Title: Santee Vacation Packages 2026 from $592 | Expedia.com

[Hotels in Santee](https://expedia.com/Santee-Hotels.d553248634983588478.Travel-Guide-Hotels)[Vacation Rentals in Santee](https://expedia.com/Santee-Vacation-Rentals.d553248634983588478.Travel-Guide-VacationRentals)[Car Rentals in Santee](https://expedia.com/Car-Rentals-In-Santee.d553248634983588478.Car-Rental-Guide)

![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santee Vacations from $592

## Book a Hotel + Flight or Car together to unlock savings

## The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.

![Valley Inn](https://images.trvl-media.com/lodging/4000000/3890000/3886300/3886239/38fc7edf_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Valley Inn

University Heights

$592

per person

Jun 11 - Jun 15

found 23 hours ago

Roundtrip non-stop flight included

Houston (IAH) to Sioux Falls (FSD)

7.8/10 Good! (1,002 reviews)

Our room didn’t seem like it had been cleaned thoroughly. The desk(table) was dirty with straw still in the wrapper. There was a straw wrapper on the floor. Also some crumbs by the sink. There was also still some food from the previous guest in the fridge. The bedding seemed fresh(hopefully)!!

Reviewed on Jan 28, 2026

![Clubhouse Hotel Suites Sioux Falls](https://images.trvl-media.com/lodging/2000000/1110000/1100200/1100190/4f6166ff_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Clubhouse Hotel Suites Sioux Falls

Mall District

$932

per person

Jun 11 - Jun 15

found 23 hours ago

Roundtrip non-stop flight included

Houston (IAH) to Sioux Falls (FSD)

9.4/10 Exceptional! (1,027 reviews)

Everything was perfect, the staff make check-in easy, rooms are warm and comfy the second you walk in, the pool and hot tub area was clean and relaxing. Breakfast was great. Couldn’t ask for better place to stay for a weekend.

Reviewed on Mar 9, 2026

![Hotel On Phillips](https://images.trvl-media.com/lodging/37000000/36450000/36447800/36447711/edd573eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel On Phillips

Downtown Sioux Falls

$866

per person

Jun 11 - Jun 15

found 23 hours ago

Roundtrip non-stop flight included

Houston (IAH) to Sioux Falls (FSD)

9.6/10 Exceptional! (1,363 reviews)

Clean welcoming environment at check in, friendly staff and well appointed, comfortable room in a great downtown location. The bar in a former bank vault is definitely worth a visit too.

Reviewed on Mar 19, 2026

![Historic Twin Tudors Inn](https://images.trvl-media.com/lodging/101000000/100460000/100456000/100455928/cc5b60f8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Historic Twin Tudors Inn

$896

per person

May 24 - May 26

just found

Roundtrip non-stop flight included

Los Angeles (LAX) to Sioux Falls (FSD)

8.8/10 Excellent! (3 reviews)

We were upgraded to staying at the Victorian Inn- i would highly recommended. The house is charming and located in the historic downtown of Sioux Falls.

Reviewed on Jun 16, 2025

![Gateway Park Hotel and Suites](https://images.trvl-media.com/lodging/12000000/11470000/11463300/11463225/eaa5ee68_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Gateway Park Hotel and Suites

$743

per person

Jun 11 - Jun 15

found 23 hours ago

Roundtrip non-stop flight included

Houston (IAH) to Sioux Falls (FSD)

9.2/10 Wonderful! (1,006 reviews)

Clean room and friendly staff

Reviewed on Mar 15, 2026

Don't see what you're looking for?

See all available trips from Columbus to Santee

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-21/2026-04-28/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=YKN&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

### Discover the most popular places to visit in Santee

![Niobrara showing a river or creek and boating as well as a small group of people](https://images.trvl-media.com/place/553248621532648826/8f63bdbd-db3f-4052-9d8a-54d2ed56072a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Niobrara State Park

Take photos of the iconic old railroad bridge and camp in the cabins at the confluence of the Niobrara and Missouri rivers.

[](https://expedia.com/Niobrara-State-Park-Niobrara.d553248621532648826.Vacation-Attraction)

## Santee Hotel Deals

![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/d9482fb8_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Lewis and Clark Resort

43496 Shore Drive Yankton SD

$84 nightly

$89 total

Mar 22 - Mar 23

Total with taxes and fees

8.8/10 Excellent! (299 reviews)

GREAT PLACE with perfect scenery!

Reviewed on Mar 19, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=11267995&PinnedHotelID=11267995&HadPinnedHotel=true&regionId=553248634983588478)

![Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!](https://images.trvl-media.com/lodging/123000000/122880000/122874900/122874900/d4549250_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

 Crofton NE

$813 nightly

$898 total

Mar 22 - Mar 23

Total with taxes and fees

10/10 Exceptional! (3 reviews)

Our family had a wonderful time staying in this lovely house. It is so full of light and spacious. We were able to put the littles to bed early on a different floor while the adults played loud games. The ping pong table was great entertainment to keep kids off their phones too! We would stay here ...

Reviewed on Mar 8, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&selected=122874900&PinnedHotelID=122874900&HadPinnedHotel=true&regionId=553248634983588478)

![ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18](https://images.trvl-media.com/lodging/33000000/32650000/32641200/32641183/b433a708_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

 Yankton SD

$833 nightly

$875 total

Mar 23 - Mar 24

Total with taxes and fees

9.8/10 Exceptional! (62 reviews)

The space was very nice for visiting, the kitchen was well equipped except can opener should be trashed and new one gotten. Home was clean and very bright - so many windows. Beds/sleeping was not what was posted on VRBO. Not cleaning the sidewalks and driveway in a timely manner after the snow and ...

Reviewed on Dec 3, 2025

[](https://expedia.com/Hotel-Search?startDate=3%2F23%2F2026&endDate=3%2F24%2F2026&selected=32641183&PinnedHotelID=32641183&HadPinnedHotel=true&regionId=553248634983588478)

[See all 59 properties in Santee](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=553248634983588478)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Santee Vacation Packages

## Santee Essential Information

| Language | English     |
| -------- | ----------- |
| Currency | U.S dollars |

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## Frequently asked questions

### How much does a Santee vacation package cost?

### What are the cheapest months to go to Santee?

### How many days is enough for Santee?

### How to find the best Santee package deals?

### Is it cheaper to book a Santee vacation as a package?

### When to book a vacation package to Santee?

### Does Expedia offer Book Now, Pay Later Santee vacation packages?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.