Title: Sant'Antonio Vacation Packages 2026 from $1,620 | Expedia.com [Sant'Antonio Travel Guide](https://expedia.com/SantAntonio.dx6270759)[Hotels in Sant'Antonio](https://expedia.com/SantAntonio-Hotels.d6270759.Travel-Guide-Hotels)[Vacation Rentals in Sant'Antonio](https://expedia.com/SantAntonio-Vacation-Rentals.d6270759.Travel-Guide-VacationRentals)[Flights to Sant'Antonio](https://expedia.com/Cheap-Flights-To-SantAntonio.d6270759.Travel-Guide-Flights)[Car Rentals in Sant'Antonio](https://expedia.com/Car-Rentals-In-SantAntonio.d6270759.Car-Rental-Guide) ![](https://images.trvl-media.com/place/553248633938945235/f321690c-ea81-439e-8d85-51c90de9ab7f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Sant'Antonio Vacations from $1,620 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your SantAntonio Vacation Reserve a SantAntonio vacation package and prepare to experience all this lively city has to offer. Consider staying in the neighborhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to [Cathedral of Pisa](https://www.expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction), [Knights Square](https://www.expedia.com/Knights-Square-Pisa-City-Centre.d6073862.Vacation-Attraction) and [Pisa Baptistry](https://www.expedia.com/Pisa-Baptistry-Pisa-City-Centre.d6073896.Vacation-Attraction), some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio vacation on Expedia. ## The Latest Sant'Antonio vacation packages Price found within the past 48 hours. Click for updated prices. ![Residenza Florentia](https://images.trvl-media.com/lodging/2000000/1140000/1133600/1133528/da5e2175_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Residenza Florentia Historic Centre of Florence Save 100% on your flight $1,620 per person May 11 - May 17 found 7 hours ago Roundtrip non-stop flight included Boston (BOS) to Florence (FLR) 8.6/10 Excellent! (47 reviews) Location, accommodations, and communication. Simple but comfortable. A basic facilities, and nice AC, elevator, and luggage storage. Reviewed on Jun 12, 2025 ![Hotel Alessandra](https://images.trvl-media.com/lodging/2000000/1790000/1780300/1780229/4549f56f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Alessandra Historic Centre of Florence $4,817 per person Jun 9 - Jun 15 found 1 day ago Roundtrip flight included Orlando (MCO) to Florence (FLR) 9.2/10 Wonderful! (853 reviews) Staying here was a wonderful experience! Hotel Alessandra was within walking distance of everything we wanted to see in Florence, including one street away from the Ponte Vecchio. The room was always very clean and the staff was extremely welcoming and kind. We loved our stay here and would absolutely stay here on our next trip to Florence! Reviewed on Mar 30, 2026 ![Hotel Berchielli](https://images.trvl-media.com/lodging/1000000/530000/521300/521260/3061994d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Berchielli Historic Centre of Florence $5,448 per person Jun 9 - Jun 15 found 1 day ago Roundtrip flight included Orlando (MCO) to Florence (FLR) 9.4/10 Exceptional! (1,001 reviews) Very good Breakfast with many food options. Great service ! Reviewed on Jan 21, 2026 ![Hotel De La Ville](https://images.trvl-media.com/lodging/1000000/30000/21500/21408/05410bf8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel De La Ville Historic Centre of Florence $5,411 per person Jun 2 - Jun 8 found 1 day ago Roundtrip flight included Orlando (MCO) to Florence (FLR) 9.2/10 Wonderful! (1,003 reviews) This was my second stay and my go to in Florence. Lovely hotel and staff and great location. Breakfast is expensive but everything in the core is. Only wish there was a plug by the bed for phone charging. They brought me an extension cord. Will stay again! Grazie. Reviewed on Apr 1, 2026 ![The FRAME Hotel](https://images.trvl-media.com/lodging/31000000/30310000/30304300/30304275/95ada636_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The FRAME Hotel Historic Centre of Florence $5,593 per person Jun 2 - Jun 8 found 1 day ago Roundtrip flight included Orlando (MCO) to Florence (FLR) 9.6/10 Exceptional! (623 reviews) Staff was so nice! Room was clean and well maintained. Location is great would definitely come back Reviewed on Mar 18, 2026 Don't see what you're looking for? See all available trips from Columbus to Sant'Antonio [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-01/2026-05-08/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PSA&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ### Discover the most popular places to visit in Sant'Antonio ![Leaning Tower](https://images.trvl-media.com/place/6270669/ad1bc6f8-1f44-482a-8858-2e921455b806.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Leaning Tower 5/5(219 reviews) The jewel in Pisa’s crown is this iconic cylindrical bell tower, which has become world-famous because of its bizarre angle. [](https://expedia.com/Leaning-Tower-Pisa-City-Centre.d6270669.Vacation-Attraction) ![Piazza dei Miracoli](https://images.trvl-media.com/place/6073918/658143fb-f5f7-45a8-a980-1b03332e82c0.