Title: Top 10 Hotels in Santana from $63 - Competitive Prices | Expedia.com

[Vacation Rentals in Santana](https://expedia.com/Santana-Vacation-Rentals.d553248635974903086.Travel-Guide-VacationRentals)[Car Rentals in Santana](https://expedia.com/Car-Rentals-In-Santana.d553248635974903086.Car-Rental-Guide)[Santana Vacation Packages](https://expedia.com/Santana.d553248635974903086.Destination-Travel-Guides)

![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Fabrice Récalt

![](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Santana

Pool

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-03-18&d1=2026-03-18&endDate=2026-03-20&d2=2026-03-20&amenities=POOL)

Pet-friendly

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-03-18&d1=2026-03-18&endDate=2026-03-20&d2=2026-03-20&amenities=PETS)

## Check prices for these dates

Tonight

[Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-04&endDate=2026-03-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-05&endDate=2026-03-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santana hotels

![Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/afa4170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/3753b3ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic House | Living area | TV](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/6ff4185a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Guest House Quinta Natural

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information)

Trindade

10/10

Exceptional

(1 review)

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/741e11cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d9028277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/6100ac64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omali São Tomé – Principe Collection

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

São Tomé

9.4/10

Exceptional

(62 reviews)

"It’s a great resort, with friendly staff who "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Kim

$203 nightly

$235 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; Regional cuisine, pool views ](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/28b20cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, free WiFi](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bab15252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool views, open daily](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/b432c63a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pestana São Tomé

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

Vila Maria

8.0/10

Very Good

(78 reviews)

"Wonderful stay, great staff, easy, relaxing delightful."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

alexander

$203 nightly

$234 total

Mar 8 - Mar 9

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

![Basic Double or Twin Room, Pool View | In-room dining](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/13076316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/5fe608c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/0bd9a157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Kenito

[](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

São Tomé

10/10

Exceptional

(3 reviews)

"Exceptional"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nii Tetteh

$89 nightly

$103 total

Mar 14 - Mar 15

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d968c0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Triple Room | Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/90e86a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d348c5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/538d97d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mucumbli Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information)

Neves

9.4/10

Exceptional

(26 reviews)

"A bit rustier than i expected. Beds were SUPER sq "

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Morten

$135 nightly

$157 total

Apr 1 - Apr 2

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/90eb3603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/89c59b7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/f3251a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Praia Accommodation

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information)

São Tomé

7.4/10

Good

(18 reviews)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

$126 nightly

$145 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information)

![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/92cde547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/cdbf65a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/2b0a4725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e9aa90a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SH Boutique Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information)

São Tomé

8.6/10

Excellent

(10 reviews)

"Staff were very accommodating "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Simon Peter

[](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/4766b5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/468f15c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/73338a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d7eadc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Praia

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information)

São Tomé

7.4/10

Good

(18 reviews)

"Solid, basic hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

$158 nightly

$184 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information)

![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Twin Room, City View | Minibar, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/bc77b2ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/c312f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Central

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information)

São Tomé

8.2/10

Very Good

(24 reviews)

"Great value. Great location. Ok breakfast. Overall good value for money"

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Elisabeth

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/8de5668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/a14f497e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Design Triple Room | Minibar, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/b9167af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Porcelana Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information)

Vila Maria

9.6/10

Exceptional

(9 reviews)

"The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Linda

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e065a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/27ea3314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room, Corner | Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e6a8d4ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/a9318aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de Ferias

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information)

São Tomé

8.8/10

Excellent

(6 reviews)

"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."

