Antioquia Vacations & Trips from $336

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Your Antioquia Vacation

Leave all the planning up to us with an Antioquia vacation package. With everything arranged before you jet off, the only thing you'll need to do is relax and experience this destination's culture and charm. With so many things to explore on a trip to Antioquia, it can be tricky to know where to begin. Kick off your travels in Medellin at Santafé Mall and Lleras Park — two much-loved attractions here. Another city worth adding to your itinerary is Guatapé. Be sure not to miss Peñol-Guatapé Reservoir and Parque Comfama. From the instant you book your Antioquia vacation to when you return home, Expedia has your back each step of the way.

Top destinations in Antioquia

Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city
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Medellin

Medellin

The Latest Antioquia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Palma Sevilla Medellin

Hotel Palma Sevilla Medellin

2 out of 5
Aranjuez
Save 100% on your flight
Price was $594, price is now $336 per person
$336
per person
Feb 15 - Feb 21
found 10 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Medellín (MDE)
No reviews
EP Casa Uribe Architecture Art & Nature

EP Casa Uribe Architecture Art & Nature

4 out of 5
El Poblado
Save 100% on your flight
Price was $6,374, price is now $3,146 per person
$3,146
per person
Jan 5 - Jan 8
found 12 hours ago
Roundtrip non-stop flight included
New York (NYC) to Medellín (MDE)
20/10 Exceptional! (3 reviews)
The house is extremely comfortable and spacious. Luxury amenities that made us feel at home. The pool, jacuzzi and sauna. Graciela the house keeper and Charles our private chef made our stay amazing. It was nice that they had a lunch and dinner menu available for those days we wanted to stay in. Probably one of the best stays in Medellin. The location is just minutes away from Provenza and surroundings. Manuela the host was super attentive, helping us with reservations at restaurants.

Reviewed on Mar 24, 2025

Aparta Suites Torre Poblado

Aparta Suites Torre Poblado

3 out of 5
El Poblado
Save 100% on your flight
Price was $1,131, price is now $600 per person
$600
per person
Feb 5 - Feb 15
found 1 day ago
Roundtrip non-stop flight included
Miami (MIA) to Medellín (MDE)
17.6/10 Exceptional! (863 reviews)
Desde que llegamos hasta que nos fuimos todo fue espectacular. Nos recibieron con muchas amabilidad, el cuarto amplio y limpio. El desayuno bufet espectacular y el servicio excelente. La ubicación del hotel super accesible para caminar para encontrar de todo por ejemplo restaurantes, entretenimiento y ir de compras. Definitivamente este sera mi lugar cuando vuelva.

Reviewed on Oct 16, 2025

Luxury Home In Las Lomas

Luxury Home In Las Lomas

4 out of 5
El Poblado
Price was $3,284, price is now $1,856 per person
$1,856
per person
Dec 27 - Jan 3
found 19 hours ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
No reviews
Luxury Home In Aguacatala

Luxury Home In Aguacatala

4 out of 5
El Poblado
Save 100% on your flight
Price was $2,178, price is now $1,248 per person
$1,248
per person
Jan 9 - Jan 15
found 1 day ago
Roundtrip flight included
San Juan (SJU) to Medellín (MDE)
4/10 (1 review)

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Where to stay in Antioquia

Get a lay of the land and find the perfect place to stay Learn more about Antioquia
El Castillo Museum which includes heritage architecture and a castle

El Poblado

6 out of top 10 points of interest in this area
4.5/5(1,487 area reviews)

Golden Blocks brimming with commercial activity, El Poblado offers vibrant nightlife at Lleras Park, cultural attractions like El Castillo Museum, and ample shopping options with multiple malls. Accessible via Medellín Metro and bus lines.

Find hotels in El Poblado

Best Places to Vacation in Antioquia

1. Find your perfect Medellin vacation

Medellín, located in the beautiful Antioquia region of Colombia, offers a vibrant atmosphere perfect for a family vacation. Whether you're looking for cozy cafes, stunning natural parks, lively bars, or shopping opportunities, this city has it all. Explore the rich history and culture by visiting museums, indulge in delicious dining options, and enjoy live music and entertainment. Take guided tours to discover the hidden gems of Medellín. With its warm and welcoming locals, breathtaking views, and a wide range of activities, Medellín is the perfect destination for a memorable family vacation.

