Sant'Antonio Vacations from $1,081

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

The Latest Sant'Antonio vacation packages

Price found within the past 48 hours. Click for updated prices.
Park Hotel Argento

Park Hotel Argento

4 out of 5
Price was $1,197, price is now $1,081 per person
$1,081
per person
Oct 16 - Oct 19
found 9 hours ago
Roundtrip non-stop flight included
New York (JFK) to Pisa (PSA)
9.6/10 Exceptional! (409 reviews)
Beautiful hotel with friendly staff .. the courtesy bus was an excellent addition and breakfast was lovely x

Reviewed on Sep 5, 2025

Hotel Piccolo Portofino

Hotel Piccolo Portofino

4 out of 5
Price was $2,223, price is now $1,991 per person
$1,991
per person
Nov 1 - Nov 4
found 1 day ago
Roundtrip flight included
San Antonio (SAT) to Pisa (PSA)
9/10 Wonderful! (573 reviews)
The hotel is very convenient with a beautiful view of Portofino. Hotel needs an update, pricey for an old looking hotel.

Reviewed on Aug 16, 2025

Hotel Blu di Te

Hotel Blu di Te

4 out of 5
Price was $1,985, price is now $1,790 per person
$1,790
per person
Nov 1 - Nov 4
found 1 day ago
Roundtrip flight included
San Antonio (SAT) to Pisa (PSA)
9.6/10 Exceptional! (214 reviews)
Lovely property and a lovely staff who went above and beyond to make our stay memorable, especially for my 2 year old son.

Reviewed on Sep 5, 2025

SPLENDIDE RIVIERA

SPLENDIDE RIVIERA

4 out of 5
Price was $1,817, price is now $1,673 per person
$1,673
per person
Nov 1 - Nov 4
found 1 day ago
Roundtrip flight included
San Antonio (SAT) to Pisa (PSA)
No reviews
Grand Hotel Portovenere

Grand Hotel Portovenere

5 out of 5
Price was $2,763, price is now $2,550 per person
$2,550
per person
Oct 23 - Oct 26
found 12 hours ago
Roundtrip non-stop flight included
Minneapolis (MSP) to Pisa (PSA)
9.4/10 Exceptional! (451 reviews)
The location was perfect as far as getting the ferry to the Cinque Terra ports

Reviewed on Aug 9, 2025

Don't see what you're looking for?
See all available trips from Columbus to Sant'Antonio
View all trips

Sant'Antonio Hotel Deals

Terme di Saturnia Natural Spa & Golf Resort - The Leading Hotels of the World

Terme di Saturnia Natural Spa & Golf Resort - The Leading Hotels of the World

5 out of 5
Via della Follonata, SP Saturnia, Manciano, GR
Fully refundableReserve now, pay when you stay
$497 nightly
The price is $547 total per night from Sep 23 to Sep 24
$547 total
Sep 23 - Sep 24
Total with taxes and fees
Terme di Saturnia Natural Spa & Golf Resort - The Leading Hotels of the World
Castello di Velona Resort Thermal SPA & Winery

Castello di Velona Resort Thermal SPA & Winery

5 out of 5
Località Velona, Castelnuovo dell'Abate, Montalcino, SI
Fully refundableReserve now, pay when you stay
$755 nightly
The price is $842 total per night from Oct 7 to Oct 8
$842 total
Oct 7 - Oct 8
Total with taxes and fees
Castello di Velona Resort Thermal SPA & Winery
Rosewood Castiglion del Bosco

Rosewood Castiglion del Bosco

5 out of 5
Localita Castiglion del Bosco, Montalcino, SI
$2,202 nightly
The price is $2,434 total per night from Oct 10 to Oct 11
$2,434 total
Oct 10 - Oct 11
Total with taxes and fees
Rosewood Castiglion del Bosco
See all 1,709 properties in Sant'Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Sant'Antonio vacation package cost?
Offering excellent value package deals from $1,081 on Expedia, you'll be pleasantly surprised at how much a vacation to Sant'Antonio costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Sant'Antonio?
You can typically find lower rates and greater availability in October, November and December. Explore our cheap Sant'Antonio vacation packages and you could get some excellent off-season deals.
How many days is enough for Sant'Antonio?
With a well-planned itinerary, you can easily visit the most popular Sant'Antonio attractions in a handful of days. But if you want to discover lesser-known spots or take day trips, consider booking your Sant'Antonio vacation for longer.
How to find the best Sant'Antonio package deals?
Begin your search for a Sant'Antonio package deal by entering your preferred trip dates and destination under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Sant'Antonio package deal right away, simply play around with your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Sant'Antonio getaway off to a flying start.
Is it cheaper to book a Sant'Antonio vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights individually. Better still, you can customize your Sant'Antonio trip to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Sant'Antonio?
If you've got your Sant'Antonio vacation dates locked in, book as early as you can to score some awesome deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for traveling on a whim.
Does Expedia offer Book Now, Pay Later Sant'Antonio vacation packages?
If you're like us, you love exploring new places but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the cost of your Sant'Antonio break over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.