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Find hotels in Santee, NE from $131

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This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

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Our top choices for Santee hotels

Hotel
Family Quadruple Room | Living area | 32-inch LCD TV with digital channels, TV

Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (325 reviews)
"Fishing trip for three adult men. Good for what we was after. Good place for family stay. Only the one bathroom would be the only complaint if more people were along. Great view of lake."
United States
Mark
$124 nightly
The price is $131
Jul 14 - Jul 15
Total with taxes and fees
Lewis and Clark Resort
Lobby

Comfort Inn Yankton SD

Comfort Inn Yankton SD
2.5 star property
Yankton
8.8 out of 10, Excellent, (745 reviews)
"Great property! Very friendly staff!"
United States
Cynthia
$107 nightly
The price is $118
Jul 19 - Jul 20
Total with taxes and fees
Comfort Inn Yankton SD
Interior

The Historic Argo Hotel

The Historic Argo Hotel
3.0 star property
Crofton
8.0 out of 10, Very Good, (1 review)
"Rooms were clean. Bed was great. Breakfast was delicious. ac comfortable. Might reconsider toys in foyer."
United States
Fred
$171 nightly
The price is $192
Jul 13 - Jul 14
Total with taxes and fees
The Historic Argo Hotel
Interior

Peaceful bed & breakfast with AC in charming Crofton

Peaceful bed & breakfast with AC in charming Crofton
Crofton
$198 nightly
The price is $222
Jul 11 - Jul 12
Total with taxes and fees
Peaceful bed & breakfast with AC in charming Crofton
3 bedrooms, WiFi, bed sheets

Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort

Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort
Yankton
Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort
Interior

Welcoming bed & breakfast with AC in charming Crofton

Welcoming bed & breakfast with AC in charming Crofton
Crofton
Welcoming bed & breakfast with AC in charming Crofton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular attractions around Santee

Nestled in the heart of nature, Santee offers a perfect escape for outdoor enthusiasts and romance seekers alike. With stunning parks, serene lakes, and breathtaking scenery, you'll find countless opportunities for family adventures and eco-friendly experiences that create lasting memories.

Niobrara State Park

10.0/10 (3 reviews)
Ideal for outdoor enthusiasts, Niobrara State Park offers breathtaking scenery and adventure in a serene setting. Located about 12 miles from Santee, this park is perfect for exploring nature while providing easy access to nearby attractions, making it a convenient base for your vacation.
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Top Santee Hotel Reviews

Haven by the Lake

Haven by the Lake

10/10 Excellent
"If you want clean, quiet, and relaxation, this is the place. Super cool host and AMAZING wildlife all around the property. Great stay!"
Karlis A. 4-night trip
Posted 3 hours ago
Haven by the Lake

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive Yankton SD
$124 nightly
The price is $131 total per night from Jul 14 to Jul 15
$131 total
Jul 14 - Jul 15
Total with taxes and fees
8.8/10 Excellent! (325 reviews)

Hotels in Santee with star-rating

Frequently asked questions

What is the best area to stay in Santee?
The best area to stay in Santee is within the main part of the village, particularly near the Santee Sioux Nation's Ohiya Casino & Resort. This area serves as the primary hub for visitor amenities and activities.

The Ohiya Casino & Resort is the focal point of the village, offering lodging, dining, and entertainment options. It's located just off Highway 12, making it easily accessible. This area is convenient for solo travelers and couples looking for entertainment and comfortable accommodations in a central location.

For visitors interested in the cultural aspects of the Santee Sioux Nation, staying near the casino and resort allows easy access to tribal events and community gatherings that are often held in the vicinity.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santee.
How can I save on a Santee hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santee hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santee hotel?
Prices for hotels in Santee often vary, but you can find a great deal from $131 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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