Santa Fe Vacations from $468

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Your Santa Fe Vacation

Make travel planning stress-free by reserving a vacation package to Santa Fe. Let us handle the details, so you can focus on soaking up everything this neighborhood has to offer. Some popular nearby attractions to check out during your trip to Santa Fe include Atanasio Giradot Stadium, Botero Plaza and Lights Park. Expedia is here to help put your plans into action. Book your ultimate Santa Fe vacation today.

The Latest Santa Fe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Lagoon

Hotel Lagoon

3.5 out of 5
Save 100% on your flight
Price was $747, price is now $468 per person
$468
per person
Feb 8 - Feb 13
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9.2/10 Wonderful! (286 reviews)
Nuestra suite bien preparada , espaciosa , con un a vista muy bonita . El personal de recepcion muy agradable y atento.

Reviewed on Dec 1, 2025

Aparta Suites Torre Poblado

Aparta Suites Torre Poblado

3 out of 5
El Poblado
Save 100% on your flight
Price was $1,417, price is now $747 per person
$747
per person
Jan 17 - Jan 24
found 5 hours ago
Roundtrip non-stop flight included
Fort Lauderdale (FLL) to Medellín (MDE)
8.8/10 Excellent! (863 reviews)
Muy limpio,los empleados muy atentos y un ambiente acogedor.

Reviewed on Dec 5, 2025

Hotel Estadio Real

Hotel Estadio Real

3 out of 5
Laureles - Estadio
Price was $2,083, price is now $1,259 per person
$1,259
per person
Jan 22 - Jan 27
found 16 hours ago
Roundtrip non-stop flight included
New York (JFK) to Medellín (MDE)
5.8/10 (30 reviews)
Instalaciones excelentes, desayuno muy rico y la atencion 100/10

Reviewed on Oct 16, 2024

Hotel Villa Real

Hotel Villa Real

2.5 out of 5
Laureles - Estadio
Save 100% on your flight
Price was $943, price is now $582 per person
$582
per person
Feb 12 - Feb 17
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
7.2/10 Good! (52 reviews)
Estuvo genial gracias

Reviewed on Sep 28, 2025

Hotel Med Colombia

Hotel Med Colombia

2.5 out of 5
Laureles - Estadio
Save 100% on your flight
Price was $907, price is now $563 per person
$563
per person
Jan 22 - Jan 27
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
8.2/10 Very Good! (17 reviews)
Yes, nice and clean, staff very attentive and friendly

Reviewed on Dec 5, 2025

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe
El Castillo Museum which includes heritage architecture and a castle

El Poblado

6 out of top 10 points of interest in this area
4.5/5(1,487 area reviews)

Golden Blocks brimming with commercial activity, El Poblado offers vibrant nightlife at Lleras Park, cultural attractions like El Castillo Museum, and ample shopping options with multiple malls. Accessible via Medellín Metro and bus lines.

Find hotels in El Poblado

Santa Fe Hotel Deals

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $76 total per night from Jan 7 to Jan 8
$76 total
Jan 7 - Jan 8, 2026
9/10 Wonderful! (1,016 reviews)
Great!

Reviewed on Dec 5, 2025

Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
$69 nightly
The price is $69 total per night from Dec 14 to Dec 15
$69 total
Dec 14 - Dec 15
8.8/10 Excellent! (1,768 reviews)
I wish I should have ask for a room on the back street of the property

Reviewed on Dec 6, 2025

Hotel Dorado La 70
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A Medellín
Fully refundable
$73 nightly
The price is $73 total per night from Dec 9 to Dec 10
$73 total
Dec 9 - Dec 10
9.2/10 Wonderful! (273 reviews)
Best place to stay, convenience and entertainment in poblado. Hotel was clean, very well upgraded, room was clean and welcoming, staff was excellent, Juan Jose at the front desk offered very attentive and efficient service and also informative. Overall I give the hotel a 9/10. One of the best hotels ...

Reviewed on Dec 2, 2025

Calle Flora Hotel by Jalo
See all 4,401 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Fe

Such an impressive mall. With the heat that we struggled to adapt to in Medellin, we often found ourselves seeking out the comfort of air conditioned malls. Although, malls are not are favorite thing, this was definitely our favorite mall in Medellin. A must see, if you're in the area. #colombia #shopping #travel

Santafé Mall

4.5/5(485 reviews)

During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the top-notch restaurants or lively bars in this walkable area.

Santafé Mall
Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city

Botero Plaza

4.5/5(476 reviews)

Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.

Botero Plaza
The Colombians are big supporters of soccer and watching a soccer game of Medellin Independente or Nacional in the Estadio in Medellin is a very special experience! 90 mins of singing, jumping, playing the drums and supportung the team. Be careful to go to the South or North area in the stadium, that's where the very extreme fans are. Seats in the Occidental and Oriental area are good places to watch the games.

Atanasio Giradot Stadium

4.5/5(122 reviews)

Catch an event at Atanasio Giradot Stadium during your trip to Medellín. Check out the shops and lively bars in this walkable area.

Atanasio Giradot Stadium

Things to do

Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

$27
per adult
96% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
Pablo Escobar Tour Medellin

Pablo Escobar Tour : Museum, History and Beer

$40
per adult
90% of travellers recommend
Pablo Escobar Tour : Museum, History and Beer
See all activities in Medellin
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.