Title: Top 10 Hotels in Santana from $47 - Competitive Prices | Expedia.com

[Vacation Rentals in Santana](https://expedia.com/Santana-Vacation-Rentals.d553248635974903086.Travel-Guide-VacationRentals)[Car Rentals in Santana](https://expedia.com/Car-Rentals-In-Santana.d553248635974903086.Car-Rental-Guide)[Santana Vacation Packages](https://expedia.com/Santana.d553248635974903086.Destination-Travel-Guides)

![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Fabrice Récalt

![](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Go beyond your typical stay in Santana

Pool

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-02-19&d1=2026-02-19&endDate=2026-02-21&d2=2026-02-21&amenities=POOL)

Pet friendly

[](https://www.expedia.com/Hotel-Search?destination=Santana%2C+Cantagalo%2C+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe&regionId=553248635974903086&latLong=0.2532%2C6.741371&adults=2&startDate=2026-02-19&d1=2026-02-19&endDate=2026-02-21&d2=2026-02-21&amenities=PETS)

## Check prices for these dates

Tonight

[Feb 5 - Feb 6](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-02-05&endDate=2026-02-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Feb 6 - Feb 7](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-02-06&endDate=2026-02-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Feb 6 - Feb 8](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 13 - Feb 15](https://www.expedia.com/Hotel-Search?regionId=553248635974903086&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santana hotels

![Bungalow | Desk, blackout drapes, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/afa4170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/a9f64453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic House | Living area | TV](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/6ff4185a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/40000000/39490000/39486200/39486195/3753b3ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Guest House Quinta Natural

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information)

Trindade

10/10

Exceptional

(1 review)

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Guest-House-Quinta-Natural.h39486195.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/dcc8cb9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d9028277.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/741e11cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/1d47642d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omali São Tomé – Principe Collection

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

São Tomé

9.4/10

Exceptional

(62 reviews)

"It’s a great resort, with friendly staff who "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Kim

$201 nightly

$233 total

Mar 6 - Mar 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/d968c0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Triple Room | Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/90e86a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/538d97d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk](https://images.trvl-media.com/lodging/11000000/10350000/10348400/10348352/49d10e40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Mucumbli Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information)

Neves

9.4/10

Exceptional

(26 reviews)

"A bit rustier than i expected. Beds were SUPER sq "

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Morten

$138 nightly

$160 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Mucumbli-Hotel.h10348352.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/4b0f9c44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Minibar, in-room safe, free WiFi](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bab15252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; Regional cuisine, pool views ](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/28b20cc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/bb670e49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pestana São Tomé

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

Vila Maria

8.0/10

Very Good

(78 reviews)

"Wonderful stay, great staff, easy, relaxing delightful."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

alexander

$220 nightly

$253 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

![Basic Double or Twin Room, Pool View | In-room dining](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/47d5c80e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/0bd9a157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/5fe608c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/13076316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Kenito

[](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

São Tomé

10/10

Exceptional

(3 reviews)

"Exceptional"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Nii Tetteh

$59 nightly

$69 total

Mar 5 - Mar 6

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/90eb3603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Business center](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/54c71534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/89c59b7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Shower, free toiletries, towels](https://images.trvl-media.com/lodging/27000000/26600000/26593200/26593135/184b1734.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Praia Accommodation

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information)

São Tomé

7.4/10

Good

(18 reviews)

"Great place to stay "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniel

$128 nightly

$147 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Praia-Accommodation.h26593135.Hotel-Information)

![Buffet](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/92cde547.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | Minibar, in-room safe, desk, free WiFi](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/2b0a4725.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/de137179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/23000000/22450000/22443300/22443247/e9aa90a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### SH Boutique Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information)

São Tomé

8.6/10

Excellent

(10 reviews)

"Staff were very accommodating "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Simon Peter

[](https://www.expedia.com/Sao-Tome-Island-Hotels-SH-Boutique-Hotel.h22443247.Hotel-Information)

![Coffee shop](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/5e2988d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/c312f98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/88c0f958.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Staircase](https://images.trvl-media.com/lodging/38000000/37700000/37697100/37697027/fc496aaa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Central

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information)

São Tomé

8.2/10

Very Good

(24 reviews)

"Great value. Great location. Ok breakfast. Overall good value for money"

![Norway](https://a.travel-assets.com/egds/marks/flags/no.svg)

Elisabeth

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Central.h37697027.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/3a896a59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Design Triple Room | Minibar, soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/b9167af0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/a14f497e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/8de5668c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Porcelana Hotel

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information)

Vila Maria

9.6/10

Exceptional

(8 reviews)

"The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Linda

$40 nightly

$47 total

Feb 15 - Feb 16

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information)

![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/4766b5b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/73338a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/d7eadc09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/19000000/18910000/18900300/18900207/74d1540a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Praia

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information)

São Tomé

7.4/10

Good

(18 reviews)

"Solid, basic hotel. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

$161 nightly

$187 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Hotel-Praia.h18900207.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e065a121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room, Corner | Living area](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/e6a8d4ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room, Corner | Hypo-allergenic bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/fc229a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/a9318aac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa de Ferias

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information)

São Tomé

8.8/10

Excellent

(6 reviews)

"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."

