Sant'Antonio Vacations from $1,378

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Your SantAntonio Vacation

Reserve a SantAntonio vacation package and prepare to experience all this lively city has to offer. Consider staying in the neighborhood of Vecchiano, which is great for bars and pubs, walking and nature. Fill your spare time with visits to Cathedral of Pisa, Knights Square and Pisa Baptistry, some of the things you should see during your trip to SantAntonio. A couple of clicks is all it takes to put together the perfect SantAntonio vacation on Expedia.

The Latest Sant'Antonio vacation packages

Price found within the past 48 hours. Click for updated prices.
Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Price was $2,090, price is now $1,378 per person
$1,378
per person
Jun 3 - Jun 9
found 22 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
Super clean room, modern, good shower and bed, nice and quiet, 10 minutes from the train station, breakfast was done in time slots and was ok maybe could have had more selection, staff were friendly, my only bugbear was the WiFi was really slow and i ended up using my hot-spot instead

Reviewed on Apr 12, 2026

Aurum Uffizi

Aurum Uffizi

4 out of 5
Historic Centre of Florence
Save 100% on your flight
Price was $2,644, price is now $1,587 per person
$1,587
per person
May 22 - May 27
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,000 reviews)
The room was clean and newly renovated. Having breakfast included was great for a quick bite so I could focus on exploring instead of searching and waiting in line. Would definitely recommend a stay here

Reviewed on Apr 9, 2026

Precise Tale Poggio Alla Sala

Precise Tale Poggio Alla Sala

5 out of 5
Save 100% on your flight
Price was $4,770, price is now $3,027 per person
$3,027
per person
May 24 - May 29
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.4/10 Exceptional! (124 reviews)
Most gorgeous setting, lovely staff and delicious food. We will definitely be back!

Reviewed on Apr 5, 2026

LHP Hotel River & SPA

LHP Hotel River & SPA

5 out of 5
Historic Centre of Florence
Price was $2,355, price is now $1,722 per person
$1,722
per person
May 24 - May 29
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
8.8/10 Excellent! (253 reviews)
The rooms were clean and the staff was very friendly. Breakfast had a great variety of food to choose from and the staff was wonderful!

Reviewed on Nov 29, 2025

Eurostars Florence Boutique

Eurostars Florence Boutique

4 out of 5
Historic Centre of Florence
Price was $2,228, price is now $1,636 per person
$1,636
per person
May 22 - May 27
found 13 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.6/10 Excellent! (483 reviews)
The room was clean and the staff very accommodating. The breakfast was quite sufficient and had a good variety. The location is great. It's a short walk from the square, shopping and from restaurants.

Reviewed on Dec 13, 2025

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Discover the most popular places to visit in Sant'Antonio

Leaning Tower

Leaning Tower

5/5(219 reviews)

The jewel in Pisa’s crown is this iconic cylindrical bell tower, which has become world-famous because of its bizarre angle.

Leaning Tower
Piazza dei Miracoli

Piazza dei Miracoli

4.5/5(86 reviews)

The Leaning Tower of Pisa makes this walled square the most photographed square in Pisa, but its other grand structures are also worth capturing.

Piazza dei Miracoli
Cathedral of Pisa

Cathedral of Pisa

4.5/5(196 reviews)

At the heart of Piazza dei Miracoli lies an impressive example of Romanesque architecture, one of the most sacred sites in Italy.

Cathedral of Pisa

What to do in Sant'Antonio

Pisa and Piazza dei Miracoli Half Day Tour from Florence

Pisa and Piazza dei Miracoli Half Day Tour from Florence

$32
per adult
84% of travellers recommend
Pisa and Piazza dei Miracoli Half Day Tour from Florence
Puccini - meeting point

visita guidata a Lucca: ITALIANO or ENGLISH (2 guides)

$17
per adult
100% of travellers recommend
visita guidata a Lucca: ITALIANO or ENGLISH (2 guides)
From Livorno: Shore Excursion to Florence and Pisa

From Livorno: Shore Excursion to Florence and Pisa

$90
per adult
86% of travellers recommend
From Livorno: Shore Excursion to Florence and Pisa
See all activities in Sant'Antonio

Sant'Antonio Hotel Deals

Hotel Bologna

Hotel Bologna

4 out of 5
Via Mazzini 57 Pisa PI
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $145 total per night from Apr 29 to Apr 30
$145 total
Apr 29 - Apr 30
Total with taxes and fees
8.8/10 Excellent! (1,003 reviews)
The breakfast area was almost full and some dishes were not replaced. There was fresh pineapple and and kiwi but tinned pear and peaches. Automated machine to make fresh pancakes with honey Nutella and maple syrup. Cakes and croissants which were almost over by 9.30 am.

