Santa Maria in Montesanto contributes greatly to the social and religious ways of this place. It's a nice place to enjoy a moment of contemplation during a busy travel itinerary.
You're spoiled for sightseeing choice when in Rome City Centre. Santa Maria in Montesanto is a good place to start here, but there are many other interesting spots to enjoy. St. Peter's Basilica, Roman Forum, and Piazza Navona are near the house of prayer and will fill in your day nicely.