Santa Maria di Leuca Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Santa Maria di Leuca vacation rentals

Terrace/patio
Residence Bellevue

Residence Bellevue

Residence Bellevue
Castrignano del Capo
9.6 out of 10, Exceptional, (5)
"Appartamento ben tenuto, pulito, Wi-Fi funzionante, aria condizionata che rende l’intera casa fresca. Posto in una zona tranquilla, silenziosa, a pochi passi dall’area centrale."
Italy
Emanuela
Residence Bellevue
Exterior
VILLA FELICITA - OCCIDENTE

VILLA FELICITA - OCCIDENTE

VILLA FELICITA - OCCIDENTE
Santa Maria di Leuca
$412 nightly
The price is $453
Dec 30 - Dec 31
Total with taxes and fees
VILLA FELICITA - OCCIDENTE
Exterior
VILLA FELICITA - MERIDIANA

VILLA FELICITA - MERIDIANA

VILLA FELICITA - MERIDIANA
Santa Maria di Leuca
$412 nightly
The price is $453
Dec 30 - Dec 31
Total with taxes and fees
VILLA FELICITA - MERIDIANA
Seasonal outdoor pool
VILLA FELICITA - ORIENTE

VILLA FELICITA - ORIENTE

VILLA FELICITA - ORIENTE
Santa Maria di Leuca
$412 nightly
The price is $453
Dec 30 - Dec 31
Total with taxes and fees
VILLA FELICITA - ORIENTE
Outdoor pool, pool umbrellas, sun loungers
Panacea Residence

Panacea Residence

Panacea Residence
Santa Cesarea Terme
10.0 out of 10, Exceptional, (3)
"Super lieve mensen, spreken wel nauwelijks engels. Bio produkten, lekkere maaltijden, prachtige home made taarten"
Belgium
Anonymous traveler
Panacea Residence
Exterior
Torre Vecchia Relais

Torre Vecchia Relais

Torre Vecchia Relais
Ugento
$139 nightly
The price is $153
Dec 30 - Dec 31
Total with taxes and fees
Torre Vecchia Relais
Superior Double Room, 1 Queen Bed, Ensuite, Sea View | In-room safe, desk, cribs/infant beds, free WiFi
Villa Raffaella

Villa Raffaella

Villa Raffaella
4.0 star property
Santa Cesarea Terme
9.2 out of 10, Wonderful, (38)
"This is a very comfortable, beautiful place with a great breakfast. It’s located near the sea and thermal baths. I really enjoyed my stay!"
United States
Maurice
$113 nightly
The price is $124
Jan 8 - Jan 9, 2026
Total with taxes and fees
Villa Raffaella
Balcony
2133 Maresidence - Camere Matrimoniali

2133 Maresidence - Camere Matrimoniali

2133 Maresidence - Camere Matrimoniali
Salve
$118 nightly
The price is $130
Dec 30 - Dec 31
Total with taxes and fees
2133 Maresidence - Camere Matrimoniali
Apartment, 1 Bedroom, Balcony, Ocean View | Beach | Beach nearby
Apartment in old Building

Apartment in old Building

Apartment in old Building
Santa Cesarea Terme
10.0 out of 10, Exceptional, (1)
"Accueil attentionné. Excellent petit déjeuner. L'appartement était parfait et le personnel était très attentionné."
Canada
Mireille
$181 nightly
The price is $192
Dec 30 - Dec 31
Total with taxes and fees
Apartment in old Building
On the beach, white sand, beach umbrellas, beach towels
Villa Sea Front

Villa Sea Front

Villa Sea Front
Torre Pali
$309 nightly
The price is $340
Jan 22 - Jan 23, 2026
Total with taxes and fees
Villa Sea Front
Seasonal outdoor pool
Tenuta Cesarina

Tenuta Cesarina

Tenuta Cesarina
Alessano
$177 nightly
The price is $194
Jan 4 - Jan 5, 2026
Total with taxes and fees
Tenuta Cesarina
House | 1 bedroom
2132 Maresidence - Camere Triple

2132 Maresidence - Camere Triple

2132 Maresidence - Camere Triple
Salve
$196 nightly
The price is $219
Dec 30 - Dec 31
Total with taxes and fees
2132 Maresidence - Camere Triple
Apartment, 2 Bedrooms, Terrace, Sea View | Terrace/patio
Villa Valletta 1 & 2

Villa Valletta 1 & 2

Villa Valletta 1 & 2
Santa Cesarea Terme
$221 nightly
The price is $243
Dec 30 - Dec 31
Total with taxes and fees
Villa Valletta 1 & 2
Front of property
Residence Borgo Antico

