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Santa Cruz Vacation Rentals

Check prices for these dates

In two weeks
Nov 13 - Nov 15
In two months
Dec 25 - Dec 27
In three months
Jan 22 - Jan 24
In four months
Feb 19 - Feb 21

Our top choices for Santa Cruz vacation rentals

A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

1. A30 Plaza Acequia Suite Black Plus

A30 Plaza Acequia Suite Black Plus
4.0 star property
Cuautitlán Izcalli
10.0 out of 10, Exceptional, (1 review)
"Todo un ambiente acogedor"
Mexico
GENER KEINER
$81 nightly
The price is $97
Oct 28 - Oct 29
Total with taxes and fees
A30 Plaza Acequia Suite Black Plus
Balcony

2. S09 PREMIUM SUITE Full Service WiFi

S09 PREMIUM SUITE Full Service WiFi
4.0 star property
Ciudad López Mateos
9.6 out of 10, Exceptional, (4 reviews)
"Excelente"
United States
Yulissa Rubi
$68 nightly
The price is $82
Nov 3 - Nov 4
Total with taxes and fees
S09 PREMIUM SUITE Full Service WiFi
Living area

3. Lofts by Verticca San Francisco

Lofts by Verticca San Francisco
3.5 star property
Ojo de Agua
8.6 out of 10, Excellent, (46 reviews)
"Great staff, clean environment, rooms look and feel new, how ever the lack of AC and heating, the blinds only covered half of the window letting the day light in even if you didn’t needed, the hot water was extremely hot and impossible to regulate, the price is a bit high but not outrageous. Overall I will book them again!"
United States
Gerardo Gonzalez
$51 nightly
The price is $62
Nov 27 - Nov 28
Total with taxes and fees
Lofts by Verticca San Francisco
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

4. A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA

A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (8 reviews)
"Buena la estancia "
Mexico
Héctor
$72 nightly
The price is $86
Oct 29 - Oct 30
Total with taxes and fees
A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

5. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
8.0 out of 10, Very good, (4 reviews)
"No dejan dormir pasaron algunos huéspedes ablandó fuerte y caminando por los corredores y nadie les llamó la atención. Según parecía estaban borrachos"
United States
Mario
$72 nightly
The price is $86
Nov 4 - Nov 5
Total with taxes and fees
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

6. A25 Full Suite MiniDept at Plaza Acequia

A25 Full Suite MiniDept at Plaza Acequia
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
$83 nightly
The price is $100
Nov 24 - Nov 25
Total with taxes and fees
A25 Full Suite MiniDept at Plaza Acequia
A compact kitchen with a built-in microwave, a gas stove, and a dishwasher.

7. Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (3 reviews)
"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."
United States
Nathan
$63 nightly
The price is $75
Nov 10 - Nov 11
Total with taxes and fees
Moderna, Comoda Suite Palma en Tepotzotlán centro
Interior entrance

8. Moderna, Cómoda Suite Nube en Tepotzotlán centro

Moderna, Cómoda Suite Nube en Tepotzotlán centro
4.0 star property
Tepotzotlán
9.6 out of 10, Exceptional, (9 reviews)
"Increíble!! Una habitación pequeña pero perfecta, muy cómoda, muy linda, daban ganas de quedarse más tiempo! Muy recomendable. Vale totalmente la pena"
Mexico
Eduardo
$52 nightly
The price is $63
Nov 16 - Nov 17
Total with taxes and fees
Moderna, Cómoda Suite Nube en Tepotzotlán centro
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

9. A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Lo único que me disgusta es que no hay agua caliente )): Pero sin duda iré todos los 12 de cada mes "
Mexico
Jeik
$72 nightly
The price is $87
Nov 21 - Nov 22
Total with taxes and fees
A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

10. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

A07 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Buen lugar tranquilo "
Mexico
Valeria
$52 nightly
The price is $62
Nov 25 - Nov 26
Total with taxes and fees
A07 SUPER CITY SUITES AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

11. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (3 reviews)
"Buenas instalaciones y ubicación para mis desplazamientos"
Mexico
ANGEL
$72 nightly
The price is $86
Nov 2 - Nov 3
Total with taxes and fees
A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A modern living room with a sofa, a glass coffee table, a dining table with chairs, a painting on the wall, and a ceiling light.

