Santa Maria Vacations from $485

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Santa Maria vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel los Españoles Plus

Hotel los Españoles Plus

3.5 out of 5
Providencia
Price was $637, price is now $485 per person
$485
per person
Mar 12 - Mar 15
found 18 hours ago
Roundtrip flight included
Lima (LIM) to Santiago (SCL)
9.2/10 Wonderful! (95 reviews)
Muy buena opción de hospedaje, amabilidad en el personal, excelente servicio.

Reviewed on Dec 29, 2025

W Santiago

W Santiago

5 out of 5
Las Condes
Price was $1,193, price is now $661 per person
$661
per person
Mar 12 - Mar 15
found 18 hours ago
Roundtrip flight included
Lima (LIM) to Santiago (SCL)
8.8/10 Excellent! (513 reviews)
New Year’s Eve has a good rooftop party

Reviewed on Jan 14, 2026

Hotel Eco Boutique Bidasoa

Hotel Eco Boutique Bidasoa

4 out of 5
Vitacura
Price was $856, price is now $519 per person
$519
per person
Mar 12 - Mar 15
found 18 hours ago
Roundtrip flight included
Lima (LIM) to Santiago (SCL)
9.2/10 Wonderful! (240 reviews)
Everyone at this hotel

Reviewed on Jan 17, 2026

Mandarin Oriental, Santiago

Mandarin Oriental, Santiago

5 out of 5
Las Condes
Price was $1,017, price is now $696 per person
$696
per person
Mar 12 - Mar 15
found 18 hours ago
Roundtrip flight included
Lima (LIM) to Santiago (SCL)
9.2/10 Wonderful! (922 reviews)
The staff were all so lovely & helpful. The room was amazing on the 16th floor & the house keeping was so efficient, The breakfast was one of the best breakfasts we have had at any hotel. Definitely 5 stars.

Reviewed on Jan 19, 2026

Aubrey Hotel Boutique

Aubrey Hotel Boutique

3.5 out of 5
Bellavista
Price was $1,018, price is now $789 per person
$789
per person
Mar 12 - Mar 15
found 18 hours ago
Roundtrip flight included
Lima (LIM) to Santiago (SCL)
9.4/10 Exceptional! (132 reviews)
This hotel provided an incredible stay in Santiago. The room was spacious, yet cozy. The shared spaces, including the pool, were clean and never too busy. The breakfast really stood out with so many options to eat and drink. Highly recommend!

Reviewed on Jan 19, 2026

Don't see what you're looking for?
See all available trips from Columbus to Santa Maria
View all trips

Discover the most popular places to visit in Santa Maria

El Zaino Dreaming Stones

You can find out about the history of Santa Maria with a stop at El Zaino Dreaming Stones.

El Zaino Dreaming Stones

What to do in Santa Maria

Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic

Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic

$75
per adult
Tour 1 Day Portillo and Lagoon of the Inca from Santiago Picnic
Full Day Portillo Ski Center, Wine and Empanada Tour

Portillo Inca Lagoon in Los Andes + Local Vineyard Tour

$225
per adult
Portillo Inca Lagoon in Los Andes + Local Vineyard Tour
See all activities in Santa Maria

Santa Maria Hotel Deals

Termas Jahuel Hotel & Spa

Termas Jahuel Hotel & Spa

3.5 out of 5
Jahuel s/n - San Felipe Santa Maria Valparaiso
Estadía de Lujo
Excelente servicio, maravilloso lugar para desconectarse de la ciudad, los tratamientos del spa realmente espectaculares, la comida buenísima, realmente un servicio de lujo.

Reviewed on Mar 31, 2021

Get rates
Termas Jahuel Hotel & Spa
Termas el Corazon

Termas el Corazon

3 out of 5
Doctor Antonio Bianchini 2156 Los Andes Región de Valparaíso
Fully refundableReserve now, pay when you stay
$299 nightly
The price is $299 total per night from Jan 26 to Jan 27
$299 total
Jan 26 - Jan 27
7.2/10 Good! (10 reviews)
Relajo cerca de Santiago
Fue una muy buena experiencia, todo en el hotel bien cuidado y pensado para pasar unos buenos días de relajo. ¡Súper recomendado!

Reviewed on Mar 2, 2020

Termas el Corazon
Hotel Genova

Hotel Genova

2.5 out of 5
523 Las Heras Los Andes Región de Valparaíso
Fully refundableReserve now, pay when you stay
7.2/10 Good! (41 reviews)
Not good
You get what you pay for! :(

Reviewed on Mar 24, 2024

Get rates
Hotel Genova
See all 23 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria Vacation Packages

Santa Maria Essential Information

Language
Spanish
Currency
Chilean pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Max Temp Winter
50ºF
Max Temp Summer
75ºF
Top Sights
Vina Errazuriz and Vina Von Siebenthal

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santa Maria vacation package cost?
You can snap up a vacation package to this destination from $485 on Expedia. But how much your vacation to Santa Maria costs will depend on factors like the season, hotel choice and length of stay.
What are the cheapest months to go to Santa Maria?
December, January and February are the best times to search for cheap Santa Maria vacation packages. Traveling in quieter periods means you'll typically find reduced prices on flights and hotels.
How many days is enough for Santa Maria?
Usually, a handful of days is enough to see the major attractions during your Santa Maria vacation. However, if you prefer to have some time to chill out or go on day trips, think about extending your itinerary.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply a few filters, like "Popular locations" and "Property type," to tailor the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Santa Maria package deal right away, just tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Santa Maria vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santa Maria?
If you have your Santa Maria vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Santa Maria?

  1. Choose when to go: Check your diary and get packing. Your favorite season and the activities on offer will also help you decide when to visit Santa Maria.
  2. Work out your budget: Ensure you have enough money to cover everything from meals and transportation to flights and activities. Your accommodations will probably be the biggest expense during your trip to Santa Maria.
  3. Use our trip planning tool to discover Santa Maria: Research every part of your trip to Santa Maria with this comprehensive planner. Invite your family and friends to collaborate on a group getaway, search for stays or things to do and make bookings.
  4. Set the duration of your trip: Start by compiling a list of the attractions and activities you want to get to in Santa Maria. Then, estimate how long you'll need at each, including any travel time.
  5. Bundle your bookings: With your travel dates in order, you can combine your car rental, flights, hotels and more into a customized Santa Maria vacation package.
  6. Book any excursions or activities: Now to the fun part — locking in everything you want to do and see. Browse some of the exciting things to do in Santa Maria and book your tickets early to save time (and maybe some cash too!).

Does Expedia offer Book Now, Pay Later Santa Maria vacation packages?
Your Santa Maria break should be a relaxing escape from your busy life, not a reason for money worries. So to give you a little more flexibility, we've partnered with online lender Affirm to bring you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.