Santa Cruz Vacations from $637
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The Latest Santa Cruz vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
Save 100% on your flight
Price was $1,805, price is now $1,223 per person
$1,223
per person
Mar 25 - Mar 30
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,002 reviews)
Location, amenities and staff were great.
Reviewed on Feb 3, 2026
Villa Botero By Casa Mojito B&B
Price was $1,147, price is now $812 per person
$812
per person
Mar 11 - Mar 16
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
We stayed one night and it exceeded our expectations. The owners were incredibly friendly and easy to contact, making us feel right at home. Everything was spotless, and the atmosphere was warm and inviting. The homemade breakfast was a highlight—absolutely delicious and full of flavor. We will stay again longer next time.
Reviewed on Jan 22, 2026
Villa Marina Lodge & Condos
Price was $1,077, price is now $767 per person
$767
per person
Apr 20 - Apr 25
found 1 day ago
Roundtrip flight included
New York (NYC) to Panama City (PTY)
9/10 Wonderful! (133 reviews)
Love that this property is at the other end of the beach from the late night partying. Walkable beach. Great restaurants nearby. The property was adding coffee makers and mini fridges the day we were leaving. Great staff, restaurant and drinks. We’ve been twice with our pooches. Will be back
Reviewed on Jul 14, 2025
Santa Cruz Hotel Deals
Hotel Bambito By Faranda Boutique, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
$100 nightly
The price is $110 total per night from Feb 18 to Feb 19
$110 total
Feb 18 - Feb 19
Total with taxes and fees
8/10 Very Good! (242 reviews)
Very clean room
Reviewed on Jan 9, 2026
Hotel Finca Lerida
Alto Quiel Los Naranjos Chiriqui
$228 nightly
The price is $251 total per night from Feb 5 to Feb 6
$251 total
Feb 5 - Feb 6
Total with taxes and fees
8.8/10 Excellent! (188 reviews)
Spotless room and bathroom, the amazing staff that treats you like family, coffee tour and tasting is a must, very good food.
Reviewed on Jan 13, 2026
Los Quetzales Ecolodge & Spa
Guadalupe Cerro Punta Chiriqui
$92 nightly
The price is $101 total per night from Feb 7 to Feb 8
$101 total
Feb 7 - Feb 8
Total with taxes and fees
8.6/10 Excellent! (33 reviews)
Staff was amazing, local foods excellent. Perfect location for hiking the vertical farms and bird watching!
Reviewed on Jan 31, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Cruz Vacation Packages
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
