Santa Croce Vacations from $1,175

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
B&B HOTEL Venezia Laguna
Hotel de l'Alboro
Hotel Olimpia Venice, BW Signature Collection
TORRE DELL'OROLOGIO SIGNATURE RESIDENCE
Hotel San Luca

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce

Santa Croce Hotel Deals

Hotel Antiche Figure

Hotel Antiche Figure

3 out of 5
Santa Croce 687 Venice VE
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $180 total per night from Dec 2 to Dec 3
$180 total
Dec 2 - Dec 3
Total with taxes and fees
9.8/10 Exceptional! (1,001 reviews)
"We spent 3 nights in a family room in the Annex, and the room was perfect for our family. The room was meticulously designed and cleaned, and we appreciated how quiet it was. We didn't have a problem with the stairs, as we had asked ahead of time if it's possible to be on a lower floor (and we were ..."

Reviewed on Nov 2, 2026

Hotel Antiche Figure
Santa Chiara Hotel

Santa Chiara Hotel

4.5 out of 5
Santa Croce 548 Venice VE
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $212 total per night from Nov 29 to Nov 30
$212 total
Nov 29 - Nov 30
Total with taxes and fees
9.2/10 Wonderful! (428 reviews)
"Absolutely wonderful place to stay! The location was perfect. The taxi could drive us from the airport straight to the doorstep. The water taxi stop was right outside the back door. The staff were very helpful from arranging dinner reservations to providing a private boat and tour of a wonderful ..."

Reviewed on Nov 2, 2026

Santa Chiara Hotel
Hotel Canal Grande

Hotel Canal Grande

4 out of 5
Santa Croce 932 Venice VE
Fully refundableReserve now, pay when you stay
$154 nightly
The price is $179 total per night from Nov 16 to Nov 17
$179 total
Nov 16 - Nov 17
Total with taxes and fees
9.6/10 Exceptional! (1,005 reviews)
"Loved this hotel. Right on the Grand Canal with its own dock for water taxis. Our room was very nice and the bed comfortable. The breakfast choices were plentiful. The staff (front desk and breakfast service) were exemplary!! Highly recommend."

Reviewed on Nov 2, 2026

Hotel Canal Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Croce attractions

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.