Santissima Annunziata Vacations from $1,097
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Santissima Annunziata Vacation
Organizing your next travel adventure just got simpler with a vacation package to Santissima Annunziata. Enjoy all this neighborhood has to offer while making incredible memories you'll remember for years. Kick start your trip to Santissima Annunziata with a visit to nearby attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia is here to help put your travel plans into action. Book your ultimate Santissima Annunziata vacation now.
The Latest Santissima Annunziata Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Aurum Firenze
Historic Centre of Florence
Price was $1,706, price is now $1,097 per person
$1,097
per person
Jul 21 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,004 reviews)
Our room was very small. The bathroom was very tight. The breakfast was so so. We had so much better.our other hotel in Venice. The breakfast room is tight and not much in pastries
Reviewed on May 1, 2026
Aurum Uffizi
Historic Centre of Florence
Price was $1,743, price is now $1,109 per person
$1,109
per person
Jul 21 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,006 reviews)
Excellent helpful staff let us store our bags in the lobby for a couple of hours after checkout- much appreciated- clean and quiet - central location was walkable to everywhere- and they were very nice to our 6 month old baby
Reviewed on May 2, 2026
Plaza Hotel Lucchesi
Historic Centre of Florence
Price was $2,162, price is now $1,537 per person
$1,537
per person
Jul 21 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (1,001 reviews)
Internet struggles when in the rooms, but the rooftop bar/pool area has strong wifi and it's a much better place to setup if you have to do some light work. The views are stunning from the rooftop, you can watch the sun set and skip the tourist trap spots for that. The staff is incredibly kind and helpful. The bar staff makes the absolute best Aperol Spritz we found in the city as well as a Hugo Spritz (our new favorite). Breakfast is delicious and covers both local and international options. We highly recommend staying here as it's perfectly located in the city for all the major sightseeing options. Will definitely be back.
Reviewed on Apr 25, 2026
L'Andana
Price was $3,084, price is now $2,197 per person
$2,197
per person
Jun 3 - Jun 8
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (86 reviews)
What an amazing place I hope to get back here next year again everybody was super nice. Property was super nice. It is quite relaxing. Great food apparently a great wine as well but I don’t drink. I highly recommend anybody to go.
Reviewed on Jul 5, 2025
Hotel Villani
Historic Centre of Florence
Price was $1,849, price is now $1,323 per person
$1,323
per person
Jul 21 - Jul 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
8.6/10 Excellent! (483 reviews)
The staff was amazing- friendly and helpful. The hotel has a bit of a retro vibe, which I really liked. My side of the bed wasn’t very comfortable, but my partners side was. Breakfast was so good that I almost asked for recipes. And the location cannot be beat!
Reviewed on May 2, 2026
Where to stay in Santissima Annunziata
Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santissima Annunziata Hotel Deals
Forte16 View & Spa
Viale Antonio Gramsci 16 Florence FI
Fully refundableReserve now, pay when you stay
$204 nightly
The price is $238 total per night from May 10 to May 11
$238 total
May 10 - May 11
Total with taxes and fees
9.6/10 Exceptional! (947 reviews)
Hotel is amazing!! Great pool, with steam and sauna available, Rooftop Private Jacuzzi sessions available for a price, Water machine, wine dispenser machine, Great staff, amazing location, laundry available on site, You cannot ask for anymore, Great breakfast buffet, either pre book or pay, Rooftop ...
Reviewed on May 1, 2026
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
$576 nightly
The price is $652 total per night from Jun 3 to Jun 4
$652 total
Jun 3 - Jun 4
Total with taxes and fees
9.4/10 Exceptional! (447 reviews)
The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff.
Reviewed on Apr 12, 2026
Four Seasons Hotel Firenze
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
$1,969 nightly
The price is $2,185 total per night from May 31 to Jun 1
$2,185 total
May 31 - Jun 1
Total with taxes and fees
9.8/10 Exceptional! (303 reviews)
One of the best hotels that I have ever stayed in. Great location in Florence and impeccable service all around.
Reviewed on Apr 18, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santissima Annunziata
Gallery of the Academy of Florence
4.5/5(1,113 reviews)
Michelangelo’s David statue is the impressive star of the show at one of Florence’s most popular and well-attended art museums.
Statue of David
5/5(374 reviews)
You can learn about the history of Florence with a stop at Statue of David. Experience the acclaimed art scene and fascinating museums in this vibrant area.
Santissima Annunziata Square
5/5(2 reviews)
Find out about the history of Florence when you spend time at Santissima Annunziata Square. Experience the fascinating museums and acclaimed art scene in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$34
per adult
76% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
$105
per adult
98% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$28
per adult
80% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.