Title: Santa Cruz Mixtepec Vacation Rentals from $86: Search Short-Term Rentals | Expedia.com

[Hotels in Santa Cruz Mixtepec](https://expedia.com/Santa-Cruz-Mixtepec-Hotels.d553248635640628853.Travel-Guide-Hotels)[Flights to Santa Cruz Mixtepec](https://expedia.com/Cheap-Flights-To-Santa-Cruz-Mixtepec.d553248635640628853.Travel-Guide-Flights)[Car Rentals in Santa Cruz Mixtepec](https://expedia.com/Car-Rentals-In-Santa-Cruz-Mixtepec.d553248635640628853.Car-Rental-Guide)[Santa Cruz Mixtepec Vacation Packages](https://expedia.com/Santa-Cruz-Mixtepec.d553248635640628853.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://a.travel-assets.com/travel-assets-manager/32a5a1b7-682e-4c22-a8ab-4b736795e0ea/expedia_fallback.webp?impolicy=fcrop&w=1200&h=500&q=medium)

## Check prices for these dates

In two weeks

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635640628853&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=553248635640628853&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=553248635640628853&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=553248635640628853&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Cruz Mixtepec vacation rentals

![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118050000/118049400/118049310/3e62fd84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/119000000/118050000/118049400/118049310/43db431c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/119000000/118050000/118049400/118049310/9a113658.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/119000000/118050000/118049400/118049310/110ee511.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cottage in Villa de Zaachila

[](https://www.expedia.com/Villa-De-Zaachila-Hotels-Charming-1-Bedroom-Cottage-In-Villa-De-Zaachila.h118049310.Hotel-Information)

$85 nightly

$98 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Villa-De-Zaachila-Hotels-Charming-1-Bedroom-Cottage-In-Villa-De-Zaachila.h118049310.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/120000000/119700000/119691700/119691685/3c0be33a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Towels, soap, toilet paper](https://images.trvl-media.com/lodging/120000000/119700000/119691700/119691685/1cba0365.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/120000000/119700000/119691700/119691685/5c8f97b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/120000000/119700000/119691700/119691685/ef08053b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in Villa de Zaachila

[](https://www.expedia.com/Villa-De-Zaachila-Hotels-Private-Cabin-In-Oaxaca-With-Bathtub.h119691685.Hotel-Information)

10/10

Exceptional

(1 review)

$99 nightly

$114 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Villa-De-Zaachila-Hotels-Private-Cabin-In-Oaxaca-With-Bathtub.h119691685.Hotel-Information)

![Living area](https://images.trvl-media.com/lodging/125000000/124740000/124738100/124738024/2bf7af57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/125000000/124740000/124738100/124738024/7222db0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/125000000/124740000/124738100/124738024/7c01b6a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/125000000/124740000/124738100/124738024/d12f7010.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz Xoxocotlán

[](https://www.expedia.com/Oaxaca-Hotels-Vrbo-Property.h124738024.Hotel-Information)

$103 nightly

$120 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Oaxaca-Hotels-Vrbo-Property.h124738024.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/115000000/114880000/114876400/114876394/d68497d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/115000000/114880000/114876400/114876394/15a31ce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114880000/114876400/114876394/6dbde2d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/115000000/114880000/114876400/114876394/6474ab89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in San Agustín de las Juntas

[](https://www.expedia.com/Oaxaca-Hotels-Enchanting-2-Bedroom-Apartment-With-WiFi-In-San-Agustin-De-Las-Juntas.h114876394.Hotel-Information)

$92 nightly

$106 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Oaxaca-Hotels-Enchanting-2-Bedroom-Apartment-With-WiFi-In-San-Agustin-De-Las-Juntas.h114876394.Hotel-Information)

![Stovetop, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/115000000/114450000/114440500/114440467/94c61c38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114450000/114440500/114440467/44315b40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, towels, soap, toilet paper](https://images.trvl-media.com/lodging/115000000/114450000/114440500/114440467/7a61f4cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/115000000/114450000/114440500/114440467/0ce91fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz Xoxocotlán

[](https://www.expedia.com/Oaxaca-Hotels-Vrbo-Property.h114440467.Hotel-Information)

$92 nightly

$106 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Oaxaca-Hotels-Vrbo-Property.h114440467.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/58000000/57930000/57920300/57920222/f281c677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/58000000/57930000/57920300/57920222/cdb87ea7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/58000000/57930000/57920300/57920222/dea902d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/58000000/57930000/57920300/57920222/759e5ce4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabin in San Martin Lachilá

[](https://www.expedia.com/Heroica-Ciudad-De-Ejutla-De-Crespo-Hotels-Cantarranas-Ranch.h57920222.Hotel-Information)

10/10

Exceptional

(1 review)

"Very good "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

FERNANDO

$74 nightly

$86 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Heroica-Ciudad-De-Ejutla-De-Crespo-Hotels-Cantarranas-Ranch.h57920222.Hotel-Information)

![4 bedrooms, iron/ironing board, internet, bed sheets](https://images.trvl-media.com/lodging/119000000/118960000/118953200/118953128/b7788637.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/119000000/118960000/118953200/118953128/9d7c7f70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/119000000/118960000/118953200/118953128/9adb4982.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/119000000/118960000/118953200/118953128/92c353a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Vacation Home in Santa Cruz Xoxocotlán

