Find hotels in Santa Isabel from $36

Start date: Check-in selected.
To Date
End date: Check-out
  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Isabel hotels

Calafia Hotel

Calafia Hotel
3.5 star property
Eguía
8.2 out of 10, Very Good, (1002)
"The breakfast was excellent with great customer service!"
United States
Nora
$70 nightly
The price is $81
Jan 11 - Jan 12
Total with taxes and fees
Calafia Hotel

City Express by Marriott Mexicali

City Express by Marriott Mexicali
3.0 star property
Mexicali
8.2 out of 10, Very Good, (1002)
"Excellent service, clean environment, plenty of parking, breakfast was outstanding! "
United States
Martha
$72 nightly
The price is $81
Jan 6 - Jan 7
Total with taxes and fees
City Express by Marriott Mexicali

Hotel Araiza Mexicali

Hotel Araiza Mexicali
4.0 star property
Mexicali
8.6 out of 10, Excellent, (1739)
"Exellen place to stay in Mexicali"
United States
Sergio
$106 nightly
The price is $122
Jan 22 - Jan 23
Total with taxes and fees
Hotel Araiza Mexicali

Hotel Lucerna Mexicali

Hotel Lucerna Mexicali
4.0 star property
Mexicali
9.2 out of 10, Wonderful, (1446)
"Excellent breakfast, hotel, everything was above and beyond expectations. "
United States
Gabriela
$104 nightly
The price is $118
Jan 15 - Jan 16
Total with taxes and fees
Hotel Lucerna Mexicali

City Express Plus by Marriott Mexicali

City Express Plus by Marriott Mexicali
3.5 star property
Mexicali
8.6 out of 10, Excellent, (1011)
"Great service with comfort and relaxing stay. Central location. "
United States
Claudia
$74 nightly
The price is $84
Jan 4 - Jan 5
Total with taxes and fees
City Express Plus by Marriott Mexicali

Holiday Inn Express & Suites Mexicali by IHG

Holiday Inn Express & Suites Mexicali by IHG
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (1001)
"Great service, the room was really clean, decent breakfast. "
United States
Jose
$125 nightly
The price is $141
Jan 2 - Jan 3
Total with taxes and fees
Holiday Inn Express & Suites Mexicali by IHG

Courtyard by Marriott Mexicali

Courtyard by Marriott Mexicali
3.0 star property
Mexicali
9.4 out of 10, Exceptional, (828)
"Love staying here, hotel is clean, comfortable and good dinner options. The parking is good. The staff is very nice and accommodating. "
United States
Lorena
$101 nightly
The price is $114
Jan 23 - Jan 24
Total with taxes and fees
Courtyard by Marriott Mexicali

Fiesta Inn Mexicali

Fiesta Inn Mexicali
3.5 star property
Civic Center
8.4 out of 10, Very Good, (1000)
"Great customer service. Great room service. My food was very good. Shower warmed up very quickly. Quiet."
United States
Yvonne
$78 nightly
The price is $89
Jan 2 - Jan 3
Total with taxes and fees
Fiesta Inn Mexicali

Sleep Inn Mexicali

Sleep Inn Mexicali
3.0 star property
Mexicali
8.4 out of 10, Very Good, (1001)
"Friendly staff, clean rooms "
United States
Sara
$57 nightly
The price is $69
Jan 3 - Jan 4
Total with taxes and fees
Sleep Inn Mexicali

Hotel Siesta Real

Hotel Siesta Real
3.0 star property
Mexicali
8.2 out of 10, Very Good, (905)
"Easy Parking and Excellent Restaurant "
United States
ARTURO
$68 nightly
The price is $78
Jan 6 - Jan 7
Total with taxes and fees
Hotel Siesta Real

Real Inn Mexicali

Real Inn Mexicali
4.0 star property
Civic Center
8.2 out of 10, Very Good, (1572)
"Room is always clean and staff is always helpful thank you "
United States
ROBERT
$78 nightly
The price is $88
Jan 10 - Jan 11
Total with taxes and fees
Real Inn Mexicali

