Title: Sant'Antonio Vacation Packages 2026 from $1,166 | Expedia.com [Sant'Antonio Travel Guide](https://expedia.com/SantAntonio.dx6270759)[Hotels in Sant'Antonio](https://expedia.com/SantAntonio-Hotels.d6270759.Travel-Guide-Hotels)[Vacation Rentals in Sant'Antonio](https://expedia.com/SantAntonio-Vacation-Rentals.d6270759.Travel-Guide-VacationRentals)[Flights to Sant'Antonio](https://expedia.com/Cheap-Flights-To-SantAntonio.d6270759.Travel-Guide-Flights)[Car Rentals in Sant'Antonio](https://expedia.com/Car-Rentals-In-SantAntonio.d6270759.Car-Rental-Guide) ![](https://images.trvl-media.com/place/553248633938945235/f321690c-ea81-439e-8d85-51c90de9ab7f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Sant'Antonio Vacations from $1,166 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your SantAntonio Vacation Reserve a SantAntonio vacation package and prepare to experience all this lively city has to offer. Consider staying in the neighborhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to [Cathedral of Pisa](https://www.expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction), [Knights Square](https://www.expedia.com/Knights-Square-Pisa-City-Centre.d6073862.Vacation-Attraction) and [Pisa Baptistry](https://www.expedia.com/Pisa-Baptistry-Pisa-City-Centre.d6073896.Vacation-Attraction), some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio vacation on Expedia. ## The Latest Sant'Antonio vacation packages Price found within the past 48 hours. Click for updated prices. ![Eurostars Florence Boutique](https://images.trvl-media.com/lodging/2000000/1170000/1167000/1166901/88283612_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Eurostars Florence Boutique Historic Centre of Florence Save 100% on your flight $1,166 per person May 13 - May 18 found 1 day ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Florence (FLR) 8.6/10 Excellent! (483 reviews) The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants. Reviewed on Dec 13, 2025 ![Relais Uffizi, Tailor made Hotel](https://images.trvl-media.com/lodging/3000000/2550000/2542800/2542717/3e59e5ae_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais Uffizi, Tailor made Hotel Historic Centre of Florence Save 100% on your flight $2,122 per person May 13 - May 19 found 1 day ago Roundtrip non-stop flight included New York (NYC) to Florence (FLR) 9.4/10 Exceptional! (120 reviews) The room was stunning, it was large, the bed was comfy and the design was unique. Staff were very friendly and helpful. Reviewed on Feb 26, 2026 ![Hotel La Scaletta Al Ponte Vecchio](https://images.trvl-media.com/lodging/2000000/1610000/1604300/1604285/d1c916cb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel La Scaletta Al Ponte Vecchio Historic Centre of Florence Save 100% on your flight $1,509 per person May 13 - May 18 found 1 day ago Roundtrip non-stop flight included Newark Liberty Intl. Airport (EWR) to Florence (FLR) 8.8/10 Excellent! (965 reviews) The staff at breakfast prepare plain scrambled eggs for our 7 month old son and were very sweet! This our second time staying here and we absolutely love the hotel. Location, views, comfort. 10/10! Reviewed on Feb 28, 2026 ![Hotel Alessandra](https://images.trvl-media.com/lodging/2000000/1790000/1780300/1780229/4549f56f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Alessandra Historic Centre of Florence Save 100% on your flight $1,314 per person May 20 - May 26 found 1 day ago Roundtrip non-stop flight included New York (NYC) to Florence (FLR) 9.2/10 Wonderful! (849 reviews) Clean room, amazing staff, location is great Reviewed on Feb 2, 2026 ![Hotel Santa Maria Novella](https://images.trvl-media.com/lodging/1000000/930000/920500/920451/7b96b723_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Santa Maria Novella Historic Centre of Florence Save 100% on your flight $1,924 per person May 13 - May 19 found 1 day ago Roundtrip non-stop flight included New York (NYC) to Florence (FLR) 9.6/10 Exceptional! (1,000 reviews) Absolute perfection!! Reviewed on Mar 3, 2026 Don't see what you're looking for? See all available trips from Columbus to Sant'Antonio [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-03/2026-04-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PSA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6270759) ### Discover the most popular places to visit in Sant'Antonio ![Leaning Tower which includes a monument, a city and a church or cathedral](https://images.trvl-media.com/place/6270669/ad1bc6f8-1f44-482a-8858-2e921455b806.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Leaning Tower 5/5(217 reviews) The jewel in Pisa’s crown is this iconic cylindrical bell tower, which has become world-famous because of its bizarre angle. [](https://expedia.com/Leaning-Tower-Pisa-City-Centre.d6270669.Vacation-Attraction) ![Leaning Tower showing heritage architecture, a monument and land animals](https://images.trvl-media.com/place/6073918/658143fb-f5f7-45a8-a980-1b03332e82c0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza dei Miracoli 4.5/5(86 reviews) The Leaning Tower of Pisa makes this walled square the most photographed square in Pisa, but its other grand structures are also worth capturing. [](https://expedia.com/Piazza-Dei-Miracoli-Pisa-City-Centre.d6073918.Vacation-Attraction) ![Cathedral of Pisa which includes a monument, a church or cathedral and heritage elements](https://images.trvl-media.com/place/6073838/666c72a9-553f-45c9-adc8-7845c163cdab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cathedral of Pisa 4.5/5(196 reviews) At the heart of