  • Travelers tend to stay 4 days in Medellin

2. Discover Guatapé with our vacation deals

Guatapé, located in Antioquia, Colombia, offers a vibrant and diverse atmosphere for outdoor vacation experiences. With its stunning natural landscapes and geographical affinities, it is the perfect destination for adventure enthusiasts. Visitors can indulge in activities such as ziplining, rock climbing, kayaking, fishing, horseback riding, and swimming in the beautiful lakes and waterfalls. Guatapé also provides ample opportunities for sports lovers. Whether you are seeking a thrilling experience or simply want to immerse yourself in the breathtaking scenery, Guatapé offers a wide range of destination activities and things to do that will make your vacation unforgettable.

  • The peak season is from June to August
  • The off-peak season is from September to November
  • Travelers tend to stay 2 days in Guatapé

3. Escape to Rionegro with a vacation package

Rionegro, Antioquia, Colombia offers a diverse and vibrant atmosphere for a family vacation. With its beautiful landscapes and proximity to nature, it is perfect for outdoor activities such as hiking and wildlife exploration. The city also boasts luxurious accommodations, spas, and gardens, providing opportunities for relaxation and rejuvenation. For those interested in culture and education, Rionegro is home to a renowned university and offers a rich historical heritage. Whether you're looking for adventure, tranquility, or a mix of both, Rionegro has something to offer for everyone in the family.

  • Travelers tend to stay 2 days in Rionegro

4. Experience Guarne with a travel package

Jericó, in the Antioquia region of Colombia, offers a charming atmosphere for outdoor enthusiasts. Surrounded by stunning natural beauty, the town is the perfect base for exploring the nearby national parks and engaging in various outdoor activities. Whether you prefer hiking through lush forests, birdwatching, or simply enjoying the breathtaking landscapes, Jericó has it all. Additionally, the town itself boasts a vibrant cultural scene, with local markets, traditional architecture, and friendly locals. Immerse yourself in the local atmosphere and experience the rich natural wonders that Jericó has to offer.

  • The peak season is from July to September
  • The off-peak season is from October to December
  • Travelers tend to stay 3 days in Guarne

6. Plan your dream getaway to Envigado

Santa Fe de Antioquia offers a unique outdoor vacation experience. The town's historical charm is complemented by beautiful flowers and a relaxing atmosphere. Visitors can explore the town's monuments, including the stunning cathedral, and immerse themselves in local festivals. The nearby river provides opportunities for outdoor activities like swimming and boating. Art enthusiasts will appreciate the town's art galleries, theaters, and museums. With its diverse range of attractions, Santa Fe de Antioquia is the perfect destination for those seeking a combination of history, culture, and natural beauty.

  • The peak season is from January to March
  • The off-peak season is from October to December
  • Travelers tend to stay 5 days in Envigado

5. Create memories in Santa Fe de Antioquia with a vacation package

Envigado, in the beautiful region of Antioquia, Colombia, offers a wonderful atmosphere and experience for a family vacation. With its geographic affinities, this city is perfect for family-friendly activities, business opportunities, romantic getaways, shopping adventures, and dining experiences. Whether you're looking for outdoor activities or cultural attractions, Envigado has it all. Explore the local destination activities and discover the countless things to do, ensuring a memorable trip for the whole family. From stunning landscapes to vibrant city life, Envigado is a hidden gem waiting to be explored.

  • The peak season is from December to February
  • The off-peak season is from September to November
  • Travelers tend to stay 2 days in Santa Fe de Antioquia

Find the Best Antioquia Vacation Packages

Antioquia Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Top Sights
Lleras Park, Botero Plaza and Rock of Guatapé

Antioquia Hotel Deals

Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $67 total per night from Nov 26 to Nov 27
$67 total
Nov 26 - Nov 27
9/10 Wonderful! (981 reviews)
Very nice and clean hotel.