![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg)

Lars Roland

$66 nightly

$76 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/6e86e353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/5eb72f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/ed9ed478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### N Guembú Nature Resort

[](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information)

Malanza

7.4/10

Good

(9 reviews)

"Very nice area and very friendly staff, who organized a trip to the island Ilhéu das Rolas with the Equator Monument. The beach on the left is fine for a swim. Good beds. Very good internet. "

![Denmark](https://a.travel-assets.com/egds/marks/flags/dk.svg)

Dorte

[](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/a4e1f9fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/1932dcf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/e6ae62f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite | View from room](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/1097ed78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pestana Miramar São Tomé

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information)

São Tomé

7.2/10

Good

(46 reviews)

"Very helpful and accommodating staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sandra

$149 nightly

$171 total

Mar 18 - Mar 19

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/c133a29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/27e015d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room | Minibar, individually decorated, free WiFi](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/61594a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/6b6a3057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residêncial Tamarindos

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information)

Guadalupe

8.6/10

Excellent

(14 reviews)

"Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Maria

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information)

![Standard Cabin | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/55568478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/4155521b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/746e5f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CAMPISMO PRAIA GRANDE

[](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information)

Malanza

9.0/10

Wonderful

(6 reviews)

"A little piece of paradise on an amazing beach. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

John

$54 nightly

$63 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/30a802d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Food and drink](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/72a10ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Buffet](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/b06fcbca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free cribs/infant beds](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/5142afa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Praia Inhame Eco-Lodge

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information)

Malanza

8.8/10

Excellent

(26 reviews)

"Bungalow is a bit outdated but good enough. Location is great and the food even better. Big thumbs up for the chefs! Best hotel food in STP for us. "

![Netherlands](https://a.travel-assets.com/egds/marks/flags/nl.svg)

Rob

$84 nightly

$97 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information)

![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/8c12cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/02be10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ee79bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ff5a22d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Alojamento Santos Silva 

[](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information)

São Tomé

$311 nightly

$359 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information)

![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/8fe55824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Apartment | Blackout drapes, soundproofing, free WiFi](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/895dc7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/36adc5ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nour Apartments

[](https://www.expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information)

São Tomé

$55 nightly

$63 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&regionId=553248635974903086&adults=2&sort=RECOMMENDED&openPlayBack=true)

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## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

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## Learn more about Santana

Venture to Palácio dos Congressos and Estadio Nacional 12 de Julho—just two of the sights around Santana.

[See all hotels in Santana](https://www.expedia.com/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&adults=2&regionId=553248635974903086)

![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

Photo by Fabrice Récalt

## Top Santana Hotel Reviews

![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44_y.jpg)

### Pestana São Tomé

10/10 Excellent

"Wonderful stay, great staff, easy, relaxing delightful."

[](https://expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a_y.jpg)

### Omali São Tomé – Principe Collection

10/10 Excellent

"Staff was very friendly. Food was excellent. Room was clean and well kept."

[](https://expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg)

### Hotel Kenito

10/10 Excellent

"Exceptional"

[](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

## More cheap stays in Santana

![Nour Apartments](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/895dc7c4_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Nour Apartments

Rua 3 de Fevereiro São Tomé 

$55 nightly

$63 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information)

![Praia Inhame Eco-Lodge](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/30a802d6_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza 

$84 nightly

$97 total

Mar 11 - Mar 12

Total with taxes and fees

8.8/10 Excellent! (26 reviews)

[](https://expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information)

![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Kenito

Campo de Milho São Tomé 

$89 nightly

$103 total

Mar 14 - Mar 15

Total with taxes and fees

10/10 Exceptional! (3 reviews)

[](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

![Sweet Guest House](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sweet Guest House

Vila Dolores n. 087 São Tomé 

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&selected=12336226&PinnedHotelID=12336226&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information)

![Inviting 10 Bed Apartment in Sao Tome](https://images.trvl-media.com/lodging/96000000/95320000/95318700/95318611/5916db57_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&selected=95318611&PinnedHotelID=95318611&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Inviting-10-Bed-Apartment-In-Sao-Tome.h95318611.Hotel-Information)

### Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome

[Get rates](https://expedia.com/Hotel-Search?startDate=3%2F18%2F2026&endDate=3%2F19%2F2026&selected=46350098&PinnedHotelID=46350098&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Pousada-Roca-Sao-Joao-Dos-Angolares.h46350098.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Santana?

> This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.
> 
>   
> For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.
> 
>   
> Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.

### When is the best time to go to Santana?

> During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.
> 
>   
> Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Santana hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Santana hotel?

## Explore a world of travel with Expedia

- Flights

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