Title: Top Design Hotels in Santa Palomba from $409 - Expedia.com [Santa Palomba Travel Guide](https://expedia.com/Santa-Palomba.dx6229175)[Hotels in Santa Palomba](https://expedia.com/Santa-Palomba-Hotels.d6229175.Travel-Guide-Hotels)[Vacation Rentals in Santa Palomba](https://expedia.com/Santa-Palomba-Vacation-Rentals.d6229175.Travel-Guide-VacationRentals)[Flights to Santa Palomba](https://expedia.com/Cheap-Flights-To-Santa-Palomba.d6229175.Travel-Guide-Flights)[Car Rentals in Santa Palomba](https://expedia.com/Car-Rentals-In-Santa-Palomba.d6229175.Car-Rental-Guide)[Santa Palomba Vacation Packages](https://expedia.com/Santa-Palomba.d6229175.Destination-Travel-Guides) ![Lodging Image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/lodging.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=6229175&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=6229175&startDate=2026-03-31&endDate=2026-04-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6229175&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6229175&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Palomba Design Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/88000000/87680000/87679000/87678971/9bde7d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/88000000/87680000/87679000/87678971/4d047c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden view](https://images.trvl-media.com/lodging/88000000/87680000/87679000/87678971/12a21e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite, City View | City view](https://images.trvl-media.com/lodging/88000000/87680000/87679000/87678971/6808e140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palazzo Velabro, a Member of Design Hotels [](https://www.expedia.com/Rome-Hotels-Palazzo-Velabro.h87678971.Hotel-Information) Rome City Centre 9.8/10 Exceptional (70 reviews) "Absolutely perfect location and hotel was very clean and staff exceptional!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) TIMOTHY $356 nightly $409 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/Rome-Hotels-Palazzo-Velabro.h87678971.Hotel-Information) ![City view from property](https://images.trvl-media.com/lodging/10000000/9780000/9777300/9777298/d735c10c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/10000000/9780000/9777300/9777298/b661061c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9780000/9777300/9777298/eec5b4cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily continental breakfast (EUR 25 per person)](https://images.trvl-media.com/lodging/10000000/9780000/9777300/9777298/aeaf27c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### G-Rough, Rome, a Member of Design Hotels [](https://www.expedia.com/Rome-Hotels-G-Rough.h9777298.Hotel-Information) Rome City Centre 9.6/10 Exceptional (71 reviews) "What an arty, uber creative place! Fabulous clash of old historic and mid mod vibe. Great staff and the location couldn’t be better. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) ELIZABETH [](https://www.expedia.com/Rome-Hotels-G-Rough.h9777298.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-12&endDate=2026-04-13®ionId=6229175&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Palomba-Hotels-Design-Hotels.0-0-d6229175--bDesignHotels.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Palomba-Hotels-Design-Hotels.0-0-d6229175--bDesignHotels.Travel-Guide-Filter-Hotels) ## Top Santa Palomba Hotel Reviews ![Hotel Quirinale](https://images.trvl-media.com/lodging/1000000/10000/1100/1058/1c2ed679_y.jpg) ### Hotel Quirinale 8/10 Good "Breakfast was great. Unfortunately both taxis they ordered for us after we clarifed where we were going they took us to the wrong destinations. Not sure who made the errors. Would stay there again location was great. We had to ask them for our VIP access discount. We also never were offered a room upgrade...they were not forthcoming with the information about these" [](https://expedia.com/Rome-Hotels-Hotel-Quirinale.h1058.Hotel-Information) ![Fabulous Village](https://images.trvl-media.com/lodging/5000000/4170000/4163300/4163290/c4412019_y.jpg) ### Fabulous