![Sweden](https://a.travel-assets.com/egds/marks/flags/se.svg)

Lars Roland

$67 nightly

$77 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information)

![Aerial view](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/6e86e353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/ed9ed478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/5eb72f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### N Guembú Nature Resort

[](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information)

Malanza

7.8/10

Good

(8 reviews)

"Very nice area and very friendly staff, who organized a trip to the island Ilhéu das Rolas with the Equator Monument. The beach on the left is fine for a swim. Good beds. Very good internet. "

![Denmark](https://a.travel-assets.com/egds/marks/flags/dk.svg)

Dorte

[](https://www.expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/c133a29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Double Room | Minibar, individually decorated, free WiFi](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/61594a9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/27e015d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Balcony](https://images.trvl-media.com/lodging/23000000/22710000/22709500/22709437/6b6a3057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Residêncial Tamarindos

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information)

Guadalupe

8.6/10

Excellent

(14 reviews)

"Couldn’t have had better hosts Perfect location for great hikes and waterfalls Many thanks to Marlena and Betty who made our visit memorable x"

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Maria

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Residencial-Tamarindos.h22709437.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/dd548f89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/11ed61c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/c0fc30dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![International cuisine, pool views ](https://images.trvl-media.com/lodging/6000000/5720000/5710500/5710443/32bc16c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pestana Miramar São Tomé

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information)

São Tomé

7.2/10

Good

(45 reviews)

"Very helpful and accommodating staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

sandra

$162 nightly

$185 total

Feb 7 - Feb 8

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-Pestana-Miramar-Sao-Tome.h5710443.Hotel-Information)

![Standard Cabin | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/03f83718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/9357faa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/4155521b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Traditional Cabin, Beach View | Laptop workspace, bed sheets](https://images.trvl-media.com/lodging/105000000/104080000/104073700/104073683/746e5f79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CAMPISMO PRAIA GRANDE

[](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information)

Malanza

8.8/10

Excellent

(5 reviews)

"A little piece of paradise on an amazing beach. "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

John

$54 nightly

$63 total

Feb 18 - Feb 19

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Island-Hotels-CAMPISMO-PRAIA-GRANDE.h104073683.Hotel-Information)

![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/8c12cec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/ee79bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/dfafa2c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/121000000/120460000/120451900/120451805/02be10f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Alojamento Santos Silva 

[](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information)

São Tomé

$320 nightly

$369 total

Feb 6 - Feb 7

Total with taxes and fees

[](https://www.expedia.com/Sao-Tome-Hotels-Alojamento-Santos-Silva.h120451805.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Learn more about Santana

Venture to Estadio Nacional 12 de Julho and São Sebastião Museum—just two of the sights around Santana.

[See all hotels in Santana](https://www.expedia.com/Hotel-Search?startDate=2026-02-19&endDate=2026-02-20&adults=2&regionId=553248635974903086)

![Isn’t this a nice place to have a breakfast!](https://images.trvl-media.com/place/3486/bf4844fd-f36f-47b2-97bc-8390385f8488.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

Photo by Fabrice Récalt

## Top Santana Hotel Reviews

![Pestana São Tomé](https://images.trvl-media.com/lodging/3000000/2160000/2150500/2150447/ea6ea619_y.jpg)

### Pestana São Tomé

10/10 Excellent

"Wonderful stay, great staff, easy, relaxing delightful."

[](https://expedia.com/Sao-Tome-Island-Hotels-Pestana-Sao-Tome.h2150447.Hotel-Information)

![Omali São Tomé – Principe Collection](https://images.trvl-media.com/lodging/7000000/6770000/6762300/6762264/d1688203_y.jpg)

### Omali São Tomé – Principe Collection

10/10 Excellent

"Staff was very friendly. Food was excellent. Room was clean and well kept."

[](https://expedia.com/Sao-Tome-Island-Hotels-Omali-Sao-Tome.h6762264.Hotel-Information)

![Hotel Kriola](https://images.trvl-media.com/lodging/107000000/106990000/106989500/106989405/10340e2a_y.jpg)

### Hotel Kriola

10/10 Excellent

"Loved the mermaids in the pool"

[](https://expedia.com/Sao-Tome-Hotels-Hotel-Kriola.h106989405.Hotel-Information)

![N Guembú Nature Resort](https://images.trvl-media.com/lodging/42000000/41650000/41640400/41640341/87364023_y.jpg)

### N Guembú Nature Resort

8/10 Good

"The property requires some renovation works."

