Title: Top 10 Hotels in Santa Cruz from $20 - Competitive Prices | Expedia.com [Vacation Rentals in Santa Cruz](https://expedia.com/Santa-Cruz-Vacation-Rentals.d553248635975856606.Travel-Guide-VacationRentals)[Flights to Santa Cruz](https://expedia.com/Cheap-Flights-To-Santa-Cruz.d553248635975856606.Travel-Guide-Flights)[Car Rentals in Santa Cruz](https://expedia.com/Car-Rentals-In-Santa-Cruz.d553248635975856606.Car-Rental-Guide)[Santa Cruz Vacation Packages](https://expedia.com/Santa-Cruz.d553248635975856606.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Family friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&travelerType=family_friendly) Pool [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&amenities=PETS) Apart hotel [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&lodging=APART_HOTEL) Spa [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&amenities=SPA_ON_SITE) Hot tub [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&amenities=HOT_TUB) Apart­ment [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&lodging=APARTMENT) Condo [](https://www.expedia.com/Hotel-Search?destination=Santa+Cruz%2C+Tepotzotl%C3%A1n%2C+State+of+Mexico%2C+Mexico®ionId=553248635975856606&latLong=19.693897%2C-99.259165&adults=2&startDate=2026-04-04&d1=2026-04-04&endDate=2026-04-06&d2=2026-04-06&lodging=CONDO) ## Check prices for these dates Tonight [Mar 21 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635975856606&startDate=2026-03-21&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=553248635975856606&startDate=2026-03-22&endDate=2026-03-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=553248635975856606&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=553248635975856606&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Outdoor treatment areas, sauna, body treatments, aromatherapy](https://images.trvl-media.com/lodging/17000000/16410000/16403800/16403716/bf311b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/17000000/16410000/16403800/16403716/4ffdba5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Porch](https://images.trvl-media.com/lodging/17000000/16410000/16403800/16403716/545b28bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/17000000/16410000/16403800/16403716/308d603b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Morada Tepotzotlan Boutique & Spa [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-La-Morada-Tepotzotlan-Boutique-Spa.h16403716.Hotel-Information) Tepotzotlán 7.8/10 Good (41 reviews) "na" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Karina Ponce [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-La-Morada-Tepotzotlan-Boutique-Spa.h16403716.Hotel-Information) ![Building design](https://images.trvl-media.com/lodging/9000000/8970000/8964100/8964075/dde8d422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite | Pillowtop beds, in-room safe, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/9000000/8970000/8964100/8964075/0c1f1d42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/9000000/8970000/8964100/8964075/a23cf3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/9000000/8970000/8964100/8964075/b57b22f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Finca Las Hortensias [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-Hotel-Finca-Las-Hortensias.h8964075.Hotel-Information) Tepotzotlán 8.4/10 Very Good (188 reviews) "Nice rooms and grounds." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond $56 nightly $69 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-Hotel-Finca-Las-Hortensias.h8964075.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/106000000/105590000/105586300/105586247/4e607697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/106000000/105590000/105586300/105586247/41c39242.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105590000/105586300/105586247/977b041a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Bathroom](https://images.trvl-media.com/lodging/106000000/105590000/105586300/105586247/d2addd85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villa Granada [](https://www.expedia.com/Tecamac-Hotels-Villa-Granada.h105586247.Hotel-Information) Tecamac 9.0/10 Wonderful (58 reviews) "One of the best Hotels for that area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GUSTAVO $40 nightly $48 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Tecamac-Hotels-Villa-Granada.h105586247.