Extended Suites Mexicali Cataviña

Extended Suites Mexicali Cataviña
3.0 star property
Mexicali
8.0 out of 10, Very Good, (2220)
"Very nice people clean rooms all new appliances excellent service and great location will recommend to anyone looking for good rest! "
United States
JOSE
$47 nightly
The price is $57
Jan 4 - Jan 5
Total with taxes and fees
Extended Suites Mexicali Cataviña

City Express Junior by Marriott Mexicali

City Express Junior by Marriott Mexicali
3.0 star property
Mexicali
7.8 out of 10, Good, (1005)
"Exelent guest service "
United States
Kevin
$64 nightly
The price is $73
Jan 4 - Jan 5
Total with taxes and fees
City Express Junior by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali

Fairfield Inn & Suites by Marriott Mexicali
2.5 star property
Mexicali
9.6 out of 10, Exceptional, (1002)
"Breakfast was great!"
United States
Joanna
$105 nightly
The price is $119
Jan 23 - Jan 24
Total with taxes and fees
Fairfield Inn & Suites by Marriott Mexicali

One Mexicali

One Mexicali
3.0 star property
Mexicali
7.8 out of 10, Good, (1001)
"NICE PLACE"
United States
ROBERTO
$67 nightly
The price is $77
Jan 3 - Jan 4
Total with taxes and fees
One Mexicali

Hotel Misión Plaza Mexicali

Hotel Misión Plaza Mexicali
2.0 star property
La Chinesca
7.4 out of 10, Good, (51)
"We ended up leaving to a different hotel. The smell is horrible, photos dont match the rooms, and its just in bad shape"
United States
Manuel
$37 nightly
The price is $45
Jan 5 - Jan 6
Total with taxes and fees
Hotel Misión Plaza Mexicali

Motel Paraiso

Motel Paraiso
3.0 star property
Mexicali
9.0 out of 10, Wonderful, (2)
"?"
United States
EMILIO
$96 nightly
The price is $119
Jan 2 - Jan 3
Total with taxes and fees
Motel Paraiso

Hotel Cosmos Don Carlos

Hotel Cosmos Don Carlos
3.0 star property
Eguía
8.0 out of 10, Very Good, (492)
"Great stay!"
United States
Gustavo Adolfo
$51 nightly
The price is $58
Jan 2 - Jan 3
Total with taxes and fees
Hotel Cosmos Don Carlos

Motel Olimpo

Motel Olimpo
2.0 star property
Mexicali
7.0 out of 10, Good, (4)
"Nice and a clean place. "
United States
Sonia
$36 nightly
The price is $42
Jan 5 - Jan 6
Total with taxes and fees
Motel Olimpo

Hotel Colonial Mexicali

Hotel Colonial Mexicali
3.5 star property
Civic Center
8.0 out of 10, Very Good, (1007)
"Great hotel"
United States
Juan
$76 nightly
The price is $85
Jan 22 - Jan 23
Total with taxes and fees
Hotel Colonial Mexicali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Isabel Hotel Reviews

More cheap stays in Santa Isabel

Find out more about Santa Isabel

Top reasons to visit Santa Isabel

  • Outdoor Adventures: Santa Isabel is perfect for romantic escapes, offering a range of outdoor activities to enjoy the fresh air.
  • Cultural Exploration: Visit local civic centers, art venues, and museums for a deep dive into the rich culture of the area.
  • Picturesque Santa Isabel Island: Don't miss the chance to explore the beautiful Santa Isabel Island, ideal for leisurely strolls.
  • Charming Accommodations: Choose from a variety of hotels and resorts catering to all types of travelers, including LGBTQIA-friendly options.
  • Vibrant Nearby Attractions: Explore nearby cities like Old Havana, offering family-friendly activities and lively experiences.

Find great hotels near Santa Isabel

Explore the charming accommodations in Santa Isabel, Mexicali, where a variety of hotels and resorts await your arrival. Whether you're seeking a business-friendly environment or an eco-certified experience, this destination offers welcoming options for everyone, including LGBTQIA travelers. With a range of amenities and positive hotel reviews, your perfect getaway is just a search away. Discover the best hotels to make your stay memorable and fulfilling.

