Santo Tomas Vacations from $885

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Your Santo Tomas Vacation

Entertainment, food, art and more … There's a whole lot to discover with a Santo Tomas vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's hard to forget. If your trip to Santo Tomas includes some sightseeing, hit up well-known attractions like Zócalo, Angel of Independence Monument and Basilica of Our Lady of Guadalupe. Expedia will help you escape your daily routine. Tailor your vacation to Santo Tomas to match your travel style, whatever that may look like.

The Latest Santo Tomas Vacation Packages

Price found within the past 48 hours. Click for updated prices.
AR 218 Hotel by ULIV

AR 218 Hotel by ULIV

4 out of 5
La Condesa
Save 100% on your flight
Price was $1,933, price is now $885 per person
$885
per person
Jun 18 - Jun 21
found 9 hours ago
Roundtrip flight included
Burbank (BUR) to Mexico City (MEX)
9.4/10 Exceptional! (1,131 reviews)
Awesome stay. The staff were amazingly helpful and made our stay very enjoyable. We got a Swedish massage done right in our rooms and overall we love the whole experience

Reviewed on May 4, 2026

ULIV Apartments Polanco

ULIV Apartments Polanco

4 out of 5
Miguel Hidalgo
Price was $2,336, price is now $915 per person
$915
per person
Jun 17 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Mexico City (MEX)
8.8/10 Excellent! (359 reviews)
Staff was very helpful

Reviewed on May 4, 2026

ULIV Park Polanco

ULIV Park Polanco

3 out of 5
Polanco
Price was $3,317, price is now $1,481 per person
$1,481
per person
Jun 17 - Jun 22
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (QLA) to Mexico City (MEX)
9.4/10 Exceptional! (111 reviews)
This was the ideal place to stay in Mexico City. The apartment was so quiet, clean, and comfortable. The staff was friendly and responsive to all our needs. We went to the restaurant Toscano Polanco just down the street four times because it was so good as was the popular yogurt place next door. The neighborhood, which online was called the Beverly Hills of Mexico City, matched the billing. So safe and clean.

Reviewed on Apr 30, 2026

ULIV Parque México

ULIV Parque México

3 out of 5
La Condesa
Price was $2,710, price is now $1,220 per person
$1,220
per person
Jun 16 - Jun 21
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Mexico City (MEX)
9.2/10 Wonderful! (124 reviews)
The apartment was beautiful and spacious. It’s well located. Everyone who worked there was super friendly and helpful. My only complaint is that the hot water lasts about 3 mins max, I couldn’t even wash my hair- we had to be out of the showers within 3 mins.

Reviewed on Apr 8, 2026

Galeria Plaza Reforma

Galeria Plaza Reforma

4 out of 5
Reforma
Save 100% on your flight
Price was $2,960, price is now $1,387 per person
$1,387
per person
Jun 28 - Jul 4
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Mexico City (MEX)
9.4/10 Exceptional! (3,463 reviews)
Great hotel, nice rooftop area to hang out, was here with a group of friends visiting. Felt welcome by the hotel with no issues. Close proximity to everything

Reviewed on May 4, 2026

Where to stay in Santo Tomas

Find the best Santo Tomas areas and neighborhoods for the activities you enjoy most. Learn more about Santo Tomas
The Cibeles fountain in Mexico City is an exact replica of the Cibeles fountain that is located in the Plaza de Cibeles in Madrid, Spain

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Find hotels in Roma Norte

Santo Tomas Hotel Deals

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

4 out of 5
Mexico City
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $147 total per night from May 25 to May 26
$147 total
May 25 - May 26
Total with taxes and fees
8.8/10 Excellent! (12,866 reviews)
My experience with the hotel was terrible I couldn't sleep with such a terrible too soft bed and pillows all night I had a strong neck pain because of the conditions of the bed and the restaurant had such a bad meal that the next day I had diarrhea with that bad food and my trip was terrible because ...

Reviewed on May 7, 2026

Camino Real Aeropuerto Mexico
Fiesta Americana Reforma

Fiesta Americana Reforma

4 out of 5
Paseo De La Reforma 80 Mexico City CDMX
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $149 total per night from May 15 to May 16
$149 total
May 15 - May 16
Total with taxes and fees
9.2/10 Wonderful! (4,760 reviews)
I love this hotel! It’s beautiful, and staff is very friendly. The location is incredible, everything is close by. I loved the room and the beautiful view. The food and drinks were amazing. I recommend this hotel 100%

Reviewed on May 6, 2026

Fiesta Americana Reforma
Barceló México Reforma

Barceló México Reforma

4.5 out of 5
Paseo De La Reforma 1 Mexico City
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $158 total per night from May 26 to May 27
$158 total
May 26 - May 27
Total with taxes and fees
9.4/10 Exceptional! (5,368 reviews)
Rooms were very spacious, nice and the room service was excellent. Staff were very sweet. Would recommend. Gym space was very nice and fully functional- you could do everything except power lift. Restaurants in the hotel very nice. Bathroom was spacious The only cons: bed was lumpy and the swimming ...

Reviewed on May 6, 2026

Barceló México Reforma
See all 6,003 properties in Santo Tomas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Santo Tomas

Paseo de la Reforma

Paseo de la Reforma

Like the Champs Elysées in Paris, this famous wide avenue provides a distinctive elegance to the historic plan of this huge global city.

Paseo de la Reforma
Basilica of Our Lady of Guadalupe

Basilica of Our Lady of Guadalupe

Mexico’s patron saint, the Virgin of Guadalupe, is believed to have appeared on the site of this church, making it an important pilgrimage site for many Catholics.

Basilica of Our Lady of Guadalupe
Zócalo

Zócalo

This is the heart of Mexico City with wide-ranging architecture, cultural events and a lively arts scene.

Zócalo

Things to do

Teotihuacan Exclusive Early Access, Tlatelolco & Liquors Tasting

Teotihuacan Guided Tour with Early Access and Optional Lunch

$42
per adult
90% of travellers recommend
Teotihuacan Guided Tour with Early Access and Optional Lunch
MEXICAN WRESTLING TOUR WITH TACOS AFTER SHOW N MEXICO CITY

Mexican Wrestling Tour with Tacos and After Show in Mexico City

$120
per traveler
Mexican Wrestling Tour with Tacos and After Show in Mexico City
See all activities in Mexico City

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.