Find hotels in Santana from $46

  • Upfront pricing

    Our total price for your stay includes taxes and fees

  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Jun 19 - Jun 21
Next weekend
Jun 26 - Jun 28

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santana hotels

Outdoor dining

Welfare Agroturismo

Welfare Agroturismo
3.0 star property
Trindade
$72 nightly
The price is $84
Jun 19 - Jun 20
Total with taxes and fees
Welfare Agroturismo
Lobby

Agua Leve

Agua Leve
3.0 star property
São Tomé
$50 nightly
The price is $57
Jun 19 - Jun 20
Total with taxes and fees
Agua Leve
Basic Double or Twin Room, Pool View | In-room dining

Hotel Kenito

Hotel Kenito
2.5 star property
São Tomé
10.0 out of 10, Exceptional, (4 reviews)
"The location of this property is great! The staff is accommodating and very friendly even if most don't speak English. The pool is amazing! breakfast is basic and the rooms are clean."
United States
Ada
$80 nightly
The price is $93
Jun 19 - Jun 20
Total with taxes and fees
Hotel Kenito
Beach nearby, white sand

Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
3.0 star property
Vila Maria
$139 nightly
The price is $162
Jun 20 - Jun 21
Total with taxes and fees
Emoyeni Gardens Hotel
Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board

Guest House Quinta Natural

Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1 review)
$41 nightly
The price is $47
Jun 17 - Jun 18
Total with taxes and fees
Guest House Quinta Natural
Outdoor pool

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (64 reviews)
"Lovely hotel, staff and location. Very close to airport as well Recommend highly"
United Kingdom
Kysha
$180 nightly
The price is $210
Jun 22 - Jun 23
Total with taxes and fees
Omali São Tomé – Principe Collection
Front of property

Porcelana Hotel

Porcelana Hotel
3.0 star property
Vila Maria
9.4 out of 10, Exceptional, (12 reviews)
"Great value for price. Nice staff. Excellent breakfast."
United States
Bonnie
$40 nightly
The price is $46
Jun 19 - Jun 20
Total with taxes and fees
Porcelana Hotel
Terrace/patio

Mucumbli Hotel

Mucumbli Hotel
3.0 star property
Neves
9.4 out of 10, Exceptional, (26 reviews)
"A bit rustier than i expected. Beds were SUPER sq "
Norway
Morten
$124 nightly
The price is $146
Jun 19 - Jun 20
Total with taxes and fees
Mucumbli Hotel
On the beach

Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge
2.0 star property
Malanza
8.8 out of 10, Excellent, (26 reviews)
"Bungalow is a bit outdated but good enough. Location is great and the food even better. Big thumbs up for the chefs! Best hotel food in STP for us. "
Netherlands
Rob
$100 nightly
The price is $115
Jul 10 - Jul 11
Total with taxes and fees
Praia Inhame Eco-Lodge
Standard Cabin | Laptop workspace, bed sheets

CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE
1.0 star property
Malanza
9.0 out of 10, Wonderful, (7 reviews)
"A little piece of paradise on an amazing beach. "
United Kingdom
John
$52 nightly
The price is $61
Jun 23 - Jun 24
Total with taxes and fees
CAMPISMO PRAIA GRANDE
On the beach

Residêncial Tamarindos

Residêncial Tamarindos
3.0 star property
Guadalupe
8.6 out of 10, Excellent, (14 reviews)
"Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x"
United Kingdom
Maria
$42 nightly
The price is $49
Jun 23 - Jun 24
Total with taxes and fees
Residêncial Tamarindos
Aerial view

N Guembú Nature Resort

N Guembú Nature Resort
3.0 star property
Malanza
7.4 out of 10, Good, (9 reviews)
"Very nice area and very friendly staff, who organized a trip to the island Ilhéu das Rolas with the Equator Monument. The beach on the left is fine for a swim. Good beds. Very good internet. "
Denmark
Dorte
$86 nightly
The price is $100
Jun 27 - Jun 28
Total with taxes and fees
N Guembú Nature Resort
Buffet

SH Boutique Hotel

SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (11 reviews)
"Staff were very accommodating "
United States
Simon Peter
$75 nightly
The price is $88
Jun 18 - Jun 19
Total with taxes and fees
SH Boutique Hotel
Basic Apartment | Living area | Flat-screen TV

Nour Apartments

Nour Apartments
2.5 star property
São Tomé
$52 nightly
The price is $60
Jun 19 - Jun 20
Total with taxes and fees
Nour Apartments
Standard Double Room | Bathroom | Shower, free toiletries, towels

Hotel Vitória

Hotel Vitória
3.0 star property
São Tomé
8.0 out of 10, Very Good, (4 reviews)
"Tv channel was terrible, breakfast service not good enough, most times was problem with water, electricity and wify, the staff were friendly"
United Kingdom
Anonymous traveler
$57 nightly
The price is $66
Jul 6 - Jul 7
Total with taxes and fees
Hotel Vitória
Outdoor pool, sun loungers

Praia Accommodation

Praia Accommodation
3.0 star property
São Tomé
7.4 out of 10, Good, (19 reviews)
"Great place to stay "
United States
Daniel
$108 nightly
The price is $125
Jun 18 - Jun 19
Total with taxes and fees
Praia Accommodation
Coffee shop

Hotel Central

Hotel Central
3.5 star property
São Tomé
8.0 out of 10, Very Good, (27 reviews)
"This is an excellent centrally located well-kept hotel. Close to supermarket, restaurant and sites of interest in town, Friendly staff but language can be a bit of an issue"
Ireland
Mohammad
$50 nightly
The price is $59
Jun 22 - Jun 23
Total with taxes and fees
Hotel Central
Pool

Pestana São Tomé

Pestana São Tomé
5.0 star property
Vila Maria
8.2 out of 10, Very Good, (82 reviews)
"Wonderful stay, great staff, easy, relaxing delightful."
Canada
alexander
$263 nightly
The price is $303
Jun 20 - Jun 21
Total with taxes and fees
Pestana São Tomé
Outdoor pool, pool umbrellas, sun loungers

Hotel Praia

Hotel Praia
3.5 star property
São Tomé
7.4 out of 10, Good, (18 reviews)
"Solid, basic hotel. "
United States
Jonathan
$152 nightly
The price is $178
Jun 19 - Jun 20
Total with taxes and fees
Hotel Praia
Exterior

Casa de Ferias

Casa de Ferias
3.0 star property
São Tomé
8.8 out of 10, Excellent, (6 reviews)
"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."
Sweden
Lars Roland
$63 nightly
The price is $73
Jul 16 - Jul 17
Total with taxes and fees
Casa de Ferias
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santana

Venture to São Sebastião Museum and São Nicolau Waterfall—just two of the sights around Santana.

See all hotels in Santana
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Top Santana Hotel Reviews

Hotel Kenito

Hotel Kenito

10/10 Excellent
"The location of this property is great! The staff is accommodating and very friendly even if most don't speak English. The pool is amazing! breakfast is basic and the rooms are clean."
Ada 7-night trip
Posted 2 months ago
Hotel Kenito

More cheap stays in Santana

Nour Apartments

Nour Apartments

Rua 3 de Fevereiro São Tomé
$52 nightly
The price is $60 total per night from Jun 19 to Jun 20
$60 total
Jun 19 - Jun 20
Total with taxes and fees

Frequently asked questions

What is the best area to stay in Santana?
The best area to stay in Santana is along the scenic coastal road that connects Santana to other parts of São Tomé and Príncipe.

This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.

For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.

Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.
When is the best time to go to Santana?
The best time to go to Santana is during the dry season, which runs from June to September. This period offers the most pleasant weather for exploring the island.

During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.

Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santana.
How can I save on a Santana hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santana hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santana hotel?
Prices for hotels in Santana often vary, but you can find a great deal from $46 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.