Reviewed on Nov 20, 2025

Heiss Hotel By Jalo
Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
$63 nightly
The price is $63 total per night from Dec 15 to Dec 16
$63 total
Dec 15 - Dec 16
8.8/10 Excellent! (1,724 reviews)
Love this hotel! Clean, location, staff

Reviewed on Nov 13, 2025

Hotel Dorado La 70
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

3.5 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
$62 nightly
The price is $62 total per night from Nov 28 to Nov 29
$62 total
Nov 28 - Nov 29
9.2/10 Wonderful! (250 reviews)
Staff were professional and helpful... Oscar in the night shift was a true gentleman

Reviewed on Nov 19, 2025

Calle Flora Hotel by Jalo
See all 5,284 properties in Antioquia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Vacations
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Frequently asked questions

How much does an Antioquia vacation package cost?
We make it easy to explore the world, with Antioquia packages starting from just $336. You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a couple of activities and tours to your itinerary?
How do I get a cheap travel package to Antioquia?
You'll save a pile of money if you bundle your car rentals, flights and hotels into an Antioquia vacation package. Sometimes cheap means fewer choices. But not with Expedia. We offer more than 550 air carriers and 1,000,000 hotels across the world, so you'll always have plenty of options to choose from. Want to save even more? Add some interesting activities to your package deal and unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
How far in advance should I book my Antioquia vacation?
It can be hard to know exactly when is the perfect time to book your Antioquia trip. But generally the earlier you book, the cheaper the prices. Sometimes, you can lock in your flights and hotels nearly a year prior to departure. If you're thinking of a last-minute getaway, no need to worry! There are fantastic bargains advertised on Expedia every single day.
What does an Expedia Antioquia travel package include?
From hotels and flights to rental cars, Expedia can help you shape an Antioquia package that suits you. Vacationing for a few weeks? Give some thought to a rental car, flight and hotel bundle. If you're taking a quick break, a hotel and airfare deal could be what you're after. Tours and activities can be added once you've made your booking. Our packages make it simple to plan and save.
What should I know before booking an Antioquia travel package?
You can save a tidy sum by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on activities or tours. Your next awesome adventure is only a few clicks away.
Can I choose my airline with an Antioquia Expedia vacation package?
Yes — that's one of the best things about an Expedia package. You're in charge! We have access to more than 550 partner airlines all over the world, so you have options galore when arranging your Antioquia getaway.
Does Expedia offer Book Now, Pay Later Antioquia vacation packages?
Thanks to our partnership with online lender Affirm, you can opt to Book Now, Pay Later. You can tailor your trip with Expedia packages, so why not customize a payment plan too?
If I'm not able to travel, can I cancel my Antioquia vacation package?
Don't stress if you're rethinking your Antioquia vacation package — you can cancel or change your booking. And if you've booked it within the last 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we're ready to help.

Discover the most popular places to visit in Antioquia

Such an impressive mall. With the heat that we struggled to adapt to in Medellin, we often found ourselves seeking out the comfort of air conditioned malls. Although, malls are not are favorite thing, this was definitely our favorite mall in Medellin. A must see, if you're in the area. #colombia #shopping #travel

Santafé Mall

4.5/5(485 reviews)

During your visit to Medellín, you can search for that perfect souvenir at Santafé Mall. Check out the top-notch restaurants or lively bars in this walkable area.

Santafé Mall
Botero Square Sculpture Park featuring a church or cathedral, a square or plaza and a city

Botero Plaza

4.5/5(476 reviews)

Walk among comically obese statues made by the illustrious artist Fernando Botero in this spacious plaza full of artisans and restaurants.

Botero Plaza
The Colombians are big supporters of soccer and watching a soccer game of Medellin Independente or Nacional in the Estadio in Medellin is a very special experience! 90 mins of singing, jumping, playing the drums and supportung the team. Be careful to go to the South or North area in the stadium, that's where the very extreme fans are. Seats in the Occidental and Oriental area are good places to watch the games.

Atanasio Giradot Stadium

4.5/5(122 reviews)

Catch an event at Atanasio Giradot Stadium during your trip to Medellín. Check out the shops and lively bars in this walkable area.

Atanasio Giradot Stadium

What to do in Antioquia

Medellín: Comuna 13 District Tour with Cable Car Ride

Medellín: Comuna 13 District Tour with Cable Car Ride

$27
per adult
96% of travellers recommend
Medellín: Comuna 13 District Tour with Cable Car Ride
Photos we take of those who choose a private tour

Jetskiing in Guatapé Antioquia

$100
per traveler
Jetskiing in Guatapé Antioquia
See all activities in Antioquia
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.