Santa Isabel Vacations

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Your Santa Isabel Vacation

Our vacation packages to Santa Isabel give you endless opportunities to immerse yourself in new sights, sounds and sensations. And with all the details taken care of, you'll be free to enjoy your city adventure to the fullest. Make your trip to Santa Isabel even more fun and exciting by including some sightseeing. Plaza Comercial La Cachanilla, City Forest and Zoo and Juventud 2000 Sport Center are among the big attractions worth exploring. A few quick clicks is all it takes to put together the perfect Santa Isabel vacation on Expedia.

Discover the most popular places to visit in Santa Isabel

Eagles Nest Stadium

4.5/5(9 reviews)

Catch an event at Eagles Nest Stadium during your trip to Mexicali. While you're here, you can savor the top-notch restaurants.

Eagles Nest Stadium

Mexicali Border Port I

After visiting Mexicali Border Port I, make a plan to see the other sights and activities in Mexicali. While in this family-friendly area, you can savor the top-notch restaurants.

Mexicali Border Port I

Plaza Comercial La Cachanilla

4.5/5(155 reviews)

You can browse for the perfect souvenirs at Plaza Comercial La Cachanilla during your trip to Mexicali. While you're here, you can savor the top-notch restaurants.

Plaza Comercial La Cachanilla

Santa Isabel Hotel Deals

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali

4 out of 5
Boulevard Benito Juarez 2151 Mexicali BC
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $102 total per night from Jan 4 to Jan 5
$102 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,431 reviews)
Good

Reviewed on Dec 7, 2025

Hotel Lucerna Mexicali
Hotel Araiza Mexicali

Hotel Araiza Mexicali

4 out of 5
Blvd. Benito Juarez 2220 Mexicali BC
Fully refundableReserve now, pay when you stay
$92 nightly
The price is $107 total per night from Dec 17 to Dec 18
$107 total
Dec 17 - Dec 18
Total with taxes and fees
8.4/10 Very Good! (1,718 reviews)
Good hotel very clean and comfortable.

Reviewed on Dec 9, 2025

Hotel Araiza Mexicali
Real Inn Mexicali

Real Inn Mexicali

4 out of 5
Avenida de Los Heroes 201 Mexicali BC
Fully refundableReserve now, pay when you stay
$76 nightly
The price is $86 total per night from Dec 24 to Dec 25
$86 total
Dec 24 - Dec 25
Total with taxes and fees
8.2/10 Very Good! (1,552 reviews)
When we arrived we were presently surprised that they had upgraded our unit to a junior executive suite. It was very roomy and in great condition and very clean. We also got a very comfortable king size bed, big screen tv with cable channels. The staff was very helpful and attentive. In the morning ...

Reviewed on Dec 8, 2025

Real Inn Mexicali
See all 71 properties in Santa Isabel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Isabel Vacation Packages

Santa Isabel Essential Information

Language
Spanish
Currency
Mexican pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
General Rodolfo Sanchez Taboada Intl. Airport (MXL)
Population
29,300
Top Sights
City Forest and Zoo, Sol Childrens Museum and Aguilas de Mexicali Stadium

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Frequently asked questions

How much does a Santa Isabel vacation package cost?
You'll find cheap prices on Expedia for your Santa Isabel getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Isabel costs.
What are the cheapest months to go to Santa Isabel?
If you're hoping to snag a cheap Santa Isabel vacation package, consider visiting in January, June and December. You'll usually find lower rates on accommodations and flights during these quieter months — perfect for a budget-friendly break.
How many days is enough for Santa Isabel?
Generally, a handful of days is enough to see the main sights during your Santa Isabel vacation. However, if you prefer to have some time to relax or go on day trips, think about extending your itinerary.
How to find the best Santa Isabel package deals?
Start your search for a Santa Isabel package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply a few filters, like "Guest rating" and "Property type," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect Santa Isabel package deal straight away, simply tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Isabel escape underway.
Is it cheaper to book a Santa Isabel vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll generally land a better deal than booking each component individually. And you'll still have the flexibility to create a personalized Santa Isabel vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Santa Isabel?
If you have your Santa Isabel vacation dates confirmed, book as soon as you can to grab some incredible deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for traveling on a whim.
Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?
Your Santa Isabel trip is meant to be a relaxing escape from your busy life, not a source of money worries. So to allow you extra flexibility, we've joined up with online lender Affirm to bring you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and split up the total cost over 3, 6 or 12 months. Plus, there aren't any late payment fees or hidden costs to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.