A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

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Sep 25 - Sep 26
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Sep 26 - Sep 27
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Sep 25 - Sep 27
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Oct 2 - Oct 4

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Our top choices for Santana hotels

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
Santana
Germany
Daniel
$181 nightly
$209 total
Oct 25 - Oct 26
Total with taxes and fees
Roça Santo António Ecolodge Hotel
A modern living room with a large window, a sofa, a coffee table, and a TV.
A modern living room with a grey sofa, a glass coffee table, and a TV stand.
A corridor with wooden benches and a pool area visible to the left.
A modern kitchen with dark tiles, a dining area with a glass table, and a large window offering a view of greenery.

2. Hotel Kenito

Hotel Kenito
São Tomé
United States
Ada
$67 nightly
$78 total
Oct 4 - Oct 5
Total with taxes and fees
Hotel Kenito
A pool with clear water reflecting palm trees and a building with outdoor seating.
A buffet spread with various dishes and drinks, surrounded by decorative plants and a central pillar.
A bar area with a bartender, bar counter, stools, and a view of the outdoor seating area.
An aerial view of a resort with multiple bungalow-style buildings, a tennis court, and a swimming pool surrounded by palm trees.

3. Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
São Tomé
United Kingdom
Kysha
$180 nightly
$210 total
Sep 30 - Oct 1
Total with taxes and fees
Omali São Tomé – Principe Collection
A buffet table with various food items including fruits, pastries, and desserts.
A hotel room with two beds, a bathroom, and a green-framed mirror.
A patio area with wicker furniture, a small table, and a potted plant.
A reception area with a glass-top table, a patterned rug, and a door leading to a restaurant.

4. SH Boutique Hotel

SH Boutique Hotel
São Tomé
United States
Simon Peter
$58 nightly
$67 total
Sep 27 - Sep 28
Total with taxes and fees
SH Boutique Hotel
A wooden covered porch with a railing, potted plants, and outdoor furniture.
A wooden interior with a painting of a sunset, a wooden table, and a plant.
A dining table set with plates, glasses, and cutlery, surrounded by wooden chairs.
A room with a bed, two bedside tables, a hanging light fixture, and a window with curtains.

5. Welfare Agroturismo

Welfare Agroturismo
Trindade
$64 nightly
$76 total
Oct 14 - Oct 15
Total with taxes and fees
Welfare Agroturismo
A cafe with orange chairs and tables, a counter with a display case, and a TV mounted on the wall.
A hotel room with two beds, each with white linens and towels with 'H' monograms. There is a wooden headboard, a nightstand with a lamp, and a mirror on the wall.
A room with a wooden ceiling, a row of frosted windows, and two chairs.
A hallway with a wooden staircase, a framed painting, and a vase with flowers.

6. Hotel Central

Hotel Central
São Tomé
United States
Adam
$47 nightly
$55 total
Oct 19 - Oct 20
Total with taxes and fees
Hotel Central
A reception area with a wooden slat wall, woven wall hangings, a sofa, a reception desk, and two hanging pendant lights.
A covered outdoor area with wooden planters, a tiled floor, and a person standing.
A swimming pool with a water feature, lounge chairs, and a palm tree in the background.
A covered outdoor seating area with wicker furniture, a refrigerator, and a staircase in the background.

7. Agua Leve

Agua Leve
São Tomé
$42 nightly
$49 total
Oct 10 - Oct 11
Total with taxes and fees
Agua Leve
A beach view with palm trees, a small structure, and a road leading to the beach.
A bar setting with a bartender preparing drinks, a man in a Jack & Jones t-shirt, and various bar tools and bottles.
A living room with a stone wall, a green sofa, a coffee table, a wicker chair, and a bookshelf filled with books.
A lush garden with various palm trees and tropical plants.

8. Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
Vila Maria
$138 nightly
$160 total
Sep 30 - Oct 1
Total with taxes and fees
Emoyeni Gardens Hotel

9. Hotel Vitória

Hotel Vitória
São Tomé
United Kingdom
Anonymous traveler
$50 nightly
$59 total
Oct 26 - Oct 27
Total with taxes and fees
Hotel Vitória
A wooden house with a staircase leading to a balcony, surrounded by trees.
A wooden interior with a dining table, chairs, and a kitchen area.
A wooden interior with a sofa, TV, and dining area.
A red building with a stone foundation, a covered outdoor seating area, and a large tree with broad leaves.

10. Guest House Quinta Natural

Guest House Quinta Natural
Trindade
$47 nightly
$55 total
Oct 8 - Oct 9
Total with taxes and fees
Guest House Quinta Natural
A lush garden with a variety of trees and plants, including a prominent red-leafed plant.
A bedroom with a bed, a nightstand, and a window with shutters.
A room with a wooden cabinet, a coffee machine, a plant, and a painting on the wall.
A building with a flat roof, a balcony, and a window with shutters.

11. Casa de Ferias

Casa de Ferias
São Tomé
Sweden
Lars Roland
$60 nightly
$69 total
Oct 26 - Oct 27
Total with taxes and fees
Casa de Ferias
A residential building with a tiled roof, a large window, and a sign indicating it is an airport residential property.
A single bed with a white sheet and two pillows, a wooden nightstand with a phone, and a wooden floor.
Two single beds with wooden headboards and nightstands, each with a lamp and a telephone.
A bathroom with a glass-enclosed shower, a toilet, and a sink with a mirror.

