Santa Cruz Vacations from $952
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The Latest Santa Cruz vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,059
per person
Nov 5 - Nov 10
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco.
The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.
Reviewed on Sep 2, 2026
Megapolis Hotel Panamá
San Francisco
$1,148
per person
Oct 6 - Oct 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,671 reviews)
Our stay was very comfortable at the Megapolis. We were 2 adults and 2 children in a deluxe room with 2 beds. There was a mini fridge with refreshments and snacks upon arrival and water was replenished everyday.. The buffet breakfast selection was vast and the sky walk connecting to the mall was very convenient but there were stairs so going with a stroller was difficult. The hotel decor was very impressive however some of the furniture appeared to be in disrepair and the hallway carpets on our floor needed to be vacuumed as there was visible dirt, even right outside our door, for the duration of our stay.
Overall I would definitely stay here again.
Reviewed on Sep 1, 2026
Santa Cruz Hotel Deals
Bocas del Mar Hotel
Road to Boca Chica Boca Chica Chiriqui
$196 nightly
$218 total
Oct 2 - Oct 3
Total with taxes and fees
9.6/10 Exceptional! (237 reviews)
"This was a 10 out of 10. Everyone was so helpful, we were treated like royalty. The room was clean and modern. The pool was brilliant, the food exceptional,the drinks were delicious and the beer was cold. I could not ask for more. Our stay was wonderful!"
Reviewed on Aug 31, 2026
Las Lajas Beach Resort
Playa Las Lajas Las Lajas Chiriqui
9.2/10 Wonderful! (138 reviews)
"Great place for a beach stay in Panama. We loved the resort,the staff,the beach. Keep in mind this is a more rustic area,but the value here is terrific. We really enjoyed it. Also food and drinks are very reasonably priced,and very good."
Reviewed on Mar 26, 2025
Seagull Cove Resort
Calle Principal Boca Chica Chiriqui
$162 nightly
$178 total
Oct 2 - Oct 3
Total with taxes and fees
9.6/10 Exceptional! (101 reviews)
"Beautiful property that is surrounded by the jungle. The cove is gorgeous and we heard monkeys, saw roads and tree frogs and so many different types of birds. Dinner and breakfast were great and there was something for everyone in my family."
Reviewed on Jul 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
