Santo Tomas Vacations from $495
Book a Hotel + Flight or Car together to unlock savings
Your Santo Tomas Vacation
Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your vacation to Santo Tomas to match your travel style, whatever that may look like.
The Latest Santo Tomas Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Avandaro Golf And Spa
Avandaro
Price was $991, price is now $495 per person
$495
per person
Oct 31 - Nov 3
found 1 day ago
Roundtrip flight included
Tijuana (TIJ) to Toluca (TLC)
8.6/10 Excellent! (995 reviews)
Excelente para desconectarse de la ciudad, excelente atención, restaurante y actividades.
Reviewed on Aug 10, 2025
Collection O Casa Anzures Thematic, Mexico City
Miguel Hidalgo
Save 100% on your flight
Price was $1,831, price is now $987 per person
$987
per person
Oct 22 - Oct 29
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Mexico City (MEX)
8.8/10 Excellent! (116 reviews)
A creative and unique space.
Reviewed on Jul 21, 2025
Casa de la Luz Hotel Boutique
Historic Center
Save 100% on your flight
Price was $1,579, price is now $864 per person
$864
per person
Nov 12 - Nov 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
9.6/10 Exceptional! (385 reviews)
The room was huge and comfortable. On a noisy street but windows and doors were great at sealing noise out. Breakfast was so delicious. Gorgeous old building very well renovated and kept. Very pleased!!!
Reviewed on Sep 13, 2025
Canada Central & Rooftop
Historic Center
Save 100% on your flight
Price was $1,181, price is now $680 per person
$680
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
8.4/10 Very Good! (1,002 reviews)
It was clean and hotel was near restaurants and shops!! I just wish there was a table in the room, since we had to eat our food in the bed. Overall it was a good hotel.
Reviewed on Sep 7, 2025
Where to stay in Santo Tomas
Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
Polanco
4.5/5(491 area reviews)
Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.
Santo Tomas Hotel Deals
Camino Real Aeropuerto Mexico
Mexico City
Fully refundable
$130 nightly
The price is $155 total per night from Oct 7 to Oct 8
$155 total
Oct 7 - Oct 8
Total with taxes and fees
8.6/10 Excellent! (11,156 reviews)
"Practico por la conexión a T1 del AICM"
Reviewed on Sep 15, 2025
Barceló México Reforma
Paseo De La Reforma 1, Mexico City
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $143 total per night from Sep 29 to Sep 30
$143 total
Sep 29 - Sep 30
Total with taxes and fees
9.2/10 Wonderful! (4,827 reviews)
"Es mi segunda vez quedando ami todo el personal son muy amables todo es un 100 me gusta la ubicación todo excelente"
Reviewed on Sep 16, 2025
Fiesta Americana Reforma
Paseo De La Reforma 80, Col. Juarez, Mexico City, CDMX
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $149 total per night from Oct 19 to Oct 20
$149 total
Oct 19 - Oct 20
Total with taxes and fees
9.2/10 Wonderful! (3,675 reviews)
"Friendness, quick access"
Reviewed on Sep 16, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santo Tomas
Paseo de la Reforma
4.5/5(945 reviews)
Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.
Zócalo
4.5/5(2,390 reviews)
This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.
Basilica of Our Lady of Guadalupe
4.5/5(1,720 reviews)
Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.
Things to do
Xochimilco All Inclusive Experience Tequila and Mezcal with Culture
$26
per adult
100% of travellers recommend
Frida Kahlo & Anahuacalli Museum Ticket with Digital Guide
$45
per adult
80% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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- Hospital de Jesus Nazareno
- Visit Azcapotzalco
- Mexico City Arena
- Visit Industrial Vallejo
- La Raza Medical Center
- Planetario Luis Enrique Erro
- Basilica of Our Lady of Guadalupe
- Mexico City Vacations
- Visit Lindavista
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- Visit Polanco
- Visit Downtown Mexico City
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.