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/100000000/99810000/99801300/99801294/e4deedbb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Living area | Smart TV, computer monitors](https://images.trvl-media.com/lodging/100000000/99810000/99801300/99801294/583f0424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Wardrobe](https://images.trvl-media.com/lodging/100000000/99810000/99801300/99801294/4a156e9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99810000/99801300/99801294/c078e0df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Verticca Hotel [](https://www.expedia.com/Tecamac-Hotels-Verticca-Hotel.h99801294.Hotel-Information) Ojo de Agua 9.2/10 Wonderful (274 reviews) "Everything was great we like the place." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gilberto [](https://www.expedia.com/Tecamac-Hotels-Verticca-Hotel.h99801294.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/81000000/80950000/80942000/80941953/357806a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/81000000/80950000/80942000/80941953/b0a2d074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, Kitchen (Living , Meeting, Billiards) | Minibar, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/81000000/80950000/80942000/80941953/a85ef77a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/81000000/80950000/80942000/80941953/da2102b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG [](https://www.expedia.com/Zumpango-Hotels-Holiday-Inn-Hotel-And-Suites-Mexico-Felipe-Angeles-Airport.h80941953.Hotel-Information) Zumpango 9.4/10 Exceptional (1,094 reviews) "Good, clean, close to airport " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darylle $130 nightly $156 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/Zumpango-Hotels-Holiday-Inn-Hotel-And-Suites-Mexico-Felipe-Angeles-Airport.h80941953.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/125000000/124820000/124818800/124818797/c68d972d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Building design](https://images.trvl-media.com/lodging/125000000/124820000/124818800/124818797/51805b56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/125000000/124820000/124818800/124818797/14f90915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/125000000/124820000/124818800/124818797/d262153b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Único La Villa [](https://www.expedia.com/Mexico-City-Hotels-La-Villa-Hotel.h124818797.Hotel-Information) Gustavo A. Madero 7.0/10 Good (34 reviews) "Cheap pricing, great location. Everything is at a walking distance BUT it gets way too noisy and you can literally hear someone snoring from 2 rooms away! Would I stay here again? Yes if I’m trying to save money. The room is pretty clean but both times I stayed here both times I found hair on sheets or ground, especially in the shower drain big hair balls. But the staff is nice. Beds are comfy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier Leon $36 nightly $43 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-La-Villa-Hotel.h124818797.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1380000/1374100/1374005/4203b319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/2000000/1380000/1374100/1374005/aa832d20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/2000000/1380000/1374100/1374005/b9d62194.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, iron/ironing board, free cribs/infant beds, travel crib](https://images.trvl-media.com/lodging/2000000/1380000/1374100/1374005/87ebc5c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Ecatepec [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-Fiesta-Inn-Ecatepec.h1374005.Hotel-Information) Ecatepec de Morelos 8.8/10 Excellent (908 reviews) "Room was great service and clean and great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUIS $99 nightly $119 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-Fiesta-Inn-Ecatepec.h1374005.Hotel-Information) ![Standard Double Room | Individually decorated, free WiFi, bed sheets](https://images.trvl-media.com/lodging/72000000/71300000/71298500/71298483/fc231cf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/72000000/71300000/71298500/71298483/668aaad4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/72000000/71300000/71298500/71298483/e9cc1972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71300000/71298500/71298483/dee6f36c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Plaza del Rey | Love Hotel | Solo Adultos [](https://www.expedia.com/Mexico-City-Hotels-Hotel-Villas-Plaza-Del-Rey.h71298483.Hotel-Information) Azcapotzalco 7.6/10 Good (82 reviews) "everything was very good, thanks " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier [](https://www.expedia.com/Mexico-City-Hotels-Hotel-Villas-Plaza-Del-Rey.h71298483.Hotel-Information) ![Sundeck](https://images.trvl-media.com/lodging/58000000/57120000/57116000/57115982/4273bf4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/58000000/57120000/57116000/57115982/75012646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/58000000/57120000/57116000/57115982/0015fef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/58000000/57120000/57116000/57115982/e6a388cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### KALI La Raza Mexico City [](https://www.expedia.com/Mexico-City-Hotels-HOTEL-EL-PATIO-CDMX.h57115982.Hotel-Information) Cuauhtémoc 9.2/10 Wonderful (283 reviews) "todo excelente" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Abraham $56 nightly $67 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-HOTEL-EL-PATIO-CDMX.h57115982.