Santa Cruz Vacations from $911
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Your Santa Cruz Vacation
Say bye-bye to the worries of planning and hello to a Santa Cruz vacation package. With your travel details organized before you go, you can focus on discovering the best of this city, starting with Tlalnepantla Centro, which is great for bars and pubs, shopping and dining. If taking in the sights is a priority during your trip to Santa Cruz, make sure you find your way to well-known attractions like Xochitla Ecological Park and Temple of San Francisco Javier. Whoever you're taking time off with and whatever the size of your budget, your dream Santa Cruz vacation is just a few clicks away with Expedia.
The Latest Santa Cruz vacation packages
Price found within the past 48 hours. Click for updated prices.
Colima 71 Casa de Arte Hotel
Roma Norte
$1,467
per person
Dec 3 - Dec 6
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.8/10 Exceptional! (53 reviews)
Superb.
One of the best (if not the best) boutique hotels I’ve ever stayed in.
All the space is exquisitely designed. The food is glorious but it’s the staff what makes it absolutely outstanding.
Yes you can stay in so many other different small, boutique, design-forward hotels in CDMX, but know, you’ll be missing out.
Reviewed on Sep 13, 2026
Roma Nueve Dos Hotel Boutique
Roma Norte
$1,042
per person
Jan 13 - Jan 17
found 1 day ago
Roundtrip flight included
Dallas (DFW) to Mexico City (MEX)
9.6/10 Exceptional! (39 reviews)
Everything was wonderful. The staff was lovely, the room beautiful, and the rooftop bar had great drinks. The location is very central and walkable.
Reviewed on Oct 26, 2026
Santa Cruz Hotel Deals
InterContinental Presidente Mexico City by IHG
Campos Eliseos 218 Mexico City
$492 nightly
$588 total
Nov 24 - Nov 25
Total with taxes and fees
9.4/10 Exceptional! (2,481 reviews)
"The hotel was wonderful. Breakfast was very good. The room was a bit small, overlooking the park. We had a great time staying…. Wish we were there longer"
Reviewed on Oct 26, 2026
Casa Olea
C. de Francisco Díaz Covarrubias Mexico City CDMX
Fully refundableReserve now, pay when you stay
$55 nightly
$65 total
Nov 24 - Nov 25
Total with taxes and fees
9.4/10 Exceptional! (1,002 reviews)
"It’s my second time booking this hotel. The staff is friendly and helpful. The beds are comfortable and you can actually sleep. Wish security and the staff made sure that quiet hours more closely observed. Other guests tend to not know how to handle themselves sometimes and they violate quiet hours. ..."
Reviewed on Oct 24, 2026
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco Mexico City
Fully refundableReserve now, pay when you stay
$343 nightly
$410 total
Nov 23 - Nov 24
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Cruz Vacation Packages
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | Mexican pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Mexico City Intl. Airport (MEX) |
Population | 2,000 |
Top Sights | Xochitla Ecological Park and Temple of San Francisco Javier |
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Frequently asked questions
How much does a Santa Cruz vacation package cost?
Offering excellent value package deals from $911 on Expedia, you'll be pleasantly surprised at how much a vacation to Santa Cruz costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa Cruz?
If you're looking to snag a cheap Santa Cruz vacation package, consider planning a trip in June, October and December. You'll usually find better rates on accommodations and flights during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Santa Cruz?
With a well-organized travel plan, you can easily tick off the main Santa Cruz sights in a handful of days. But if you'd like to explore off the beaten track or take day trips, consider booking your Santa Cruz vacation for longer.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is a breeze with Expedia. Once you've entered your destination and travel dates under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are often lower.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, hotel and flight into one great-value price and enjoy significant savings. You'll usually land a better deal than booking each component individually. And you'll still enjoy the freedom to create a customized Santa Cruz vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Cruz?
If you're planning a spontaneous Santa Cruz trip, browse our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can land incredible deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
Jet off on your perfect escape to Santa Cruz with our Book Now, Pay Later vacations. There's no need to save up or wait for the next payday — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans let you spread the total cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily stay on budget and snap up bargains before they disappear.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
