Santee Vacations from $404

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The Latest Santee vacation packages

Price found within the past 48 hours. Click for updated prices.
Historic Twin Tudors Inn

Historic Twin Tudors Inn

3 out of 5
Price was $485, price is now $404 per person
$404
per person
Nov 7 - Nov 9
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Sioux Falls (FSD)
8.8/10 Excellent! (3 reviews)
We were upgraded to staying at the Victorian Inn- i would highly recommended. The house is charming and located in the historic downtown of Sioux Falls.

Reviewed on Jun 16, 2025

Gateway Park Hotel and Suites

Gateway Park Hotel and Suites

2.5 out of 5
Price was $572, price is now $480 per person
$480
per person
Nov 7 - Nov 9
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Sioux Falls (FSD)
9.2/10 Wonderful! (1,003 reviews)
Outside the property and parking lot is filled garbage and cigarette butts. Landscaping is dead or overgrown. The pool was ice cold. The room and bedding was covered in dog hair. Popcorn left in the pull out couch from previous guest. Shower sprayed water out the top of the spout.

Reviewed on Sep 27, 2025

Hotel On Phillips

Hotel On Phillips

2.5 out of 5
Downtown Sioux Falls
Price was $543, price is now $465 per person
$465
per person
Oct 31 - Nov 2
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,190 reviews)
Very nice hotel and comfy beds, but aside from the valet, the two individuals we encountered at the front desk may have been the most least friendly individuals I've ever encountered at any hotel front desk. Not one smile nor nice word (how about "welcome" or " enjoy your stay" or even ask " how was your stay & goodbye", I would even have accepted a smile.

Reviewed on Sep 24, 2025

Clubhouse Hotel Suites Sioux Falls

Clubhouse Hotel Suites Sioux Falls

3 out of 5
Price was $497, price is now $440 per person
$440
per person
Oct 31 - Nov 2
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Sioux Falls (FSD)
9.6/10 Exceptional! (1,012 reviews)
Very nice hotel my only complaint is it is difficult to cal the hotel directly as all the numbers are for corporate or a computer

Reviewed on Sep 27, 2025

AmericInn by Wyndham Sioux Falls North

AmericInn by Wyndham Sioux Falls North

2.5 out of 5
Price was $460, price is now $410 per person
$410
per person
Oct 31 - Nov 2
found 21 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Sioux Falls (FSD)
9/10 Wonderful! (1,429 reviews)
Have stayed here previously. This stay was very noisy. heard walking above us from 12:30 - 3:00 a.m. We could also here people talking in the rooms next to us. Quite a bit of banging/knocking. Noise woke me twice.

Reviewed on Sep 26, 2025

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Discover the most popular places to visit in Santee

Niobrara showing a river or creek and boating as well as a small group of people

Niobrara State Park

Take photos of the iconic old railroad bridge and camp in the cabins at the confluence of the Niobrara and Missouri rivers.

Niobrara State Park

Santee Hotel Deals

Lewis and Clark Resort

Lewis and Clark Resort

2.5 out of 5
43496 Shore Drive, Yankton, SD
$103 nightly
The price is $109 total per night from Sep 29 to Sep 30
$109 total
Sep 29 - Sep 30
Total with taxes and fees
8.6/10 Excellent! (257 reviews)
"Enjoyed outdoor"

Reviewed on Sep 13, 2025

Lewis and Clark Resort
Gavins Point Lakehouse

Gavins Point Lakehouse

Yankton
10/10 Exceptional! (6 reviews)
Simply Stunning
"Property was stunning. Views from the home are stunning and the memories we made were u forgettable. Beds and pillows were all comfortable and the kitchen was stocked with the tools to allow you to prepare whatever upur heart desired. Communication was simple and responses were quick. Definitely ..."

Reviewed on Aug 3, 2025

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Gavins Point Lakehouse
Spacious Lakeview Cabin Minutes from Private Beach

Spacious Lakeview Cabin Minutes from Private Beach

Crofton
9.4/10 Exceptional! (9 reviews)
"Very spacious accomodations and a beautiful view. Communications with owners was fantastic. We had a totally different expectation of the private beach, it was disappointing but we were very close to other places."

Reviewed on Jul 29, 2025

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Spacious Lakeview Cabin Minutes from Private Beach
See all 61 properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Santee vacation package cost?
You'll find cheap prices from $404 on Expedia for your Santee break. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santee costs.
What are the cheapest months to go to Santee?
If you're hoping to book a cheap Santee vacation package, consider planning a trip in November, December and January. You're likely to find lower rates on accommodations and flights during these months — ideal for a budget-friendly break.
How many days is enough for Santee?
The ideal length for your Santee vacation depends on what you'd like to see and do. Generally, a handful of days to a week will give you time to visit all the leading attractions and discover some hidden spots along the way.
How to find the best Santee package deals?
Start your search for a Santee package deal by entering your preferred trip dates and destination under our "Packages" tab. Then select some filters, like "Property type" and "Popular locations," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the ideal Santee package deal right away, just tweak your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santee escape off to a flying start.
Is it cheaper to book a Santee vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking hotels and flights separately. Better still, you can customize your Santee trip to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santee?
If you have your Santee vacation dates confirmed, book as soon as you can to snap up some awesome deals. With Expedia, you can typically reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are great for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santee vacation packages?
Your Santee break should be a relaxing escape from your busy life, not a source of money-related stress. So to allow you that extra flexibility, we've partnered with online lender Affirm to offer you our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.