Piazza dei Miracoli lies an impressive example of Romanesque architecture, one of the most sacred sites in Italy. [](https://expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction) ### What to do in Sant'Antonio ![Lucca : audio-guided tour of the historic center](https://mediaim.expedia.com/localexpert/51101571/5d3ed7e6-2c4e-4afc-be77-e7d1cf7ffdfc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lucca : audio-guided tour of the historic center $6 per adult [](https://expedia.com/things-to-do/lucca-audio-guided-tour-of-the-historic-center.a51101571.activity-details) ![7 days Self Guided AI Audio Tours to Pisa and all Italy ](https://mediaim.expedia.com/localexpert/51260563/61e53eca-b41c-41b4-b7df-9ca6f583137d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 7 days Self Guided AI Audio Tours to Pisa and all Italy $12 per adult [](https://expedia.com/things-to-do/7-days-self-guided-ai-audio-tours-to-pisa-and-all-italy.a51260563.activity-details) ![Pisa: Baptistery and Cathedral Ticket with Audio Guide](https://mediaim.expedia.com/localexpert/44821591/cd562b5f-25fa-4a31-99e1-a5b910e472e8.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pisa: Baptistery and Cathedral Ticket with Audio Guide $24 per adult [](https://expedia.com/things-to-do/pisa-baptistery-and-cathedral-ticket-with-audio-guide.a44821591.activity-details) [See all activities in Sant'Antonio](https://expedia.com/things-to-do/search?rid=6270759) ## Sant'Antonio Hotel Deals ![Hotel Bologna](https://images.trvl-media.com/lodging/1000000/920000/914300/914236/18da2910_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Bologna Via Mazzini 57 Pisa PI Fully refundableReserve now, pay when you stay $124 nightly $144 total Mar 14 - Mar 15 Total with taxes and fees 8.8/10 Excellent! (1,009 reviews) I booked one double room but the hotel upgraded me to two singles. Other things I liked were good breakfast, especially the croissant was excellent, shuttle bus service to the airport at reasonable price. Everything was above average and the hotel well worth a 4-star rating. Reviewed on Feb 22, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F14%2F2026&endDate=3%2F15%2F2026&selected=914236&PinnedHotelID=914236&HadPinnedHotel=true®ionId=6270759) ![Prato dei Miracoli Residenza d'Epoca](https://images.trvl-media.com/lodging/108000000/107700000/107697000/107696957/0ec29b8d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Prato dei Miracoli Residenza d'Epoca Piazza del Duomo 5 Pisa PI Fully refundable $115 nightly $132 total Mar 4 - Mar 5 Total with taxes and fees 9.8/10 Exceptional! (290 reviews) Prato dei Miracoli Residenza d'Epoca Was exceptional! View was stunning, room was very clean and the staff was so welcoming. Would highly recommend Reviewed on Mar 2, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&selected=107696957&PinnedHotelID=107696957&HadPinnedHotel=true®ionId=6270759) ![Grand Hotel Duomo](https://images.trvl-media.com/lodging/1000000/20000/11600/11537/8fca9580_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Grand Hotel Duomo Via Santa Maria 94 Pisa PI Fully refundableReserve now, pay when you stay $114 nightly $133 total Mar 18 - Mar 19 Total with taxes and fees 8.6/10 Excellent! (1,141 reviews) Great location! Amazing breakfast! Reviewed on Mar 1, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&selected=11537&PinnedHotelID=11537&HadPinnedHotel=true®ionId=6270759) [See all 6,055 properties in Sant'Antonio](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026®ionId=6270759) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Sant'Antonio Vacation Packages ## SantAntonio Essential Information | Language | Italian | | --------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Euros | | Local Welcome | Ciao | | Local Goodbye | Ciao | | Closest Airport | Galileo Galilei Airport (PSA) | | Max Temp Winter | 50ºF | | Max Temp Summer | 80ºF | | Top Sights | [Cathedral of Pisa](https://www.expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction), [Calambrone Beach](https://www.expedia.com/Calambrone-Beach-Italy.d682860055616192512.Vacation-Attraction) and [Palazzo Blu](https://www.expedia.com/Palazzo-Blu-Pisa-City-Centre.d6159028.Vacation-Attraction) | ## More 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Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to travel to Sant'Antonio. > 2. Figure out your budget: Ensure you have enough money to cover everything from dining out and transportation to activities and flights. Your hotel will probably be the biggest expense during your trip to Sant'Antonio. > 3. Use our [trip planning tool](https://www.expedia.com/why/trip-planning) to explore Sant'Antonio: Research every part of your trip to Sant'Antonio with this comprehensive planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings. > 4. Work out your trip length: Consider how much time you want to spend exploring Sant'Antonio. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing. > 5. Combine your airfare and accommodations: After you've nailed down your travel dates and duration, book the ideal Sant'Antonio vacation package for you. > 6. Book any excursions or activities: Here's the fun part — locking in everything you want to do and see. Explore some of the best [things to do in Sant'Antonio](https://www.expedia.com/Things-To-Do-In-SantAntonio.d6270759.Travel-Guide-Activities) and reserve your tickets early to save time (and maybe some money too!). ### Does Expedia offer Book Now, Pay Later Sant'Antonio vacation packages? \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app