Sant'Antonio Vacations from $1,040

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Your SantAntonio Vacation

Reserve a SantAntonio vacation package and prepare to experience all this lively city has to offer. Consider staying in the neighborhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to Cathedral of Pisa, Knights Square and Pisa Baptistry, some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio vacation on Expedia.

The Latest Sant'Antonio vacation packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze

Aurum Firenze

Historic Centre of Florence
$1,040
per person
Oct 26 - Nov 1
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
The room was clean, staff reasonably friendly, breakfast breads were stale, air conditioning worked well. Conveniently located for train station

Reviewed on Sep 2, 2026

L'Andana

L'Andana

Save 100% on your flight
$2,178
per person
Oct 6 - Oct 12
found 1 hour ago
Roundtrip non-stop flight included
Miami (MIA) to Florence (FLR)
9.6/10 Exceptional! (94 reviews)
Villa Cora

Villa Cora

Oltrarno
Save 100% on your flight
$5,499
per person
Oct 8 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.8/10 Exceptional! (482 reviews)
Hotel La Scaletta Al Ponte Vecchio

Hotel La Scaletta Al Ponte Vecchio

Historic Centre of Florence
$2,179
per person
Oct 8 - Oct 12
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9/10 Wonderful! (1,010 reviews)
We had a great stay. The staff was super helpful in answering questions and providing recommendations. The rooms were very nicely sized and had great bathrooms. Perfectly located!!

Reviewed on Sep 2, 2026

Precise Tale Poggio Alla Sala

Precise Tale Poggio Alla Sala

Save 100% on your flight
$2,434
per person
Oct 6 - Oct 12
found 3 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Florence (FLR)
9.6/10 Exceptional! (162 reviews)
Fantastic stay!

Reviewed on Aug 30, 2026

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Stay near popular Sant'Antonio attractions

A river with buildings along its banks, a prominent church with a spire, and a mountain in the background.

Church of Santa Maria della Spina

9.4/10 (6 reviews)
In a city of remarkable architecture, this Gothic church on the River Arno is considered to be one of Pisa’s most impressive structures despite its small size.
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A street with a church and a blue building with a Andy Warhol exhibit.

Palazzo Blu

8.8/10 (26 reviews)
Explore this time capsule of classic Pisan life and learn about the achievements of this fascinating town’s most creative sons and daughters.
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A historic building with arched walkways, palm trees, and a flag on top.

Giardino Scotto

9.4/10 (3 reviews)
Explore the great outdoors at Giardino Scotto, a lovely green space in Sant'Antonio. Stroll along the riverfront in this culturally rich area, or check out its lively bars.
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Piazza Vittorio Emanuele II

You can learn about the history of Sant'Antonio with a stop at Piazza Vittorio Emanuele II. Stroll along the riverfront in this culturally rich area, or check out its lively bars.
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Saint Cristina Church

Saint Cristina Church is just one of the places to see in Sant'Antonio, so why not enjoy the other things to explore during your travels? Check out the stunning cathedral and lively bars in this culturally rich area.
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Santo Sepolcro

Learn about the local history of Sant'Antonio with a stop at Santo Sepolcro. Check out the stunning cathedral and lively bars in this culturally rich area.
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Arsenale Cinema

Enjoy a show at Arsenale Cinema, a storied theater in Sant'Antonio. Stroll along the riverfront in this culturally rich area, or check out its lively bars.
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Tuttomondo

Learn about the local history of Sant'Antonio when you take a trip to Tuttomondo. Amble around this culturally rich area's riverfront and enjoy its lively bars.
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What to do in Sant'Antonio

From La Spezia: Shore Excursion to Pisa

From La Spezia: Shore Excursion to Pisa

$45
per adult
94% of travellers recommend
From La Spezia: Shore Excursion to Pisa
From Livorno: Bus Transfer to the Leaning Tower of Pisa

From Livorno: Bus Transfer to the Leaning Tower of Pisa

$24
per adult
84% of travellers recommend
From Livorno: Bus Transfer to the Leaning Tower of Pisa
Villa Reale di Marlia Entrance Ticket

Villa Reale di Marlia Entrance Ticket

$21
per adult
100% of travellers recommend
Villa Reale di Marlia Entrance Ticket
See all activities in Sant'Antonio

Sant'Antonio Hotel Deals

Hotel Bologna

Hotel Bologna

Via Mazzini 57 Pisa PI
$137 nightly
$158 total
Sep 21 - Sep 22
Total with taxes and fees
8.8/10 Excellent! (1,008 reviews)
"The room was nice, but we were right on the road so quite a bit of traffic noise. A/C was fantastic. Breakfast was outstanding. The staff was very helpful."

