Santa Fe Vacations from $499

Book a Hotel + Flight or Car together to unlock savings

Your Santa Fe Vacation

Experience everything Santa Fe has to offer with a customized Santa Fe vacation package. From its cafes and shopping to its dining, it's not hard to be charmed by this food-lovers neighborhood. Start your trip to Santa Fe by checking out nearby attractions such as Paseo Interlomas, Santa Fe Center Mall and Anahuac University. Stop daydreaming and start doing. When it's time to lock in your vacation to Santa Fe, Expedia will help get you there.

The Latest Santa Fe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Mark Hotel
Casa de la Luz Hotel Boutique
HOTEL LUCA
Marquis Sky Suites
Live Aqua Ciudad de México Bosques de las Lomas

Things to do in and around Santa Fe

Santa Fe, Mexico, offers a vibrant mix of activities perfect for family, business, and city-themed vacations. Visitors can explore friendly attractions, indulge in history tours, and enjoy various family activities. Don't miss the shopping mall center and local shopping areas for a delightful retail experience. For relaxation, spa services are also available, ensuring a well-rounded visit to this charming city.

Shopping

Experience shopping in Santa Fe at the Santa Fe Center Mall, boasting a vibrant atmosphere with entertainment and family-friendly options. Just 3 miles away, Paseo Interlomas offers more shopping and fun, while Bazar del Sabado, located 5 miles from Santa Fe, presents a unique public market experience.

Recreation

Blue Stadium offers an energetic atmosphere perfect for sports enthusiasts, just 6 miles from Santa Fe. Experience culture and entertainment at the Insurgentes Theater, located 5 miles away, ideal for a romantic night out. Enjoy the outdoors at Cuernavaca Country Club, also 5 miles from Santa Fe, with scenic golfing opportunities.

Adventure

Experience the excitement at KidZania Santa Fe, where kids can engage in fun role-playing activities in a vibrant arcade environment. For thrill-seekers, K1 Speed Mexico Garden offers exhilarating kart racing. Don't miss KBR Kartódromo Internacional, located 4 miles away, for an adrenaline-pumping racing experience.

Nightlife

Santa Fe's nightlife offers a vibrant mix of upscale lounges and lively bars. Enjoy cocktails at the chic Hotel Santa Fe, or dance the night away at La Santa. For a more laid-back vibe, visit the cozy Cafe de la Plaza for drinks and live music.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Fe

Santa Fe offers a vibrant mix of urban attractions perfect for city-themed, family, or business vacations. Visitors can explore urban parks, event and conference venues, and modern colleges, making it an ideal destination for those seeking cultural experiences and family-friendly activities. Whether you're interested in the local culture or simply enjoying the city atmosphere, Santa Fe has something for everyone.

  • World Trade Center Mexico City: Experience the vibrant energy of this iconic skyscraper, which offers stunning panoramic views of the city from its observation deck. The surrounding area is filled with shopping, dining, and cultural experiences, making it a perfect spot to immerse yourself in the local lifestyle.
  • Frida Kahlo Museum: Step into the world of the renowned artist Frida Kahlo at this historic house, which showcases her life and work. The museum is filled with personal artifacts and colorful displays, providing a deep dive into her unique artistic vision and the cultural context of Mexico.
  • Auditorio Nacional: Enjoy an exhilarating experience at this premier entertainment venue, known for hosting concerts, operas, and cultural events. Its impressive architecture and acoustics make it a must-visit for families and entertainment enthusiasts alike.

Best time to go to Santa Fe

The best time to visit Santa Fe can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Fe falls in May, when visitor numbers are slightly high and weather is sunny with no rain. The coolest average temperature around Santa Fe falls in January, visitor numbers are slightly low and weather is sunny with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.7°F (14.3°C)No RainSunnySlightly LowAverage
February61.3°F (16.3°C)No RainSunnyAverageSlightly High
March64.8°F (18.2°C)No RainSunnySlightly HighAverage
April67.6°F (19.8°C)No RainSunnyAverageAverage
May68.4°F (20.2°C)No RainSunnySlightly HighAverage
June65.3°F (18.5°C)Light RainMostly SunnyAverageAverage
July62.4°F (16.9°C)Moderate RainMostly SunnyAverageSlightly Low
August62.1°F (16.7°C)Moderate RainMostly SunnyAverageSlightly Low
September61.3°F (16.3°C)Light RainMostly SunnySlightly HighAverage
October60.4°F (15.8°C)Light RainMostly SunnySlightly LowSlightly High
November59.2°F (15.1°C)No RainSunnyAverageSlightly High
December58.5°F (14.7°C)No RainSunnySlightly LowSlightly Low

Tips to save on your trip to Santa Fe

  • Combine your flights, hotels and car rentals on Expedia—bundling can result in significant savings.
  • Consider traveling during the off-peak season (typically July to August and December) for more affordable package holidays to Santa Fe.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Where to stay in Santa Fe

Find the best Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Santa Fe

Santa Fe Hotel Deals

Camino Real Santa Fe

Camino Real Santa Fe

5 out of 5
Mexico City
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $91 total per night from Dec 5 to Dec 6
$91 total
Dec 5 - Dec 6
Total with taxes and fees
9/10 Wonderful! (2,640 reviews)
Buffet good food

Reviewed on Nov 14, 2025

Camino Real Santa Fe
Stadía Suites Mexico City Santa Fe

Stadía Suites Mexico City Santa Fe

4 out of 5
Juan Salvador Agraz # 60, Colonia Lomas de Santa Fe, Mexico City, CDMX
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $97 total per night from Nov 15 to Nov 16
$97 total
Nov 15 - Nov 16
Total with taxes and fees
9/10 Wonderful! (1,155 reviews)
Yes. Only suggestion is to have a hair dryer for the ladies and it would be nice if you threw a couple of water bottles per stay even if at a charge. We arrived very late at night and had to go to a convenience store for the water. Everything else was great. Thanks.

Reviewed on Oct 30, 2025

Stadía Suites Mexico City Santa Fe
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundable
$134 nightly
The price is $160 total per night from Nov 24 to Nov 25
$160 total
Nov 24 - Nov 25
Total with taxes and fees
8.6/10 Excellent! (11,677 reviews)
Only one hook for towels in the bathroom.

Reviewed on Nov 12, 2025

Camino Real Aeropuerto Mexico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Fe

Things to do

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.