working out how much to put aside for your trip to San Sisto. Then, select a hotel that matches your budget, whether that's a low-cost stay or a swankier getaway.
  3. Organize your San Sisto getaway with Expedia's trip planning tool: Search for and book hotels and activities all in one place. You can also collaborate with your group to plan an unforgettable trip to San Sisto together.
  4. Set the duration of your trip: Start by making a list of all the sights and activities you'd like to get to in San Sisto. Then, estimate how long you'll need at each, as well as any travel time.
  5. Combine your hotel and flights: Awesome destination, check. Length of stay, check. Now all that's left is to find a San Sisto vacation package that brings all your bookings together.
  6. Book activities and experiences ahead of time: Whether it's a ticket to a major attraction or a day trip, you won't have to worry about missing out on San Sisto's highlights. Find all the exciting things to do in San Sisto in San Sisto with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later San Sisto vacation packages?
If you're anything like us, you love discovering new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your San Sisto break across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure cheap vacation packages with payment plans as soon as you see them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.