Title: Top 10 Hotels in Santana from $47 - Competitive Prices | Expedia.com [Vacation Rentals in Santana](https://expedia.com/Santana-Vacation-Rentals.d553248635974903086.Travel-Guide-VacationRentals)[Car Rentals in Santana](https://expedia.com/Car-Rentals-In-Santana.d553248635974903086.Car-Rental-Guide)[Santana Vacation Packages](https://expedia.com/Santana.d553248635974903086.Destination-Travel-Guides) ![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Fabrice Récalt ![](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Go beyond your typical stay in Santana Pool [](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-03-26&d1=2026-03-26&endDate=2026-03-28&d2=2026-03-28&amenities=POOL) Pet friendly [](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe®ionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-03-26&d1=2026-03-26&endDate=2026-03-28&d2=2026-03-28&amenities=PETS) ## Check prices for these dates Tonight [Mar 12 - Mar 13](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-12&endDate=2026-03-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 13 - Mar 14](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-13&endDate=2026-03-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santana hotels ![Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/afa4170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/a9f64453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/b8ac8133.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/3753b3ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Quinta Natural [](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) Trindade 10/10 Exceptional (1 review) [](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d968c0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d348c5fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Triple Room | Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/90e86a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/49d10e40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mucumbli Hotel [](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information) Neves 9.4/10 Exceptional (26 reviews) "A bit rustier than i expected. Beds were SUPER sq " ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Morten $130 nightly $152 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information) ![Basic Double or Twin Room, Pool View | In-room dining](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/13076316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private kitchen](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/c1582a31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/0bd9a157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Kenito [](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) São Tomé 10/10 Exceptional (3 reviews) "Exceptional" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nii Tetteh $85 nightly $99 total Mar 23 - Mar 24 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/a4e1f9fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/1932dcf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/e6ae62f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | View from room](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/1097ed78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pestana Miramar São Tomé [](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information) São Tomé 7.2/10 Good (46 reviews) "Very helpful and accommodating staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sandra $148 nightly $170 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily local cuisine breakfast](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/6100ac64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d9028277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omali São Tomé – Principe Collection [](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) São Tomé 9.4/10 Exceptional (63 reviews) "Staff was very friendly. Food was excellent. Room was clean and well kept." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) christopher $193 nightly $225 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/90eb3603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/f3251a87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/89c59b7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Accommodation [](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) São Tomé 7.4/10 Good (19 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel $126 nightly $144 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information) ![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/92cde547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/de137179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room | Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/2b0a4725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e9aa90a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SH Boutique Hotel [](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) São Tomé 8.6/10 Excellent (10 reviews) "Staff were very accommodating " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Simon Peter [](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/4766b5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/73338a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d7eadc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/468f15c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Praia [](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) São Tomé 7.4/10 Good (18 reviews) "Solid, basic hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan $149 nightly $175 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information) ![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/c312f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/88c0f958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Central [](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) São Tomé 8.2/10 Very Good (25 reviews) "Great value. Great location. Ok breakfast. Overall good value for money" ![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg) Elisabeth $56 nightly $64 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e065a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Corner | Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e6a8d4ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/27ea3314.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room, Corner | Hypo-allergenic bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/fc229a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa de Ferias [](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) São Tomé 8.8/10 Excellent (6 reviews) "I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member." ![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg) Lars Roland $63 nightly $73 total Apr 11 - Apr 12 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living room](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/f180a525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/a14f497e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/8de5668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porcelana Hotel [](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) Vila Maria 9.6/10 Exceptional (9 reviews) "The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Linda $41 nightly $47 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/c133a29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Minibar, individually decorated, free WiFi](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/61594a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/27e015d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/6b6a3057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residêncial Tamarindos [](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) Guadalupe 8.6/10 Excellent (14 reviews) "Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maria [](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/6e86e353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/5eb72f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/ed9ed478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### N Guembú Nature Resort [](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information) Malanza 7.4/10 Good (9 reviews) "Very nice area and very friendly staff, who organized a trip to the island Ilhéu das Rolas with the Equator Monument. The beach on the left is fine for a swim. Good beds. Very good internet. " ![Denmark](https://a.travel-assets.com/egds/marks/flags/dk.svg) Dorte [](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bb670e49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, free WiFi](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bab15252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool views, open daily](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/b432c63a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pestana São Tomé [](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) Vila Maria 8.2/10 Very Good (79 reviews) "Wonderful stay, great staff, easy, relaxing delightful." