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Our top choices for Santee hotels

Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (286)
"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
United States
Jessica
$94 nightly
The price is $99
Jan 11 - Jan 12
Total with taxes and fees
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in Santee?
The best area to stay in Santee is within the main part of the village, particularly near the Santee Sioux Nation's Ohiya Casino & Resort. This area serves as the primary hub for visitor amenities and activities.

The Ohiya Casino & Resort is the focal point of the village, offering lodging, dining, and entertainment options. It's located just off Highway 12, making it easily accessible. This area is convenient for solo travelers and couples looking for entertainment and comfortable accommodations in a central location.

For visitors interested in the cultural aspects of the Santee Sioux Nation, staying near the casino and resort allows easy access to tribal events and community gatherings that are often held in the vicinity.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santee.
How can I save on a Santee hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santee hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santee hotel?
Prices for hotels in Santee often vary, but you can find a great deal from $99 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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