Santa Cruz Vacation Rentals

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Dec 5 - Dec 7
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Jan 16 - Jan 18
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Vacation Rentals in Santa Cruz

1 bedroom, laptop workspace, free WiFi
Colchagua Tiny Lodge

Colchagua Tiny Lodge

3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (3)
"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10. "
United States
Trisha
$197 nightly
The price is $197
Dec 1 - Dec 2
Colchagua Tiny Lodge
Property grounds
The ambush. Field and comfort

The ambush. Field and comfort

Santa Cruz
$165 nightly
The price is $192
Nov 24 - Nov 25
The ambush. Field and comfort
Property grounds
Corazon de Colchagua Sta Cruz Cabin

Corazon de Colchagua Sta Cruz Cabin

Nancagua
$78 nightly
The price is $81
Nov 24 - Nov 25
Corazon de Colchagua Sta Cruz Cabin
Dining
House in a natural setting

House in a natural setting

Curico
$92 nightly
The price is $106
Nov 29 - Nov 30
House in a natural setting
Exterior
Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)

Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)

2.0 star property
Chimbarongo
$69 nightly
The price is $69
Nov 24 - Nov 25
Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)
Living area
The most comfortable apartment in San Fernando

The most comfortable apartment in San Fernando

San Fernando
$145 nightly
The price is $145
Nov 24 - Nov 25
The most comfortable apartment in San Fernando
Exterior detail
Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua

San Vicente de Taguatagua
$78 nightly
The price is $78
Nov 24 - Nov 25
Hostel Turismo San Vicente Tagua Tagua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

La Perla Hotel

La Perla Hotel

10/10 Excellent
"Review for La Perla Hotel La Perla is a beautiful and peaceful place to stay. The property is private, deeded, and very well maintained, with landscaping that makes the whole space feel calm and inviting. My room was spotless, spacious, and everything worked exactly as it should. The shower had strong water pressure, which I appreciated after a long day of wine tasting. The hotel has a nice pool, a breakfast area in the mornings, and even offers wines you can purchase on site. It is quiet, isolated, and very secure, so you really feel like you’re getting away from everything. The customer service team was great the entire time and made the stay even better. Highly recommend if you want a clean, comfortable, and relaxing spot in the region."
Arnulfo 2-night trip
Posted 5 days ago
La Perla Hotel

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, there are vacation rentals in Santa Cruz close to Colchagua Campo y Vino, or you can choose a more secluded option if you want a relaxing stay. Our travelers say Santa Cruz has a good selection of wineries and the restaurants. Make sure you have time to check out the local tours and casinos during your trip.

What's the top vacation rental that Santa Cruz has to offer?

Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Our travelers also rate The ambush. Field and comfort as a favorite home for rent in Santa Cruz.

What can I see and do in Santa Cruz?

Cultural attractions include Museo de Colchagua, whereas Millahue Valley is a spot to enjoy nature. Colchagua Campo y Vino and Casino Colchagua are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private properties you can stay in for several days or longer in Santa Cruz. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family getaway.