Santa María Vacations from $1,170
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Your Santa María Vacation
When you book a Santa María vacation package, you can kick back and enjoy your escape to the fullest. Uncover the highlights of this fascinating city knowing that all the travel planning has been looked after before you go. San Jose Beach and Plaza de Armas are a couple of the must-see sights to visit during a trip to Santa María. No matter your travel plans or the size of your budget, putting together a tailored Santa María vacation is a breeze with Expedia.
The Latest Santa María vacation packages
Price found within the past 48 hours. Click for updated prices.
Divina Tower
Recoleta
$1,195
per person
Dec 9 - Dec 14
found 14 hours ago
Roundtrip non-stop flight included
New York (NYC) to Asuncion (ASU)
9.4/10 Exceptional! (40 reviews)
Muy buena ubicacion,limpio,moderno,agradable,muy buena atencion del personal ayudan y crean una atmosfera agradable,muchas gracias
Reviewed on Oct 8, 2026
Granados Park Hotel
La Encarnacion
$1,241
per person
Dec 9 - Dec 14
found 14 hours ago
Roundtrip non-stop flight included
New York (NYC) to Asuncion (ASU)
8.8/10 Excellent! (238 reviews)
Prior communication poor as did not reply to 6 messages before arrival. They did allow us to check in early though.Out toilet leaked all night so kept us awake. Breakfast was ok but bread and cake items were often hard and old. Staff would wrap them up after every breakfast for next day. Had a couple of meals at restaurant which were very good.
Reviewed on Oct 7, 2026
Don't see what you're looking for?
See all available trips from Columbus to Santa María
View all tripsSanta María Hotel Deals
Sun Hotel
Encarnacion Itapúa
$58 nightly
$64 total
Oct 15 - Oct 16
Total with taxes and fees
Awa Resort Hotel
Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion
Fully refundableReserve now, pay when you stay
$92 nightly
$101 total
Oct 29 - Oct 30
Total with taxes and fees
Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Fully refundableReserve now, pay when you stay
$68 nightly
$74 total
Oct 18 - Oct 19
Total with taxes and fees
9.4/10 Exceptional! (213 reviews)
"The best thing of the property was the Staff. They were accommodating and always asking you. How was your day very very friendly."
Reviewed on Sep 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa María Vacation Packages
Santa Marían Essential Information
Language | Spanish |
|---|---|
Currency | Paraguayan guaranís |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Libertador General Jose de San Martin Airport (PSS) |
Top Sights | San Jose Beach and Plaza de Armas |
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Frequently asked questions
How much does a Santa María vacation package cost?
Offering great value package deals from $1,170 on Expedia, you'll be pleasantly surprised at how much a vacation to Santa María costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Santa María?
You can typically find lower rates and better availability in February, March and August. Take a look at our cheap Santa María vacation packages and you could land some great off-season discounts.
How many days is enough for Santa María?
With a well-organized schedule, you can easily tick off the top Santa Marían attractions in a handful of days. But if you want to discover lesser-known spots or take day trips, think about booking your Santa María vacation for longer.
How to find the best Santa María package deals?
Use Expedia's handy filters to find some fabulous Santa María package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-peak season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to lock in your vacation package well in advance.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could save you hundreds of dollars when compared to booking hotels and flights separately. Better still, you can customize your Santa Marían escape to fit your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
When to book a vacation package to Santa María?
If you have your Santa María vacation dates locked in, book as early as you can to snap up some terrific deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are great for setting off on a whim.
Does Expedia offer Book Now, Pay Later Santa María vacation packages?
If you're anything like us, you love traveling the world but are not a fan of the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the total cost of your Santa María vacation across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
