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Find hotels in Santee, NE from $100

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Aug 28 - Aug 29
Tomorrow
Aug 29 - Aug 30
This weekend
Aug 28 - Aug 30
Next weekend
Sep 4 - Sep 6

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Our top choices for Santee hotels

A spacious kitchen with a large island, modern pendant lights, and a ceiling fan.
A modern kitchen with stainless steel appliances, dark wood cabinets, and a tiled floor.
Two people sitting on Adirondack chairs facing a lake, with picnic tables and benches in the background.
A modern kitchen with dark cabinets, stainless steel appliances, and a large window.

1. Lewis and Clark Resort

Lewis and Clark Resort
Yankton
Guest review highlights
  • Brand new swimming pool
  • Beautiful outlook from the rooms
  • Consistent daily housekeeping service
$94 nightly
$100 total
Aug 31 - Sep 1
Total with taxes and fees
Lewis and Clark Resort
A hotel lobby with a reception desk, seating area, and a large window with a view of a building.
A Comfort Inn hotel with a covered entrance, a parking lot, and a clear sky.
A spa area with a hot tub, seating, and a view of the parking lot.
A hotel room with two beds, a desk, a chair, and a framed picture on the wall.

2. Comfort Inn Yankton SD

Comfort Inn Yankton SD
Yankton
Guest review highlights
  • Wonderful continental breakfast options
  • Clean and well-kept property
  • Very friendly and helpful staff
$113 nightly
$124 total
Sep 7 - Sep 8
Total with taxes and fees
Comfort Inn Yankton SD
A grand staircase with wooden railings and a red flag, leading to a room with a patterned ceiling and string lights.
A bedroom with a bed, a bedside table, a lamp, and a mirror.
A neatly made bed with a patterned bedspread and pillows, a bedside lamp, and a window with closed blinds.
A bedroom with a bed, bedside table, lamp, and a window with blinds.

3. The Historic Argo Hotel

The Historic Argo Hotel
Crofton
Guest review highlights
  • Delicious breakfast with fresh options
  • Clean, comfortable rooms
$146 nightly
$163 total
Sep 27 - Sep 28
Total with taxes and fees
The Historic Argo Hotel
A grand staircase with wooden railings and a red flag, leading to a room with a patterned ceiling and string lights.
A four-poster bed with a red and gold bedspread, a white lace footboard, and a wooden headboard. There is a nightstand with a lamp and a remote control beside the bed.
A bathroom with a red bathtub, a white sink, and a red sofa.
A bathroom with a toilet, bidet, and dark wooden vanity with a mirror.

4. Peaceful bed & breakfast with AC in charming Crofton

Peaceful bed & breakfast with AC in charming Crofton
Crofton
$200 nightly
$224 total
Aug 29 - Aug 30
Total with taxes and fees
Peaceful bed & breakfast with AC in charming Crofton
A wooden interior with a hallway leading to a bedroom, a chevron-patterned wall art, and a ceiling light.
A kitchen with wooden cabinets, a granite countertop, a stove, and a refrigerator.
A wooden cabin interior with a spiral staircase, a dining area, a living room with a sofa, and a kitchen.
A building with a green roof, a sign reading 'Northwood Nest,' outdoor seating with wooden chairs, and a picnic table.

5. Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort

Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort
Yankton
Family-friendly log cabin style house by Lewis & Clark Lake at DJ's Resort
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Stay near popular attractions around Santee

Nestled in the heart of nature, Santee offers a perfect escape for outdoor enthusiasts and romance seekers alike. With stunning parks, serene lakes, and breathtaking scenery, you'll find countless opportunities for family adventures and eco-friendly experiences that create lasting memories.

Niobrara State Park

10.0/10 (3 reviews)
Ideal for outdoor enthusiasts, Niobrara State Park offers breathtaking scenery and adventure in a serene setting. Located about 12 miles from Santee, this park is perfect for exploring nature while providing easy access to nearby attractions, making it a convenient base for your vacation.
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Lewis and Clark Lake

9.2/10 (57 reviews)
Experience the best of outdoor adventure at Lewis and Clark Lake, a scenic destination perfect for couples and families alike. Enjoy the romantic atmosphere, breathtaking views, and beach vibes that make this lake a must-visit. Located about 7 miles from Santee, it offers convenient access for a memorable getaway.
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Bloomfield Recreation Area

Ideal for families seeking outdoor adventures, Bloomfield Recreation Area offers a serene setting with eco-friendly vibes. Located about 11 miles from Santee, this park features lush landscapes and recreational opportunities. Staying nearby provides easy access to a peaceful retreat for nature lovers.
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Pebble Beach

