Santa Croce Vacations from $1,036

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Ca' Alvise

Hotel Ca' Alvise

4 out of 5
Venice City Center
Save 100% on your flight
per person
Sep 23 - Sep 27
found 18 hours ago
Roundtrip non-stop flight included
New York (JFK) to Venice (VCE)
8.4/10 Very Good! (579 reviews)
The Hotel Ca' Alvise is a nice little hotel situated on a quiet canal a few bridges away from St. Mark's Square. The rooms are a bit dated but comfortable and DARK, which meant we all finally had a place in Italy to sleep past sunrise. We enjoyed dining nearby and walking further into Venice from here. The continental breakfast was great.

Reviewed on Jul 7, 2025

Hotel Marconi

Hotel Marconi

3 out of 5
Venice City Center
Save 100% on your flight
per person
Sep 15 - Sep 20
found 5 hours ago
Roundtrip non-stop flight included
New York (JFK) to Venice (VCE)
7.8/10 Good! (1,007 reviews)
Incredible experience. Every employee at the hotel were incredibly amazing and helpful. The location is fantastic, just a few steps from Rialto Bridge. The whole hotel offers Air conditioned in all rooms and common areas. The breakfast was amazing too. Water taxis and gondolas available in front of the hotel. We will definitely be back to this hotel.

Reviewed on Jul 1, 2025

Hotel Bisanzio

Hotel Bisanzio

4 out of 5
Castello
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9/10 Wonderful! (1,007 reviews)
Hotel is nice and location cannot be beat. Staff is friendly. We did not get our VIP perk promised by Expedia.

Reviewed on Jul 7, 2025

Nolinski Venezia - Evok Collection

Nolinski Venezia - Evok Collection

5 out of 5
Venice City Center
Save 100% on your flight
per person
Aug 9 - Aug 13
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9.8/10 Exceptional! (80 reviews)
Staff. Is wonderful.

Reviewed on Jul 7, 2025

Palazzina Grassi

Palazzina Grassi

5 out of 5
Venice City Center
Save 100% on your flight
per person
Sep 17 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
9/10 Wonderful! (203 reviews)
Great customer service! Beautiful hotel

Reviewed on Jul 4, 2025

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Dorsoduro featuring heritage architecture and a coastal town

Venice City Center

5 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

Find hotels in Venice City Center

Santa Croce Hotel Deals

Hotel Antiche Figure
Hotel Antiche Figure
3 out of 5
Santa Croce 687, Fondamenta S. Simeon Piccolo, Venice, VE
$200 nightly
The price is $228 total per night from Aug 4 to Aug 5
$228 total
Aug 4 - Aug 5
Total includes taxes and fees
9.6/10 Exceptional! (1,001 reviews)
"Great location. Would love to stay again."

Reviewed on Jul 7, 2025

Hotel Antiche Figure
Hotel Al Duca Di Venezia
Hotel Al Duca Di Venezia
3 out of 5
Fontego dei Turchi 1739 Santa Croce, Venice, VE
$146 nightly
The price is $169 total per night from Jul 20 to Jul 21
$169 total
Jul 20 - Jul 21
Total includes taxes and fees
9/10 Wonderful! (994 reviews)
"One of the most beautiful and charming hotels I’ve stayed in in a long time. The architecture, the furniture with the window drapes, beds, artwork, walls, Morano glass chandeliers in each room. The nice included semi private breakfast was a cherry on top. The staff was friendly, the location was ..."

Reviewed on Jul 2, 2025

Hotel Al Duca Di Venezia
Hotel Carlton on the Grand Canal
Hotel Carlton on the Grand Canal
4 out of 5
Sestiere Di Santa Croce 578, Venice, VE
Fully refundableReserve now, pay when you stay
$124 nightly
The price is $147 total per night from Jul 22 to Jul 23
$147 total
Jul 22 - Jul 23
Total includes taxes and fees
8.2/10 Very Good! (1,005 reviews)
"Great"

Reviewed on Jul 6, 2025

Hotel Carlton on the Grand Canal
See all 5,781 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Discover the most popular places to visit in Santa Croce

Fondaco dei Turchi

Fondaco dei Turchi

5/5(4 reviews)

You can browse the exhibits at Fondaco dei Turchi, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area.

Fondaco dei Turchi
#LifeatExpedia #Waterlust #GoldenHour #TroveOn #Architecture

Tolentini

Learn about the local history of Venice when you take a trip to Tolentini. Visit the area's stunning cathedral or amble around its marina.

Tolentini
Ca'Pesaro

Ca'Pesaro

You can browse the exhibits at Ca'Pesaro, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area.

Ca'Pesaro

Things to do

Venice: Leonardo Da Vinci Museum Entrance Ticket

Venice: Leonardo Da Vinci Museum Entrance Ticket

$9
per adult
74% of travellers recommend
Venice: Leonardo Da Vinci Museum Entrance Ticket
A day among the most beautiful mountains in the world, the Dolomites and Lake Braies

A day among the most beautiful mountains in the world, the Dolomites and Lake Braies

$242
per adult
100% of travellers recommend
A day among the most beautiful mountains in the world, the Dolomites and Lake Braies
Venice: St. Mark’s Basilica Skip-the-Line Tour & Gondola Ride Experience

Venice: St. Mark’s Basilica Skip-the-Line Tour & Gondola Ride Experience

$80
per adult
90% of travellers recommend
Venice: St. Mark’s Basilica Skip-the-Line Tour & Gondola Ride Experience
See all activities in Venice
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.