Title: Santa Croce Vacation Packages 2026 from $1,353 | Expedia.com

[Santa Croce Travel Guide](https://expedia.com/Venice-Santa-Croce.dx6046564)[Hotels in Santa Croce](https://expedia.com/Santa-Croce-Venice-Hotels.0-n6046564-0.Travel-Guide-Filter-Hotels)[Flights to Venice](https://expedia.com/Cheap-Flights-To-Venice.d179981.Travel-Guide-Flights)[Things to do in Venice](https://expedia.com/Things-To-Do-In-Venice.d179981.Travel-Guide-Activities)[Car Rentals in Santa Croce](https://expedia.com/Car-Rentals-In-Santa-Croce.d6046564.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6046564/aae7b138-5455-4af7-94dd-26683edbe0d8.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santa Croce Vacations from $1,353

## Book a Hotel + Flight or Car together to unlock savings

## Your Santa Croce Vacation

Discover the best that Santa Croce offers with a Santa Croce vacation package. From its culture to every other thing that makes it special, this neighborhood will charm you from beginning to end. When it's time to take in the sights, you'll find loads of popular attractions nearby including [Rialto Bridge](https://www.expedia.com/Rialto-Bridge-Venice-City-Center.d508806.Vacation-Attraction), [St. Marks Basilica](https://www.expedia.com/St-Marks-Basilica-Venice-City-Center.d503202.Vacation-Attraction) and [St. Marks Square](https://www.expedia.com/St-Marks-Square-San-Marco.d503200.Vacation-Attraction). Visit one, two or more during your trip to Santa Croce. Don't just dream it — do it! Lock in your ideal Santa Croce vacation with Expedia and experience travel your way.

## The Latest Santa Croce Vacation Packages

Price found within the past 48 hours. Click for updated prices.

![Hotel Olimpia Venice, BW Signature Collection](https://images.trvl-media.com/lodging/2000000/1210000/1201800/1201731/a0a5a34c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Olimpia Venice, BW Signature Collection

Santa Croce

$1,353

per person

Apr 14 - Apr 17

found 12 hours ago

Roundtrip flight included

Philadelphia (PHL) to Venice (VCE)

9.6/10 Exceptional! (1,003 reviews)

Very friendly and clean

Reviewed on Mar 4, 2026

![Unahotels Ala Venezia - Adults Only](https://images.trvl-media.com/lodging/1000000/870000/863900/863862/db679db9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Unahotels Ala Venezia - Adults Only

Venice City Center

$1,408

per person

Apr 14 - Apr 17

found 12 hours ago

Roundtrip flight included

Philadelphia (PHL) to Venice (VCE)

9/10 Wonderful! (1,000 reviews)

Great location. Steps from a water bus stop to the airport and train station and close to everything else. If you are like me and don’t pack body wash, shampoo or conditioner when traveling, just know that there was only body wash in the shower. No big deal, just something to be aware of. Room was a good size and was clean and quiet as well.

Reviewed on Mar 8, 2026

![Eurostars Residenza Cannaregio Hotel](https://images.trvl-media.com/lodging/1000000/990000/982000/981929/fa4b0d39_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Eurostars Residenza Cannaregio Hotel

Cannaregio

$1,456

per person

May 28 - Jun 1

found 1 day ago

Roundtrip flight included

Boston (BOS) to Venice (VCE)

8.6/10 Excellent! (1,003 reviews)

Good Service Good breakfast

Reviewed on Feb 18, 2026

![Ca' Sagredo](https://images.trvl-media.com/lodging/2000000/1600000/1593300/1593284/1e825745_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Ca' Sagredo

Venice City Center

Save 100% on your flight

$2,864

per person

Apr 26 - May 2

found 22 hours ago

Roundtrip flight included

Philadelphia (PHL) to Venice (VCE)

9.2/10 Wonderful! (479 reviews)

The hotel is really beautifully decorated, keeping up with Venizian style, spacious and clean. The reason for lower rating are the following: 1/no complementary water in the room (small water bottles available in mini bar for €8!). Water is such a basic necessity I would have expected from a 5\* hotlel, 2/ no kettle not coffee machine in rooms, 3/ Cleaning staff was entering our room every evening without knocking and didn't speak English.