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) alexander $202 nightly $232 total Mar 14 - Mar 15 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ![Standard Cabin | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/9357faa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/746e5f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/55568478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### CAMPISMO PRAIA GRANDE [](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) Malanza 9.0/10 Wonderful (6 reviews) "A little piece of paradise on an amazing beach. " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) John $50 nightly $59 total Mar 26 - Mar 27 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information) ![On the beach](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/30a802d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room | Desk, free cribs/infant beds](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/bdd83e01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free cribs/infant beds](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/5142afa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/72a10ea1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Praia Inhame Eco-Lodge [](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information) Malanza 8.8/10 Excellent (26 reviews) "Bungalow is a bit outdated but good enough. Location is great and the food even better. Big thumbs up for the chefs! Best hotel food in STP for us. " ![Netherlands](https://a.travel-assets.com/egds/marks/flags/nl.svg) Rob $84 nightly $97 total Mar 13 - Mar 14 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information) ![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/8c12cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ee79bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/02be10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/dfafa2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Alojamento Santos Silva [](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) São Tomé $302 nightly $350 total Mar 20 - Mar 21 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information) ![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/8fe55824.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Apartment | Blackout drapes, soundproofing, free WiFi](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/895dc7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Apartment | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/36adc5ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Nour Apartments [](https://www.expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) São Tomé $51 nightly $60 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-26&endDate=2026-03-27®ionId=553248635974903086&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=HTG_SPRING_PROMO_553248635974903086) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSantana-Hotels.d553248635974903086.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSantana-Hotels.d553248635974903086.Travel-Guide-Hotels) ## Learn more about Santana Venture to Palácio dos Congressos and Estadio Nacional 12 de Julho—just two of the sights around Santana. [See all hotels in Santana](https://www.expedia.com/Hotel-Search?startDate=2026-03-26&endDate=2026-03-27&adults=2®ionId=553248635974903086) ![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) Photo by Fabrice Récalt ## Top Santana Hotel Reviews ![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a_y.jpg) ### Omali São Tomé – Principe Collection 10/10 Excellent "Lovely hotel, staff and location. Very close to airport as well Recommend highly" [](https://expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information) ![Porcelana Hotel](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59_y.jpg) ### Porcelana Hotel 10/10 Excellent "Great value for price. Nice staff. Excellent breakfast." [](https://expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information) ![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44_y.jpg) ### Pestana São Tomé 10/10 Excellent "Wonderful stay, great staff, easy, relaxing delightful." [](https://expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg) ### Hotel Kenito 10/10 Excellent "Exceptional" [](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ## More cheap stays in Santana ![Nour Apartments](https://images.trvl-media.com/lodging/126000000/125770000/125763300/125763221/895dc7c4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Nour Apartments Rua 3 de Fevereiro São Tomé $51 nightly $60 total Apr 12 - Apr 13 Total with taxes and fees [](https://expedia.com/Sao-Tome-Hotels-Nour-Apartments.h125763221.Hotel-Information) ![Praia Inhame Eco-Lodge](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/30a802d6_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Praia Inhame Eco-Lodge Porto Alegre 64 Malanza $84 nightly $97 total Mar 13 - Mar 14 Total with taxes and fees 8.8/10 Excellent! (26 reviews) [](https://expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information) ![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Kenito Campo de Milho São Tomé $85 nightly $99 total Mar 23 - Mar 24 Total with taxes and fees 10/10 Exceptional! (3 reviews) [](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information) ![Sweet Guest House](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Sweet Guest House Vila Dolores n. 087 São Tomé [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F26%2F2026&endDate=3%2F27%2F2026&selected=12336226&PinnedHotelID=12336226&HadPinnedHotel=true®ionId=553248635974903086) [](https://expedia.com/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information) ![Inviting 10 Bed Apartment in Sao Tome](https://images.trvl-media.com/lodging/96000000/95320000/95318700/95318611/5916db57_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Inviting 10 Bed Apartment in Sao Tome Avenida Marginal 12 de Julho São Tomé São Tomé [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F26%2F2026&endDate=3%2F27%2F2026&selected=95318611&PinnedHotelID=95318611&HadPinnedHotel=true®ionId=553248635974903086) [](https://expedia.com/Sao-Tome-Island-Hotels-Inviting-10-Bed-Apartment-In-Sao-Tome.h95318611.Hotel-Information) ### Pousada Roça São João dos Angolares Cidade dos Angolares São João dos Angolares Sao Tome [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F26%2F2026&endDate=3%2F27%2F2026&selected=46350098&PinnedHotelID=46350098&HadPinnedHotel=true®ionId=553248635974903086) [](https://expedia.com/Sao-Tome-Island-Hotels-Pousada-Roca-Sao-Joao-Dos-Angolares.h46350098.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santana? > This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south. > > > For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape. > > > Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas. ### When is the best time to go to Santana? > During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets. > > > Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santana hotel booking with Expedia? > \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo. ### How much is the nightly rate at a Santana hotel? ## Explore a world of travel with Expedia - Flights - [Flights from Ribeira Afonso ](https://www.expedia.com/lp/flights/899027489549205504/flights-from-ribeira-afonso) - [Flights from Cantagalo ](https://www.expedia.com/lp/flights/899021965959114752/flights-from-cantagalo)