Santa Isabel Vacations from $527
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Your Santa Isabel Vacation
Our vacation packages to Santa Isabel give you endless opportunities to immerse yourself in new sights, sounds and sensations. And with all the details taken care of, you'll be free to enjoy your city adventure to the fullest. Make your trip to Santa Isabel even more fun and exciting by including some sightseeing. Plaza Comercial La Cachanilla, City Forest and Zoo and Juventud 2000 Sport Center are among the big attractions worth exploring. A few quick clicks is all it takes to put together the perfect Santa Isabel vacation on Expedia.
The Latest Santa Isabel vacation packages
Price found within the past 48 hours. Click for updated prices.
Laos Mar Hotel & Suites
Bella Vista
$856
per person
Nov 12 - Nov 15
found 14 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Mexicali (MXL)
8.2/10 Very Good! (1,003 reviews)
todo muy bien el personal muy amable todo bien sin duda me qedaria ahi otra vez solo un detallito necesitan modernisar las tv no puedes ver bien los canales sin antena necesitan poner cable seria todo todo lo demas exelente
Reviewed on Sep 28, 2026
Riad Xula - Boutique Hotel
El Puerto
$788
per person
Nov 12 - Nov 15
found 14 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Mexicali (MXL)
9.6/10 Exceptional! (17 reviews)
Coffee bar was confusing and parking can be a challenge. Room and property were attractive, well maintained and conveniently located. Cute hotel.
Reviewed on Sep 8, 2026
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See all available trips from Columbus to Santa Isabel
View all tripsSanta Isabel Hotel Deals
Hotel Araiza Mexicali
Blvd. Benito Juarez 2220 Mexicali BC
$112 nightly
$126 total
Sep 30 - Oct 1
Total with taxes and fees
Hotel Lucerna Mexicali
Boulevard Benito Juarez 2151 Mexicali BC
Fully refundableReserve now, pay when you stay
$104 nightly
$118 total
Oct 13 - Oct 14
Total with taxes and fees
Extended Suites Mexicali Cataviña
Calzada Manuel Gomez Morin, 886 Mexicali BC
Fully refundableReserve now, pay when you stay
$52 nightly
$62 total
Oct 18 - Oct 19
Total with taxes and fees
8/10 Very Good! (2,539 reviews)
"La h ubicación del hotel es excelente, hay varias plazas a menos de 500 metros, el estacionamiento cuenta con guardia, las habitaciones están limpias y el Personal es muy amable. Me hospedo seguido y lo recomiendo."
Reviewed on Sep 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Isabel Vacation Packages
Santa Isabel Essential Information
Language | Spanish |
|---|---|
Currency | Mexican pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | General Rodolfo Sanchez Taboada Intl. Airport (MXL) |
Population | 29,300 |
Top Sights | City Forest and Zoo, Sol Childrens Museum and Aguilas de Mexicali Stadium |
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Frequently asked questions
How much does a Santa Isabel vacation package cost?
You'll find cheap prices from $527 on Expedia for your Santa Isabel getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're hoping to snag a cheap Santa Isabel vacation package, consider visiting in January, June and December. You'll usually find lower rates on accommodations and flights during these quieter months — perfect for a budget-friendly break.
How many days is enough for Santa Isabel?
Generally, a handful of days is enough to see the main sights during your Santa Isabel vacation. However, if you prefer to have some time to relax or go on day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Start your search for a Santa Isabel package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply a few filters, like "Guest rating" and "Property type," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect Santa Isabel package deal straight away, simply tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Isabel escape underway.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll generally land a better deal than booking each component individually. And you'll still have the flexibility to create a personalized Santa Isabel vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to grab some incredible deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for traveling on a whim.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel trip is meant to be a relaxing escape from your busy life, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