Reviewed on Mar 2, 2026

![Venezia Palazzo Barocci](https://images.trvl-media.com/lodging/1000000/990000/982500/982473/0dc402e9_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Venezia Palazzo Barocci

Venice City Center

$2,173

per person

Apr 20 - Apr 23

found 1 day ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to Venice (VCE)

9.2/10 Wonderful! (965 reviews)

The Staff were very welcoming and friendly and super helpful. Offering help with destinations, places to eat, directions My daughter was really ill with a heavy cold one night so I asked for specific room service and they were brilliant. Hotel is in perfect position Super quiet and central to everything

Reviewed on Mar 11, 2026

## Where to stay in Santa Croce

Find the best Santa Croce areas and neighborhoods for the activities you enjoy most. [Learn more about Santa Croce](https://expedia.com/Venice-Santa-Croce.dx6046564)

![Dorsoduro featuring heritage architecture and a coastal town](https://images.trvl-media.com/place/6049646/e3c4afd6-1e37-4d4e-8f71-1bcc2b96f99a.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Venice City Center

5 out of top 10 points of interest in this area

 Discover an abundance of architectural monuments and great art by grandmasters in the heart of an Italian city built on water. 

[Find hotel + flight trips in Venice City Center](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Venice%20City%20Center&DestID=6222433&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![San Marco featuring kayaking or canoeing and a river or creek](https://images.trvl-media.com/place/6005315/7aeaf7e3-bd50-45a9-8773-938edd990a22.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Marco

1 out of top 10 points of interest in this area

4.5/5(1,933 area reviews)

 In the heart of Venice, this densely built area boasts iconic attractions like St Mark's Square, Saint Mark's Basilica, and the Doge's Palace. Find numerous hotels, banks, and high-end shops amid the bustling tourist scene. 

[Find hotel + flight trips in San Marco](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Marco&DestID=6005315&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![San Polo featuring heritage architecture and a bay or harbor](https://images.trvl-media.com/place/6005317/25bd17a5-5e0d-4cf6-a192-3237fd41e600.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Polo

4.5/5(302 area reviews)

 Smallest and most central sestiere, San Polo boasts churches in the west, palaces in the east, and iconic attractions like Rialto Bridge and Scuola Grande di San Rocco. 

[Find hotel + flight trips in San Polo](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=San%20Polo&DestID=6005317&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Venetian Ghetto featuring heritage architecture, boating and a bridge](https://images.trvl-media.com/place/506748/daf8052e-57f2-496e-8cde-07f79dc4d86c.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Cannaregio

4.5/5(1,000 area reviews)

 Explore historic churches like Santa Maria di Nazareth and Santa Maria dei Miracoli, or admire stunning palazzos such as Ca' d'Oro and Ca' Vendramin Calergi. Enjoy morning markets, local shops, and quaint cafés in this residential, peaceful district. 

[Find hotel + flight trips in Cannaregio](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Cannaregio&DestID=6005309&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

![Dorsoduro showing a river or creek and a bridge](https://images.trvl-media.com/place/6049646/4cff27d0-931f-4dbe-8459-aa94f48a7e6e.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Dorsoduro

4.5/5(423 area reviews)

 Boasting the highest land areas in Venice, this sestiere features the stunning Basilica of Santa Maria della Salute and the picturesque Zattere quay. Easily connect to San Marco via Ponte dell'Accademia. 

[Find hotel + flight trips in Dorsoduro](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Dorsoduro&DestID=6049646&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods)

## Santa Croce Hotel Deals

![Papadopoli Hotel Venezia - MGallery Collection](https://images.trvl-media.com/lodging/1000000/10000/2600/2506/c5b58019_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Papadopoli Hotel Venezia - MGallery Collection

Santa Croce 245 Venice VE

Fully refundableReserve now, pay when you stay

$208 nightly

$239 total

Mar 18 - Mar 19

Total with taxes and fees

9.2/10 Wonderful! (1,000 reviews)

.

