Santissima Annunziata Vacations from $1,238
Book a Hotel + Flight or Car together to unlock savings
Your Santissima Annunziata Vacation
Organizing your next travel adventure just got simpler with a vacation package to Santissima Annunziata. Enjoy all this neighborhood has to offer while making incredible memories you'll remember for years. Kick start your trip to Santissima Annunziata with a visit to nearby attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia is here to help put your travel plans into action. Book your ultimate Santissima Annunziata vacation now.
The Latest Santissima Annunziata Vacation Packages
Price found within the past 48 hours. Click for updated prices.
L'Andana
Save 100% on your flight
Price was $3,484, price is now $2,365 per person
$2,365
per person
Sep 25 - Oct 1
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.4/10 Exceptional! (91 reviews)
Breathtaking views of the Tuscan countryside, as well as incredibly attentive staff.
Reviewed on Jun 9, 2026
Grand Hotel Cavour
Historic Centre of Florence
Price was $2,042, price is now $1,448 per person
$1,448
per person
Oct 21 - Oct 25
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,001 reviews)
Beautiful hotel and amazing views from the window! Clean room and the front desk staff were very helpful!
Reviewed on Aug 5, 2026
Precise Tale Poggio Alla Sala
Price was $3,471, price is now $2,496 per person
$2,496
per person
Sep 16 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.6/10 Exceptional! (155 reviews)
The place it’s an Amazing. Very clean. Is more beautiful than the pictures.
Reviewed on Aug 2, 2026
Where to stay in Santissima Annunziata
Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santissima Annunziata Hotel Deals
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
$340 nightly
The price is $393 total per night from Aug 9 to Aug 10
$393 total
Aug 9 - Aug 10
Total with taxes and fees
Four Seasons Hotel Firenze
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
$1,785 nightly
The price is $1,982 total per night from Aug 8 to Aug 9
$1,982 total
Aug 8 - Aug 9
Total with taxes and fees
Hotel Astro Mediceo
Via Frà Bartolommeo 54/56 Florence FI
$67 nightly
The price is $88 total per night from Aug 9 to Aug 10
$88 total
Aug 9 - Aug 10
Total with taxes and fees
8.6/10 Excellent! (376 reviews)
"Tranquilo, seguro y comodo"
Reviewed on Jul 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$28
per adult
76% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$21
per adult
80% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
$133
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.