Residence Borgo Antico

Residence Borgo Antico
Diso
7.2 out of 10, Good, (5)
"Il nostro soggiorno è stato eccezionale, la posizione è perfetta per esplorare il Salento.L'appartamento era spazioso, arieggiato e super confortevole. Il letto comodissimo e la connessione wi-fi in camere veloce e affidabile. Il relax all'interno del Borgo è assicurato. Inoltre abbiamo usufruito gratuitamente delle biciclette e abbiamo fatto passeggiate immersi tra ulivi secolari e muretti a secco. Bellissimo e rilassante. Ci torneremo e lo consigliamo vivamente."
Italy
Anonymous traveler
$193 nightly
The price is $212
Dec 30 - Dec 31
Total with taxes and fees
Residence Borgo Antico
Apartment, 1 Bedroom, Ocean View | View from property
Palazzo De Donno App 2

Palazzo De Donno App 2

Palazzo De Donno App 2
Santa Cesarea Terme
$181 nightly
The price is $192
Dec 30 - Dec 31
Total with taxes and fees
Palazzo De Donno App 2
Apartment | 1 bedroom, free WiFi
2132 Maresidence - Camere Triple

2132 Maresidence - Camere Triple

2132 Maresidence - Camere Triple
Salve
$117 nightly
The price is $131
Dec 30 - Dec 31
Total with taxes and fees
2132 Maresidence - Camere Triple
Apartment, 1 Bedroom, Patio, Garden View | View from property
Palazzo De Donno n01

Palazzo De Donno n01

Palazzo De Donno n01
Santa Cesarea Terme
$180 nightly
The price is $191
Jan 9 - Jan 10, 2026
Total with taxes and fees
Palazzo De Donno n01
Apartment, 1 Bedroom, Balcony, Ocean View | View from property
Palazzo De Donno App No04

Palazzo De Donno App No04

Palazzo De Donno App No04
Santa Cesarea Terme
$323 nightly
The price is $344
Dec 30 - Dec 31
Total with taxes and fees
Palazzo De Donno App No04
View from property
Palazzo De Donno Apartment 4

Palazzo De Donno Apartment 4

Palazzo De Donno Apartment 4
Santa Cesarea Terme
2.0 out of 10, (1)
"We never got to stay there. Expedia promised to put us there but instead booked us into a different hotel and didn’t bother letting us know. So instead of getting our sea view suite we got put into Magnolia Villa Ceseara in an underground suite. Nice place but pretty cave like. Hardly where you want to be on your 30th anniversary."
Canada
Shelley
$181 nightly
The price is $192
Dec 30 - Dec 31
Total with taxes and fees
Palazzo De Donno Apartment 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Maria di Leuca Hotel Reviews

Direct sea access and stunning location

Direct sea access and stunning location

10/10 Excellent
"Majoittaja ohjeisti hyvin, ja sisäänkirjautuminen oli sujuvaa. Talon näköala auringonlaskuihin on rannikon paras!!"
Eija V. 10-night trip
Posted 1 month ago
Direct sea access and stunning location

Find out more about Santa Maria di Leuca

Everything you need to know about Santa Maria di Leuca vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Maria di Leuca vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Maria di Leuca vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Maria di Leuca vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Maria di Leuca. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Maria di Leuca in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $124 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Maria di Leuca rentals

At Expedia, we put the best Santa Maria di Leuca vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Maria di Leuca rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Maria di Leuca vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Maria di Leuca. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Santa Maria di Leuca?

Yes, there are vacation rentals close to the most popular local attractions in Santa Maria di Leuca, or you can select a more remote option if you're looking for relaxation. Santa Maria di Leuca is known for its waterfront and monuments. Make sure you have time to check out the restaurants while you're in the area.

What's the top vacation rental that Santa Maria di Leuca has to offer?

Agriturismo La Natura: This vacation home rental outside of Santa Maria di Leuca offers a furnished patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities like a full-sized fridge and a stovetop can make your vacation run smoothly. Our travelers also rate ONLY 150 METERS FROM THE SEA OF S. SALENTO- MARIA DI LEUCA- PESCOLUSE-Torrevado as a favorite home for rent in Santa Maria di Leuca.

How many vacation rentals are there in Santa Maria di Leuca?

Choose from 61 Expedia vacation rentals in Santa Maria di Leuca for a memorable vacation.

What’s there to see and do in Santa Maria di Leuca?

Santa Maria di Leuca Beach and Ionian Sea are a couple of lovely local spots to get outside and enjoy nature. Basilica Santuario Santa Maria De Finibus Terrae and Lighthouse of Santa Maria di Leuca are other places to visit while you're in town.

What’s a vacation rental in Santa Maria di Leuca like?

Vacation rentals are private properties where you can stay for a few weeks or just a few days in Santa Maria di Leuca. Vacation rentals feature amenities such as kitchens and laundry facilities so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of security away from public hotel elevators and busy front desks while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for family gatherings.