A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

Find hotels in Santana from $45

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 20 - Aug 21
Tomorrow
Aug 21 - Aug 22
This weekend
Aug 21 - Aug 23
Next weekend
Aug 28 - Aug 30

Filter by

Star rating

Guest rating

Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
Santana
Germany
Daniel
$202 nightly
$232 total
Aug 25 - Aug 26
Total with taxes and fees
Roça Santo António Ecolodge Hotel

2. Residencial Aeroporto

Residencial Aeroporto
São Tomé
$53 nightly
$61 total
Sep 1 - Sep 2
Total with taxes and fees
Residencial Aeroporto
A modern living room with a large window, a sofa, a coffee table, and a TV.
A modern kitchen with dark tiles, a dining area with a glass table, and a large window offering a view of greenery.
A breakfast setting with a plate of toast, ham, and eggs, a glass of orange juice, and a small dish of fruit.
A modern living room with a grey sofa, a glass coffee table, and a TV stand.

3. Hotel Kenito

Hotel Kenito
São Tomé
United States
Ada
$68 nightly
$80 total
Aug 24 - Aug 25
Total with taxes and fees
Hotel Kenito
A wooden covered porch with a railing, potted plants, and outdoor furniture.
A room with a bed, two bedside tables, a hanging light fixture, and a window with curtains.
A wooden interior with a painting of a sunset, a wooden table, and a plant.
A dining table set with plates, glasses, and cutlery, surrounded by wooden chairs.

4. Welfare Agroturismo

Welfare Agroturismo
Trindade
$74 nightly
$85 total
Sep 16 - Sep 17
Total with taxes and fees
Welfare Agroturismo
A pool with clear water reflecting palm trees and a building with outdoor seating.
A buffet spread with various dishes and drinks, surrounded by decorative plants and a central pillar.
An aerial view of a resort with multiple bungalow-style buildings, a tennis court, and a swimming pool surrounded by palm trees.
A double bed with white bedding and black and white patterned pillows, positioned against a brick wall.

5. Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
São Tomé
United Kingdom
Kysha
$176 nightly
$206 total
Aug 29 - Aug 30
Total with taxes and fees
Omali São Tomé – Principe Collection
A buffet table with various food items including fruits, pastries, and desserts.
Two men in a professional setting, one using a computer and the other on a phone.
A hotel room with two beds, a bathroom, and a green-framed mirror.
A reception area with a glass-top table, a patterned rug, and a door leading to a restaurant.

6. SH Boutique Hotel

SH Boutique Hotel
São Tomé
United States
Simon Peter
$59 nightly
$68 total
Sep 4 - Sep 5
Total with taxes and fees
SH Boutique Hotel
A wooden house with a staircase leading to a balcony, surrounded by trees.
A wooden interior with a dining table, chairs, and a kitchen area.
A wooden interior with a sofa, TV, and dining area.
A lush garden with banana trees, a wooden fence, and a small building with a green roof.

7. Guest House Quinta Natural

Guest House Quinta Natural
Trindade
$51 nightly
$58 total
Sep 16 - Sep 17
Total with taxes and fees
Guest House Quinta Natural
A reception area with a wooden slat wall, woven wall hangings, a sofa, a reception desk, and two hanging pendant lights.
A swimming pool with a water feature, lounge chairs, and a palm tree in the background.
A covered outdoor seating area with wicker furniture, a refrigerator, and a staircase in the background.
A bedroom with a wooden headboard, two white pillows, a brown bedspread, and two bedside tables.

8. Agua Leve

Agua Leve
São Tomé
$50 nightly
$57 total
Sep 1 - Sep 2
Total with taxes and fees
Agua Leve
A beach view with palm trees, a small structure, and a road leading to the beach.
A living room with a stone wall, a green sofa, a coffee table, a wicker chair, and a bookshelf filled with books.
A bar setting with a bartender preparing drinks, a man in a Jack & Jones t-shirt, and various bar tools and bottles.
A swimming pool with a pink flamingo float, surrounded by lush greenery and palm trees.

9. Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
Vila Maria
$133 nightly
$156 total
Sep 16 - Sep 17
Total with taxes and fees
Emoyeni Gardens Hotel
A cafe with orange chairs and tables, a counter with a display case, and a TV mounted on the wall.
A room with a wooden ceiling, a row of frosted windows, and two chairs.
A building with a sign reading "Central Pastelaria - Central Restaurante - Reserva C/ Descarga".
A hallway with a wooden staircase, a framed painting, and a vase with flowers.

10. Hotel Central

Hotel Central
São Tomé
Ireland
Mohammad
$48 nightly
$55 total
Sep 19 - Sep 20
Total with taxes and fees
Hotel Central

11. Hotel Vitória

Hotel Vitória
São Tomé
United Kingdom
Anonymous traveler
$60 nightly
$69 total
Aug 21 - Aug 22
Total with taxes and fees
Hotel Vitória

12. Miramar São Tomé

Miramar São Tomé
São Tomé
United States
sandra
$173 nightly
$198 total
Aug 22 - Aug 23
Total with taxes and fees
Miramar São Tomé

13. Residêncial Tamarindos

Residêncial Tamarindos
Guadalupe
United Kingdom
Maria
$44 nightly
$51 total
Sep 1 - Sep 2
Total with taxes and fees
Residêncial Tamarindos
A modern living room with a black sofa, a round coffee table, and a dining area with a white table and black chairs.
A bedroom with a bed, a wardrobe, and a nightstand.
A living room with a blue sofa, a white coffee table with a remote control, a flat-screen TV, and a dining area with a table and chairs.

