Title: Santa Croce Vacation Packages 2026 from $1,588 | Expedia.com

[Santa Croce Travel Guide](https://expedia.com/Venice-Santa-Croce.dx6046564)[Hotels in Santa Croce](https://expedia.com/Santa-Croce-Venice-Hotels.0-n6046564-0.Travel-Guide-Filter-Hotels)[Flights to Venice](https://expedia.com/Cheap-Flights-To-Venice.d179981.Travel-Guide-Flights)[Things to do in Venice](https://expedia.com/Things-To-Do-In-Venice.d179981.Travel-Guide-Activities)[Car Rentals in Santa Croce](https://expedia.com/Car-Rentals-In-Santa-Croce.d6046564.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6046564/aae7b138-5455-4af7-94dd-26683edbe0d8.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santa Croce Vacations from $1,588

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
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Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
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Rest easy  
Plan, book, and manage your trip all in one place

## Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including [Rialto Bridge](https://www.expedia.com/Rialto-Bridge-Venice-City-Center.d508806.Vacation-Attraction), [St. Marks Basilica](https://www.expedia.com/St-Marks-Basilica-Venice-City-Center.d503202.Vacation-Attraction) and [St. Marks Square](https://www.expedia.com/St-Marks-Square-San-Marco.d503200.Vacation-Attraction). Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

## The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![Hotel Ca Marinella](https://images.trvl-media.com/lodging/8000000/7260000/7251800/7251746/0117db7f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Ca Marinella

Castello

Save 100% on your flight

$1,588

per person

May 15 - May 19

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Venice (VCE)

8.6/10 Excellent! (322 reviews)

Good location, good staff, clean

Reviewed on Feb 13, 2026

![Hotel Bisanzio](https://images.trvl-media.com/lodging/1000000/10000/5500/5458/5495fe83_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Bisanzio

Castello

$2,625

per person

May 16 - May 22

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Venice (VCE)

9/10 Wonderful! (1,003 reviews)

There’s no air conditioning available or option as it’s centralized

Reviewed on Apr 4, 2026

![Hotel Ai Cavalieri di Venezia](https://images.trvl-media.com/lodging/10000000/9410000/9407600/9407521/d0e66112_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Ai Cavalieri di Venezia

Castello

Save 100% on your flight

$4,412

per person

May 16 - May 22

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Venice (VCE)

9.8/10 Exceptional! (1,001 reviews)

Everything was absolutely amazing. The staff were great and the location of the hotel was perfect for us. My only dislike was that I couldn't change the temperature of the room it was nice enough to open the windows but I attract misquitos and didnt want them in the room. Would definitely stay there again and would have liked to try the spa. They had the best breakfast out of all the places we went to.

Reviewed on Apr 1, 2026

![Eurostars Residenza Cannaregio Hotel](https://images.trvl-media.com/lodging/1000000/990000/982000/981929/fa4b0d39_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Eurostars Residenza Cannaregio Hotel

Cannaregio

$2,388

per person

May 24 - May 30

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Venice (VCE)

8.6/10 Excellent! (1,000 reviews)

Better than expected. Room for a family of 5 was great, split level gave us more space than we expected for being in Venice. Nice quiet part of the city too.

Reviewed on Apr 3, 2026

![Ca' Sagredo](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/1e825745_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Ca' Sagredo

Venice City Center

$3,320

per person

May 16 - May 22

found 1 day ago

Roundtrip non-stop flight included

Atlanta (ATL) to Venice (VCE)

9.2/10 Wonderful! (485 reviews)

Room was very clean and our terrace was wonderful. The staff was very friendly and accommodating.

Reviewed on Apr 5, 2026

## Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. [Learn more about Santa Croce](https://expedia.com/Venice-Santa-Croce.dx6046564)

![Venice City Center](https://images.trvl-media.com/place/6049646/e3c4afd6-1e37-4d4e-8f71-1bcc2b96f99a.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Venice City Center

4 out of top 10 points of interest in this area

 Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water. 

[Find hotel + flight trips in Venice City Center](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Venice%20City%20Center&DestID=6222433&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![San Marco](https://images.trvl-media.com/place/6005315/7aeaf7e3-bd50-45a9-8773-938edd990a22.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Marco

1 out of top 10 points of interest in this area

4.5/5(1,946 area reviews)

 In the heart of Venice, this densely built area boasts iconic attractions like St Mark's Square, Saint Mark's Basilica, and the Doge's Palace. Find numerous hotels, banks, and high-end shops amid the bustling tourist scene. 

[Find hotel + flight trips in San Marco](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Marco&DestID=6005315&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![San Polo](https://images.trvl-media.com/place/6005317/25bd17a5-5e0d-4cf6-a192-3237fd41e600.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Polo

4.5/5(304 area reviews)

 Smallest and most central sestiere, San Polo boasts churches in the west, palaces in the east, and iconic attractions like Rialto Bridge and Scuola Grande di San Rocco. 

[Find hotel + flight trips in San Polo](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Polo&DestID=6005317&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Cannaregio](https://images.trvl-media.com/place/506748/daf8052e-57f2-496e-8cde-07f79dc4d86c.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Cannaregio

4.5/5(1,013 area reviews)

 Explore historic churches like Santa Maria di Nazareth and Santa Maria dei Miracoli, or admire stunning palazzos such as Ca' d'Oro and Ca' Vendramin Calergi. Enjoy morning markets, local shops, and quaint cafés in this residential, peaceful district. 

