Santa Cruz Vacations from $1,007
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The Latest Santa Cruz vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,290
per person
Nov 10 - Nov 16
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Beautiful historic hotel we stayed there for 5 nights with a group of 33 people celebrating my brother’s 50 th birthday. very central, you can walk to go shopping or eating and dining at the roof top restaurants in the hotel or around Casco.
The cocktails at the bar delicious and the breakfast was great variety, food was fresh. I’d rate the hotel Uber from there quick and cheap…….,10/10 great experience. The staff was also nice and very accommodating.
Reviewed on Sep 2, 2026
Santa Cruz Hotel Deals
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundableReserve now, pay when you stay
$96 nightly
$106 total
Sep 3 - Sep 4
Total with taxes and fees
8.2/10 Very Good! (267 reviews)
"Me gusto todo. La habitación con una vista increíble, el restaurante muy bien atendido y buena cómida. La piscina climatizada es genial"
Reviewed on Aug 30, 2026
Hotel Finca Lerida
Alto Quiel Los Naranjos Chiriqui
$159 nightly
$176 total
Sep 9 - Sep 10
Total with taxes and fees
8.8/10 Excellent! (210 reviews)
"Un buen ambiente para estar tranquilo con la naturaleza."
Reviewed on Aug 20, 2026
Casa Grande Bambito Resort
Calle El Manantial Paso Ancho Chiriqui
8.4/10 Very Good! (99 reviews)
"We went for 3 days to the Junior Suite 1. First day there was a wedding. Noise all night long When we got there, the TV did not work. Wifi slow and sometimes it went down. Antes on the sink, the staff told me that "usually happens". No mosquito screen. You need to sleep with windows opens, which ..."
Reviewed on Jan 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Cruz Vacation Packages
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Frequently asked questions
How to find the best Santa Cruz package deals?
Use Expedia's filters to find some terrific Santa Cruz package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or browse for Santa Cruz package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package as early as possible.
When to book a vacation package to Santa Cruz?
If you have your Santa Cruz vacation dates confirmed, book as early as you can to bag some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for impromptu escapes.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
