Santa Inés Vacations from $240

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Inés Vacation

Entertainment, food, art and more … There's so much to discover with a Santa Inés vacation package. And with the ability to easily customize your city break, you know it'll be one to remember. When the time comes to get out and see the sights, be sure to include Maquipucuna Cloud Forest Reserve and Bellavista Cloud Forest Reserve on the to-do list for your trip to Santa Inés. Expedia can help you escape your routine. Tailor your vacation to Santa Inés to suit your style of travel, whatever that may look like.

The Latest Santa Inés Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Dec 26 - Dec 31

    Hotel Quito + Flight

    Gonzalez Suarez
    5 nights
    3.5 star property
    8.4/10 - Very good (306 reviews)
    Roundtrip • Guayaquil (GYE) - Quito (UIO)
    GYE - UIO • Nonstop UIO - GYE • Nonstop
    $465
    $240
    per traveler
    found 1 day ago
    Hotel Quito
  • Dec 26 - Dec 31

    Vieja Cuba Hotel + Flight

    Colón
    5 nights
    3.0 star property
    9.2/10 - Wonderful (426 reviews)
    "What an amazing hotel! You must stay here if you’re visiting Quito! The staff are incredibly friendly and helpful. The breakfast is amazing. You are close to old town and other monuments. The hotel is very clean"
    Reviewed November 6, 2026
    Roundtrip • Guayaquil (GYE) - Quito (UIO)
    GYE - UIO • Nonstop UIO - GYE • Nonstop
    $423
    $243
    per traveler
    found 1 day ago
    Vieja Cuba Hotel
  • Dec 26 - Dec 31

    Hotel Reina Isabel + Flight

    La Mariscal
    5 nights
    3.5 star property
    9.0/10 - Wonderful (1,003 reviews)
    Roundtrip • Guayaquil (GYE) - Quito (UIO)
    GYE - UIO • Nonstop UIO - GYE • Nonstop
    $420
    $253
    per traveler
    found 1 day ago
    Hotel Reina Isabel
  • Dec 26 - Dec 31

    Rio Amazonas Hotel + Flight

    La Mariscal
    5 nights
    3.5 star property
    8.4/10 - Very good (334 reviews)
    Roundtrip • Guayaquil (GYE) - Quito (UIO)
    GYE - UIO • Nonstop UIO - GYE • Nonstop
    $405
    $244
    per traveler
    found 1 day ago
    Rio Amazonas Hotel
  • Dec 26 - Dec 31

    Casa Hotel Las Plazas + Flight

    Quito Historic Center
    5 nights
    3.0 star property
    9.6/10 - Exceptional (113 reviews)
    "A lovely historic building with a warm welcome and well appointed room. Breakfast hosted by Lucia was exceptional and more than I have ever experienced before, a wonderful personal experience. I would certainly stay here again and I can recommend it to others who are in the area."
    Reviewed September 15, 2026
    Roundtrip • Guayaquil (GYE) - Quito (UIO)
    GYE - UIO • Nonstop UIO - GYE • Nonstop
    $506
    $316
    per traveler
    found 1 day ago
    Casa Hotel Las Plazas

Santa Inés Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Santa Inés vacation package cost?

Offering excellent value package deals from $240 on Expedia, you'll be pleasantly surprised at how much a vacation to Santa Inés costs! Our packages simplify travel planning and maximize your savings.

What are the cheapest months to go to Santa Inés?

January, June and December are great times to look for cheap Santa Inés vacation packages. Choosing to travel in quieter periods means you can generally find better prices on hotels and flights.

How many days is enough for Santa Inés?

The ideal length for your Santa Inés vacation depends on what you'd like to do. Usually, a handful of days to a week will give you plenty of time to tick off all the leading sights and discover some hidden spots along the way.

How to find the best Santa Inés package deals?

Finding a cheap Santa Inés package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget range, add some filters and see what's available. You can personalize your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Santa Inés package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are typically lower.

Is it cheaper to book a Santa Inés vacation as a package?

An Expedia vacation package could land you considerable savings when compared to arranging flights and hotels individually. Better still, you can personalize your Santa Inés escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.

When to book a vacation package to Santa Inés?

Land incredible bargains by reserving your flights early with Expedia. If spontaneity is more your style, snap up one of our last-minute deals for an impromptu Santa Inés break.

Does Expedia offer Book Now, Pay Later Santa Inés vacation packages?

Your Santa Inés break is meant to be a relaxing escape from your daily routine, not a reason for money-related stress. So to give you a bit more flexibility, we've teamed up with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the total cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.