12. Residencial Aeroporto

Residencial Aeroporto
São Tomé
$54 nightly
$64 total
Oct 26 - Oct 27
Total with taxes and fees
Residencial Aeroporto
A hotel lobby with a seating area, a bar, and a piano.
A hotel room with a dining area, a sofa set, and a wall with framed artwork.
A conference room with rows of chairs facing a stage, a podium, and flags.

13. Pestana São Tomé

Pestana São Tomé
Vila Maria
Canada
alexander
$243 nightly
$280 total
Oct 26 - Oct 27
Total with taxes and fees
Pestana São Tomé
A bedroom with a bed, bedside tables, a wardrobe, and a window with curtains.
A kitchen with wooden cabinets, a marble countertop, and a dining area with a table and chairs.
A living room with two leather sofas, a coffee table with a red flower, a television, and a sliding glass door leading to an outdoor area.
A swimming pool with lounge chairs and palm trees.

14. Refúgio da Ilha

Refúgio da Ilha
Conde
$47 nightly
$54 total
Sep 26 - Sep 27
Total with taxes and fees
Refúgio da Ilha
A modern hotel room with a large bed, bedside lamps, and a ceiling air conditioner.
A poolside area with lounge chairs, a pool, and umbrellas.
A glass of orange beverage with a lime wedge and straw on a table with a view of a beach and palm trees.
A glass-enclosed shower area with a tiled floor and a view of the outside through a window.

15. Roulotte Beach São Tomé

Roulotte Beach São Tomé
Conde
$78 nightly
$91 total
Oct 26 - Oct 27
Total with taxes and fees
Roulotte Beach São Tomé
A modern living room with a black sofa, a round coffee table, and a dining area with a white table and black chairs.
A bedroom with a bed, a wardrobe, and a nightstand.
A living room with a blue sofa, a white coffee table with a remote control, a flat-screen TV, and a dining area with a table and chairs.

16. Nour Apartments

Nour Apartments
São Tomé
$48 nightly
$55 total
Sep 27 - Sep 28
Total with taxes and fees
Nour Apartments
A swimming pool with a wooden deck and a gazebo, surrounded by palm trees and a clear sky.
A white building with a covered porch, a stone pathway, and a small garden.
A neatly made bed with a wooden headboard, a bedside lamp, and a nightstand with a phone.
A restaurant with a wooden ceiling, a bar area, and a dining area with wooden furniture.

17. Praia Accommodation

Praia Accommodation
São Tomé
United States
Daniel
$112 nightly
$129 total
Sep 26 - Sep 27
Total with taxes and fees
Praia Accommodation
A swimming pool with a gazebo, palm trees, and a building in the background.
A living room with a sofa, a coffee table, and a red rug. There is a door leading to an outdoor area with a table and chairs.
A spacious dining area with a round table and chairs, large windows, and a wooden ceiling.
A beach with a palm tree and calm sea.

18. Hotel Praia

Hotel Praia
São Tomé
United States
Jonathan
$140 nightly
$161 total
Sep 26 - Sep 27
Total with taxes and fees
Hotel Praia

19. Residêncial Tamarindos

Residêncial Tamarindos
Guadalupe
United Kingdom
Maria
$42 nightly
$49 total
Oct 26 - Oct 27
Total with taxes and fees
Residêncial Tamarindos
A modern hotel room with a large bed, a chair, and a ceiling light.
A modern building with a glass railing and a marble floor.
A modern building exterior at night with a glass elevator, metal railings, and a marble floor.
A modern living room with a sectional sofa, a flat-screen TV, and a marble floor.

20. Alojamento Santos Silva

Alojamento Santos Silva
São Tomé
$309 nightly
$355 total
Sep 26 - Sep 27
Total with taxes and fees
Alojamento Santos Silva
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Learn more about Santana

Venture to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana
A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.
Photo by Fabrice Récalt

Top Santana Hotel Reviews

Hotel Central

Hotel Central

10/10 Excellent
"Hotel was good. Walking distance from everything in the city. The staff is helpful. The Wi-Fi is OK but for the money and cleanliness this is the best option in the city."
Adam 1-night trip
Posted 1 month ago
Hotel Central

More cheap stays in Santana

Nour Apartments

Nour Apartments

Rua 3 de Fevereiro São Tomé
$48 nightly
$55 total
Sep 27 - Sep 28
Total with taxes and fees
Nour Apartments
Hotel Kenito

Hotel Kenito

Campo de Milho São Tomé
$67 nightly
$78 total
Oct 4 - Oct 5
Total with taxes and fees
Hotel Kenito
Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza
$87 nightly
$100 total
Oct 20 - Oct 21
Total with taxes and fees
8.8/10 Excellent! (27 reviews)
Praia Inhame Eco-Lodge
Sweet Guest House

Sweet Guest House

Vila Dolores n. 087 São Tomé
Get ratesSweet Guest House
Inviting 10 Bed Apartment in Sao Tome

Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé
Get ratesInviting 10 Bed Apartment in Sao Tome
Pousada Roça São João dos Angolares

Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome
Get ratesPousada Roça São João dos Angolares

Frequently asked questions

What is the best area to stay in Santana?
The best area to stay in Santana is along the scenic coastal road that connects Santana to other parts of São Tomé and Príncipe.This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.
When is the best time to go to Santana?
The best time to go to Santana is during the dry season, which runs from June to September. This period offers the most pleasant weather for exploring the island.During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santana.
How much is the nightly rate at a Santana hotel?
Prices for hotels in Santana often vary, but you can find a great deal from $49 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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