Find hotels in Santa Cruz from $19

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
Jun 5 - Jun 7
In two weeks
Jun 12 - Jun 14

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Outdoor treatment areas, sauna, body treatments, aromatherapy

La Morada Tepotzotlan Boutique & Spa

La Morada Tepotzotlan Boutique & Spa
3.5 star property
Tepotzotlán
7.6 out of 10, Good, (43 reviews)
"na"
Mexico
Karina Ponce
$234 nightly
The price is $285
Jun 1 - Jun 2
Total with taxes and fees
La Morada Tepotzotlan Boutique & Spa
Building design

Hotel Finca Las Hortensias

Hotel Finca Las Hortensias
3.0 star property
Tepotzotlán
8.4 out of 10, Very Good, (193 reviews)
"Nice rooms and grounds."
United States
Raymond
$55 nightly
The price is $68
Jun 1 - Jun 2
Total with taxes and fees
Hotel Finca Las Hortensias
Interior

Hotel Único La Villa

Hotel Único La Villa
2.0 star property
Gustavo A. Madero
7.6 out of 10, Good, (69 reviews)
"Hotel was clean. There was no hot water for the 2 nights of my stay & no communication was received from the staff regarding any repairs."
United States
Paul
$37 nightly
The price is $45
Jun 1 - Jun 2
Total with taxes and fees
Hotel Único La Villa
Exterior

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
3.5 star property
Zumpango
9.4 out of 10, Exceptional, (1,162 reviews)
"Very clean hotel and friendly staff."
United States
Pedro
$140 nightly
The price is $168
Jul 1 - Jul 2
Total with taxes and fees
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG
Exterior

Antigua Hotel Boutique

Antigua Hotel Boutique
3.5 star property
Ciudad López Mateos
9.4 out of 10, Exceptional, (138 reviews)
"Hotel was very nice and clean. Staff were very friendly. We really enjoyed our stay!"
United States
George
$67 nightly
The price is $81
Jun 7 - Jun 8
Total with taxes and fees
Antigua Hotel Boutique
Restaurant

Verticca Hotel

Verticca Hotel
3.0 star property
Ojo de Agua
9.2 out of 10, Wonderful, (288 reviews)
"Good stay prior to a trip"
United States
SONIA
$140 nightly
The price is $168
Jun 1 - Jun 2
Total with taxes and fees
Verticca Hotel
Indoor pool

Fiesta Inn Ecatepec

Fiesta Inn Ecatepec
3.5 star property
Ecatepec de Morelos
8.8 out of 10, Excellent, (952 reviews)
"Good place to stay"
Canada
Josue
$94 nightly
The price is $113
Jun 5 - Jun 6
Total with taxes and fees
Fiesta Inn Ecatepec
Lobby

City Express by Marriott Ciudad de México La Villa

City Express by Marriott Ciudad de México La Villa
4.0 star property
Gustavo A. Madero
8.8 out of 10, Excellent, (1,002 reviews)
"The hotel was cleaned and looked recently remodeled. Enjoyed our stay."
United States
Roger
$69 nightly
The price is $83
Jun 8 - Jun 9
Total with taxes and fees
City Express by Marriott Ciudad de México La Villa
Bar (on property)

Hot Elite | Love Hotel | Solo Adultos

Hot Elite | Love Hotel | Solo Adultos
3.0 star property
Miguel Hidalgo
8.4 out of 10, Very Good, (20 reviews)
"The rooms were extremely clean! The price and location was great. "
United States
Johanna
$51 nightly
The price is $61
Jun 1 - Jun 2
Total with taxes and fees
Hot Elite | Love Hotel | Solo Adultos
Exterior

HOTEL CASA KAVIA

HOTEL CASA KAVIA
2.0 star property
Miguel Hidalgo
9.4 out of 10, Exceptional, (110 reviews)
"Excelente hotel "
Mexico
Miguel
$118 nightly
The price is $142
Jun 1 - Jun 2
Total with taxes and fees
HOTEL CASA KAVIA
Terrace/patio

Hotel Brasilia

Hotel Brasilia
3.0 star property
Gustavo A. Madero
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice staff, clean and great to go to sleep"
United States
Antonia
$53 nightly
The price is $65
Jun 13 - Jun 14
Total with taxes and fees
Hotel Brasilia
Terrace/patio

District Polanco by Lumina

District Polanco by Lumina
2.0 star property
Polanco
9.4 out of 10, Exceptional, (185 reviews)
"excellent close to everything i restaurant coffee shops and bars!!!"
United States
Nelly
$133 nightly
The price is $159
Jun 4 - Jun 5
Total with taxes and fees
District Polanco by Lumina
Interior

Hotel Vía la Villa

Hotel Vía la Villa
2.5 star property
Gustavo A. Madero
8.0 out of 10, Very Good, (369 reviews)
"Hot tub hot but a lot of hair in it. Plenty of shops and restaurants near by. Decent place to stay. "
United States
Alexis
$54 nightly
The price is $64
Jun 20 - Jun 21
Total with taxes and fees
Hotel Vía la Villa
Restaurant

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG
3.0 star property
Cuauhtémoc
9.4 out of 10, Exceptional, (1,137 reviews)
"Loved breakfast!"
United States
Elizabeth
$80 nightly
The price is $96
Jun 5 - Jun 6
Total with taxes and fees
Holiday Inn Express Mexico Basilica by IHG
Restaurant