[](https://www.expedia.com/Oaxaca-Hotels-Your-Shelter-Near-Arrazola.h118953128.Hotel-Information)

$101 nightly

$118 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Oaxaca-Hotels-Your-Shelter-Near-Arrazola.h118953128.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/109000000/108730000/108720600/108720591/78678e99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/109000000/108730000/108720600/108720591/122b8408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/109000000/108730000/108720600/108720591/2568021e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor spa tub](https://images.trvl-media.com/lodging/109000000/108730000/108720600/108720591/d0410608.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Santa Cruz Xoxocotlán

[](https://www.expedia.com/Oaxaca-Hotels-Espectacular-Y-Moderno-Apartamento.h108720591.Hotel-Information)

$163 nightly

$191 total

Mar 2 - Mar 3

Total with taxes and fees

[](https://www.expedia.com/Oaxaca-Hotels-Espectacular-Y-Moderno-Apartamento.h108720591.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16&regionId=553248635640628853&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## 

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Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_553248635640628853)

## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico&regionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=CABIN)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico&regionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico&regionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=APARTMENT)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz+Mixtepec%2C+Oaxaca%2C+Mexico&regionId=553248635640628853&latLong=16.789997%2C-96.905339&adults=2&startDate=2026-05-30&d1=2026-05-30&endDate=2026-06-02&d2=2026-06-02&lodging=COTTAGE)

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## Top Santa Cruz Mixtepec Hotel Reviews

![Maria Ines Hotel Suite](https://images.trvl-media.com/lodging/20000000/19120000/19114500/19114426/d5d7f7f0_y.jpg)

### Maria Ines Hotel Suite

10/10 Excellent

"Clean and comfortable. Service great. Our second stay. "

[](https://expedia.com/Oaxaca-Hotels-Maria-Ines-Hotel-Suite.h19114426.Hotel-Information)

![Motel Las Maravillas](https://images.trvl-media.com/lodging/28000000/27160000/27156300/27156240/f3783978_y.jpg)

### Motel Las Maravillas

2/10 Terrible

"Dirty rooms, broken washrooms, terrible linen and towels. "

[](https://expedia.com/Oaxaca-Hotels-Motel-Las-Maravillas.h27156240.Hotel-Information)

![OYO Hotel Rey David, Oaxaca](https://images.trvl-media.com/lodging/47000000/46340000/46331800/46331727/fc660c33_y.jpg)

### OYO Hotel Rey David, Oaxaca

8/10 Good

"Clean room but had to request a towel. Otherwise everything was perfect particularly the bar next door and its very helpful and friendly owner Manuel."

[](https://expedia.com/Ocotlan-De-Morelos-Hotels-Hotel-Rey-David.h46331727.Hotel-Information)

![Motel Puerta del Cielo](https://images.trvl-media.com/lodging/40000000/39220000/39212000/39211936/53e2a48d_y.jpg)

### Motel Puerta del Cielo

10/10 Excellent

"Good "

[](https://expedia.com/Oaxaca-Hotels-Motel-Puerta-Del-Cielo.h39211936.Hotel-Information)

![Hotel Guivá Aeropuerto](https://images.trvl-media.com/lodging/37000000/36700000/36699000/36698970/d4f10f9d_y.jpg)

### Hotel Guivá Aeropuerto

10/10 Excellent

"The room was clean and tidy, the staff friendly. If you want an easy place to stay before flying out of Oaxaca, this airport hotel is just 5 minutes away. The staff will order a taxi for you. "

[](https://expedia.com/Oaxaca-Hotels-Hotel-Guiva-Aeropuerto.h36698970.Hotel-Information)

![Villas Horizonte Oaxaca](https://images.trvl-media.com/lodging/104000000/103820000/103813400/103813375/f9b3d0b4_y.jpg)

### Villas Horizonte Oaxaca

8/10 Good

"Rooms are nice and clean, they gave me a room without air conditioned but I told them I booked a room with AC and they gave me another room. The hotel is out of downtown, no noise, streets are not paved in that area. It is a good chooce If you don’t want to expend too much money. "

[](https://expedia.com/Santa-Maria-Coyotepec-Hotels-Villas-Horizonte-Oaxaca.h103813375.Hotel-Information)

## Find out more about Santa Cruz Mixtepec

**Everything you need to know about Santa Cruz Mixtepec vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz Mixtepec vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz Mixtepec vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Santa Cruz Mixtepec vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Santa Cruz Mixtepec. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz Mixtepec in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $86 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Santa Cruz Mixtepec rentals**

At Expedia, we put the best Santa Cruz Mixtepec vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz Mixtepec rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz Mixtepec vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz Mixtepec. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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## Frequently asked questions

### Can I find vacation rentals in Santa Cruz Mixtepec?

### What are some of the best vacation home rentals that Santa Cruz Mixtepec has to offer?

### What’s there to see and do in Santa Cruz Mixtepec?

### What’s a vacation rental in Santa Cruz Mixtepec like?