Santa Cruz Vacation Rentals from $43: Search Short-Term Rentals

Q: What's the top vacation rental in Santa Cruz?

Luxe Polanco Home Private Yard and Private Patio : This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

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Our top choices for Santa Cruz vacation rentals

1. Moderna, Cómoda Suite Nube en Tepotzotlán centro

Tepotzotlán

Eduardo

$58 nightly

Sep 11 - Sep 12

Total with taxes and fees

2. Moderna, Comoda Suite Palma en Tepotzotlán centro

Tepotzotlán

"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."

Nathan

$69 nightly

Sep 14 - Sep 15

Total with taxes and fees

3. A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA

Cuautitlan Izcalli

Héctor

$79 nightly

Sep 12 - Sep 13

Total with taxes and fees

4. A30 Plaza Acequia Suite Black Plus

Cuautitlán Izcalli

GENER KEINER

$90 nightly

Sep 15 - Sep 16

Total with taxes and fees

5. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

Cuautitlan Izcalli

Caleb

$79 nightly

Oct 9 - Oct 10

Total with taxes and fees

6. A27 Full Suite MiniDept at Plaza Acequia

Cuautitlan Izcalli

Mario Alberto

$75 nightly

Sep 11 - Sep 12

Total with taxes and fees

7. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

Cuautitlan Izcalli

ANGEL

$79 nightly

Sep 14 - Sep 15

Total with taxes and fees

8. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

Cuautitlan Izcalli

Valeria

$57 nightly

Oct 9 - Oct 10

Total with taxes and fees

9. A23 Full Suite MiniDept at Plaza Acequia

Cuautitlan Izcalli

$75 nightly

Sep 16 - Sep 17

Total with taxes and fees

10. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

Cuautitlan Izcalli

$73 nightly

Oct 9 - Oct 10

Total with taxes and fees

11. A25 Full Suite MiniDept at Plaza Acequia

Cuautitlan Izcalli

$92 nightly

Oct 10 - Oct 11

Total with taxes and fees

Family Studio Suite, Balcony, City View | Private kitchen

12. S02 FULL SUITE ITESM CEM WiFi Terraza

Ciudad López Mateos

Mauricio

$78 nightly

Sep 11 - Sep 12

Total with taxes and fees

13. A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

Cuautitlan Izcalli

$74 nightly

Sep 12 - Sep 13

Total with taxes and fees

14. A13 SUPER CITY SUITE PLAZA ACEQUIA

Cuautitlan Izcalli

Ruben

$79 nightly

Oct 9 - Oct 10

Total with taxes and fees

15. A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

Cuautitlan Izcalli

Jorge

$79 nightly

Oct 9 - Oct 10

Total with taxes and fees

16. cabañas en arcos del sitio

Nicolás Romero

$160 nightly

Sep 11 - Sep 12

Total with taxes and fees

17. A15 Full Suite MiniDept at Plaza Acequia

Cuautitlan Izcalli

$97 nightly

Oct 1 - Oct 2

Total with taxes and fees

18. A28 SUPER FULL SUITE AT PLAZA ACEQUIA

Cuautitlan Izcalli

Dayra

$78 nightly

Sep 11 - Sep 12

Total with taxes and fees

19. S06 PREMIUM SUITE Full Service WiFi Kitc

Ciudad López Mateos

Sophie

$75 nightly

Sep 11 - Sep 12

Total with taxes and fees

Executive Studio Suite, 1 King Bed, Balcony, City View | Balcony

20. S07 PREMIUM SUITE Full Service WiFi STV

Ciudad López Mateos

"En general la habitación excelente y el personal en el inmueble muy amable, un punto que destaco, es que cuenta con todos los servicios y para mi que hice home office, no tuve ningún problema con el internet, algo que quizás pueda mejorar, es que, en estancias semanales ofrecer un servicio completo de limpieza de la habitación es muy poco, ofrecer 2 servicios completos de limpieza sería estupendo"

Alan Gilberto

$75 nightly

Sep 11 - Sep 12

Total with taxes and fees

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Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

10/10 Excellent

"Good"

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

10/10 Excellent

"This new airport is in an area with not a lot around except the airport, so it is good that they have a restaurant and vending machine for after hours. You can walk to the airport via a pedestrian bridge or the hotel shuttle will whisk you to the main door."

Collections by ULIV Polanco

10/10 Excellent

"This is honestly the best place I have stayed at in Mexico City. The location is premium and near to everything you want to see but what makes this place HIGHLY EXCEPTIONAL is the high level of service and attention you will receive from the staff. They are trully dedicated to making your experience amazing. Its an excellent place and again... Staff is just extraordinary, going above and beyond and giving the extra mile to provide you with an enjoyable stay."

Las Suites Campos Eliseos

10/10 Excellent

"Our family of four stayed here for a week, and we had a truly wonderful experience. We were able to check in early at 1 p.m., which was such a considerate gesture. The unit was spacious, clean, and well maintained. Having two bedrooms and two bathrooms was absolutely amazing for a family of four, especially with a teenager! We also really enjoyed the breakfast, and the refreshment station in the lobby was a lovely touch. The staff were fantastic throughout our stay. A special shout-out to Daniel, the concierge, who was incredibly attentive, courteous, and helpful. America at breakfast was also wonderful and made our mornings even more enjoyable. The location felt very safe and convenient, which gave us great peace of mind while traveling as a family. Overall, we had an excellent stay and would happily return. Highly recommended for families!"

Find out more about Santa Cruz

Everything you need to know about Santa Cruz vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Cruz vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Cruz in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $43 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Cruz?

Yes, you can find vacation rentals near popular points of interest in Santa Cruz, or you can go with a secluded option if you want a relaxing place to stay.

What's the top vacation rental in Santa Cruz?

Luxe Polanco Home Private Yard and Private Patio: This vacation home rental near Santa Cruz offers a garden, a selection of games, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Perimagico, or get out into nature at a spot like Hacienda La Concepcion. San Marcos Power Center and Xochitla Ecological Park are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa Cruz like?

Vacation rentals are private properties you can book for a long or short time in Santa Cruz. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for family trips.

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Check prices for these dates

Our top choices for Santa Cruz vacation rentals

1. Moderna, Cómoda Suite Nube en Tepotzotlán centro

2. Moderna, Comoda Suite Palma en Tepotzotlán centro

3. A14 SUPER PREMIUM SUITE AT PLAZA ACEQUIA

4. A30 Plaza Acequia Suite Black Plus

5. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

6. A27 Full Suite MiniDept at Plaza Acequia

7. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

8. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

9. A23 Full Suite MiniDept at Plaza Acequia

10. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

11. A25 Full Suite MiniDept at Plaza Acequia

12. S02 FULL SUITE ITESM CEM WiFi Terraza

13. A24 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

14. A13 SUPER CITY SUITE PLAZA ACEQUIA

15. A10 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

16. cabañas en arcos del sitio

17. A15 Full Suite MiniDept at Plaza Acequia

18. A28 SUPER FULL SUITE AT PLAZA ACEQUIA

19. S06 PREMIUM SUITE Full Service WiFi Kitc

20. S07 PREMIUM SUITE Full Service WiFi STV

Find vacation rentals that suit your style

Top Santa Cruz Hotel Reviews

Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Hotel & Villas Panamá

Hyatt Regency Mexico City

Collections by ULIV Polanco

Kukun Homero Polanco

Casa Olea

Las Suites Campos Eliseos

Krystal Satélite María Bárbara

Find out more about Santa Cruz

Frequently asked questions

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