Antioquia Vacations & Trips from $494

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Your Antioquia Vacation

Leave all the planning up to us with an Antioquia vacation package. With everything arranged before you jet off, the only thing you'll need to do is relax and experience this destination's culture and charm. With so many things to explore on a trip to Antioquia, it can be tricky to know where to begin. Kick off your travels in Medellin at Santafé Mall and Lleras Park — two much-loved attractions here. Another city worth adding to your itinerary is Guatapé. Be sure not to miss Peñol-Guatapé Reservoir and Parque Comfama. From the instant you book your Antioquia vacation to when you return home, Expedia has your back each step of the way.

Top destinations in Antioquia

The Latest Antioquia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Tau House
EP Casa Uribe Architecture Art & Nature
Hotel Estadio Real
Sonata 44 Hotel Laureles
Hotel Lomas 10

Where to stay in Antioquia

Get a lay of the land and find the perfect place to stay Learn more about Antioquia

Best Places to Vacation in Antioquia

1. Find your perfect Medellin vacation

Medellín, located in the beautiful Antioquia region of Colombia, offers a vibrant atmosphere perfect for a family vacation. Whether you're looking for cozy cafes, stunning natural parks, lively bars, or shopping opportunities, this city has it all. Explore the rich history and culture by visiting museums, indulge in delicious dining options, and enjoy live music and entertainment. Take guided tours to discover the hidden gems of Medellín. With its warm and welcoming locals, breathtaking views, and a wide range of activities, Medellín is the perfect destination for a memorable family vacation.

  • Travelers tend to stay 4 days in Medellin

2. Discover Guatapé with our vacation deals

Guatapé, located in Antioquia, Colombia, offers a vibrant and diverse atmosphere for outdoor vacation experiences. With its stunning natural landscapes and geographical affinities, it is the perfect destination for adventure enthusiasts. Visitors can indulge in activities such as ziplining, rock climbing, kayaking, fishing, horseback riding, and swimming in the beautiful lakes and waterfalls. Guatapé also provides ample opportunities for sports lovers. Whether you are seeking a thrilling experience or simply want to immerse yourself in the breathtaking scenery, Guatapé offers a wide range of destination activities and things to do that will make your vacation unforgettable.

  • The peak season is from June to August
  • The off-peak season is from September to November
  • Travelers tend to stay 2 days in Guatapé

3. Escape to Rionegro with a vacation package

Rionegro, Antioquia, Colombia offers a diverse and vibrant atmosphere for a family vacation. With its beautiful landscapes and proximity to nature, it is perfect for outdoor activities such as hiking and wildlife exploration. The city also boasts luxurious accommodations, spas, and gardens, providing opportunities for relaxation and rejuvenation. For those interested in culture and education, Rionegro is home to a renowned university and offers a rich historical heritage. Whether you're looking for adventure, tranquility, or a mix of both, Rionegro has something to offer for everyone in the family.

  • Travelers tend to stay 2 days in Rionegro

4. Experience Guarne with a travel package

Jericó, in the Antioquia region of Colombia, offers a charming atmosphere for outdoor enthusiasts. Surrounded by stunning natural beauty, the town is the perfect base for exploring the nearby national parks and engaging in various outdoor activities. Whether you prefer hiking through lush forests, birdwatching, or simply enjoying the breathtaking landscapes, Jericó has it all. Additionally, the town itself boasts a vibrant cultural scene, with local markets, traditional architecture, and friendly locals. Immerse yourself in the local atmosphere and experience the rich natural wonders that Jericó has to offer.

  • The peak season is from July to September
  • The off-peak season is from October to December
  • Travelers tend to stay 3 days in Guarne

6. Plan your dream getaway to Envigado

Santa Fe de Antioquia offers a unique outdoor vacation experience. The town's historical charm is complemented by beautiful flowers and a relaxing atmosphere. Visitors can explore the town's monuments, including the stunning cathedral, and immerse themselves in local festivals. The nearby river provides opportunities for outdoor activities like swimming and boating. Art enthusiasts will appreciate the town's art galleries, theaters, and museums. With its diverse range of attractions, Santa Fe de Antioquia is the perfect destination for those seeking a combination of history, culture, and natural beauty.

  • The peak season is from January to March
  • The off-peak season is from October to December
  • Travelers tend to stay 5 days in Envigado

5. Create memories in Santa Fe de Antioquia with a vacation package

Envigado, in the beautiful region of Antioquia, Colombia, offers a wonderful atmosphere and experience for a family vacation. With its geographic affinities, this city is perfect for family-friendly activities, business opportunities, romantic getaways, shopping adventures, and dining experiences. Whether you're looking for outdoor activities or cultural attractions, Envigado has it all. Explore the local destination activities and discover the countless things to do, ensuring a memorable trip for the whole family. From stunning landscapes to vibrant city life, Envigado is a hidden gem waiting to be explored.

  • The peak season is from December to February
  • The off-peak season is from September to November
  • Travelers tend to stay 2 days in Santa Fe de Antioquia

Best months to visit Antioquia

Looking for the best time to visit Antioquia? Our table will help you. Antioquia boasts a year-round average temperature of 64.1°F, reaching a peak of 66.2°F in July, its warmest month, and dropping to an average low of 59.2°F in August, the coolest month. The annual rainfall averages 299.3mm, with May experiencing the heaviest showers, while January is the driest month.