Reviewed on Apr 11, 2026

Hotel Bologna
Prato dei Miracoli Residenza d'Epoca

Prato dei Miracoli Residenza d'Epoca

Piazza del Duomo 5 Pisa PI
$210 nightly
The price is $237 total per night from Apr 15 to Apr 16
$237 total
Apr 15 - Apr 16
Total with taxes and fees
9.8/10 Exceptional! (314 reviews)
Location was great, allowed walking to all parts of town. The staff was amazing with check-in and any questions, plus, helped with our Italian language skills. Great experience overall. Highly recommend staying here.

Reviewed on Apr 9, 2026

Prato dei Miracoli Residenza d'Epoca
Grand Hotel Duomo

Grand Hotel Duomo

4 out of 5
Via Santa Maria 94 Pisa PI
$161 nightly
The price is $184 total per night from Apr 14 to Apr 15
$184 total
Apr 14 - Apr 15
Total with taxes and fees
8.6/10 Excellent! (1,118 reviews)
nice clean hotel friendly staff good breakfast great position next to the tower

Reviewed on Apr 12, 2026

Grand Hotel Duomo
See all 6,152 properties in Sant'Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Sant'Antonio Vacation Packages

SantAntonio Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Galileo Galilei Airport (PSA)
Max Temp Winter
50ºF
Max Temp Summer
80ºF
Top Sights
Cathedral of Pisa, Calambrone Beach and Palazzo Blu

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Frequently asked questions

How much does a Sant'Antonio vacation package cost?
Offering great value package deals from $1,378 on Expedia, you'll be pleasantly surprised at how much a vacation to Sant'Antonio costs! Expedia's packages mean less travel planning for you and greater savings.
What are the cheapest months to go to Sant'Antonio?
October, November and December are the best times to look for cheap Sant'Antonio vacation packages. Choosing to travel in quieter months means you can typically find better prices on hotels and flights.
How many days is enough for Sant'Antonio?
Usually, a handful of days is enough to check out the major attractions during your Sant'Antonio vacation. But if you prefer to have some time to relax or take day trips, think about extending your itinerary.
Is it worth booking a vacation package to Sant'Antonio?
From leading attractions such as Arsenale Cinema and San Martino Church to its terrific culture, a Sant'Antonio vacation delivers big on experiences. With so much to do and see, it's time to find out for yourself why Sant'Antonio is such a good vacation destination.
How to find the best Sant'Antonio package deals?
Finding a cheap Sant'Antonio package deal is a breeze with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your maximum budget, add a few filters and see what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Sort the results by "Price: low to high" to discover the most affordable Sant'Antonio package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.
Is it cheaper to book a Sant'Antonio vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging flights and hotels separately. Better still, you can tailor your Sant'Antonio escape to fit your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Sant'Antonio?
Score fantastic discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, grab one of our last-minute deals for an impromptu Sant'Antonio break.
How to plan a trip to Sant'Antonio?

  1. Pick the perfect time to travel: Your schedule, preferred season and the type of weather you like can all influence your decision on when to travel to Sant'Antonio.
  2. Figure out your budget: Ensure you have enough money to cover everything from dining out and transportation to activities and flights. Your hotel will probably be the biggest expense during your trip to Sant'Antonio.
  3. Use our trip planning tool to explore Sant'Antonio: Research every part of your trip to Sant'Antonio with this comprehensive planner. Invite family or friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Work out your trip length: Consider how much time you want to spend exploring Sant'Antonio. Plan your itinerary so you can get to all the attractions and activities you're interested in without rushing.
  5. Combine your airfare and accommodations: After you've nailed down your travel dates and duration, book the ideal Sant'Antonio vacation package for you.
  6. Book any excursions or activities: Here's the fun part — locking in everything you want to do and see. Explore some of the best things to do in Sant'Antonio and reserve your tickets early to save time (and maybe some money too!).

Does Expedia offer Book Now, Pay Later Sant'Antonio vacation packages?
Your Sant'Antonio trip is meant to be a relaxing escape from your busy life, not a source of money-related stress. So to give you more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there are no late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.