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/89000000/88860000/88853200/88853186/270-9a89d7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/89000000/88860000/88853200/88853186/55f8a60c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/89000000/88860000/88853200/88853186/da906a3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Suite | Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/89000000/88860000/88853200/88853186/224fbc15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Antigua Hotel Boutique [](https://www.expedia.com/Atizapan-De-Zaragoza-Hotels-Antigua-Hotel-Boutique.h88853186.Hotel-Information) Ciudad López Mateos 9.4/10 Exceptional (119 reviews) "Great location and service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jorge Gabriel [](https://www.expedia.com/Atizapan-De-Zaragoza-Hotels-Antigua-Hotel-Boutique.h88853186.Hotel-Information) ![Deluxe Apartment, Balcony, City View | Hypo-allergenic bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/112000000/111590000/111588400/111588388/9130c323_edited_d844.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Senior Apartment | Living area | 50-inch Smart TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/112000000/111590000/111588400/111588388/eef6b71a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Eco-friendly cleaning products](https://images.trvl-media.com/lodging/112000000/111590000/111588400/111588388/2fc0b94b_edited_ee02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Senior Apartment | Living area | 50-inch Smart TV with cable channels, Netflix, streaming services](https://images.trvl-media.com/lodging/112000000/111590000/111588400/111588388/82b5009b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kukun Homero Polanco [](https://www.expedia.com/Mexico-City-Hotels-Casa-Homero-By-Kukun.h111588388.Hotel-Information) Polanco 9.4/10 Exceptional (285 reviews) "Stayed 4 nights on business travel, very accommodating staff and clean apartment/hotel. Will stay again on next business trip." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wing $123 nightly $147 total Mar 31 - Apr 1 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Casa-Homero-By-Kukun.h111588388.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/116000000/115600000/115595000/115594999/697c99fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, bed sheets](https://images.trvl-media.com/lodging/116000000/115600000/115595000/115594999/a0d8d1a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Room | In-room safe, bed sheets](https://images.trvl-media.com/lodging/116000000/115600000/115595000/115594999/0d2ba4bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Double Room | In-room safe, bed sheets](https://images.trvl-media.com/lodging/116000000/115600000/115595000/115594999/3b35ae4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL CASA KAVIA [](https://www.expedia.com/Mexico-City-Hotels-HOTEL-CASA-KAVIA.h115594999.Hotel-Information) Miguel Hidalgo 9.6/10 Exceptional (57 reviews) "Beautiful place. Great location. Friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raul $115 nightly $138 total Mar 24 - Mar 25 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-HOTEL-CASA-KAVIA.h115594999.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/122000000/121040000/121032500/121032447/76e643e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121040000/121032500/121032447/a00d2997.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/122000000/121040000/121032500/121032447/32bb7013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/122000000/121040000/121032500/121032447/0c8171e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hot Elite | Love Hotel | Solo Adultos [](https://www.expedia.com/Mexico-City-Hotels-Hot-Elite.h121032447.Hotel-Information) Miguel Hidalgo 8.0/10 Very Good (14 reviews) "Everything turned out great. We were attended by courteous staff, the room was in perfect shape and with a great view, all in all this was a fantastic stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) alex $39 nightly $47 total Mar 22 - Mar 23 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Hot-Elite.h121032447.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520683/8de05338.