Santissima Annunziata Vacations from $941

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Your Santissima Annunziata Vacation

Organizing your next travel adventure just got simpler with a vacation package to Santissima Annunziata. Enjoy all this neighborhood has to offer while making incredible memories you'll remember for years. Kick start your trip to Santissima Annunziata with a visit to nearby attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia is here to help put your travel plans into action. Book your ultimate Santissima Annunziata vacation now.

The Latest Santissima Annunziata Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Villa Kinzica

Hotel Villa Kinzica

3 out of 5
Pisa City Centre
per person
Sep 1 - Sep 8
found 7 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
7.6/10 Good! (762 reviews)
This property was right down the road from the monuments.

Reviewed on Jul 16, 2025

Bagni di Pisa Palace & Thermal Spa

Bagni di Pisa Palace & Thermal Spa

5 out of 5
Save 100% on your flight
per person
Sep 1 - Sep 8
found 7 hours ago
Roundtrip non-stop flight included
New York (JFK) to Florence (FLR)
8.6/10 Excellent! (242 reviews)
We had a wonderful stay in this exceptional property, the staff were great and the dinning was excellent.

Reviewed on Jul 1, 2025

Aurum Firenze

Aurum Firenze

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Oct 14 - Oct 20
found 18 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
7.6/10 Good! (1,012 reviews)
The hotel is situated on busy street, it is walking distance from Santa Maria train station, the room was clean but small and the breakfast was average.

Reviewed on Jul 25, 2025

Grand Hotel Cavour

Grand Hotel Cavour

4 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 25 - Oct 1
found 15 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,002 reviews)
Muy bonita bien, situada muy buen desayuno, el personal muy atento

Reviewed on Jul 24, 2025

Palazzo Firenze by Baglioni Hotels & Resorts

Palazzo Firenze by Baglioni Hotels & Resorts

5 out of 5
Historic Centre of Florence
Save 100% on your flight
per person
Sep 25 - Sep 30
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.4/10 Exceptional! (228 reviews)
I VERY MUCH ENJOYED THE STAY

Reviewed on Jul 18, 2025

Where to stay in Santissima Annunziata

Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Santissima Annunziata Hotel Deals

Four Seasons Hotel Firenze

Four Seasons Hotel Firenze

5 out of 5
Borgo Pinti, 99, Florence, FI
Fully refundableReserve now, pay when you stay
$1,704 nightly
The price is $1,893 total per night from Aug 14 to Aug 15
$1,893 total
Aug 14 - Aug 15
Total includes taxes and fees
9.6/10 Exceptional! (277 reviews)
"Exceptional Hotel"

Reviewed on Jul 18, 2025

Four Seasons Hotel Firenze
Loggiato dei Serviti

Loggiato dei Serviti

3 out of 5
P.za della SS. Annunziata 3, Florence, FI
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $130 total per night from Jul 30 to Jul 31
$130 total
Jul 30 - Jul 31
Total includes taxes and fees
9.4/10 Exceptional! (382 reviews)
"Absolutely wonderful stay- breakfast was amazing and the building is from the 14th century... room we got wasn't the unexpected but we loved it, and Florence!"

Reviewed on Jul 23, 2025

Loggiato dei Serviti
Hotel Meridiana

Hotel Meridiana

3 out of 5
Viale Don Minzoni 25, Florence, FI
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $79 total per night from Jul 27 to Jul 28
$79 total
Jul 27 - Jul 28
Total includes taxes and fees
7.8/10 Good! (368 reviews)
"The hotel is a good value. It is clean and well located. The staff was very accommodating and allowed us to check in early. I recommend it."

Reviewed on Jul 20, 2025

Hotel Meridiana
See all 461 properties in Santissima Annunziata
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Santissima Annunziata

Accademia Gallery which includes street scenes as well as a large group of people

Gallery of the Academy of Florence

Michelangelo’s David statue is the impressive star of the show at one of Florence’s most popular and well-attended art museums.

Gallery of the Academy of Florence
Statue of David

Statue of David

You can learn about the history of Florence with a stop at Statue of David. Experience the fascinating museums and acclaimed art scene in this vibrant area.

Statue of David
The streets of Florence are dominated by the massive Duomo dome. It is peeking from the end of each street you walk in #firenze

Santissima Annunziata Square

Find out about the history of Florence when you spend time at Santissima Annunziata Square. Experience the acclaimed art scene and fascinating museums in this vibrant area.

Santissima Annunziata Square

Things to do

Micheal Angelo's David

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

$36
per adult
88% of travellers recommend
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
VIP SKIP THE LINE WITH ELVIS : Love the David GUIDED EXPERIENCE

Skip the line : David Guided Experience (Tickets Optional)

$34
per adult
76% of travellers recommend
Skip the line : David Guided Experience (Tickets Optional)
Michaelangelo's David

Accademia timed-entry Ticket with Instant Delivery & Priority Access

$41
per adult
88% of travellers recommend
Accademia timed-entry Ticket with Instant Delivery & Priority Access
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.