Santo Tomás Vacations from $1,157

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Your Santo Tomás Vacation

Our Santo Tomás vacation packages let you customize your own adventure. Tailor your getaway to suit your interests and needs and make the most of your time in this lively city. If seeing the sights is on the agenda during your trip to Santo Tomás, stop by popular attractions such as Wall of Tears Historical Site. Don't delay exploring this destination any longer. Your dream Santo Tomás vacation is just a few clicks away with Expedia.

The Latest Santo Tomás vacation packages

Price found within the past 48 hours. Click for updated prices.
Campo Duro ecolodge

Campo Duro ecolodge

2.5 out of 5
Price was $1,271, price is now $1,157 per person
$1,157
per person
Jan 14 - Jan 20
found 1 day ago
Roundtrip flight included
Houston (IAH) to José de Villamil Airport (IBB)
No reviews

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What to do in Santo Tomás

Walking Tour to Sierra Negra volcano and Chico Volcano from Isabela Island

Walking Tour to Sierra Negra volcano and Chico Volcano from Isabela Island

$75
per adult
Walking Tour to Sierra Negra volcano and Chico Volcano from Isabela Island
Hiking Tour to Sierra Negra Volcano

Hiking Tour to Sierra Negra Volcano

$67
per adult
100% of travellers recommend
Hiking Tour to Sierra Negra Volcano
Half Day Tintoreras Tour from Isabela Island

Half Day Tintoreras Tour from Isabela Island

$90
per adult
100% of travellers recommend
Half Day Tintoreras Tour from Isabela Island
See all activities in Santo Tomás

Santo Tomás Hotel Deals

Hotel La Laguna Galapagos

Hotel La Laguna Galapagos

3 out of 5
Av. Los Flamingos Puerto Villamil Galapagos
Fully refundableReserve now, pay when you stay
$78 nightly
The price is $86 total per night from Nov 12 to Nov 13
$86 total
Nov 12 - Nov 13
9.2/10 Wonderful! (131 reviews)
"What a wonderful Hotel. Amenities, staff, location are all ideal. Great breakfast. I highly recommend this hotel!"

Reviewed on Nov 9, 2026

Hotel La Laguna Galapagos
HOTEL SIERRA NEGRA

HOTEL SIERRA NEGRA

3 out of 5
Malecon Puerto Villamil Galápagos Islands
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $54 total per night from Nov 18 to Nov 19
$54 total
Nov 18 - Nov 19
8.8/10 Excellent! (64 reviews)
"Literally on the beach. Great views great staff. Very clean!"

Reviewed on Oct 24, 2026

HOTEL SIERRA NEGRA
Iguana Crossing Boutique Hotel

Iguana Crossing Boutique Hotel

3 out of 5
Av. Antonio Gil Puerto Villamil Galapagos
$287 nightly
The price is $316 total per night from Nov 13 to Nov 14
$316 total
Nov 13 - Nov 14
8.8/10 Excellent! (106 reviews)
"Beautiful place. Right on the beach."

Reviewed on Oct 24, 2026

Iguana Crossing Boutique Hotel
See all 87 properties in Santo Tomás
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Tomás Vacation Packages

Santo Tomás Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Top Sights
Sierra Negra and Wall of Tears Historical Site

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Frequently asked questions

How much does a Santo Tomás vacation package cost?
You'll find cheap prices from $1,157 on Expedia for your Santo Tomás getaway. However, factors like the hotel choice, length of stay and season will influence how much your vacation to Santo Tomás costs.
What are the cheapest months to go to Santo Tomás?
If you'd like to book a cheap Santo Tomás vacation package, consider traveling in January, August and December. You'll usually find better rates on hotels and airfares during these months — perfect for budget-conscious travelers.
How many days is enough for Santo Tomás?
Generally, a handful of days is enough to see the main sights during your Santo Tomás vacation. But if you'd like to have more time to rest or take day trips, think about extending your itinerary.
How to find the best Santo Tomás package deals?
Use Expedia's filters to find some fabulous Santo Tomás package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Santo Tomás package deals in the off-season. Switch up your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santo Tomás vacation as a package?
An Expedia vacation package could land you great savings when compared to booking flights and accommodations separately. Better still, you can customize your Santo Tomás escape to fit your exact style. Pick your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santo Tomás?
If you're planning a spur-of-the-moment Santo Tomás adventure, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can find sensational deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santo Tomás vacation packages?
Your Santo Tomás trip is meant to be an escape from your daily routine, not a source of money-related stress. So to allow you a little more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there are no hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.