Monthcalendar iconTemperature (Fahrenheit)temperature iconRainfallrain iconCloud coveragecloud icon
January59.7Light RainMostly Cloudy
February64.8Light RainMostly Cloudy
March64.8Frequent RainMostly Cloudy
April65.3Frequent RainMostly Cloudy
May65.5Frequent RainMostly Cloudy
June65.7Moderate RainMostly Cloudy
July66.2Moderate RainMostly Cloudy
August59.2Frequent RainMostly Cloudy
September66.0Moderate RainMostly Cloudy
October64.2Frequent RainMostly Cloudy
November63.9Frequent RainMostly Cloudy
December63.7Light RainMostly Cloudy

How to save money on a vacation to Antioquia

  • Combine your flights with hotels or car rentals to save money, especially in Antioquia.
  • Take advantage of Expedia's OneKey program to collect points and save money.
  • Utilize the helpful search filters on Expedia to find the perfect accommodation within your price range.
  • Consider traveling during the low season in Antioquia, which is typically from May to July, for the most budget-friendly options.
  • Use the search filter for price limits on Expedia to find a vacation that suits your budget.
  • Discover the best vacation experience for you by using the travel experience filter on Expedia, whether it's a family, romantic, or adventurous getaway.

Antioquia Essential Information

Language
Spanish
Currency
Colombian pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Jose Maria Cordova Intl. Airport (MDE)
Top Sights
Lleras Park, Botero Plaza and Rock of Guatapé

Antioquia Hotel Deals

Hotel Dorado La 70

Hotel Dorado La 70

4 out of 5
Carrera 70 No 44 B-66, Laureles, Medellín
Fully refundableReserve now, pay when you stay
The price is $64 total per night from Oct 22 to Oct 23
$64 total
per night
Oct 22 - Oct 23
8.6/10 Excellent! (1,658 reviews)
My stay
"The hotel sits in a busy nightlife area. The noise at night is ongoing until 4am. Also, the bathroom toilet paper is in one of those dispensers that holds a big round roll. However it is difficult to keep the toilet paper from breaking, and then you have to dig underneath to find the start of the ..."

Reviewed on Oct 6, 2025

Hotel Dorado La 70
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
The price is $60 total per night from Oct 19 to Oct 20
$60 total
per night
Oct 19 - Oct 20
9/10 Wonderful! (869 reviews)
"good place to stay and lasts of place to eat"

Reviewed on Oct 6, 2025

Heiss Hotel By Jalo
York Luxury Suites Medellín

York Luxury Suites Medellín

4 out of 5
Carrera 43a 17sur 63, Medellín, Antioquia
Fully refundableReserve now, pay when you stay
The price is $131 total per night from Oct 21 to Oct 22
$131 total
per night
Oct 21 - Oct 22
9.4/10 Exceptional! (1,349 reviews)
"Good!"

Reviewed on Oct 7, 2025

York Luxury Suites Medellín
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Antioquia vacation package cost?
We make it easy to explore the world, with Antioquia packages starting from just $494. You'll have the flexibility to combine your preferred hotels, airlines and car rental. For the ultimate escape, why not add a couple of activities and tours to your itinerary?
How do I get a cheap travel package to Antioquia?
You'll save a pile of money if you bundle your car rentals, flights and hotels into an Antioquia vacation package. Sometimes cheap means fewer choices. But not with Expedia. We offer more than 550 air carriers and 1,000,000 hotels across the world, so you'll always have plenty of options to choose from. Want to save even more? Add some interesting activities to your package deal and unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
How far in advance should I book my Antioquia vacation?
It can be hard to know exactly when is the perfect time to book your Antioquia trip. But generally the earlier you book, the cheaper the prices. Sometimes, you can lock in your flights and hotels nearly a year prior to departure. If you're thinking of a last-minute getaway, no need to worry! There are fantastic bargains advertised on Expedia every single day.
What does an Expedia Antioquia travel package include?
From hotels and flights to rental cars, Expedia can help you shape an Antioquia package that suits you. Vacationing for a few weeks? Give some thought to a rental car, flight and hotel bundle. If you're taking a quick break, a hotel and airfare deal could be what you're after. Tours and activities can be added once you've made your booking. Our packages make it simple to plan and save.
What should I know before booking an Antioquia travel package?
You can save a tidy sum by bundling your hotels, airfares and rental cars. Once you've created your package, you can add on activities or tours. Your next awesome adventure is only a few clicks away.
Can I choose my airline with an Antioquia Expedia vacation package?
Yes — that's one of the best things about an Expedia package. You're in charge! We have access to more than 550 partner airlines all over the world, so you have options galore when arranging your Antioquia getaway.
Does Expedia offer Book Now, Pay Later Antioquia vacation packages?
Thanks to our partnership with online lender Affirm, you can opt to Book Now, Pay Later. You can tailor your trip with Expedia packages, so why not customize a payment plan too?
If I'm not able to travel, can I cancel my Antioquia vacation package?
Don't stress if you're rethinking your Antioquia vacation package — you can cancel or change your booking. And if you've booked it within the last 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your hotel, airline or car rental company. We totally understand your circumstances can suddenly change, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we're ready to help.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.