Santissima Annunziata Vacations from $994
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Your Santissima Annunziata Vacation
Organizing your next travel adventure just got simpler with a vacation package to Santissima Annunziata. Enjoy all this neighborhood has to offer while making incredible memories you'll remember for years. Kick start your trip to Santissima Annunziata with a visit to nearby attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia is here to help put your travel plans into action. Book your ultimate Santissima Annunziata vacation now.
The Latest Santissima Annunziata Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Relais Uffizi, Tailor made Hotel
Historic Centre of Florence
Price was $1,582, price is now $1,222 per person
$1,222
per person
Jan 14 - Jan 20
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Florence (FLR)
9.2/10 Wonderful! (177 reviews)
We loved the location and proximity to major attractions and great restaurants. Breakfast in the morning was delicious and in a lovely space. Our room was spacious, unfortunately it smelled like mildew. Our travel companions had the room next door which did not have the same issue. We also experienced a lot of noise in the middle of the night on two of the four nights we stayed. Overall, I would recommend this hotel, just a different hotel room in the future.
Reviewed on Nov 3, 2026
Donati Luxury Tower Suites
Historic Centre of Florence
Price was $2,754, price is now $1,915 per person
$1,915
per person
Feb 5 - Feb 10
found 3 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Florence (FLR)
9.8/10 Exceptional! (82 reviews)
Great boutique hotel with good size room and bathroom. Very clean and helpful staff. Would definitely stay here again.
Reviewed on Nov 9, 2026
Hotel Duomo Firenze
Historic Centre of Florence
Price was $4,413, price is now $3,147 per person
$3,147
per person
Dec 28 - Jan 2
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,003 reviews)
Amazing location. So cool to be literally across from the Duomo. Easy walk to so many places to shop and eat. Free sparkling and still water was great. Snacks and free gelato! Staff was the most friendly and helpful. Highly recommend this place!
Reviewed on Nov 3, 2026
Where to stay in Santissima Annunziata
Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Historic Centre of Florence
10 out of top 10 points of interest in this area
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza del Duomo and Piazza di Santa Maria Novella are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Santissima Annunziata Hotel Deals
Four Seasons Hotel Firenze
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
$1,126 nightly
The price is $1,256 total per night from Nov 13 to Nov 14
$1,256 total
Nov 13 - Nov 14
Total with taxes and fees
Forte16 View & Spa
Viale Antonio Gramsci 16 Florence FI
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $122 total per night from Dec 13 to Dec 14
$122 total
Dec 13 - Dec 14
Total with taxes and fees
9.6/10 Exceptional! (1,045 reviews)
"Hotel has a great location, good facilities and a ejective attendance. Parking is with an extra fee that could be included considering the price paid by room per day. We add the breakfast and is good. Florence is a very touristy town, beautiful in history and luxury shopping. Thanks!"
Reviewed on Nov 9, 2026
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
$282 nightly
The price is $327 total per night from Dec 13 to Dec 14
$327 total
Dec 13 - Dec 14
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
Florence: Pasta & Tiramisu Cooking Class with Unlimited Wine
$20
per adult
94% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
$26
per adult
74% of travellers recommend
Accademia timed-entry Ticket with App Guide
$44
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.