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza dei Miracoli 4.5/5(86 reviews) The Leaning Tower of Pisa makes this walled square the most photographed square in Pisa, but its other grand structures are also worth capturing. [](https://expedia.com/Piazza-Dei-Miracoli-Pisa-City-Centre.d6073918.Vacation-Attraction) ![Cathedral of Pisa](https://images.trvl-media.com/place/6073838/666c72a9-553f-45c9-adc8-7845c163cdab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cathedral of Pisa 4.5/5(196 reviews) At the heart of Piazza dei Miracoli lies an impressive example of Romanesque architecture, one of the most sacred sites in Italy. [](https://expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction) ### What to do in Sant'Antonio ![Pisa and Piazza dei Miracoli Half Day Tour from Florence](https://mediaim.expedia.com/localexpert/558114/ee5005a3-7dc7-4d52-b37b-cb457ae399b1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Pisa and Piazza dei Miracoli Half Day Tour from Florence $32 per adult **84%** of travellers recommend [](https://expedia.com/things-to-do/pisa-and-piazza-dei-miracoli-half-day-tour-from-florence.a558114.activity-details) ![Lucca : audio-guided tour of the historic center](https://mediaim.expedia.com/localexpert/51101571/5d3ed7e6-2c4e-4afc-be77-e7d1cf7ffdfc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Lucca : audio-guided tour of the historic center $6 per adult [](https://expedia.com/things-to-do/lucca-audio-guided-tour-of-the-historic-center.a51101571.activity-details) ![7 days Self Guided AI Audio Tours to Pisa and all Italy ](https://mediaim.expedia.com/localexpert/51260563/61e53eca-b41c-41b4-b7df-9ca6f583137d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 7 days Self Guided AI Audio Tours to Pisa and all Italy $12 per adult [](https://expedia.com/things-to-do/7-days-self-guided-ai-audio-tours-to-pisa-and-all-italy.a51260563.activity-details) [See all activities in Sant'Antonio](https://expedia.com/things-to-do/search?rid=6270759) ## Sant'Antonio Hotel Deals ![Hotel Bologna](https://images.trvl-media.com/lodging/1000000/920000/914300/914236/18da2910_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Bologna Via Mazzini 57 Pisa PI $120 nightly $139 total Apr 29 - Apr 30 Total with taxes and fees 8.8/10 Excellent! (1,003 reviews) Fantastic location, very walkable to the shopping area and leaning tower, near decent pizza place and lovely cafe. Quiet road. Superb breakfast! Lovely staff, really helpful and friendly. We had a great stay. Reviewed on Mar 23, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F29%2F2026&endDate=4%2F30%2F2026&selected=914236&PinnedHotelID=914236&HadPinnedHotel=true®ionId=6270759) ![Prato dei Miracoli Residenza d'Epoca](https://images.trvl-media.com/lodging/108000000/107700000/107697000/107696957/0ec29b8d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Prato dei Miracoli Residenza d'Epoca Piazza del Duomo 5 Pisa PI Fully refundable $189 nightly $214 total Apr 14 - Apr 15 Total with taxes and fees 9.8/10 Exceptional! (308 reviews) Great location in Pisa helpful staff and very comfortable bed Reviewed on Mar 30, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F14%2F2026&endDate=4%2F15%2F2026&selected=107696957&PinnedHotelID=107696957&HadPinnedHotel=true®ionId=6270759) ![Sina Astor](https://images.trvl-media.com/lodging/1000000/580000/573700/573657/693d7ffb_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sina Astor Viale Giosue' Carducci, 54 Viareggio LU Fully refundableReserve now, pay when you stay $130 nightly $148 total Apr 12 - Apr 13 Total with taxes and fees 8.6/10 Excellent! (477 reviews) I did not have breakfast. Reviewed on Apr 1, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=573657&PinnedHotelID=573657&HadPinnedHotel=true®ionId=6270759) [See all 6,182 properties in Sant'Antonio](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=6270759) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Sant'Antonio Vacation Packages ## SantAntonio Essential Information | Language | Italian | | --------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | Euros | | Local Welcome | Ciao | | Local Goodbye | Ciao | | Closest Airport | Galileo Galilei Airport (PSA) | | Max Temp Winter | 50ºF | | Max Temp Summer | 80ºF | | Top Sights | [Cathedral of Pisa](https://www.expedia.com/Cathedral-Of-Pisa-Pisa-City-Centre.d6073838.Vacation-Attraction), [Calambrone Beach](https://www.expedia.com/Calambrone-Beach-Italy.d682860055616192512.Vacation-Attraction) and [Palazzo Blu](https://www.expedia.com/Palazzo-Blu-Pisa-City-Centre.d6159028.Vacation-Attraction) | ## More 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Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to travel to Sant'Antonio. > 2. Figure out your budget: Ensure you have enough money to cover everything from dining out and transportation to activities and flights. Your hotel will probably be the biggest expense during your trip to Sant'Antonio. > 3. Use our [trip planning tool](https://www.expedia.com/why/trip-planning) to explore Sant'Antonio: Research every part of your trip to Sant'Antonio with this comprehensive planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings. > 4. Work out your trip length: Consider how much time you want to spend exploring Sant'Antonio. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing. > 5. Combine your airfare and accommodations: After you've nailed down your travel dates and duration, book the ideal Sant'Antonio vacation package for you. > 6. Book any excursions or activities: Here's the fun part — locking in everything you want to do and see. Explore some of the best [things to do in Sant'Antonio](https://www.expedia.com/Things-To-Do-In-SantAntonio.d6270759.Travel-Guide-Activities) and reserve your tickets early to save time (and maybe some money too!). ### Does Expedia offer Book Now, Pay Later Sant'Antonio vacation packages? \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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