  • Real Inn Mexicali: Emphasizing a blend of eco-friendliness and business convenience, Real Inn Mexicali stands out with its eco-certified status. Situated 6 miles from Santa Isabel, this 3.5-star hotel is perfect for environmentally conscious travelers looking for a professional setting. The hotel features essential business amenities, including a well-equipped Business Center and multiple Meeting Rooms, catering to your corporate needs while promoting sustainability. The modern design and thoughtful services make it an ideal choice for those who value both comfort and corporate functionality.
  • Hotel Colonial Mexicali: With a welcoming atmosphere for the LGBTQIA community, Hotel Colonial Mexicali is a 3-star property located 6 miles from Santa Isabel. This hotel is not only LGBTQIA-friendly but also offers a range of business-oriented services. Guests can take advantage of the 24-hour Business Center, Conference Space, and Meeting Rooms, making it suitable for professional gatherings. The hotel's charming ambiance, paired with its commitment to inclusivity, ensures that every traveler feels at home while enjoying a productive stay.
  • Fiesta Inn Mexicali: Combining eco-friendliness with a welcoming attitude towards the LGBTQIA community, Fiesta Inn Mexicali is a 3.5-star hotel located 6 miles from Santa Isabel. This property boasts a sustainable approach, making it a great choice for eco-conscious travelers. With features such as a 24-hour Business Center, multiple Meeting Rooms, and a Conference Center, it caters well to business travelers. The modern facilities and inclusive atmosphere create a supportive environment for both leisure and work, ensuring a fulfilling experience for all guests.

Where to stay in Santa Isabel

Santa Isabel offers a charming escape for those seeking romantic outdoor adventures and entertainment. Explore the vibrant atmosphere of nearby cities like Old Havana, where family-friendly activities abound. Enjoy leisurely oceanfront strolls and indulge in the oasis of luxury that surrounds the area. Whether you’re looking for recreation or simply want to connect with friendly locals, Santa Isabel and its neighboring attractions promise an unforgettable vacation experience.

  • Mexicali: As the capital of Baja California, Mexicali is a vibrant city that serves as the gateway to Santa Isabel. Known for its diverse cultural influences, travelers flock here year-round for family-oriented experiences and business opportunities. With peaks in visitor numbers during March and from June to July, the city offers a range of attractions, including shopping malls and educational venues. Notable landmarks include the local sports facility and convention center, catering to various interests. Whether you're looking for a lively city atmosphere or engaging activities, Mexicali has something for everyone.
  • Mediterráneo: Situated about 4 miles from Santa Isabel, Mediterráneo is a dynamic neighborhood known for its cultural and entertainment offerings. With a moderate seasonal influx of visitors, particularly during June to July and September, this area is perfect for those seeking a rich urban experience. Enjoy the local venues and stadiums that host thrilling sports events and cultural festivities. The lively atmosphere and community spirit make Mediterráneo a delightful place to explore, offering a blend of entertainment and culture that appeals to all travelers.
  • Lucerna: Also located 4 miles from Santa Isabel, Lucerna is a charming neighborhood that attracts families and outdoor enthusiasts alike. With visitor numbers peaking in March, July, and November, this area boasts a mix of recreational activities and entertainment options. Explore the local parks, visit museums, or enjoy the unique blowhole attraction. Shopping enthusiasts will appreciate the nearby shopping centers and malls. Lucerna’s welcoming vibe and variety of attractions make it an ideal spot for a fun and relaxing getaway.

Things to do near Santa Isabel

Santa Isabel, located in Mexicali, Baja California, is perfect for a romantic getaway filled with outdoor adventures and authentic experiences. Enjoy the fresh air with outdoor seating options while exploring the area through various trips and activities. With its charming atmosphere and unique offerings, Santa Isabel promises an unforgettable vacation that blends relaxation and entertainment seamlessly.

Shopping

The nearest shopping mall is Plaza Comercial La Cachanilla, just 6 miles from Santa Isabel, offering a variety of entertainment and family-friendly options. If you're up for a drive, both Plaza La Gran Via and Plaza San Pedro are 10 miles away, featuring similar vibes and shopping experiences.

