Santa Croce Vacations from $573

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Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including Rialto Bridge, St. Marks Basilica and St. Marks Square. Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.
B&B HOTEL Venezia Laguna

B&B HOTEL Venezia Laguna

3 out of 5
Price was $707, price is now $573 per person
$573
per person
Jan 16 - Jan 22
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Venice (VCE)
9/10 Wonderful! (54 reviews)
Newly built property, so everything is in top condition. Modern. Good amenities. Excellent breakfast. Helpful staff.

Reviewed on Nov 3, 2025

Hotel Gabrielli - Starhotels Collezione

Hotel Gabrielli - Starhotels Collezione

5 out of 5
Castello
Save 100% on your flight
Price was $2,884, price is now $2,139 per person
$2,139
per person
Dec 14 - Dec 20
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Venice (VCE)
10/10 Exceptional! (9 reviews)
Superb location and all facilities excellent. Roof terrace a fantastic asset

Reviewed on Oct 21, 2025

Kette Hotel

Kette Hotel

4 out of 5
Venice City Center
Price was $829, price is now $665 per person
$665
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Venice (VCE)
8.6/10 Excellent! (1,005 reviews)
No air conditioning! So hot! The room never cooled off. Couldn’t keep windows open due to risk of birds getting in the room. Lowest bed I’ve ever experienced. Staff was great. Water taxi pickup on checkout day was great! Private transportation services can’t use their dock, only companies the hotel arranges. Breakfast hours started late for tourist with early tours.

Reviewed on Oct 15, 2025

Ca' Pisani Hotel

Ca' Pisani Hotel

4.5 out of 5
Dorsoduro
Price was $1,009, price is now $822 per person
$822
per person
Dec 7 - Dec 12
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Venice (VCE)
9.4/10 Exceptional! (845 reviews)
Everything was great the only negative is my spa tub did not work.

Reviewed on Oct 26, 2025

Hotel Dell'Opera

Hotel Dell'Opera

3 out of 5
Venice City Center
Price was $985, price is now $806 per person
$806
per person
Jan 16 - Jan 22
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Venice (VCE)
9/10 Wonderful! (875 reviews)
Friendly staff, clean, safe, convenient

Reviewed on Oct 24, 2025

Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. Learn more about Santa Croce
Dorsoduro featuring heritage architecture and a coastal town

Venice City Center

5 out of top 10 points of interest in this area

Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water.

Find hotels in Venice City Center

Santa Croce Hotel Deals

Hotel Antiche Figure

Hotel Antiche Figure

3 out of 5
Santa Croce 687, Fondamenta S. Simeon Piccolo, Venice, VE
$151 nightly
The price is $175 total per night from Nov 18 to Nov 19
$175 total
Nov 18 - Nov 19
Total with taxes and fees
9.6/10 Exceptional! (1,021 reviews)
Clean room, super friendly staff especially David.

Reviewed on Nov 3, 2025

Hotel Antiche Figure
Hotel Canal Grande

Hotel Canal Grande

4 out of 5
Santa Croce 932, Campo San Simeone Profeta, Venice, VE
$140 nightly
The price is $165 total per night from Nov 19 to Nov 20
$165 total
Nov 19 - Nov 20
Total with taxes and fees
9.6/10 Exceptional! (1,004 reviews)
Everything is good

Reviewed on Nov 1, 2025

Hotel Canal Grande
Santa Chiara Hotel

Santa Chiara Hotel

4.5 out of 5
Santa Croce 548, Venice, VE
Fully refundableReserve now, pay when you stay
$199 nightly
The price is $230 total per night from Nov 11 to Nov 12
$230 total
Nov 11 - Nov 12
Total with taxes and fees
9.2/10 Wonderful! (299 reviews)
This Hotel was perfect. No walking bags long distances to hotels more centrally located. There are water taxis everywhere. Super convenient to the train station. The front desk scheduled excursions for us and gave suggestions that made our stay unforgettable. From the glass blowing manufacturers ...

Reviewed on Oct 29, 2025

Santa Chiara Hotel
See all 5,729 properties in Santa Croce
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Croce

Ca'Pesaro

Ca'Pesaro

You can browse the exhibits at Ca'Pesaro, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area.

Ca'Pesaro
Fondaco dei Turchi

Fondaco dei Turchi

5/5(4 reviews)

You can browse the exhibits at Fondaco dei Turchi, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the churches in the area.

Fondaco dei Turchi
#LifeatExpedia #Waterlust #GoldenHour #TroveOn #Architecture

Tolentini

Learn about the local history of Venice when you take a trip to Tolentini. Visit the area's churches or amble around its marina.

Tolentini

Things to do

Sidewalk flanked by colorful buildings in Burano

Murano & Burano Tour

$58
per adult
90% of travellers recommend
Murano & Burano Tour
Single gondola paddles down waterway in Venice

Classic 30 minutes Gondola Ride

$45
per traveler
Classic 30 minutes Gondola Ride
Half Day Murano and Burano Island Tour by Private Boat

Half Day Murano and Burano Island Tour by Private Boat

$32
per adult
88% of travellers recommend
Half Day Murano and Burano Island Tour by Private Boat
See all activities in Venice
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.