Santee Vacations from $501

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The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Bilmar Inn & Suites Dell Rapids Near Sioux Falls

Bilmar Inn & Suites Dell Rapids Near Sioux Falls

2 out of 5
Price was $557, price is now $501 per person
$501
per person
Nov 13 - Nov 15
found 20 hours ago
Roundtrip non-stop flight included
New York (NYC) to Sioux Falls (FSD)
7/10 Good! (336 reviews)
Rooms clean. Lobby a little messy. Cold cereal for breakfast. Needs more attention to details throughout.

Reviewed on Sep 21, 2026

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3 out of 5
Mall District
Price was $1,144, price is now $938 per person
$938
per person
Dec 22 - Dec 29
found 12 hours ago
Roundtrip non-stop flight included
Jackson (JAN) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,227 reviews)
Great experience and friendly staff.

Reviewed on Oct 13, 2026

Gateway Park Hotel and Suites

Gateway Park Hotel and Suites

2.5 out of 5
Price was $879, price is now $781 per person
$781
per person
Dec 22 - Dec 29
found 8 hours ago
Roundtrip non-stop flight included
Jackson (JAN) to Sioux Falls (FSD)
9.2/10 Wonderful! (1,001 reviews)

Comfort Inn & Suites Avera Southwest

Comfort Inn & Suites Avera Southwest

2.5 out of 5
South Sioux Falls
Price was $853, price is now $775 per person
$775
per person
Dec 22 - Dec 29
found 8 hours ago
Roundtrip non-stop flight included
Jackson (JAN) to Sioux Falls (FSD)
9.4/10 Exceptional! (1,015 reviews)
Breakfast was great. Loved the hot chocolate. Bed slept well and had enough pillows for someone who had knee and shoulder surgery.

Reviewed on Oct 12, 2026

Holiday Inn Express and Suites Sioux Falls SW by IHG

Holiday Inn Express and Suites Sioux Falls SW by IHG

2.5 out of 5
South Sioux Falls
Price was $820, price is now $750 per person
$750
per person
Dec 22 - Dec 29
found 8 hours ago
Roundtrip non-stop flight included
Jackson (JAN) to Sioux Falls (FSD)
8.8/10 Excellent! (1,000 reviews)

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Santee Hotel Deals

Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive Yankton SD
$113 nightly
The price is $120 total per night from Nov 1 to Nov 2
$120 total
Nov 1 - Nov 2
Total with taxes and fees
9/10 Wonderful! (352 reviews)
"Had a great time except for the neighbors keeping us up until 2-3:00 am. Kitchen floor was not very clean."

Reviewed on Oct 10, 2026

Lewis and Clark Resort
Charming Lake House within Walking Distance from Lake

Charming Lake House within Walking Distance from Lake

Yankton SD
9.6/10 Exceptional! (47 reviews)
"It was a great place to stay , it was nice the kids had their own area to hang out"

Reviewed on Sep 9, 2026

Get rates
Charming Lake House within Walking Distance from Lake
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Crofton NE
$1,085 nightly
The price is $1,199 total per night from Nov 2 to Nov 3
$1,199 total
Nov 2 - Nov 3
Total with taxes and fees
10/10 Exceptional! (10 reviews)
"Everything was great!"

Reviewed on Sep 8, 2026

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
See all 68 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santee Vacation Packages

Santee Essential Information

Language
English
Currency
U.S dollars

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Frequently asked questions

How much does a Santee vacation package cost?
You'll find cheap prices from $501 on Expedia for your Santee break. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santee costs.
What are the cheapest months to go to Santee?
If you're hoping to book a cheap Santee vacation package, consider planning a trip in November, December and January. You're likely to find lower rates on accommodations and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you time to visit all the leading attractions and discover some hidden spots along the way.
How to find the best Santee package deals?
Start your search for a Santee package deal by entering your preferred trip dates and destination under our "Packages" tab. Then select some filters, like "Property type" and "Popular locations," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santee package deal right away, just tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santee escape off to a flying start.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking hotels and flights separately. Better still, you can customize your Santee trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates confirmed, book as soon as you can to snap up some awesome deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are great for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
Your Santee break should be a relaxing escape from your busy life, not a source of money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.