Santo Domingo Vacations from $706
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The Latest Santo Domingo vacation packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
$1,407
per person
Nov 23 - Nov 29
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (1,006 reviews)
Property was clean and nice, breakfast was excellent.
Reviewed on Oct 20, 2026
Casa Mallet by Wynwood House
Casco Viejo
$2,929
per person
Dec 27 - Jan 1
found 1 day ago
Roundtrip flight included
Kingston (KIN) to Panama City (PTY)
9.8/10 Exceptional! (30 reviews)
I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect.
The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us.
I would stay here again in a heart beat.
It’s a must stay!
Reviewed on Sep 16, 2026
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Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundableReserve now, pay when you stay
$120 nightly
$132 total
Nov 15 - Nov 16
Total with taxes and fees
8.2/10 Very Good! (271 reviews)
"Absolutely beautiful ground! Wonderful staff and a great breakfast! 100% will return!"
Reviewed on Oct 17, 2026
Hotel Dos Rios
43, Nueva California Nueva California
$86 nightly
$94 total
Oct 22 - Oct 23
Total with taxes and fees
Las Olas Resort
Avenida Don Antonio Anguizola Guarumal Chiriqui
Fully refundableReserve now, pay when you stay
$85 nightly
$95 total
Nov 21 - Nov 22
Total with taxes and fees
7.4/10 Good! (340 reviews)
"Understaffed hotel, rooms size according to a beach hotel, beach not recommended for kids or adults without swimming skills."
Reviewed on Sep 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions
How to find the best Santo Domingo package deals?
Finding a cheap Santo Domingo package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, add a couple of filters and see what's available. You can customize your search by "Area," "Amenities," "Property type" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
When to book a vacation package to Santo Domingo?
Secure incredible bargains by reserving your flights early with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Santo Domingo escape.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