Village 10/10 Excellent "It was march so the weather was cold at night and the heating system was good so we were warm" [](https://expedia.com/Rome-Hotels-Fabulous-Village.h4163290.Hotel-Information) ![The Guardian Hotel](https://images.trvl-media.com/lodging/16000000/15640000/15634200/15634169/2070cef3_y.jpg) ### The Guardian Hotel 10/10 Excellent "Our stay at the The Guardian Hotel was nothing short of exceptional. From the moment we arrived, everything was handled with professionalism and warmth, setting the tone for a truly enjoyable visit. The hotel itself is beautifully presented, with a high standard of cleanliness throughout—every area felt fresh, well-maintained, and cared for. The rooms were comfortable and thoughtfully prepared, providing the perfect place to relax after a day exploring the city. The food was equally impressive, offering both quality and variety, with everything we tried prepared to a high standard. Service across the hotel was consistently excellent—attentive without being intrusive, and always delivered with a friendly, welcoming approach. The location is another standout feature, ideally placed for exploring Rome, with many key attractions easily accessible, making it a perfect base for both first-time visitors and returning travellers. Overall, an outstanding stay—highly recommended and one we would gladly repeat." [](https://expedia.com/Rome-Hotels-The-Guardian-Hotel.h15634169.Hotel-Information) ![Hotel Artemide](https://images.trvl-media.com/lodging/1000000/50000/45900/45856/dccbfa6d_y.jpg) ### Hotel Artemide 2/10 Terrible "Worst experience ever. Two pairs of my Gucci footwear brand new black heels and brown shoes — were stolen from my room. The hotel showed no accountability and failed to help. When I asked to check CCTV, they refused and told me to get a police report first. The police station was closed and we had a flight the next day, so it wasn’t possible. Very disappointing and stressful. Would not recommend." [](https://expedia.com/Rome-Hotels-Hotel-Artemide.h45856.Hotel-Information) ![Trastevere Roma | UNA Esperienze](https://images.trvl-media.com/lodging/75000000/74060000/74055900/74055827/932fd053_y.jpg) ### Trastevere Roma | UNA Esperienze 10/10 Excellent "Great breakfast. Excellent location near many restaurants. Highly walkable location" [](https://expedia.com/Rome-Hotels-UNAHOTELS-Trastevere-Roma.h74055827.Hotel-Information) ![The Hive Hotel](https://images.trvl-media.com/lodging/25000000/24470000/24463300/24463268/ec6c185a_y.jpg) ### The Hive Hotel 10/10 Excellent "Everything was perfect!!" [](https://expedia.com/Rome-Hotels-The-Hive-Hotel.h24463268.Hotel-Information) ![The Social Hub Rome](https://images.trvl-media.com/lodging/110000000/109580000/109577000/109576916/348f9b05_y.jpg) ### The Social Hub Rome 10/10 Excellent "It was an amazing experience in this Hotel “the social Hub” The staff was so helpful, Nicola was extremely professional and very knowledgeable. I will recomen this site in the heart beat " [](https://expedia.com/Rome-Hotels-The-Social-Hub-Rome.h109576916.Hotel-Information) ![UNA Hotels Decò Roma](https://images.trvl-media.com/lodging/3000000/2230000/2222500/2222425/f97ca989_y.jpg) ### UNA Hotels Decò Roma 10/10 Excellent "Great, clean and conveniently located hotel very close to the centre of the city" [](https://expedia.com/Rome-Hotels-UNAHOTELS-Deco-Roma.h2222425.Hotel-Information) ![Hotel Nazionale](https://images.trvl-media.com/lodging/1000000/30000/26800/26756/f62b396f_y.jpg) ### Hotel Nazionale 10/10 Excellent "Great view, got upgraded to a suite. Very spacious, clean, and quiet room. Buffet breakfast with a lot of options. Love the cockatiels at the bar. " [](https://expedia.com/Rome-Hotels-Hotel-Nazionale.h26756.Hotel-Information) ## Explore a world of travel with Expedia - More ways to book - [Book Design Hotels in Santa Palomba on Expedia.it ](https://www.expedia.it/Santa-Palomba-Hotel-Design-Hotels.0-0-d6229175--bDesignHotels.Guida-Viaggi-Filtro-Hotel)