Santissima Annunziata Vacations from $1,161
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Your Santissima Annunziata Vacation
Organizing your next travel adventure just got simpler with a vacation package to Santissima Annunziata. Enjoy all this neighborhood has to offer while making incredible memories you'll remember for years. Kick start your trip to Santissima Annunziata with a visit to nearby attractions such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia is here to help put your travel plans into action. Book your ultimate Santissima Annunziata vacation now.
The Latest Santissima Annunziata Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Grand Hotel Cavour
Historic Centre of Florence
Price was $2,042, price is now $1,448 per person
$1,448
per person
Oct 21 - Oct 25
found 17 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Florence (FLR)
9.2/10 Wonderful! (1,001 reviews)
Beautiful hotel and amazing views from the window! Clean room and the front desk staff were very helpful!
Reviewed on Aug 5, 2026
Where to stay in Santissima Annunziata
Find the best Santissima Annunziata areas and neighborhoods for the activities you enjoy most. Learn more about Santissima Annunziata
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Santissima Annunziata Hotel Deals
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
$314 nightly
The price is $364 total per night from Aug 10 to Aug 11
$364 total
Aug 10 - Aug 11
Total with taxes and fees
Four Seasons Hotel Firenze
Borgo Pinti, 99 Florence FI
Fully refundableReserve now, pay when you stay
$1,724 nightly
The price is $1,915 total per night from Aug 8 to Aug 9
$1,915 total
Aug 8 - Aug 9
Total with taxes and fees
Hotel Astro Mediceo
Via Frà Bartolommeo 54/56 Florence FI
$69 nightly
The price is $89 total per night from Aug 9 to Aug 10
$89 total
Aug 9 - Aug 10
Total with taxes and fees
8.6/10 Excellent! (376 reviews)
"Tranquilo, seguro y comodo"
Reviewed on Jul 19, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$28
per adult
76% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$21
per adult
80% of travellers recommend
Florence Vespa Tour: Tuscan Hills, Food and Chianti Wine
$133
per adult
100% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.