Santa Fe Vacations from $402

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Your Santa Fe Vacation

Make travel planning stress-free by reserving a vacation package to Santa Fe. Let us handle the details, so you can focus on soaking up everything this neighborhood has to offer. Some popular nearby attractions to check out during your trip to Santa Fe include Atanasio Giradot Stadium, Botero Plaza and Lights Park. Expedia is here to help put your plans into action. Book your ultimate Santa Fe vacation today.

The Latest Santa Fe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Living 35 Suites

Hotel Living 35 Suites

4 out of 5
La América
Save 100% on your flight
Price was $769, price is now $402 per person
$402
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9.6/10 Exceptional! (67 reviews)
buen tamaño de habitaciones, desayuno bueno, personal amable

Reviewed on Sep 7, 2025

Hotel Tahití

Hotel Tahití

3.5 out of 5
Price was $1,499, price is now $449 per person
$449
per person
Oct 15 - Oct 19
found 1 day ago
Roundtrip non-stop flight included
San Juan (SJU) to Medellín (MDE)
8.8/10 Excellent! (9 reviews)
Blues Suites Medellin

Blues Suites Medellin

4 out of 5
El Poblado
Save 100% on your flight
Price was $923, price is now $499 per person
$499
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9/10 Wonderful! (892 reviews)
Breakfast offer is limited and the charge you extra for even a escondidas VIP of coffee. It is not Buffet. Room maintenace Needs improvement . I had an ants problem in my room and they were unable to solve. I had to purchance ant keeler and solve it myself.

Reviewed on Sep 6, 2025

Wellcomm Spa & Hotel

Wellcomm Spa & Hotel

4 out of 5
El Poblado
Save 100% on your flight
Price was $925, price is now $512 per person
$512
per person
Nov 30 - Dec 6
found 1 day ago
Roundtrip flight included
Fort Lauderdale (FLL) to Medellín (MDE)
9.4/10 Exceptional! (336 reviews)
Friendly staff, good location, nice ambience, good Spa.

Reviewed on Sep 3, 2025

EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Save 100% on your flight
Price was $2,926, price is now $1,661 per person
$1,661
per person
Nov 17 - Nov 20
found 16 hours ago
Roundtrip non-stop flight included
New York (JFK) to Medellín (MDE)
10/10 Exceptional! (2 reviews)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe
El Castillo Museum which includes heritage architecture and a castle

El Poblado

6 out of top 10 points of interest in this area
4.5/5(1,487 area reviews)

Golden Blocks brimming with commercial activity, El Poblado offers vibrant nightlife at Lleras Park, cultural attractions like El Castillo Museum, and ample shopping options with multiple malls. Accessible via Medellín Metro and bus lines.

Find hotels in El Poblado

Santa Fe Hotel Deals

Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66, Laureles, Medellín
Fully refundableReserve now, pay when you stay
$49 nightly
The price is $49 total per night from Sep 24 to Sep 25
$49 total
Sep 24 - Sep 25
Hotel Dorado La 70
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F, Medellín, Antioquia
Fully refundable
$66 nightly
The price is $66 total per night from Sep 10 to Sep 11
$66 total
Sep 10 - Sep 11
Heiss Hotel By Jalo
York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $144 total per night from Sep 18 to Sep 19
$144 total
Sep 18 - Sep 19
York Luxury Suites Medellín
See all 4,317 properties in Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Fe

Such an impressive mall. With the heat that we struggled to adapt to in Medellin, we often found ourselves seeking out the comfort of air conditioned malls. Although, malls are not are favorite thing, this was definitely our favorite mall in Medellin. A must see, if you're in the area. #colombia #shopping #travel

Santafé Mall

During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the top-notch restaurants or lively bars in this walkable area.

Santafé Mall
Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city

Botero Plaza

Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.

Botero Plaza
The Colombians are big supporters of soccer and watching a soccer game of Medellin Independente or Nacional in the Estadio in Medellin is a very special experience! 90 mins of singing, jumping, playing the drums and supportung the team. Be careful to go to the South or North area in the stadium, that's where the very extreme fans are. Seats in the Occidental and Oriental area are good places to watch the games.

Atanasio Giradot Stadium

Catch an event at Atanasio Giradot Stadium during your trip to Medellín. Check out the shops and top-notch restaurants in this walkable area.

Atanasio Giradot Stadium

Things to do

Queer Graffiti Private Tour

Queer Graffiti Private Tour

$300
per adult
Queer Graffiti Private Tour
Pablo Escobar Tour Medellin

Pablo Escobar Tour Medellin

$32
per adult
86% of travellers recommend
Pablo Escobar Tour Medellin
See all activities in Medellin
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.