Santo Domingo Vacations from $1,012
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santo Domingo vacation packages
Price found within the past 48 hours. Click for updated prices.
Bambuda Bocas Town - Hostel
$1,012
per person
Nov 11 - Nov 16
found 6 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
8.6/10 Excellent! (62 reviews)
I absolutely loved it here! I stayed 3 nights with my husband and the only regret we had was not upgrading to the king suite. The rooms were clean and beautifully decorated. The restaurant and deck were amazing. The food…let’s have a moment of silence for how incredible the food was. Breakfast was included with our stay and it was really a great deal because everything on the menu was exceptional. The drinks were also phenomenal. Even if you don’t stay here go to the restaurant. There were also daily activities organized by the hotel, like yoga, paddle boarding and a pub crawl. Most nights had live entertainment. I highly recommend this place. I will most certainly stay again.
Reviewed on Oct 7, 2026
Casa Mallet by Wynwood House
Casco Viejo
$2,146
per person
Dec 21 - Dec 28
found 1 day ago
Roundtrip flight included
Bridgetown (BGI) to Panama City (PTY)
9.8/10 Exceptional! (30 reviews)
I would highly recommend, the service I received was impeccable and just a wonderful experience! I was a bit hesitant regarding the location but once I got there, it turned out to be perfect.
The concierge staff was such a pleasure to work with especially ‘Jerry’, who provided recommendations and information. This was such a blessing to us.
I would stay here again in a heart beat.
It’s a must stay!
Reviewed on Sep 16, 2026
Don't see what you're looking for?
See all available trips from Columbus to Santo Domingo
View all tripsSanto Domingo Hotel Deals
Hotel Faranda Bambito Chiriquí, a member of Radisson Individuals
Volcan, Via Cerro Punta Volcan Chiriqui
Fully refundableReserve now, pay when you stay
$109 nightly
$120 total
Oct 15 - Oct 16
Total with taxes and fees
8.2/10 Very Good! (270 reviews)
"Una buena propiedad para alejarse de todo y encontrarse con la naturaleza. Muy buen ambiente y hospitalidad. El personal se portó de maravillas, y fueron muy servicial. Tomé la opción de desayuno incluidos, y muy sabrosos. Me quedé 2 noches en Septiembre 2026. Regresaría de nuevo."
Reviewed on Sep 23, 2026
Hotel Dos Rios
43, Nueva California Nueva California
$86 nightly
$94 total
Oct 10 - Oct 11
Total with taxes and fees
Las Olas Resort
Avenida Don Antonio Anguizola Guarumal Chiriqui
Fully refundableReserve now, pay when you stay
$94 nightly
$103 total
Oct 12 - Oct 13
Total with taxes and fees
7.4/10 Good! (340 reviews)
"Understaffed hotel, rooms size according to a beach hotel, beach not recommended for kids or adults without swimming skills."
Reviewed on Sep 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santo Domingo Vacation Packages
More vacations you might like
Frequently asked questions
How to find the best Santo Domingo package deals?
Finding a cheap Santo Domingo package deal is a breeze with Expedia. Once you've entered your preferred dates and destination under our "Packages" tab, set your budget range, add a couple of filters and see what's available. You can customize your search by "Area," "Amenities," "Property type" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
When to book a vacation package to Santo Domingo?
Secure incredible bargains by reserving your flights early with Expedia. If being spontaneous is more your style, grab one of our last-minute deals for an impromptu Santo Domingo escape.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