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520683/17795064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Premium bedding, in-room safe, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520683/f50c363d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, rainfall showerhead, hair dryer, towels](https://images.trvl-media.com/lodging/10000000/9530000/9520700/9520683/98d81ef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Brasilia [](https://www.expedia.com/Mexico-City-Hotels-Hotel-Brasilia.h9520683.Hotel-Information) Gustavo A. Madero 9.0/10 Wonderful (1,000 reviews) "The room was very clean and spacious, and the staff was very friendly. I would stay there again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) guillermo guerrero $68 nightly $81 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Hotel-Brasilia.h9520683.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/850000/845200/845110/e8a16e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/850000/845200/845110/c74f2fe7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/850000/845200/845110/4ab9df4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/850000/845200/845110/db309597.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Mexico Basilica by IHG [](https://www.expedia.com/Mexico-City-Hotels-Holiday-Inn-Express-Mexico-Basilica.h845110.Hotel-Information) Cuauhtémoc 9.2/10 Wonderful (1,095 reviews) "Awesome hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Luis $68 nightly $81 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Holiday-Inn-Express-Mexico-Basilica.h845110.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/101000000/100960000/100950800/100950771/3d26d1a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100960000/100950800/100950771/5ada5ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business Apartment | 1 bedroom, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/101000000/100960000/100950800/100950771/6e3fa1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100960000/100950800/100950771/8cba4db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moderna, Cómoda Suite Nube en Tepotzotlán centro [](https://www.expedia.com/Tepotzotlan-Hotels-Suite-Nube-Moderna-Comoda-E-Inteligente.h100950771.Hotel-Information) Tepotzotlán 9.8/10 Exceptional (6 reviews) "El lugar es maravilloso" ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Karen Lizeth $54 nightly $65 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Tepotzotlan-Hotels-Suite-Nube-Moderna-Comoda-E-Inteligente.h100950771.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/37000000/37000000/36999700/36999661/ddddd9ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/37000000/37000000/36999700/36999661/dcfde0d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/37000000/37000000/36999700/36999661/6459535a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, towels, soap](https://images.trvl-media.com/lodging/37000000/37000000/36999700/36999661/278f37d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Vía la Villa [](https://www.expedia.com/Mexico-City-Hotels-Capital-O-La-Villa.h36999661.Hotel-Information) Gustavo A. Madero 8.0/10 Very Good (358 reviews) "Good location and good service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) JESUS $42 nightly $51 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Capital-O-La-Villa.h36999661.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/2000000/1900000/1900000/1899952/46b4186a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/2000000/1900000/1900000/1899952/89dae282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds | Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1900000/1900000/1899952/1ee63060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1900000/1900000/1899952/36c10a34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Tepotzotlan [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-City-Express-Tepotzotlan.h1899952.Hotel-Information) Tepotzotlán 8.6/10 Excellent (750 reviews) "Just few yards before the Tepotzotlan toll booth. Great for overnight stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) VICTOR $48 nightly $58 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Tlalnepantla-De-Baz-Hotels-City-Express-Tepotzotlan.h1899952.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/105000000/104380000/104375300/104375221/68a57b5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hot springs](https://images.trvl-media.com/lodging/105000000/104380000/104375300/104375221/40b0c903.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, Balcony, City View | City view](https://images.trvl-media.com/lodging/105000000/104380000/104375300/104375221/9c74448e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment, Balcony, City View | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/105000000/104380000/104375300/104375221/d3740061.