14. Nour Apartments

Nour Apartments
São Tomé
$47 nightly
$55 total
Sep 1 - Sep 2
Total with taxes and fees
Nour Apartments
A swimming pool with a gazebo, palm trees, and a building in the background.
A spacious dining area with a round table and chairs, large windows, and a wooden ceiling.
A living room with a sofa, a coffee table, and a red rug. There is a door leading to an outdoor area with a table and chairs.
A hotel room with a large bed, a bedside table, a chair, a wardrobe, and a painting on the wall.

15. Hotel Praia

Hotel Praia
São Tomé
United States
Jonathan
$143 nightly
$164 total
Aug 21 - Aug 22
Total with taxes and fees
Hotel Praia
A swimming pool with a wooden deck and a gazebo, surrounded by palm trees and a clear sky.
A neatly made bed with a wooden headboard, a bedside lamp, and a nightstand with a phone.
A wooden deck with a view of a swimming pool and palm trees.
A white building with a covered porch, a stone pathway, and a small garden.

16. Praia Accommodation

Praia Accommodation
São Tomé
United States
Daniel
$114 nightly
$132 total
Aug 23 - Aug 24
Total with taxes and fees
Praia Accommodation
A lush garden with a variety of trees and plants, including a prominent red-leafed plant.
A dining area with a wooden table, chairs, a decorative centerpiece, a coffee machine, and a painting on the wall.
A building with a flat roof, a balcony, and a window with shutters.
A bedroom with a bed, a nightstand, and a window with shutters.

17. Casa de Ferias

Casa de Ferias
São Tomé
Sweden
Lars Roland
$63 nightly
$73 total
Sep 18 - Sep 19
Total with taxes and fees
Casa de Ferias
A wooden deck with a table and two chairs, overlooking a scenic view of the ocean and lush greenery.
A wooden cabin room with a bed, a wooden bench, and a small table with a lamp.
A rustic cabin with a stone exterior, wooden window shutters, and a red metal roof.
A wooden cabin with a metal roof, surrounded by lush greenery and flowering plants.

18. Mucumbli Hotel

Mucumbli Hotel
Neves
Norway
Morten
$121 nightly
$142 total
Aug 26 - Aug 27
Total with taxes and fees
Mucumbli Hotel
A window with a view of a lush garden and a distant body of water.
A natural landscape with a prominent rock formation in the background, surrounded by dense tropical vegetation.
A room with a bed, a table, chairs, and a view of the outdoors.
A sign with icons indicating a hotel, beach, camping, bar, waterfall, and Wi-Fi.

19. CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE
Malanza
United Kingdom
John
$41 nightly
$48 total
Aug 21 - Aug 22
Total with taxes and fees
CAMPISMO PRAIA GRANDE
A modern hotel room with a large bed, a chair, and a ceiling light.
A modern building exterior at night with a glass elevator, metal railings, and a marble floor.
A swimming pool with a tiled deck, surrounded by lounge chairs and palm trees.
A modern building with a glass railing and a marble floor.

20. Alojamento Santos Silva

Alojamento Santos Silva
São Tomé
$317 nightly
$365 total
Aug 21 - Aug 22
Total with taxes and fees
Alojamento Santos Silva
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santana

Venture to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana
A wooden bench overlooking a calm sea with a small island in the distance and lush greenery on the right.
Photo by Fabrice Récalt

Top Santana Hotel Reviews

More cheap stays in Santana

Nour Apartments

Nour Apartments

Rua 3 de Fevereiro São Tomé
$47 nightly
$55 total
Sep 1 - Sep 2
Total with taxes and fees
Nour Apartments
Hotel Kenito

Hotel Kenito

Campo de Milho São Tomé
$68 nightly
$80 total
Aug 24 - Aug 25
Total with taxes and fees
Hotel Kenito
Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza
$93 nightly
$107 total
Sep 13 - Sep 14
Total with taxes and fees
8.8/10 Excellent! (27 reviews)
Praia Inhame Eco-Lodge
Sweet Guest House

Sweet Guest House

Vila Dolores n. 087 São Tomé
Get ratesSweet Guest House
Inviting 10 Bed Apartment in Sao Tome

Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé
Get ratesInviting 10 Bed Apartment in Sao Tome
Pousada Roça São João dos Angolares

Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome
Get ratesPousada Roça São João dos Angolares

Frequently asked questions

What is the best area to stay in Santana?
The best area to stay in Santana is along the scenic coastal road that connects Santana to other parts of São Tomé and Príncipe.This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.
When is the best time to go to Santana?
The best time to go to Santana is during the dry season, which runs from June to September. This period offers the most pleasant weather for exploring the island.During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santana.
How much is the nightly rate at a Santana hotel?
Prices for hotels in Santana often vary, but you can find a great deal from $45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia