Plan your trip

Santi Cosma e Damiano Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

  • Check prices for these dates

    Check prices for these dates, December 13 – 14, 2026

    View in a map

    Our top choices for Santi Cosma e Damiano vacation rentals

    1. A little paradise surrounded by greenery, just a stone's throw from the sea

    An outdoor patio with a table and chairs, a large umbrella, and potted plants.

    2. Country House Bosco d'Olmi

    A swimming pool with a curved edge, a large barrel sculpture, and a view of mountains in the background.

    3. Le Cinèma

    A hotel room with a large bed, two rolled towels, a desk with a chair, a potted plant, and a mirror.

    4. B&B Parini

    A small wooden bedside table with a drawer, a white lamp, and a quilted brown chair.

    5. Villa Elisa Apartments

    A balcony with a white railing, potted plants with red flowers, and a view of trees and distant landscape.

    6. Dimora Domitia

    A rooftop terrace with a hot tub, red chairs, a table, a bottle of wine, and glasses.

    7. CasadiCampo II

    A well-maintained grassy lawn with a white building featuring a red roof, surrounded by trees and a clear blue sky.

    8. Aria di Casa Experience - Private Room with Private Bathroom

    A bedroom with a bed, two bedside tables, a nightstand, a painting, and a wall art piece.

    9. BEAUTIFUL NEW APARTMENT WITH LARGE TERRACE - A CASA DI CAROLINA

    A modern living room with a sofa, a coffee table, a potted plant, and a dining area with a table and chairs.

    10. Alloggio Turistico Belvedere

    A coastal town with a prominent tower, a marina with boats, and buildings with Mediterranean architecture.

    11. Dimora del Prete di Belmonte - Bed & Breakfast

    A grand hallway with an arched ceiling, a wooden bench, and a cabinet with decorative items.

    12. Villa 'Lucia' with Shared Terrace and Wi-Fi

    A balcony with a table, a hanging chair, and a view of greenery.

    13. Apartment 'B' with Sea View, Garden, Private Terrace, and Wi-Fi

    A building with a white facade, a balcony with a balustrade, and a staircase leading to the entrance.

    14. CasadiCamp

    A well-maintained grassy lawn with a white building featuring a red roof, surrounded by trees and a clear blue sky.

    15. Luxury beachfront holiday home in Formia Vindico

    An outdoor patio with a table and chairs, overlooking a body of water and a distant island.

    16. Sapore Di Mare Riviera

    A modern bedroom with a bed, bedside tables, and a hanging light fixture.

    17. LA PERLA AZZURRA

    A marina with numerous boats docked, a gas station, and a view of historic buildings in the background.

    18. Terrazza sul Mare

    A rooftop terrace with a clear sky, buildings in the background, and a distant view of the sea.

    19. BELVEDERE - Bed & Breakfast - Vacation Home

    A two-story house with a tiled roof, arched windows, and a balcony.

    20. Apartment with Ocean View in GAETA

    A rooftop terrace with a view of the sea and mountains.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

    View all properties

    Find vacation rentals that suit your style

    Apartments

    Aparthotels

    Condos

    Villas

    Top Santi Cosma e Damiano Hotel Reviews

    Villa Maria Teresa Boutique Hotel

    A terrace with white wicker chairs and tables, a white umbrella, and a view of the sea and a distant hill.

    Kora Park Resort

    Front of property

    Edra Palace

    A hotel with a swimming pool, outdoor seating, and a large building in the background.

    Villa Caribe Resort & Spa - Adult Recommended

    A nighttime view of a resort with palm trees, a pool, and lounge chairs.

    Country House Bosco d'Olmi

    A swimming pool with a curved edge, a large barrel sculpture, and a view of mountains in the background.

    Hotel Ristorante Al Boschetto

    A landscaped garden with a fountain, surrounded by trees and a building in the background.

    Le Cinèma

    A hotel room with a large bed, two rolled towels, a desk with a chair, a potted plant, and a mirror.

    Agriturismo il Pioppeto

    A stone building with a patio area featuring outdoor seating and potted plants.

    Villa Irlanda Grand Hotel

    An aerial view of a coastal resort with a large swimming pool, multiple buildings, and a beach with boats.

    Hotel Liolá

    A garden patio with a stone pathway, outdoor furniture, and a large umbrella.

    Best Western Hotel Rocca

    A modern hotel with a landscaped garden, palm trees, and a fountain.

    Hotel Tirreno

    A beach with numerous umbrellas and people.

    B&B Parini

    A small wooden bedside table with a drawer, a white lamp, and a quilted brown chair.

    B&B Il Girasole

    A beach with rows of sun loungers and umbrellas, a fence, and a view of the sea and distant hills.

    Dimora del Prete di Belmonte - Bed & Breakfast

    A grand hallway with an arched ceiling, a wooden bench, and a cabinet with decorative items.

    Find out more about Santi Cosma e Damiano

    Everything you need to know about Santi Cosma e Damiano vacation rentals

    Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santi Cosma e Damiano vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

    There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santi Cosma e Damiano vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

    Santi Cosma e Damiano vacation rentals: An excellent choice for every season

    Whenever you want to travel, a warm welcome awaits you in Santi Cosma e Damiano. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santi Cosma e Damiano in high season.

    Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $51 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

    How to find incredible deals on Santi Cosma e Damiano rentals

    At Expedia, we put the best Santi Cosma e Damiano vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

    To find some top Santi Cosma e Damiano rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santi Cosma e Damiano vacation.

    If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santi Cosma e Damiano. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

    Frequently Asked Questions

    Can I find a vacation rental in Santi Cosma e Damiano?

    Yes, you can find vacation rentals near well known local attractions in Santi Cosma e Damiano, or you can go with a more remote option if you'd like a relaxing place to stay.

    What's the top vacation rental in Santi Cosma e Damiano?

    Country House Bosco d'Olmi: You might want to consider this vacation home rental near Santi Cosma e Damiano, which offers an outdoor pool, a terrace, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. Kitchen amenities like a fridge and kitchenware can make your vacation run smoothly. It offers a garden, a selection of games, and a hot tub so you can immerse yourself in your vacation.

    What’s there to see and do in Santi Cosma e Damiano?

    While exploring the area, visit family-friendly sights like Maremoto Windsurf Center, or get outside and enjoy nature at Marina di Minturno Beach. Spiaggia di Scauri and Sassolini Beach are a couple of places you'll find in the larger area.

    What’s a vacation rental in Santi Cosma e Damiano like?

    A vacation rental is a private property you can book for a few weeks or just a few days in Santi Cosma e Damiano. Vacation rentals feature extras like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a clean environment, vacation rentals can offer a sense of seclusion away from shared hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a great option for small groups.

    Explore a world of travel with Expedia