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capitalia Antara Polanco [](https://www.expedia.com/Mexico-City-Hotels-Capitalia-Luxury-Apartments-E-Allan-Poe.h104375221.Hotel-Information) Polanco 9.2/10 Wonderful (243 reviews) "Amazing stay and perfect location" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) mehul $168 nightly $204 total Mar 27 - Mar 28 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Capitalia-Luxury-Apartments-E-Allan-Poe.h104375221.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/898400/898306/de024fd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/900000/898400/898306/d85e4810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/1000000/900000/898400/898306/e1106320.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/900000/898400/898306/8290f8b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Real Inn Perinorte [](https://www.expedia.com/Mexico-City-Hotels-Real-Inn-Perinorte.h898306.Hotel-Information) Tlalnepantla de Baz 8.6/10 Excellent (1,002 reviews) "Excelente " ![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg) Ruben $69 nightly $83 total Mar 25 - Mar 26 Total with taxes and fees [](https://www.expedia.com/Mexico-City-Hotels-Real-Inn-Perinorte.h898306.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-04&endDate=2026-04-05®ionId=553248635975856606&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635975856606.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635975856606.Travel-Guide-Hotels) ## Top Santa Cruz Hotel Reviews ![InterContinental Presidente Mexico City by IHG](https://images.trvl-media.com/lodging/1000000/10000/4700/4641/dfbbea61_y.jpg) ### InterContinental Presidente Mexico City by IHG 10/10 Excellent "Great stay" [](https://expedia.com/Mexico-City-Hotels-InterContinental-Presidente-Mexico-City.h4641.Hotel-Information) ![Hotel Parque Satelite](https://images.trvl-media.com/lodging/13000000/12240000/12238300/12238224/cbc9925a_y.jpg) ### Hotel Parque Satelite 10/10 Excellent "Excelente Hotel, amplio, a pesar de su edad esta bien conservado , personal atento y pocos metros de Mundo E" [](https://expedia.com/Mexico-City-Hotels-Hotel-Parque-Satelite.h12238224.Hotel-Information) ![Casa Olea](https://images.trvl-media.com/lodging/111000000/110410000/110402700/110402645/1d226d9c_y.jpg) ### Casa Olea 10/10 Excellent "Clean room, friendly staff, safe area" [](https://expedia.com/Mexico-City-Hotels-Casa-Olea.h110402645.Hotel-Information) ![UTOPIC Polanco by ULIV](https://images.trvl-media.com/lodging/92000000/91040000/91031300/91031272/32adb770_y.jpg) ### UTOPIC Polanco by ULIV 10/10 Excellent "Very business friendly, close to everything" [](https://expedia.com/Mexico-City-Hotels-Utopic-Polanco-By-Uliv.h91031272.Hotel-Information) ![St Isidro Suites Corporate Housing SPA & Wellness Center](https://images.trvl-media.com/lodging/2000000/1890000/1887800/1887706/e16e8c16_y.jpg) ### St Isidro Suites Corporate Housing SPA & Wellness Center 10/10 Excellent "Hotel staff was extremely helpful. Property is clean. Beds are comfortable!" [](https://expedia.com/Mexico-City-Hotels-St-Isidro-Corporate-Housing.h1887706.Hotel-Information) ![Hyatt Regency Mexico City](https://images.trvl-media.com/lodging/1000000/30000/23400/23360/d2b1584f_y.jpg) ### Hyatt Regency Mexico City 10/10 Excellent "Excellent location, nice clean rooms. Staff very friendly " [](https://expedia.com/Mexico-City-Hotels-Hyatt-Regency-Mexico-City.h23360.Hotel-Information) ![JW Marriott Hotel Mexico City Polanco](https://images.trvl-media.com/lodging/1000000/50000/42100/42008/w4000h2663x0y0-4b7c45be_y.jpg) ### JW Marriott Hotel Mexico City Polanco 10/10 Excellent "Great location and friendly staff! " [](https://expedia.com/Mexico-City-Hotels-JW-Marriott-Hotel-Mexico-City.h42008.Hotel-Information) ![Holiday Inn Express Mexico Basilica by IHG](https://images.trvl-media.com/lodging/1000000/850000/845200/845110/e8a16e8e_y.jpg) ### Holiday Inn Express Mexico Basilica by IHG 8/10 Good "No airport shuttle available at hotel " [](https://expedia.com/Mexico-City-Hotels-Holiday-Inn-Express-Mexico-Basilica.h845110.Hotel-Information) ![Krystal Satélite María Bárbara](https://images.trvl-media.com/lodging/9000000/8060000/8054100/8054040/8e7663eb_y.jpg) ### Krystal Satélite María Bárbara 10/10 Excellent "Room was perfect food was great next to mundo E" [](https://expedia.com/Mexico-City-Hotels-Krystal-Satelite-Maria-Barbara.h8054040.Hotel-Information) ## More cheap stays in Santa Cruz ![Hotel Ancona - Adults Only](https://images.trvl-media.com/lodging/24000000/23610000/23606400/23606397/c49d1ea6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Ancona - Adults Only 