
Santo Tomas Vacations from $815
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Your Santo Tomas Vacation
Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your vacation to Santo Tomas to match your travel style, whatever that may look like.
The Latest Santo Tomas Vacation Packages

Casa Decu
Reviewed on Dec 3, 2025

Hotel Avandaro Golf And Spa
Reviewed on Oct 12, 2025

Casa de la Luz Hotel Boutique
Reviewed on Nov 30, 2025

Gran Hotel Ciudad de Mexico Zocalo View
Reviewed on Dec 3, 2025

HOTEL LUCA
Reviewed on Dec 3, 2025
Where to stay in Santo Tomas

Roma Norte
Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.
Santo Tomas Hotel Deals

Camino Real Aeropuerto Mexico
I liked everything
Reviewed on Dec 4, 2025

Barceló México Reforma
What I like the most about this property is that the staff was friendly, knowledgeable, caring, respectful, prompt and respectful.
Reviewed on Nov 29, 2025

Galeria Plaza Reforma
El Hotel está muy bien ubicado! El personal muy amable. Solo necesitan mejorar con la limpieza un poco.
Reviewed on Nov 30, 2025
Discover the most popular places to visit in Santo Tomas

Paseo de la Reforma
Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Angel of Independence Monument
Gaze upon this tall and majestic structure that symbolizes for the whole nation’s citizens the country’s long struggle for independence.

Basilica of Our Lady of Guadalupe
Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.
Things to do

Frida Kahlo Museum Skip-the-line Tickets with Digital Guide
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