Santo Tomas Vacations from $248
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Your Santo Tomas Vacation
Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your vacation to Santo Tomas to match your travel style, whatever that may look like.
The Latest Santo Tomas Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Capital O Collection O Casona De Minas Mineral del Monte
Save 100% on your flight
Price was $451, price is now $248 per person
$248
per person
Oct 2 - Oct 6
found 1 day ago
Roundtrip flight included
Tijuana (TIJ) to Mexico City (MEX)
9.2/10 Wonderful! (354 reviews)
Grata estancia. Todo en orden y calma.
Reviewed on Jul 25, 2025
Casa de la Luz Hotel Boutique
Historic Center
Save 100% on your flight
Price was $1,572, price is now $815 per person
$815
per person
Sep 19 - Sep 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
9.6/10 Exceptional! (377 reviews)
Extremely nice rooms. High ceilings. Great AC. Also excellent restaurant for cocktails.
Reviewed on Aug 16, 2025
La Casa Azul Huasca & Restaurante La Terraza
Save 100% on your flight
Price was $529, price is now $309 per person
$309
per person
Oct 2 - Oct 6
found 1 day ago
Roundtrip flight included
Tijuana (TIJ) to Mexico City (MEX)
9.4/10 Exceptional! (286 reviews)
Great location. However floor along the entrance was uneven. Maybe helping guests with signs to minimize accidents.
Reviewed on Aug 1, 2025
HOTEL LUCA
Roma Norte
Save 100% on your flight
Price was $1,517, price is now $900 per person
$900
per person
Sep 19 - Sep 24
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
9.2/10 Wonderful! (267 reviews)
Staff was wonderful. Area is great. Breakfast and downstairs cafe were great. Easy to get uber. Place is tired and I would liken it to a Best Western. No insulation or double paned windows, so it can be noisy.
Reviewed on Aug 5, 2025
Where to stay in Santo Tomas
Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
Polanco
4.5/5(491 area reviews)
Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.
Santo Tomas Hotel Deals
Barceló México Reforma
Paseo De La Reforma 1, Mexico City
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $133 total per night from Sep 1 to Sep 2
$133 total
Sep 1 - Sep 2
Total includes taxes and fees
9.2/10 Wonderful! (4,750 reviews)
"It is a great hotel option to stay in CDMX. The breakfast options are tasty and the personnel are very friendly."
Reviewed on Aug 18, 2025
Camino Real Aeropuerto Mexico
Mexico City
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $160 total per night from Sep 2 to Sep 3
$160 total
Sep 2 - Sep 3
Total includes taxes and fees
8.6/10 Excellent! (11,013 reviews)
"Due to flight cancellations and airline mixups, I was stranded in the Mexico city airport overnight and this hotel was a lifesaver, especially as I was travelling with two young kids. Facilities are clean Staff is friendly and it’s great to have a hotel in the airport that I can walk to have a clean ..."
Reviewed on Aug 18, 2025
Hyatt Regency Mexico City
Campos Eliseos No. 204 Polanco, Chapultepec, Mexico City
Fully refundableReserve now, pay when you stay
$193 nightly
The price is $231 total per night from Sep 7 to Sep 8
$231 total
Sep 7 - Sep 8
Total includes taxes and fees
9.2/10 Wonderful! (1,160 reviews)
"The ultimate hotel in polanco, got all the amenities you need."
Reviewed on Aug 14, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santo Tomas
Paseo de la Reforma
Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.
Zócalo
This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.
Basilica of Our Lady of Guadalupe
Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.
Things to do
Explore the Real MxCity all-inclusive
$51
per adult
100% of travellers recommend
Xochimilco Trajinera Party with Drinks, Mariachi Music & Taco Dinner
$47
per adult
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- Visit Azcapotzalco
- Mexico City Arena
- Visit Industrial Vallejo
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- Planetario Luis Enrique Erro
- Basilica of Our Lady of Guadalupe
- Mexico City Vacations
- Visit Lindavista
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- Visit Polanco
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.