226 Calle Eligio Ancona Mexico City CDMX $16 nightly $20 total Mar 29 - Mar 30 Total with taxes and fees 8.2/10 Very Good! (374 reviews) [](https://expedia.com/Mexico-City-Hotels-Hotel-Ancona-Adults-Only.h23606397.Hotel-Information) ![Hotel SR92 Only Adults](https://images.trvl-media.com/lodging/45000000/44560000/44550600/44550598/6599922d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel SR92 Only Adults Calle de Francisco Díaz Covarrubias 92 Mexico City CDMX $30 nightly $35 total Mar 22 - Mar 23 Total with taxes and fees 7.2/10 Good! (302 reviews) [](https://expedia.com/Mexico-City-Hotels-Hotel-SR92.h44550598.Hotel-Information) ![Downtown Treasure Place](https://images.trvl-media.com/lodging/84000000/83930000/83928400/83928395/646fe411_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Downtown Treasure Place 85 Marte Guerrero Mexico City CDMX $36 nightly $43 total Mar 22 - Mar 23 Total with taxes and fees 8.8/10 Excellent! (790 reviews) [](https://expedia.com/Mexico-City-Hotels-DOWNTOW-TREASURE-PLACE.h83928395.Hotel-Information) ![Casa Olea](https://images.trvl-media.com/lodging/111000000/110410000/110402700/110402645/1d226d9c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Casa Olea C. de Francisco Díaz Covarrubias Mexico City CDMX $56 nightly $66 total Mar 23 - Mar 24 Total with taxes and fees 9.4/10 Exceptional! (727 reviews) [](https://expedia.com/Mexico-City-Hotels-Casa-Olea.h110402645.Hotel-Information) ![KALI La Raza Mexico City](https://images.trvl-media.com/lodging/58000000/57120000/57116000/57115982/4273bf4b_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### KALI La Raza Mexico City AV. INSURGENTES NORTE 734 Mexico City CDMX $56 nightly $67 total Mar 22 - Mar 23 Total with taxes and fees 9.2/10 Wonderful! (283 reviews) [](https://expedia.com/Mexico-City-Hotels-HOTEL-EL-PATIO-CDMX.h57115982.Hotel-Information) ![HOTEL CASA KAVIA](https://images.trvl-media.com/lodging/116000000/115600000/115595000/115594999/697c99fb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL CASA KAVIA AVENIDA PRADO NORTE Mexico City MEX $115 nightly $138 total Mar 24 - Mar 25 Total with taxes and fees 9.6/10 Exceptional! (57 reviews) [](https://expedia.com/Mexico-City-Hotels-HOTEL-CASA-KAVIA.h115594999.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa Cruz? > This area is the heart of Santa Cruz, characterized by its historic architecture, cobblestone streets, and a relaxed pace. The Jardín Principal is a central gathering spot, surrounded by the main cathedral, government palace, and many shops and eateries. It's very walkable and offers a genuine sense of the city's heritage. > > > Couples looking for a romantic and culturally rich experience will find the city center ideal. They can enjoy leisurely strolls through historic streets, dine at charming restaurants with outdoor seating, and visit local artisan shops. The evening brings a pleasant ambiance as locals and visitors gather in the Jardín Principal. > > > For solo travelers, the city center is also an excellent choice. It provides easy access to local markets, museums, and public transportation, making it convenient to explore independently. ### When is the best time to go to Santa Cruz? > During these months, you can expect sunny skies, comfortable temperatures ranging from 70°F to 85°F (21°C to 29°C), and very little rainfall. This makes it ideal for enjoying outdoor activities like exploring the local markets, visiting historical sites, or relaxing at nearby natural attractions. > > > Couples often find these months great for a romantic getaway, as the pleasant weather allows for leisurely strolls through town and comfortable dining experiences at outdoor cafes. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Cruz hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Santa Cruz hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - More ways to book - [Hotels near Hacienda La Concepcion ](https://www.expedia.com/Hacienda-La-Concepcion-Hotels.0-l705862077297070080-0.Travel-Guide-Filter-Hotels) - [Hotels near Temple of San Francisco Javier ](https://www.expedia.com/Temple-Of-San-Francisco-Javier-Hotels.0-l553248621556237640-0.Travel-Guide-Filter-Hotels) - [Hotels near National Museum of the Viceroyalty ](https://www.expedia.com/National-Museum-Of-The-Viceroyalty-Hotels.0-l553248621532977207-0.Travel-Guide-Filter-Hotels) - [Hotels near San Martin ](https://www.expedia.com/San-Martin-Tepotzotlan-Hotels.0-n553248635976400156-0.Travel-Guide-Filter-Hotels) - [Cuautitlan Izcalli Hotels ](https://www.expedia.com/Cuautitlan-Izcalli-Hotels.d179275.Travel-Guide-Hotels) - [Tepotzotlán Hotels ](https://www.expedia.com/Tepotzotlan-Hotels.d6084307.Travel-Guide-Hotels) - 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