[Find hotel + flight trips in Cannaregio](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Cannaregio&DestID=6005309&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Dorsoduro](https://images.trvl-media.com/place/6049646/4cff27d0-931f-4dbe-8459-aa94f48a7e6e.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Dorsoduro

4.5/5(428 area reviews)

 Boasting the highest land areas in Venice, this sestiere features the stunning Basilica of Santa Maria della Salute and the picturesque Zattere quay. Easily connect to San Marco via Ponte dell'Accademia. 

[Find hotel + flight trips in Dorsoduro](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Dorsoduro&DestID=6049646&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Santa Croce Hotel Deals

![Palazzo Marcello Hotel al Sole](https://images.trvl-media.com/lodging/1000000/530000/527200/527182/156c9c11_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Palazzo Marcello Hotel al Sole

Santa Croce 134/136 Venice VE

$214 nightly

$243 total

Apr 15 - Apr 16

Total with taxes and fees

8.6/10 Excellent! (845 reviews)

Good service and convenient location

Reviewed on Mar 22, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F15%2F2026&endDate=4%2F16%2F2026&selected=527182&PinnedHotelID=527182&HadPinnedHotel=true&regionId=6046564)

![Hotel Antiche Figure](https://images.trvl-media.com/lodging/1000000/980000/976900/976826/97b61f2e_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Antiche Figure

Santa Croce 687 Venice VE

$236 nightly

$268 total

Apr 28 - Apr 29

Total with taxes and fees

9.8/10 Exceptional! (1,003 reviews)

Very nice

Reviewed on Apr 5, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F28%2F2026&endDate=4%2F29%2F2026&selected=976826&PinnedHotelID=976826&HadPinnedHotel=true&regionId=6046564)

![Hotel Canal Grande](https://images.trvl-media.com/lodging/3000000/2930000/2921400/2921301/42cd722c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Canal Grande

Santa Croce 932 Venice VE

$227 nightly

$260 total

Apr 12 - Apr 13

Total with taxes and fees

9.6/10 Exceptional! (1,000 reviews)

All very good, staffers are very nice, only thing need to improve is to provid anti-skip mat for the bathtub/shower for guest safty. The tub is pretty slippery.

Reviewed on Apr 6, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=2921301&PinnedHotelID=2921301&HadPinnedHotel=true&regionId=6046564)

[See all 6,235 properties in Santa Croce](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F9%2F2026&endDate=4%2F10%2F2026&regionId=6046564)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Santa Croce

![moderne Fußgängerbrücke über den Canal Grande Venedig](https://images.trvl-media.com/place/508730/b2d959cf-6c5c-4a63-a47f-d70632f3e6f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Piazzale Roma

4.5/5(634 reviews)

You can learn about the local history of Venice during your trip to a top site like Piazzale Roma. Stroll along the marina or visit the stunning cathedral in the area. 

[](https://expedia.com/Piazzale-Roma-Santa-Croce.d508730.Vacation-Attraction)

![Fondaco dei Turchi am Canal Grande in Venedig, Italien](https://images.trvl-media.com/place/503193/457d876f-b87e-4e60-88e6-ec8899771442.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Fondaco dei Turchi

5/5(4 reviews)

You can browse the exhibits at Fondaco dei Turchi, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the churches in the area. 

[](https://expedia.com/Fondaco-Dei-Turchi-Venice-City-Center.d503193.Vacation-Attraction)

![Milan, Italy February 17th 2019 Fondazione Prada with reflective pool, photographed from Adriano Olivetti's square](https://images.trvl-media.com/place/553248621533001726/1befcd1d-23b5-478c-8d6c-1afb3679770a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Fondazione Prada

You can browse the exhibits at Fondazione Prada, a museum with a storied past, during your trip to Venice. Visit the area's churches or amble around its marina. 

[](https://expedia.com/Fondazione-Prada-Venice-City-Center.d553248621533001726.Vacation-Attraction)

### Things to do

![Venice in a Day with St. Mark's Basilica, Doge's Palace, & Gondola Ride](https://mediaim.expedia.com/localexpert/292011/9d791e58-560f-4dfc-bb58-9f0688dde114.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Venice in a Day:Gondola Ride, Doge's Palace, St Mark's Basilica & City Tour

$169

per adult

**94%** of travellers recommend

[](https://expedia.com/things-to-do/venice-in-a-daygondola-ride.a292011.activity-details)

![Tour of The Real Hidden Venice](https://mediaim.expedia.com/localexpert/3216086/129b7f54-c2d1-4956-9617-024a9d0818ec.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Tour of The Real Hidden Venice

$68

per adult

**92%** of travellers recommend

[](https://expedia.com/things-to-do/tour-of-the-real-hidden-venice.a3216086.activity-details)

![Venice: Basilica, Doge's Palace, Gondola Ride & History Gallery](https://mediaim.expedia.com/localexpert/48868052/30b94ed5-e7b2-49ed-8765-f7692fe5c90a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Venice: Basilica, Doge's Palace, Gondola Ride & History Gallery

$152

per adult

[](https://expedia.com/things-to-do/venice-basilica.a48868052.activity-details)

[See all activities in Venice](https://expedia.com/things-to-do/search?rid=6046564)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.