[](https://expedia.com/Sao-Tome-Island-Hotels-N-Guembu-Nature-Resort.h41640341.Hotel-Information)

![Porcelana Hotel](https://images.trvl-media.com/lodging/32000000/31070000/31068700/31068683/531924df_y.jpg)

### Porcelana Hotel

10/10 Excellent

"The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. "

[](https://expedia.com/Sao-Tome-Island-Hotels-Porcelana-Hotel.h31068683.Hotel-Information)

![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/62565a97_y.jpg)

### Hotel Kenito

10/10 Excellent

"Exceptional"

[](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

![Casa de Ferias](https://images.trvl-media.com/lodging/28000000/27100000/27093800/27093780/w1883h1080x0y0-87ed25e5_y.jpg)

### Casa de Ferias

10/10 Excellent

"It's basic, but it's the best value on sao tome"

[](https://expedia.com/Sao-Tome-Island-Hotels-Casa-De-Ferias.h27093780.Hotel-Information)

## More cheap stays in Santana

![Hotel Kenito](https://images.trvl-media.com/lodging/110000000/109260000/109259000/109258960/62565a97_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hotel Kenito

Campo de Milho São Tomé 

$59 nightly

$69 total

Mar 5 - Mar 6

Total with taxes and fees

10/10 Exceptional! (3 reviews)

[](https://expedia.com/Sao-Tome-Hotels-Hotel-Kenito.h109258960.Hotel-Information)

![Sweet Guest House](https://images.trvl-media.com/lodging/13000000/12340000/12336300/12336226/6d211eb5_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Sweet Guest House

Vila Dolores n. 087 São Tomé 

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=12336226&PinnedHotelID=12336226&HadPinnedHotel=true&regionId=553248635974903086)

8.6/10 Excellent! (44 reviews)

[](https://expedia.com/Sao-Tome-Island-Hotels-Sweet-Guest-House.h12336226.Hotel-Information)

![Praia Inhame Eco-Lodge](https://images.trvl-media.com/lodging/11000000/10400000/10392300/10392236/fa9c1d9c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Praia Inhame Eco-Lodge

Porto Alegre 64 Malanza 

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=10392236&PinnedHotelID=10392236&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Praia-Inhame-Eco-Lodge.h10392236.Hotel-Information)

![Inviting 10 Bed Apartment in Sao Tome](https://images.trvl-media.com/lodging/96000000/95320000/95318700/95318611/4c03905e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Inviting 10 Bed Apartment in Sao Tome

Avenida Marginal 12 de Julho São Tomé São Tomé

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=95318611&PinnedHotelID=95318611&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Inviting-10-Bed-Apartment-In-Sao-Tome.h95318611.Hotel-Information)

### Pousada Roça São João dos Angolares

Cidade dos Angolares São João dos Angolares Sao Tome

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=46350098&PinnedHotelID=46350098&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Pousada-Roca-Sao-Joao-Dos-Angolares.h46350098.Hotel-Information)

![Medina guest house](https://images.trvl-media.com/lodging/43000000/42410000/42408900/42408870/2d91c12c_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Medina guest house

Vila Maria Edificio Bia São Tomé 

[Get rates](https://expedia.com/Hotel-Search?startDate=2%2F19%2F2026&endDate=2%2F20%2F2026&selected=42408870&PinnedHotelID=42408870&HadPinnedHotel=true&regionId=553248635974903086)

[](https://expedia.com/Sao-Tome-Island-Hotels-Medina-Guest-House.h42408870.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in Santana?

> This area is characterized by its proximity to the ocean and lush tropical vegetation. Hotels here are typically set back from the main road, offering privacy and often direct beach access. It's a convenient location for exploring both Santana and the wider island, with easy access to attractions further north and south.
> 
>   
> For couples seeking a romantic and private retreat, this coastal stretch is ideal. Many accommodations offer ocean views, secluded beaches, and a tranquil setting great for relaxation. The natural beauty of the surroundings provides a beautiful backdrop for a memorable escape.
> 
>   
> Families will also find this area suitable due to the availability of resorts with amenities designed for all ages. These properties often feature swimming pools, spacious grounds for children to play, and easy access to calmer beach areas.

### When is the best time to go to Santana?

> During these months, you'll experience less rainfall and more sunshine, making it ideal for outdoor activities like hiking and beach visits. The ocean conditions are generally calmer, which is great for swimming, snorkeling, and boat excursions around the nearby islets.
> 
>   
> Travelers looking for a relaxed beach holiday will find this season particularly appealing, as the sunny days are excellent for enjoying Santana's coastal areas.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a Santana hotel booking with Expedia?

> \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.

### How much is the nightly rate at a Santana hotel?

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