Reviewed on Feb 24, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&selected=2506&PinnedHotelID=2506&HadPinnedHotel=true&regionId=6046564)

![Hotel Canal Grande](https://images.trvl-media.com/lodging/3000000/2930000/2921400/2921301/42cd722c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Canal Grande

Santa Croce 932 Venice VE

Fully refundableReserve now, pay when you stay

$157 nightly

$184 total

Mar 17 - Mar 18

Total with taxes and fees

9.6/10 Exceptional! (1,001 reviews)

Awesome property great location

Reviewed on Mar 6, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F17%2F2026&endDate=3%2F18%2F2026&selected=2921301&PinnedHotelID=2921301&HadPinnedHotel=true&regionId=6046564)

![Palazzo Marcello Hotel al Sole](https://images.trvl-media.com/lodging/1000000/530000/527200/527182/156c9c11_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Palazzo Marcello Hotel al Sole

Santa Croce 134/136 Venice VE

Fully refundableReserve now, pay when you stay

$138 nightly

$160 total

Mar 15 - Mar 16

Total with taxes and fees

8.6/10 Excellent! (843 reviews)

Very helpful and friendly staff in a beautiful boutique hotel.

Reviewed on Feb 22, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&selected=527182&PinnedHotelID=527182&HadPinnedHotel=true&regionId=6046564)

[See all 6,121 properties in Santa Croce](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&regionId=6046564)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

### Discover the most popular places to visit in Santa Croce

![moderne Fußgängerbrücke über den Canal Grande Venedig](https://images.trvl-media.com/place/508730/b2d959cf-6c5c-4a63-a47f-d70632f3e6f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Piazzale Roma

4.5/5(626 reviews)

You can learn about the local history of Venice during your trip to a top site like Piazzale Roma. Stroll along the marina or visit the stunning cathedral in the area. 

[](https://expedia.com/Piazzale-Roma-Santa-Croce.d508730.Vacation-Attraction)

![Venedig / Ca’ Pesaro](https://images.trvl-media.com/place/503188/6c3c6a94-0d9d-4320-bbf3-b55e620c3717.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Ca'Pesaro

You can browse the exhibits at Ca'Pesaro, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area. 

[](https://expedia.com/CaPesaro-Venice-City-Center.d503188.Vacation-Attraction)

![Fondaco dei Turchi am Canal Grande in Venedig, Italien](https://images.trvl-media.com/place/503193/457d876f-b87e-4e60-88e6-ec8899771442.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Fondaco dei Turchi

5/5(4 reviews)

You can browse the exhibits at Fondaco dei Turchi, a museum with a storied past, during your trip to Venice. Stroll along the marina or visit the stunning cathedral in the area. 

[](https://expedia.com/Fondaco-Dei-Turchi-Venice-City-Center.d503193.Vacation-Attraction)

### Things to do

![Skip-the-Line: Doge’s Palace & St Mark’s Basilica Small-Group Guided Tour](https://mediaim.expedia.com/localexpert/2547574/da851fe1-33fd-49bc-9ba4-1fb3db4926b4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Skip-the-Line: Doge’s Palace & St Mark’s Basilica Small-Group Guided Tour

$81

per adult

**96%** of travellers recommend

[](https://expedia.com/things-to-do/skip-the-line-doges-palace-st-marks-basilica-small-group-guided-tour.a2547574.activity-details)

![Sidewalk flanked by colorful buildings in Burano](https://mediaim.expedia.com/localexpert/450244/43bb9b68-88ca-4bc7-b9c3-cddfe7f968bb.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Murano & Burano Tour

$25

per adult

**90%** of travellers recommend

[](https://expedia.com/things-to-do/murano-burano-tour.a450244.activity-details)

![Venice and Verona from Milan in one day!](https://mediaim.expedia.com/localexpert/2458289/24845d17-92d2-4d39-9323-ec796eb1a24c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Venice and Verona in one day by Train from Milan

$188

per adult

**90%** of travellers recommend

[](https://expedia.com/things-to-do/venice-and-verona-in-one-day-by-train-from-milan.a2458289.activity-details)

[See all activities in Venice](https://expedia.com/things-to-do/search?rid=6046564)

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.