Recreation

Experience the energetic atmosphere at Eagles Nest Stadium, perfect for sports enthusiasts. For a more tranquil vibe, head to Juventud 2000 Sport Center, where you can unwind and rejuvenate in a variety of wellness activities and relaxation options, all within a short drive from Santa Isabel.

Adventure

In Santa Isabel, explore the stunning landscapes while hiking in the nearby Sierra de los Cucapas, offering breathtaking views and diverse wildlife. For thrill-seekers, try off-roading through the desert terrain, where you can experience exhilarating rides and picturesque sunsets that are truly unforgettable.

Nightlife

The nightlife in Santa Isabel offers a vibrant atmosphere with the nearby State Theater, just 6 miles away. Enjoy captivating performances in a cultural setting that blends romance and family-friendly entertainment, making it a perfect spot for an unforgettable night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Santa Isabel

To save money on your trip to Santa Isabel, consider visiting during the low season from August to September or December when prices drop. Sundays are the cheapest days for accommodations, while Saturdays are the priciest. Utilize Expedia to compare hotel rates and take advantage of package deals for significant savings. Look for eco-certified hotels for budget-friendly, sustainable options. Joining Expedia's One Key membership also provides exclusive discounts and the opportunity to earn cash for future stays. With these tips, you can enjoy Santa Isabel without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Santa Isabel are August to September and December, where the prices are slightly lower. This is in comparison to March and May to June, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Santa Isabel is Sunday. The most expensive day to stay in Santa Isabel is Saturday.
  • Find cheap hotels on Expedia: Utilize Expedia's search tool to refine your preferences, such as your budget, desired location, and the type of hotel you’re looking for. For instance, selecting the Eco-certified option will showcase sustainable and environmentally friendly hotels that are currently available. To find the best prices and offers, simply sort the price filter from lowest to highest.
  • Consider bundling your trip: You can enjoy significant savings by combining your hotel stay in Santa Isabel with your flights and activities through an Expedia package deal.
  • Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions near Santa Isabel

Santa Isabel in Mexicali, Baja California, offers a charming blend of romantic outdoor experiences and vibrant entertainment options. Visitors can explore local civic centers, art venues, and museums that provide rich cultural insights. Don't miss the picturesque Santa Isabel Island and consider staying at one of the best resorts in the area for a memorable getaway. Whether you're an adventurer or a culture enthusiast, Santa Isabel has something for everyone.

  • Mexicali Border Port I: This bustling civic hub serves as a gateway between the United States and Mexico, offering a unique glimpse into border culture. Visitors can observe the flow of people and goods, making it an intriguing spot for understanding cross-border dynamics.
  • State Center for the Arts (CEART): A vibrant arts center that celebrates local culture through various exhibitions and performances. It’s a wonderful place to immerse yourself in the artistic expressions of the region while enjoying its cultural vibes.
  • House of Culture: This museum showcases the rich history and traditions of Mexicali. With its cultural exhibits and engaging programs, it provides an enriching experience that highlights the local heritage.

The nearest major airports for your trip to Santa Isabel

When visiting Santa Isabel, you have a few airport options for your arrival. The closest is Mexicali, Baja California Norte (MXL-General Rodolfo Sanchez Taboada Intl.), located 19 miles away. Recommended hotels near this airport include Courtyard by Marriott Mexicali and Sleep Inn Mexicali, both about 9 miles away. Another option is Yuma, AZ (YUM-Yuma Intl.), situated 57 miles from Santa Isabel, with nearby hotels such as Radisson Hotel Yuma, offering 24-hour shuttle service. Lastly, El Centro, CA (IPL-Imperial County) is 14 miles away, with accommodations like Brawley Inn located 10 miles from the airport. Each location provides convenient access to help you start your vacation smoothly.

Frequently asked questions

Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Santa Isabel hotel for you.
How can I save on a Santa Isabel hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Santa Isabel hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Isabel hotel?
Prices for hotels in Santa Isabel often vary, but you can find a great deal from $36 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia