A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.

Find hotels in Santana from $45

  • Upfront pricing

    Our total price for your stay includes taxes and fees
  • Treat yourself

    Save 10% or more on over 100,000 hotels worldwide with Member Prices
    Learn about One Key
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Aug 12 - Aug 13
Tomorrow
Aug 13 - Aug 14
This weekend
Aug 14 - Aug 16
Next weekend
Aug 21 - Aug 23

Filter by

Star rating

Guest rating

Our top choices for Santana hotels

Hotel
Breakfast included
Reserve now, pay later
Pet friendly
Grill

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
Santana
Germany
Daniel
$202 nightly
$232 total
Aug 26 - Aug 27
Total with taxes and fees
Roça Santo António Ecolodge Hotel

2. Residencial Aeroporto

Residencial Aeroporto
São Tomé
$52 nightly
$60 total
Sep 12 - Sep 13
Total with taxes and fees
Residencial Aeroporto

3. Porcelana Hotel

Porcelana Hotel
Vila Maria
United States
Bonnie
$38 nightly
$45 total
Aug 17 - Aug 18
Total with taxes and fees
Porcelana Hotel

4. Hotel Kenito

Hotel Kenito
São Tomé
United States
Ada
$67 nightly
$79 total
Sep 9 - Sep 10
Total with taxes and fees
Hotel Kenito

5. Hotel Central

Hotel Central
São Tomé
Ireland
Mohammad
$48 nightly
$55 total
Aug 23 - Aug 24
Total with taxes and fees
Hotel Central

6. Welfare Agroturismo

Welfare Agroturismo
Trindade
$74 nightly
$85 total
Sep 9 - Sep 10
Total with taxes and fees
Welfare Agroturismo

7. SH Boutique Hotel

SH Boutique Hotel
São Tomé
United States
Simon Peter
$59 nightly
$68 total
Aug 13 - Aug 14
Total with taxes and fees
SH Boutique Hotel

8. Guest House Quinta Natural

Guest House Quinta Natural
Trindade
$50 nightly
$58 total
Sep 5 - Sep 6
Total with taxes and fees
Guest House Quinta Natural

9. Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
São Tomé
United Kingdom
Kysha
$176 nightly
$206 total
Aug 29 - Aug 30
Total with taxes and fees
Omali São Tomé – Principe Collection

10. Agua Leve

Agua Leve
São Tomé
$50 nightly
$57 total
Sep 9 - Sep 10
Total with taxes and fees
Agua Leve

11. Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
Vila Maria
$145 nightly
$168 total
Sep 11 - Sep 12
Total with taxes and fees
Emoyeni Gardens Hotel

12. Hotel Vitória

Hotel Vitória
São Tomé
United Kingdom
Anonymous traveler
$58 nightly
$67 total
Aug 13 - Aug 14
Total with taxes and fees
Hotel Vitória

13. Nour Apartments

Nour Apartments
São Tomé
$47 nightly
$54 total
Aug 13 - Aug 14
Total with taxes and fees
Nour Apartments

14. Residêncial Tamarindos

Residêncial Tamarindos
Guadalupe
United Kingdom
Maria
$43 nightly
$50 total
Aug 24 - Aug 25
Total with taxes and fees
Residêncial Tamarindos

15. Casa de Ferias

Casa de Ferias
São Tomé
Sweden
Lars Roland
$65 nightly
$74 total
Sep 11 - Sep 12
Total with taxes and fees
Casa de Ferias

16. Praia Accommodation

Praia Accommodation
São Tomé
United States
Daniel
$114 nightly
$131 total
Aug 31 - Sep 1
Total with taxes and fees
Praia Accommodation

17. Hotel Praia

Hotel Praia
São Tomé
United States
Jonathan
$142 nightly
$163 total
Aug 13 - Aug 14
Total with taxes and fees
Hotel Praia

18. Miramar São Tomé

Miramar São Tomé
São Tomé
United States
sandra
$228 nightly
$262 total
Aug 26 - Aug 27
Total with taxes and fees
Miramar São Tomé

19. Mucumbli Hotel

Mucumbli Hotel
Neves
Norway
Morten
$117 nightly
$138 total
Sep 9 - Sep 10
Total with taxes and fees
Mucumbli Hotel

20. CAMPISMO PRAIA GRANDE

CAMPISMO PRAIA GRANDE
Malanza
United Kingdom
John
$47 nightly
$54 total
Aug 21 - Aug 22
Total with taxes and fees
CAMPISMO PRAIA GRANDE
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Santana

Venture to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

See all hotels in Santana
A wooden bench overlooking a calm sea with a small island in the distance and lush greenery on the right.
Photo by Fabrice Récalt

Top Santana Hotel Reviews

N Guembú Nature Resort

N Guembú Nature Resort

8/10 Good
"The property requires some renovation works."
Antonio 1-night trip
Posted 1 year ago
N Guembú Nature Resort

More cheap stays in Santana

Nour Apartments

Nour Apartments

Rua 3 de Fevereiro São Tomé
$47 nightly
$54 total
Aug 13 - Aug 14
Total with taxes and fees
Nour Apartments
Hotel Kenito

Hotel Kenito

Campo de Milho São Tomé
$68 nightly
$80 total
Sep 12 - Sep 13
Total with taxes and fees
Hotel Kenito
Praia Inhame Eco-Lodge

Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza
$93 nightly
$107 total
Sep 3 - Sep 4
Total with taxes and fees
8.8/10 Excellent! (27 reviews)
Praia Inhame Eco-Lodge
Sweet Guest House

Sweet Guest House

Vila Dolores n. 087 São Tomé
Get ratesSweet Guest House
Inviting 10 Bed Apartment in Sao Tome

Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé
Get ratesInviting 10 Bed Apartment in Sao Tome
Pousada Roça São João dos Angolares

Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome
Get ratesPousada Roça São João dos Angolares

Frequently asked questions

What is the best area to stay in Santana?
The best area to stay in Santana is along the scenic coastal road that connects Santana to other parts of São Tomé and Príncipe.This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.
When is the best time to go to Santana?
The best time to go to Santana is during the dry season, which runs from June to September. This period offers the most pleasant weather for exploring the island.During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santana.
How much is the nightly rate at a Santana hotel?
Prices for hotels in Santana often vary, but you can find a great deal from $45 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia