Santa Cruz Vacations from $416
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Your Santa Cruz Vacation
Say bye-bye to the worries of planning and hello to a Santa Cruz vacation package. With your travel details organized before you go, you can focus on discovering the best of this city, starting with Tlalnepantla Centro, which is great for bars and pubs, shopping and dining. If taking in the sights is a priority during your trip to Santa Cruz, make sure you find your way to well-known attractions like Xochitla Ecological Park and Temple of San Francisco Javier. Whoever you're taking time off with and whatever the size of your budget, your dream Santa Cruz vacation is just a few clicks away with Expedia.
The Latest Santa Cruz vacation packages
Price found within the past 48 hours. Click for updated prices.
Hacienda Peña Pobre
Tlalpan
Price was $1,648, price is now $880 per person
$880
per person
Aug 18 - Aug 23
found 1 day ago
Roundtrip non-stop flight included
Burbank (BUR) to Mexico City (MEX)
9.6/10 Exceptional! (806 reviews)
Very clean and quiet place, pleasant breakfasts and within walking distance to the beautiful park Bosque de Tlalpan, and very close to the Perisur shopping center and other interesting places. The staff is great and very helpful. Very enjoyable stay.
Reviewed on Jul 8, 2026
Alteza Polanco
Polanco
Save 100% on your flight
Price was $1,706, price is now $932 per person
$932
per person
Sep 19 - Sep 26
found 2 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
8.6/10 Excellent! (668 reviews)
Clean and as expected! Staff was polite and professional. The room was cozy and a/c super cold. It was on the very edge of Polanco but still very walkable and centrally located. My only complaint is that it took a bit of tries to figure out the hot and cold water in the shower but figured it out.
Reviewed on Jun 16, 2026
Roma Nueve Dos Hotel Boutique
Roma Norte
Save 100% on your flight
Price was $1,963, price is now $1,107 per person
$1,107
per person
Aug 18 - Aug 23
found 7 hours ago
Roundtrip non-stop flight included
Burbank (BUR) to Mexico City (MEX)
9/10 Wonderful! (12 reviews)
The rooms are gorgeous. Staff was amazing. Couldn’t ask for a better location. The bar isn’t open quite yet but will come back to check out. I can’t say enough about the bed, sheets, mattress, comforter and towels. We had an amazing sleep. I left asking for the brand so I could purchase. My next visit to CDMX I will be staying here!
Reviewed on Jul 12, 2026
Santa Cruz Hotel Deals
InterContinental Presidente Mexico City by IHG
Campos Eliseos 218 Mexico City
Fully refundable
$347 nightly
The price is $415 total per night from Jul 24 to Jul 25
$415 total
Jul 24 - Jul 25
Total with taxes and fees
9.4/10 Exceptional! (2,459 reviews)
"Todo excelente, desde las personas a los cuartos y lo mejor la ubicacion"
Reviewed on Jul 12, 2026
Downtown Treasure Place
85 Marte Guerrero Mexico City CDMX
Fully refundableReserve now, pay when you stay
$37 nightly
The price is $45 total per night from Jul 14 to Jul 15
$45 total
Jul 14 - Jul 15
Total with taxes and fees
8.8/10 Excellent! (848 reviews)
"Thanks for everything"
Reviewed on Jun 24, 2026
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
$269 nightly
The price is $322 total per night from Jul 26 to Jul 27
$322 total
Jul 26 - Jul 27
Total with taxes and fees
9.4/10 Exceptional! (1,465 reviews)
"Great location downtown, great staff who are very friendly. Very nice restaurant"
Reviewed on Jul 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Cruz Vacation Packages
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | Mexican pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Mexico City Intl. Airport (MEX) |
Population | 2,000 |
Top Sights | Xochitla Ecological Park and Temple of San Francisco Javier |
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Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