Reviewed on Sep 3, 2026

Hotel Bologna
Max Hotel Livorno

Max Hotel Livorno

Via Giotto Ciardi, 28 Livorno LI
Fully refundableReserve now, pay when you stay
$79 nightly
$96 total
Oct 4 - Oct 5
Total with taxes and fees
8.6/10 Excellent! (1,001 reviews)
"Rooms were good. All television channels are in Italian if you are someone who doesn’t speak the language and wants to watch TV. There’s a nice big window that opens up so you can get fresh air however there’s no outdoor space so we personally felt trapped inside the hotel room, especially considering ..."

Reviewed on Aug 7, 2026

Max Hotel Livorno
Grand Hotel Duomo

Grand Hotel Duomo

Via Santa Maria 94 Pisa PI
Fully refundableReserve now, pay when you stay
$159 nightly
$182 total
Sep 16 - Sep 17
Total with taxes and fees
8.6/10 Excellent! (1,059 reviews)
"Lovely stay! The breakfast was really nice, the room was basic but clean and had a huge bed which was a treat. The shower was warm, but the water pressure was pretty rubbish. Worth bearing in mind if you have long hair you are hoping to wash! Otherwise, the staff were excellent and being able to ..."

Reviewed on Sep 1, 2026

Grand Hotel Duomo
See all 6,440 properties in Sant'Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Sant'Antonio Vacation Packages

SantAntonio Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Galileo Galilei Airport (PSA)
Max Temp Winter
50ºF
Max Temp Summer
80ºF
Top Sights
Cathedral of Pisa, Calambrone Beach and Palazzo Blu

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Frequently asked questions

How much does a Sant'Antonio vacation package cost?
Offering great value package deals from $1,040 on Expedia, you'll be pleasantly surprised at how much a vacation to Sant'Antonio costs! Expedia's packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Sant'Antonio?
October, November and December are the best times to look for cheap Sant'Antonio vacation packages. Choosing to travel in quieter months means you can typically find better prices on hotels and flights.
How many days is enough for Sant'Antonio?
Usually, a handful of days is enough to check out the major attractions during your Sant'Antonio vacation. But if you prefer to have some time to relax or take day trips, think about extending your itinerary.
Is it worth booking a vacation package to Sant'Antonio?
From leading attractions such as Arsenale Cinema and San Martino Church to its terrific culture, a Sant'Antonio vacation delivers big on experiences. With so much to do and see, it's time to find out for yourself why Sant'Antonio is such a good vacation destination.
How to find the best Sant'Antonio package deals?
Finding a cheap Sant'Antonio package deal is a breeze with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your maximum budget, add a few filters and see what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most affordable Sant'Antonio package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Sant'Antonio vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging flights and hotels separately. Better still, you can tailor your Sant'Antonio escape to fit your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sant'Antonio?
Score fantastic discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, grab one of our last-minute deals for an impromptu Sant'Antonio break.
How to plan a trip to Sant'Antonio?
  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to travel to Sant'Antonio.
  2. Figure out your budget: Ensure you have enough money to cover everything from dining out and transportation to activities and flights. Your hotel will probably be the biggest expense during your trip to Sant'Antonio.
  3. Use our trip planning tool to explore Sant'Antonio: Research every part of your trip to Sant'Antonio with this comprehensive planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Work out your trip length: Consider how much time you want to spend exploring Sant'Antonio. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing.
  5. Combine your airfare and accommodations: After you've nailed down your travel dates and duration, book the ideal Sant'Antonio vacation package for you.
  6. Book any excursions or activities: Here's the fun part — locking in everything you want to do and see. Explore some of the best things to do in Sant'Antonio and reserve your tickets early to save time (and maybe some money too!).
Does Expedia offer Book Now, Pay Later Sant'Antonio vacation packages?
Your Sant'Antonio trip is meant to be a relaxing escape from your busy life, not a source of money-related stress. So to give you more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.