No trip is complete without a visit to Pebble Beach, a perfect spot for families seeking a relaxing day by the water. With its inviting beach vibes, this destination offers a unique experience for those looking to unwind. Located about 13 miles from Santee, it’s an easy excursion that enhances your stay in the area.
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Sioux Council Boy Scout Reservation

Discover the appeal of this family-friendly park, the Sioux Council Boy Scout Reservation, located in Tabor, South Dakota. Known for its outdoor and eco-friendly vibes, it offers a perfect setting for nature lovers. Situated about 13 miles from Santee, it's a convenient stop for a refreshing getaway.
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Lesterville Recreation Area

For families seeking outdoor adventures, Lesterville Recreation Area offers a picturesque escape with its eco-friendly vibes and ample recreational opportunities. Situated about 14 miles from Santee, this park is perfect for enjoying nature and creating lasting memories, making it a convenient choice for your getaway.
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Top Santee Hotel Reviews

The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska

The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska

10/10 Excellent
"The stay was absolutely wonderful! The property was beautiful, clean, comfortable, and exactly as described. The host was friendly, responsive, and made everything easy from check-in to check-out. We had a fantastic experience and would happily stay here again. Highly recommended!"
Anonymous traveler 1-night trip
Posted 4 days ago
The Bohemian Bungalow near Main Street in Scenic Verdigre, Nebraska
Spacious Lakeview Cabin Minutes from Private Beach

Spacious Lakeview Cabin Minutes from Private Beach

10/10 Excellent
"Lots of room for sleeping - open spacious living room with a beautiful lake view."
Kaylee O. 3-night trip
Posted 5 days ago
Spacious Lakeview Cabin Minutes from Private Beach
Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"This condo was beautiful! Very clean and well maintained. Great location for everything we wanted to do in the Okoboji area. Would definitely stay here again."
Melissa 3-night trip
Posted 10 days ago
Lewis and Clark Resort
Family, friendly country farm home. Enjoying peace and quiet.

Family, friendly country farm home. Enjoying peace and quiet.

10/10 Excellent
"This house had everything we needed for our family’s stay. The kids really enjoyed the garage space. So many things to keep them entertained. House was very clean and AC worked great! So convenient that each family had their own bathroom. Beautiful view from the deck with morning coffee."
Ann B. 2-night trip
Posted 12 days ago
Family, friendly country farm home. Enjoying peace and quiet.
Haven by the Lake

Haven by the Lake

10/10 Excellent
"Great getaway spot with easy access to the state park and its trails and beaches. Our family spent every day at the beach from here."
Jim S. 7-night trip
Posted 12 days ago
Haven by the Lake
Fully furnished lake house with cozy spaces, full kitchen, and lake views.

Fully furnished lake house with cozy spaces, full kitchen, and lake views.

10/10 Excellent
"Very accommodating."
Jason W. 3-night trip
Posted 3 weeks ago
Fully furnished lake house with cozy spaces, full kitchen, and lake views.
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake

10/10 Excellent
"Checked all the boxes for what we needed for this stay, thanks Tony !"
Sheena A. 2-night trip
Posted 1 month ago
Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake
Charming Lake House within Walking Distance from Lake

Charming Lake House within Walking Distance from Lake

10/10 Excellent
"Great location and great host! Quick communication from Katie every time. Very family-friendly!"
Lisa M. 3-night trip
Posted 1 month ago
Charming Lake House within Walking Distance from Lake
Waterfront Crofton Cabin - Boat Dock & Fire Pit!

Waterfront Crofton Cabin - Boat Dock & Fire Pit!

10/10 Excellent
"Would stay again"
Matthew T. 5-night trip
Posted 1 month ago
Waterfront Crofton Cabin - Boat Dock & Fire Pit!

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive Yankton SD
$94 nightly
$100 total
Aug 31 - Sep 1
Total with taxes and fees
9/10 Wonderful! (333 reviews)
Lewis and Clark Resort

Hotels in Santee with star-rating

Frequently asked questions

What is the best area to stay in Santee?
The best area to stay in Santee is within the main part of the village, particularly near the Santee Sioux Nation's Ohiya Casino & Resort. This area serves as the primary hub for visitor amenities and activities.The Ohiya Casino & Resort is the focal point of the village, offering lodging, dining, and entertainment options. It's located just off Highway 12, making it easily accessible. This area is convenient for solo travelers and couples looking for entertainment and comfortable accommodations in a central location.For visitors interested in the cultural aspects of the Santee Sioux Nation, staying near the casino and resort allows easy access to tribal events and community gatherings that are often held in the vicinity.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santee.
How much is the nightly rate at a Santee hotel?
Prices for hotels in Santee often vary, but you can find a great deal from $100 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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