Fiesta Inn Express Perinorte

Fiesta Inn Express Perinorte
3.5 star property
Tultitlan
9.0 out of 10, Wonderful, (513 reviews)
"Lovely hotel. Breakfast was great but no full restaurant in the hotel or near the hotel. "
United States
Rodger
$91 nightly
The price is $109
Jun 3 - Jun 4
Total with taxes and fees
Fiesta Inn Express Perinorte
Property amenity

Fairfield Inn & Suites Mexico City Vallejo

Fairfield Inn & Suites Mexico City Vallejo
3.0 star property
Azcapotzalco
9.2 out of 10, Wonderful, (1,004 reviews)
"Perfect location and staff "
United States
Laureen
$95 nightly
The price is $114
Jun 5 - Jun 6
Total with taxes and fees
Fairfield Inn & Suites Mexico City Vallejo
Standard Double Room | Individually decorated, free WiFi, bed sheets

Hot Plaza del Rey | Love Hotel | Solo Adultos

Hot Plaza del Rey | Love Hotel | Solo Adultos
2.5 star property
Azcapotzalco
7.6 out of 10, Good, (92 reviews)
"everything was very good, thanks "
United States
Javier
$49 nightly
The price is $59
Jun 7 - Jun 8
Total with taxes and fees
Hot Plaza del Rey | Love Hotel | Solo Adultos
Sundeck

KALI La Raza Mexico City

KALI La Raza Mexico City
2.5 star property
Cuauhtémoc
9.2 out of 10, Wonderful, (324 reviews)
"Close to the shrine of Our Lady of Guadalupe, clean rooms, great breakfast and friendly staff"
United States
Pamela
$73 nightly
The price is $88
Jun 15 - Jun 16
Total with taxes and fees
KALI La Raza Mexico City
Front of property

Real Inn Perinorte

Real Inn Perinorte
4.0 star property
Tlalnepantla de Baz
8.6 out of 10, Excellent, (1,006 reviews)
"Very convenient location"
United States
Antonio
$56 nightly
The price is $67
Jun 7 - Jun 8
Total with taxes and fees
Real Inn Perinorte
Bar (on property)

Courtyard Mexico City Vallejo

Courtyard Mexico City Vallejo
3.5 star property
Azcapotzalco
8.8 out of 10, Excellent, (653 reviews)
"Clean hotel with comfortable beds. Staff was very friendly!"
United States
David
$95 nightly
The price is $114
Jun 5 - Jun 6
Total with taxes and fees
Courtyard Mexico City Vallejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

10/10 Excellent
"The place is good, specially 1st timer in Mexico City. Enjoyed our stay in the hotel, clean, good staff and good breakfast. The only thing, if you're sensitive to noise, you can hear the car passing through and will wake you up."
JACQUELINE 2-night trip
Posted 4 hours ago
Holiday Inn Express Mexico Basilica by IHG

More cheap stays in Santa Cruz

Hotel Ancona - Adults Only

Hotel Ancona - Adults Only

226 Calle Eligio Ancona Mexico City CDMX
$16 nightly
The price is $19 total per night from Jul 1 to Jul 2
$19 total
Jul 1 - Jul 2
Total with taxes and fees
8.2/10 Very Good! (388 reviews)

Why book with Expedia?

  • Flexible booking

    On Expedia, you can find plenty of hotels with flexible cancellation in Santa Cruz using the “Fully refundable property” search filter. Just be sure to always double-check each hotel's cancellation policy before booking.

  • Book now and pay later

    With countless book now, pay later options, there's no need to wait till payday to grab a deal. Use the “Reserve now, pay later” search filter to view all properties available with this payment option in Santa Cruz.

  • Hotel comparison

    Thanks to the handy “Compare properties” tool on Expedia, you can compare hotels in Santa Cruz side by side with just a few clicks.

  • Member prices

    Join Expedia's loyalty program, One Key, for free and unlock Member Prices and rewards on select hotels worldwide. Simply log in when you search and look out for the blue savings label.

Frequently asked questions

What is the best area to stay in Santa Cruz?
The best area to stay in Santa Cruz is the city center, particularly around the main square, Jardín Principal.

This area is the heart of Santa Cruz, characterized by its historic architecture, cobblestone streets, and a relaxed pace. The Jardín Principal is a central gathering spot, surrounded by the main cathedral, government palace, and many shops and eateries. It's very walkable and offers a genuine sense of the city's heritage.

Couples looking for a romantic and culturally rich experience will find the city center ideal. They can enjoy leisurely strolls through historic streets, dine at charming restaurants with outdoor seating, and visit local artisan shops. The evening brings a pleasant ambiance as locals and visitors gather in the Jardín Principal.

For solo travelers, the city center is also an excellent choice. It provides easy access to local markets, museums, and public transportation, making it convenient to explore independently.
When is the best time to go to Santa Cruz?
The best time to visit Santa Cruz, State of Mexico, is during the dry season, from November to April, for optimal weather conditions.

During these months, you can expect sunny skies, comfortable temperatures ranging from 70°F to 85°F (21°C to 29°C), and very little rainfall. This makes it ideal for enjoying outdoor activities like exploring the local markets, visiting historical sites, or relaxing at nearby natural attractions.

Couples often find these months great for a romantic getaway, as the pleasant weather allows for leisurely strolls through town and comfortable dining experiences at outdoor cafes.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How can I save on a Santa Cruz hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Cruz hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $19 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia