Santa Croce Vacations from $1,121

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Bisanzio
Baglioni Hotel Luna - The Leading Hotels of the World
Hotel Marconi
San Clemente Palace, Venice - Managed by Mandarin Oriental
Cà Bonfadini Historic Experience

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce

Santa Croce Hotel Deals

Hotel Arlecchino

Hotel Arlecchino

3 out of 5
Fondamenta Delle Burchielle, Santa Croce 390, Venice, VE
$154 nightly
The price is $178 total per night from Aug 24 to Aug 25
$178 total
Aug 24 - Aug 25
Total includes taxes and fees
9/10 Wonderful! (992 reviews)
"Lovely area, beautiful views and a nice clean hotel. It was rather loud outside, but not within their control. Overall a fantastic place to stay!"

Reviewed on Aug 15, 2025

Hotel Arlecchino
Hotel Carlton on the Grand Canal

Hotel Carlton on the Grand Canal

4 out of 5
Sestiere Di Santa Croce 578, Venice, VE
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $179 total per night from Aug 24 to Aug 25
$179 total
Aug 24 - Aug 25
Total includes taxes and fees
8.2/10 Very Good! (1,005 reviews)
"Great location close to the bus, train, and parking. Has its own restaurant and very good breakfast."

Reviewed on Aug 15, 2025

Hotel Carlton on the Grand Canal
Hotel Al Duca Di Venezia

Hotel Al Duca Di Venezia

3 out of 5
Fontego dei Turchi 1739 Santa Croce, Venice, VE
Fully refundableReserve now, pay when you stay
$157 nightly
The price is $181 total per night from Aug 20 to Aug 21
$181 total
Aug 20 - Aug 21
Total includes taxes and fees
9/10 Wonderful! (993 reviews)
"Perfect place to stay in Venice!!! Staff amazing! Bathroom shower needs to be cleaning better."

Reviewed on Aug 16, 2025

Hotel Al Duca Di Venezia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Croce

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.