Santa Fe Vacations from $817

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The Latest Santa Fe vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Bella Vista
Price was $1,255, price is now $817 per person
$817
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (4,386 reviews)
Room was clean and comfortable. The staff was amazing. The food is always top tier. This was my second stay and I will definitely return

Reviewed on Nov 12, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was $1,946, price is now $1,094 per person
$1,094
per person
Jan 28 - Feb 2
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,005 reviews)
Staffs were wonderful.

Reviewed on Oct 28, 2025

Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
Price was $2,300, price is now $1,297 per person
$1,297
per person
Jan 23 - Jan 26
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
No reviews
Hotel Panamonte

Hotel Panamonte

3.5 out of 5
Price was $1,294, price is now $861 per person
$861
per person
Feb 4 - Feb 10
found 3 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.4/10 Exceptional! (121 reviews)
This is a classic, elegant property that lives up to its reputation. Quality in every regard. On par with some of the finest historic hotels in the country (and I’ve stayed at a few).

Reviewed on Sep 4, 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was $1,286, price is now $857 per person
$857
per person
Jan 24 - Jan 31
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9/10 Wonderful! (1,009 reviews)
The experience was incredible. From the facility to the staffs , thumbs up!!! Everything was just perfect !

Reviewed on Nov 10, 2025

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Santa Fe Hotel Deals

Hospedaje casa cultural wounaan

Hospedaje casa cultural wounaan

2 out of 5
Panama canal, Puerto lara Darien, Santa Fe, Darien
Fully refundable
$17 nightly
The price is $19 total per night from Nov 19 to Nov 20
$19 total
Nov 19 - Nov 20
Total with taxes and fees
7.6/10 Good! (4 reviews)
Good but they need better communicatiy
We had a great time during our visit. Apart from walking the village there isn’t much to do. We still made the most of our time and made friends with many locals. We did feel a little uncomfortable at the end of our trip as the president was complaining that we had paid in advance and he expected ...

Reviewed on Aug 22, 2025

Hospedaje casa cultural wounaan
See all 3 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Fe Vacation Packages

Santa Fe Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Population
1,500

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Frequently asked questions

How much does a Santa Fe vacation package cost?
You can grab a vacation package to this top destination from $817 on Expedia. But how much your vacation to Santa Fe costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Santa Fe?
January, July and December are great times to look for cheap Santa Fe vacation packages. Opting to travel in quieter months means you can generally find reduced prices on flights and accommodations.
How many days is enough for Santa Fe?
Generally, a handful of days is enough to check out the top sights during your Santa Fe vacation. But if you prefer to have more time to unwind or go on day tours, think about extending your trip.
How to find the best Santa Fe package deals?
Begin your search for a Santa Fe package deal by entering your travel dates and destination under our "Packages" tab. Then select some filters, like "Property type" and "Amenities," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the ideal Santa Fe package deal right away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Fe getaway off to a flying start.
Is it cheaper to book a Santa Fe vacation as a package?
You can enjoy significant savings on your Santa Fe break by booking a customized vacation package. Check the "Package" heading, then enter your destination and travel dates to browse some great flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Fe?
If you're planning a spontaneous Santa Fe trip, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can score incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later Santa Fe vacation packages?
If you're like us, you love discovering new places but don't love the big price tag that can sometimes come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the total cost of your Santa Fe break across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can secure cheap vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.