12. Lofts by Verticca Héroes

Lofts by Verticca Héroes
2.0 star property
Ojo de Agua
10.0 out of 10, Exceptional, (1 review)
$62 nightly
The price is $74
Oct 28 - Oct 29
Total with taxes and fees
Lofts by Verticca Héroes
A palm tree in front of a building with arched windows and a brick facade.

13. cabañas en arcos del sitio

cabañas en arcos del sitio
3.0 star property
Nicolás Romero
$145 nightly
The price is $174
Nov 1 - Nov 2
Total with taxes and fees
cabañas en arcos del sitio
A balcony with two chairs, a small table with a book and a cup, and a view of the cityscape.

14. S06 PREMIUM SUITE Full Service WiFi Kitc

S06 PREMIUM SUITE Full Service WiFi Kitc
4.0 star property
Ciudad López Mateos
9.8 out of 10, Exceptional, (6 reviews)
"Estuvo super bien nuestra estancia "
Mexico
Sophie
$68 nightly
The price is $82
Nov 5 - Nov 6
Total with taxes and fees
S06 PREMIUM SUITE Full Service WiFi Kitc
A compact kitchen with a wooden cabinet, a sink, and a countertop. There are kitchen utensils and a coffee maker on the counter.

15. S02 FULL SUITE ITESM CEM WiFi Terraza

S02 FULL SUITE ITESM CEM WiFi Terraza
4.0 star property
Ciudad López Mateos
10.0 out of 10, Exceptional, (1 review)
"Muy limpio Agradable la señorita de limpieza"
Mexico
Mauricio
$56 nightly
The price is $68
Nov 1 - Nov 2
Total with taxes and fees
S02 FULL SUITE ITESM CEM WiFi Terraza
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

16. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
$66 nightly
The price is $79
Nov 25 - Nov 26
Total with taxes and fees
A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious indoor area with a high ceiling, metal beams, and a staircase. There are multiple seating areas with tables and chairs, and a variety of plants are visible.

17. Downtown Treasure Place

Downtown Treasure Place
2.5 star property
Cuauhtémoc
8.8 out of 10, Excellent, (924 reviews)
"staff was really nice and bathrooms really clean"
United States
Rishi
$29 nightly
The price is $35
Oct 28 - Oct 29
Total with taxes and fees
Downtown Treasure Place
A modern bedroom with a large bed, a nightstand, a desk, and a view through large windows.

18. S10 PREMIUM SUITE Full Service WiFi

S10 PREMIUM SUITE Full Service WiFi
4.0 star property
Ciudad López Mateos
8.0 out of 10, Very good, (1 review)
"Habitacion limpia"
Mexico
Yolanda Sandoval
$68 nightly
The price is $82
Nov 5 - Nov 6
Total with taxes and fees
S10 PREMIUM SUITE Full Service WiFi
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

19. A13 SUPER CITY SUITE PLAZA ACEQUIA

A13 SUPER CITY SUITE PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
"Buen servicio "
Mexico
Ruben
$71 nightly
The price is $86
Nov 24 - Nov 25
Total with taxes and fees
A13 SUPER CITY SUITE PLAZA ACEQUIA
A rooftop terrace with a fire feature, seating, and a city view at dusk.

20. ULIV Polanco

ULIV Polanco
4.0 star property
Miguel Hidalgo
8.8 out of 10, Excellent, (504 reviews)
"Great place to stay!"
United States
Maria
$159 nightly
The price is $190
Nov 21 - Nov 22
Total with taxes and fees
ULIV Polanco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Hotel MX forum buenavista CDMX, Trademark by Wyndham

Hotel MX forum buenavista CDMX, Trademark by Wyndham

10/10 Excellent
"Diana es súper amable y resuelve problemas muy profesionalmente. Definitivamente regresaré"
Elvis 3-night trip
Posted 2 hours ago
Hotel MX forum buenavista CDMX, Trademark by Wyndham

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $35 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxe Polanco Home Private Yard and Private Patio: This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Parque Acuatico Vito Spa, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.